Physics Beyond the Standard Model and Cosmological Connections: A Summary from LCWS 06

The International Linear Collider (ILC) is likely to provide us important insights into the sector of physics that may supersede our current paradigm viz., the Standard Model. In anticipation of the possibility that the ILC may come up in the middle of the next decade, several groups are vigourously investigating its potential to explore this new sector of physics. The Linear Collider Workshop in Bangalore (LCWS06) had several presentations of such studies which looked at supersymmetry, extra dimensions and other exotic possibilities which the ILC may help us discover or understand. Some papers also looked at the understanding of cosmology that may emerge from studies at the ILC. This paper summarises these presentations.Comment: 8 pages (including cover page) LaTeX, Summary talk presented at the International Linear Collider Workshop in Bangalore, India in March 200

Large extra dimension effects in Higgs boson production at linear colliders and Higgs factories

In the framework of quantum gravity propagating in large extra dimensions, the effects of virtual Kaluza-Klein graviton and graviscalar interference with Higgs boson production amplitudes are computed at linear colliders and Higgs factories. The interference of the almost-continuous spectrum of the KK gravitons with the standard model resonant amplitude is finite and predictable in terms of the fundamental D-dimensional Plank scale M_D and the number of extra dimensions \delta. We find that, for M_D ~ 1 TeV and \delta=2, effects of the order of a few percent could be detected for heavy Higgs bosons (m_H>500 GeV) in Higgs production both via WW fusion in e^+e^- colliders and at \mu^+\mu^- Higgs-boson factories.Comment: 16 pages, 2 figures ; a few comments and references added ; version to appear in JHE

Using Tau Polarization to Discriminate between SUSY Models and Determine SUSY Parameters at ILC

In many SUSY models the first SUSY signal in the proposed International Linear Collider is expected to come from the pair production of $\tilde\tau_1$, followed by its decay into $\tau$+LSP. We study a simple and robust method of measuring the polarization of this $\tau$ in its 1-prong hadronic decay channel,and show how it can be used to discriminate between SUSY models and to determine SUSY parameters.Comment: 9 pages, 5 figures, minor corrections; version published in Phys. Lett.

Radiative production of invisible charginos in photon photon collision

If in a supersymmetric model, the lightest chargino is nearly degenerate with the lightest neutralino, the former can decay into the latter alongwith a soft pion (or a lepton-neutrino pair). Near degeneracy of the chargino and neutralino masses can cause the other decay products (the pion or the lepton) to be almost invisible. Photon-photon colliders offer a possibility of clean detection of such an event through a hard photon tag.Comment: 12 pages, 5 postscript figure

The first microbial colonizers of the human gut: composition, activities, and health implications of the infant gut microbiota

The human gut microbiota is engaged in multiple interactions affecting host health during the host's entire life span. Microbes colonize the neonatal gut immediately following birth. The establishment and interactive development of this early gut microbiota are believed to be (at least partially) driven and modulated by specific compounds present in human milk. It has been shown that certain genomes of infant gut commensals, in particular those of bifidobacterial species, are genetically adapted to utilize specific glycans of this human secretory fluid, thus representing a very intriguing example of host-microbe coevolution, where both partners are believed to benefit. In recent years, various metagenomic studies have tried to dissect the composition and functionality of the infant gut microbiome and to explore the distribution across the different ecological niches of the infant gut biogeography of the corresponding microbial consortia, including those corresponding to bacteria and viruses, in healthy and ill subjects. Such analyses have linked certain features of the microbiota/microbiome, such as reduced diversity or aberrant composition, to intestinal illnesses in infants or disease states that are manifested at later stages of life, including asthma, inflammatory bowel disease, and metabolic disorders. Thus, a growing number of studies have reported on how the early human gut microbiota composition/development may affect risk factors related to adult health conditions. This concept has fueled the development of strategies to shape the infant microbiota composition based on various functional food products. In this review, we describe the infant microbiota, the mechanisms that drive its establishment and composition, and how microbial consortia may be molded by natural or artificial interventions. Finally, we discuss the relevance of key microbial players of the infant gut microbiota, in particular bifidobacteria, with respect to their role in health and disease

A pilot randomised double blind controlled trial of the efficacy of purified fatty acids for the treatment of women with endometriosis-associated pain (PurFECT):study protocol

Abstract Background Endometriosis affects 6–10% of women and is associated with debilitating pelvic pain. It costs the UK > £2.8 billion per year in loss of productivity. Endometriosis can be managed by surgical excision or medically by ovarian suppression. However, ~ 75% symptoms recur after surgery and available medical treatments have undesirable side effects and are contraceptive. Omega-3 purified fatty acids (PUFA) have been shown in animal models to reduce factors that are thought to lead to endometriosis-associated pain, have minimal side effects, and no effects on fertility. This paper presents a protocol for a two-arm, pilot parallel randomised controlled trial (RCT) which aims to inform the planning of a future multicentre trial to evaluate the efficacy of Omega-3 PUFA in the management of endometriosis-associated pain in women. Methods The study will recruit women with endometriosis over a 12-month period in the National Health Service (NHS) Lothian, UK, and randomise them to 8 weeks of treatment with Omega-3 PUFA or comparator (olive oil). The primary objective is to assess recruitment and retention rates. The secondary objectives are to determine the effectiveness/acceptability to participants of the proposed methods of recruitment/randomisation/treatments/questionnaires, to inform the sample size calculation and to refine the research methodology for a future large randomised controlled trial. Response to treatment will be monitored by pain scores and questionnaires assessing physical and emotional function compared at baseline and 8 weeks. Discussion We recognise that there may be potential difficulties in mounting a large randomised controlled trial for endometriosis to assess Omega-3 PUFA because they are a dietary supplement readily available over the counter and already used by women with endometriosis. We have therefore designed this pilot study to assess practical feasibility and following the ‘Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials’ recommendations for the design of chronic pain trials. Trial registration ISRCTN4420234

Single Photon Signals for Warped Quantum Gravity at a Linear e+-e- Collider

We study the `single photon' process e+- e- -> gamma nu nubar with contributions due to exchange of massive gravitons in the Randall- Sundrum model of low-scale quantum gravity. It is shown that for significant regions in the parameter space, this process unambiguously highlights the resonance structure of the graviton sector. Even in the non-resonant part of the parameter space, we show that comparison with the benchmark process e+- e- -> mu+- mu- can clearly distinguish signals for warped gravity from similar signals for large extra dimensions.Comment: Published version; figures change

Physics Possibilities at a Linear Collider

We review some recent studies about the parameter determination of top quarks, W bosons, Higgs bosons, supersymmetric particles and in the ADD model of extra dimensions at a linear collider.Comment: 16 pages, LaTeX, 9 eps figures, invited plenary talk presented by A. Bartl at the "Workshop on High Energy Physics Phenomenology (WHEPP-8)", Indian Institute of Technology, Mumbai, January 5 - 16, 200