Effects of Foam Rolling on Range of Motion and Vertical Jump Height

Static stretching has been shown to elicit an acute improvement in range of motion (ROM) in both the contralateral and ipsilateral limb. However, static stretching has also been shown to impair performance. Foam rolling has been used in clinical settings as well as by the general population to increase ROM without impairing performance. To date, there is limited research evaluating the effect of foam rolling on the contralateral limb. Therefore, the purpose of this study was to explore the effect of foam rolling on ROM and single-leg drop jump performance in the foam rolled and non-foam rolled legs. The results of this study may help to understand the mechanism through which foam rolling can improve ROM

The making of a civic discourse on controversial historical past: from denial to parrhesia

This contribution discusses the pragmatic effects of different rhetoric strategies conveying evidence of past ingroup violence after a long lasting social denial (Cohen, 2001). In particular, a case study is presented on the making of a civic discourse on controversial historical past: war crimes committed by the Italian Army during the colonial invasion of Ethiopia (1935-36). Although very well proved (Del Boca, 2005), these facts were only recently inserted in Italian history textbooks (Leone & Mastrovito, 2010; Cajani, 2013). In this same period, evidence of these crimes was officially presented during discussions of the Italian Parliament. In spite of these recent acknowledgments of the Italian responsibilities for these crimes, a social myth is still widely shared by the public opinion, representing Italians as good fellows (Italiani, brava gente: cfr. Del Boca, 2005), unable to be cruel both in everyday life and in wartimes (Volpato et al., 2012). This specific situation, denying even the reality of facts happened, has been defined literal social denial, i.e. the deepest among the three possible states of denial (literal, interpretive, implicative: cfr. Cohen, 2001). The issue of literal social denial of past ingroup violence is at the intersection among theories on narratives on national past (László, 2003), social representations of history (Liu et al., 2014), conflict ethos (Bar-Tal et al., 2012; Kelman, 2008), group-based emotions (Allpress et al., 2010; Leone, 2000) and intergroup reconciliation processes (Nadler et al., 2008). Namely, understanding how a social denial could break down implies the theorization of human mind’s reflexivity as grounded on historical awareness (Ortega y Gasset, 1930), and the notion of social change as primarily rooted in natality, i.e. the fact that each birth represents a new beginning (Arendt, 1958). Drawing on this theoretical background, we will present an ongoing research program (Leone, in press) on the literal social denial (Cohen, 2001) of war crimes committed by the Italian army during colonial period and on the pragmatic effects of different kinds of communication on this controversial past. In order to address this issue, we will particularly focus on the concept of parrhesia as defined by Foucault (1983): the communicative choice of «frankness instead of persuasion, truth instead of falsehood or silence, [...] the moral duty instead of self-interest and moral apathy » (Foucault, 2001, p.19). Studies we conducted in this line tested the change in beliefs and the emotional reactions of young citizens confronted with mild or parrhesiastic descriptions of socially denied war crimes (Leone & Sarrica, 2014, 2012). Empirical evidence will be discussed in order to reflect on our core idea: that a parrhesiastic communication is a risky tough necessary pragmatic move to break long lasting denial of ingroup wrongdoings, to trigger critical civic discourse in the place of social myths and to start reconciliation processes

Se gli inumani siamo noi. Riflessioni sulla narrazione intergenerazionale dei crimini di guerra commessi dal gruppo di appartenenza

Riassunto - L’articolo riflette sui fattori che facilitano l’elaborazione delle memorie collettive di gravi e ingiustificabili violenze commesse dal proprio gruppo, soffermandosi sul ruolo delle narrazioni intergenerazionali rivolte ai discendenti di un gruppo che si è reso responsabile di crimini di guerra. Anche se molto difficili, tali narrazioni sono indispensabili per non bloccarsi in una situazione di falsa riconciliazione. Dopo la firma della pace, i processi psico-sociali che portano a una vera riconciliazione proseguono infatti, in modo fragile e facilmente reversibile, per diverse generazioni, fino a che l’immagine del nemico non sia stata marginalizzata dall’auto-definizione sociale delle persone comuni dei gruppi coinvolti dalla guerra. Ciò comporta l’elaborazione di un lutto simbolico rispetto all’umanità del proprio gruppo da parte dei membri del gruppo maggiormente responsabile della violenza, diverso dal lutto simbolico relativo alla capacità del proprio gruppo di controllare il proprio destino, elaborato dei membri del gruppo delle vittime. Le più intense reazioni emotive negative e l’espressione di una maggiore volontà di aiuto verso i discendenti del gruppo delle vittime, registrate in 103 studenti universitari italiani che avevano letto una storia chiara (vs. evasiva) dei crimini di guerra commessi dall’Italia in Etiopia nel 1935-36, suggeriscono che una narrazione esplicita delle disumanità del proprio gruppo possa favorire questi processi di elaborazione. Parole chiave: narrative intergenerazionali, rappresentazione sociale della storia nazionale, memorie collettive, riconciliazione tra i gruppi, crimini di guerra. When we are the Inhumane. Reflections on Intergenerational Narratives of War Crimes Committed by the IngroupAbstract - This article focuses on factors that may facilitate intergroup reconciliation. In this frame, intergenerational narratives intended for descendants of a group charged with war crimes are considered in depth. Although heavy burdens, these narratives are necessary to avoid false reconciliations. Intergroup reconciliation requires, in fact, that several generations elaborate a symbolic loss, which forms a part of their in-group identity. For descendents of the group that is more responsible  for  war violence, this identity loss relates to the human dignity of their group. Results of empirical research, in which 103 Italian university students read a narrative describing overtly (vs. evasive) war crimes enacted by the Italian Army during the invasion of Ethiopia (1935-36), suggest that explicit narratives of inhuman acts committed by one’s own group may facilitate this kind of reconciliation.Keywords: Intergenerational Narratives; Social Representation of National History; Collective Memories; Intergroup Reconciliation; War Crimes

The chaperone system in cancer therapies: Hsp90

: The chaperone system (CS) of an organism is composed of molecular chaperones, chaperone co-factors, co-chaperones, and chaperone receptors and interactors. It is present throughout the body but with distinctive features for each cell and tissue type. Previous studies pertaining to the CS of the salivary glands have determined the quantitative and distribution patterns for several members, the chaperones, in normal and diseased glands, focusing on tumors. Chaperones are cytoprotective, but can also be etiopathogenic agents causing diseases, the chaperonopathies. Some chaperones such as Hsp90 potentiate tumor growth, proliferation, and metastasization. Quantitative data available on this chaperone in salivary gland tissue with inflammation, and benign and malignant tumors suggest that assessing tissue Hsp90 levels and distribution patterns is useful for differential diagnosis-prognostication, and patient follow up. This, in turn, will reveal clues for developing specific treatment centered on the chaperone, for instance by inhibiting its pro-carcinogenic functions (negative chaperonotherapy). Here, we review data on the carcinogenic mechanisms of Hsp90 and their inhibitors. Hsp90 is the master regulator of the PI3K-Akt-NF-kB axis that promotes tumor cell proliferation and metastasization. We discuss pathways and interactions involving these molecular complexes in tumorigenesis and review Hsp90 inhibitors that have been tested in search of an efficacious anti-cancer agent. This targeted therapy deserves extensive investigation in view of its theoretical potential and some positive practical results and considering the need of novel treatments for tumors of the salivary glands as well as other tissues

President Obama’s Humble Face: An Authentic or a Socially Desirable Posturing? A Study on Reactions to Obama’s Autobiographical Self-Disclosures

Referring to the mainstream studies based on the personalization’s hypothesis, which positively evaluates signals of dominance shown by leaders, the analysis of Obama’s rhetoric stays a relevant exception. His risky recall, during his political talks, of his social difficulties as a child of a mixed couple was in fact one of the more surprising aspects of his success. Nevertheless, reactions to his autobiographical sharing were scarcely explored. Based on the idea that these self-disclosures signal his responsivity toward the audience of low social condition and can, therefore, be defined as a sign of humility, this research aims to test if coherence between Obama’s words and his facial expressions of contempt, due to the seriousness of social injustices endured in his childhood, may influence the receivers’ perception of such unexpected communication. Before reading a brief autobiographical sharing taken from a “Back-to-school” speech, a highly ritualized monolog the US President addresses each year to students, 175 Italian participants were presented with a photo of Obama displaying either an expression of contempt (taken from the video of the speech) or a neutral expression. Comparisons between self-assessments of perceptions and reactions of participants assigned to the two experimental conditions show that a facial expression of contempt, coherent with words describing his school difficulties, has been crucial for perceiving this humble political discourse as authentic and not as a simple socially desirable posturing. More studies seem to be needed, however, to understand how humble speech could enhance the positive face of leaders or backfire against them

Deciphering metal-induced oxidative damages on glycated albumin structure and function

Background: Metal ions such as copper or zinc are involved in the development of neurodegenerative pathologies and metabolic diseases such as diabetes mellitus. Albumin structure and functions are impaired following metal- and glucose-mediated oxidative alterations. The aim of this study was to elucidate effects of Cu(II) and Zn(II) ions on glucose-induced modifications in albumin by focusing on glycation, aggregation, oxidation and functional aspects. Methods: Aggregation and conformational changes in albumin were monitored by spectroscopy, fluorescence and microscopy techniques. Biochemical assays such as carbonyl, thiol groups, albumin-bound Cu, fructosamine and amine group measurements were used. Cellular assays were used to gain functional information concerning antioxidant activity of oxidized albumins. Results: Both metals promoted inhibition of albumin glycation associated with an enhanced aggregation and oxidation process. Metal ions gave rise to the formation of β-amyloid type aggregates in albumin exhibiting impaired antioxidant properties and toxic activity to murine microglia cells (BV2). The differential efficiency of both metal ions to inhibit albumin glycation, to promote aggregation and to affect cellular physiology is compared. Conclusions and general significance: Considering the key role of oxidized protein in pathology complications, glycation-mediated and metal ion-induced impairment of albumin properties might be important parameters to be followed and fought. © 2013 Elsevier B.V

Investigating the Lytic Staphylococcus aureus Bacteriophage Reservoir Amongst a South Carolina University Population: Discovery, Characterization, and Identification of a Potential Bacteriophage Treatment for Methicillin-Resistant Staphylococcus aureus

Bacteriophages are viruses that only infect bacterial cells and can be used to treat antibiotic resistant bacterial infections. This study focused on the isolation and characterization of bacteriophages lytic to Staphylococcus aureus at Coastal Carolina University (CCU) in Conway, South Carolina, as a means to isolate bacteriophages that can potentially be used to treat methicillin-resistant Staphylococcus aureus (MRSA), an antibiotic-resistant S. aureus variant. From 2014 to 2018, collection of ear and nose samples from 225 randomly selected CCU volunteers was conducted. Filter sterilization, amplification, microbial tests, and PCR analyses were performed in order to identify and characterize bacteriophages. Coliphage populations were also monitored as an indicator of temporal competition and fecal contamination. A pilot study was initiated in 2017 in which 15 CCU volunteers were sampled once a month from October 2017 through March 2018 in order to investigate coliphage and S. aureus phage population dynamics. The purpose of this study was to gain insight into the lytic Staphylococcus aureus phage repository found in the CCU community, and to explore S. aureus phage dynamics amongst the CCU populace. Results indicated that a considerable S. aureus and E. coli phage reservoir exists amongst the CCU population. Most phages could not be characterized via PCR analysis, suggesting high diversity. The preliminary study indicated that S. aureus and E. coli hosts potentially exhibit temporal competition, of which might be explanatory of phage population fluctuations

The intergenerational memory of a cultural heritage as a means of promoting citizens’ sense of community

Community psychology increasingly emphasizes the importance of cultural heritage, especially in local communities. This study suggests that the reconstruction of autobiographical memory associated with cultural heritage can become a resource for consolidating a sense of community. Therefore, we have highlighted the link between memory recall and a sense of community through which it is possible to observe how memory recall can be a means of giving positive meaning to one’s membership. The study focuses on San Cesario in Lecce in southeastern Italy, an Apulian local community known for its archaeological industrial heritage, i.e., its distilleries. The participants of the study were 29 citizens of San Cesario of different gender and age, who were interviewed. The transcription of the interviews was followed by a content analysis in which the evoked dimensions of the sense of community and the types of memory, such as place or autobiographical ones, were noted. The results showed that intergenerational memory of cultural heritage can be a way of renewing the meanings associated with feelings of belonging to a local community, but also a way of recovering conflicted and ambivalent memories in order to promote psychosocial empowerment