5,253 research outputs found
R-parity as a residual gauge symmetry : probing a theory of cosmological dark matter
We present a non-supersymmetric scenario in which the R-parity symmetry arises as a result of spontaneous gauge symmetry breaking,
leading to a viable Dirac fermion WIMP dark matter candidate. Direct detection
in nuclear recoil experiments probes dark matter masses around TeV for
TeV consistent with searches at the LHC, while lepton
flavor violation rates and flavor changing neutral currents in neutral meson
systems lie within reach of upcoming experiments.Comment: 7 pages, 3 figure
Exactly quantized dynamics of classical incommensurate sliders
We report peculiar velocity quantization phenomena in the classical motion of
an idealized 1D solid lubricant, consisting of a harmonic chain interposed
between two periodic sliders. The ratio v_cm/v_ext of the chain center-of-mass
velocity to the externally imposed relative velocity of the sliders stays
pinned to exact "plateau" values for wide ranges of parameters, such as sliders
corrugation amplitudes, external velocity, chain stiffness and dissipation, and
is strictly determined by the commensurability ratios alone. The phenomenon is
explained by one slider rigidly dragging the kinks that the chain forms with
the other slider. Possible consequences of these results for some real systems
are discussed.Comment: 5 pags 4 fig
Continuum and discrete models for structures including (quasi-) inextensible elasticae with a view to the design and modeling of composite reinforcements
Inspired by some composite fiber reinforcements used in aeronautical engineering and by the need of conceiving new metamaterials, some discrete models including (quasi-) inextensible elasticae are considered. A class of continuum models approximately describing the macroscopic mechanical behavior of introduced structures is then heuristically proposed. Some of these continuum models can be regarded as a special kind of second-gradient elastic media, in which the higher-gradient elasticity is conferred by the flexural stiffnesses of elasticae constituting the microscopic lattice. The discrete models are studied by means of suitably tailored numerical codes designed to avoid numerical instabilities and locking and a comparison of discrete versus continuum models is attempted. The obtained results show that the theory of generalized continua may be useful in some engineering applications and it plays a relevant role in the mechanics of woven composites. The introduced discrete and continuum models are used to describe the so-called bias extension test on woven fabrics and it is shown that a good choice to correctly reproduce the targeted phenomenology is to use a second gradient continuum theory. However, as discussed throughout the paper, in the context of rigorous micro-macro identification procedures there still remain many open problems to be solved, especially when dealing with systems subjected to particular constraints, such as inextensibility. © 2014 Elsevier Ltd
Natural disasters and university enrolment: Evidence from L’Aquila earthquake
Although there are several studies looking at the effect of natural disasters on economic growth, less attention has been dedicated to their impact on educational outcomes, especially in more developed countries. We use the synthetic control method to examine how the L’Aquila earthquake affected subsequent enrolment at the local university. This issue has wide economic implications as the University of L’Aquila made a large contribution to the local economy before the earthquake. Our results indicate that the earthquake had no statistically significant effect on first-year enrolment at the University of L’Aquila in the three academic years after the disaster. This natural disaster, however, caused a compositional change in the first-year student population, with a substantial increase in the number of students aged 21 or above. This is likely to have been driven by post-disaster measures adopted in order to mitigate the expected negative effects on enrolment triggered by the earthquake
Assessment of a Hydrogen-Fueled Heavy-Duty Yard Truck for Roll-On and Roll-Off Port Operations
The port-logistic industry has a significant impact on the urban environment nearby ports and on the surrounding coastal areas. This is due to the use of large auxiliary power systems on ships operating during port stays, as well as to the employment of a number of fossil fuel powered road vehicles required for port operations. The environmental impact related to the use of these vehicles is twofold: on one hand, they contribute directly to port emissions by fuel consumption; on the other hand, they require some of the ship auxiliary systems to operate intensively, such as the ventilation system, which must operate to remove the pollutants produced by the vehicle engines inside the ship. The pathway to achieve decarbonization and mitigation of energy use in ports involves therefore the adoption of alternative and cleaner technology solutions for the propulsion systems of such port vehicles. This paper presents the performance analysis of a hydrogen powered cargo-handling vehicle for roll-on and roll-off port operations in a real case scenario. The fuel cell/battery hybrid powertrain of the vehicle has been previously designed by the authors. On the base of real data acquired during an on-field measurement campaign, and by means of a validated numerical model of the vehicle dynamics, different mission profiles are defined, in terms of driving and duty cycles, in order to represent typical port operations. A rule-based energy management strategy is then used to estimate the energy and hydrogen consumptions required by the vehicle and to assess its suitability to accomplish the defined target port operations. Outputs from this study show the potential of the proposed solution to take the place, in a foreseeable future, of conventional Diesel-engine vehicles, today commonly used in port logistics, towards a zero-emission scenario
Real-Time Wavelet-transform spectrum analyzer for the investigation of 1/f^\alpha noise
A wavelet transform spectrum analyzer operating in real time within the
frequency range 3X10^(-5) - 1.3X10^5 Hz has been implemented on a low-cost
Digital Signal Processing board operating at 150MHz. The wavelet decomposition
of the signal allows to efficiently process non-stationary signals dominated by
large amplitude events fairly well localized in time, thus providing the
natural tool to analyze processes characterized by 1/f^alpha power spectrum.
The parallel architecture of the DSP allows the real-time processing of the
wavelet transform of the signal sampled at 0.3MHz. The bandwidth is about
220dB, almost ten decades. The power spectrum of the scattered intensity is
processed in real time from the mean square value of the wavelet coefficients
within each frequency band. The performances of the spectrum analyzer have been
investigated by performing Dynamic Light Scattering experiments on colloidal
suspensions and by comparing the measured spectra with the correlation
functions data obtained with a traditional multi tau correlator. In order to
asses the potentialities of the spectrum analyzer in the investigation of
processes involving a wide range of timescales, we have performed measurements
on a model system where fluctuations in the scattered intensities are generated
by the number fluctuations in a dilute colloidal suspension illuminated by a
wide beam. This system is characterized by a power-law spectrum with exponent
-3/2 in the scattered intensity fluctuations. The spectrum analyzer allows to
recover the power spectrum with a dynamic range spanning about 8 decades. The
advantages of wavelet analysis versus correlation analysis in the investigation
of processes characterized by a wide distribution of time scales and
non-stationary processes are briefly discussed.Comment: 12 pages, 6 figure
Regge calculus and Ashtekar variables
Spacetime discretized in simplexes, as proposed in the pioneer work of Regge,
is described in terms of selfdual variables. In particular, we elucidate the
"kinematic" structure of the initial value problem, in which 3--space is
divided into flat tetrahedra, paying particular attention to the role played by
the reality condition for the Ashtekar variables. An attempt is made to write
down the vector and scalar constraints of the theory in a simple and
potentially useful way.Comment: 10 pages, uses harvmac. DFUPG 83/9
FOLFOX activity in a rare case of metastatic colonic adenocarcinoma of the tongue: A case report
Abstract Background Adenocarcinomas of the oral cavity are rare neoplasms, and only four cases of primary colonic adenocarcinoma of the tongue have ever been described in literature. Very few information about chemotherapy sensitiveness of this type of neoplasia is available, with only one regimen that showed some activity in a metastatic patient. Case presentation We describe the case of a patient bearing a metastatic colonic adenocarcinoma of the tongue submitted to a first-line chemotherapy with oxaliplatin, 5-fluorouracil and folinic acid (FOLFOX regimen). After chemotherapy the patient obtained the complete disappearance of the primitive neoplasia located in the body of the tongue, and a tumor size reduction > 50% of liver and lung metastases. Conclusions This case demonstrated the activity of the combination of oxaliplatin and 5-fluorouracil in this very rare neoplasia. The FOLFOX regimen might be considered either in advanced and especially in the neoadjuvant setting, when the reduction of the primary tumor is highly needed
Multifractal properties of return time statistics
Fluctuations in the return time statistics of a dynamical system can be
described by a new spectrum of dimensions. Comparison with the usual
multifractal analysis of measures is presented, and difference between the two
corresponding sets of dimensions is established. Theoretical analysis and
numerical examples of dynamical systems in the class of Iterated Functions are
presented.Comment: 4 pages, 3 figure
The Differential Efficacy of Pemetrexed According to NSCLC Histology: A Review of Two Phase III Studies
Abstract
Background.
Recent studies of pemetrexed have identified a predictive role for non-small cell lung cancer (NSCLC) histology. We further reviewed the differential efficacy of pemetrexed according to histology in two large, phase III NSCLC trials.
Methods.
One study tested pemetrexed versus docetaxel in previously treated patients (n = 571) and the other tested cisplatin plus pemetrexed versus cisplatin plus gemcitabine in chemotherapy-naive patients (n = 1,725) with advanced NSCLC. Cox proportional hazard models were used to test for covariate-adjusted treatment-by-histology interactions (THIs) for overall survival (OS) and progression-free survival (PFS). For each histologic subgroup, the Kaplan–Meier method was used to estimate unadjusted within-arm medians, and Cox models were used to estimate covariate-adjusted between-arm hazard ratios (HRs).
Results.
In both studies, treatment arms were well balanced for histology. THIs were statistically significant (p < .005) for both OS and PFS. Nonsquamous patients treated with pemetrexed-based therapy experienced longer survival than the comparators (HR, 0.78 and 0.84, respectively), whereas squamous patients had shorter survival (HR, 1.56 and 1.23, respectively). Whereas the efficacy of pemetrexed regimens differed according to histology, it did not differ for docetaxel or for cisplatin plus gemcitabine. Pemetrexed was well tolerated across histologic groups.
Conclusions.
The consistency of these results across studies confirms the predictive effect of histology for pemetrexed and the survival advantage for pemetrexed in patients with nonsquamous histology. These analyses suggest pemetrexed should not be recommended for the treatment of squamous cell carcinoma, but, because of efficacy and safety advantages, pemetrexed may be preferable to other agents for treatment of patients with nonsquamous NSCLC
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