La formulació magistral i els receptaris en el temps del modernisme

La gran renovació de la farmacoteràpia catalana de fa cent anys i els interrogants que plantej

A practical approach to perform the isotropy test for extremity dosemeters

The requirements for determining extremity dosemeter performance have evolved over the past decade. In 2010, the Spanish Nuclear Safety Council (CSN) adopted a national protocol with performance requirements based on ISO 12794. Because of the lack of symmetry of ISO 4037-3 calibration phantoms, the isotropy test set up in the sagittal plane presented several challenges both for individual monitoring services and for calibration labs. This article proposes and validates a practical approach to reduce the number of irradiations. Results show that wrist and ring dosemeters in this study meet the ISO 12794 requirements for the isotropy test. However, additional studies would be needed to verify the newer IEC 62387 Standard.Postprint (author's final draft

Air kerma to H-P(3) conversion coefficients for IEC 61267 RQR X-RAY radiation qualities: application to dose monitoring of the lens of the eye in medical diagnostics

Recent studies highlight the fact that the new eye lens dose limit can be exceeded in interventional radiology procedures and that eye lens monitoring could be required for these workers. The recommended operational quantity for monitoring of eye lens exposure is the personal dose equivalent at 3 mm depth Hp(3) (ICRU 51). However, there are no available conversion coefficients in international standards, while in the literature coefficients have only been calculated for monoenergetic beams and for ISO 4037-1 X-ray qualities. The aim of this article is to provide air kerma to Hp(3) conversion coefficients for a cylindrical phantom made of ICRU-4 elements tissue-equivalent material for RQR radiation qualities (IEC-61267) from 40 to 120 kV and for angles of incidence from 0 to 180°, which are characteristic of medical workplace. Analytic calculations using interpolation techniques and Monte Carlo modelling have been compared.Postprint (author's final draft

Oramed: optimization of radiation protection of medical staff

Postprint (published version

Need for harmonisation of extremity dose monitoring in nuclear medicine: Results of a survey amongst national dose registries in Europe

Staff handling radiopharmaceuticals in nuclear medicine (NM) may receive significant extremity doses. Over the last decade in particular there has been an increase in NM procedures and new radiopharmaceuticals have been introduced. However, literature provides limited recent data on the exposure of the extremities. In addition, proper assessment of the equivalent dose to the skin can be difficult when applied to the fingertips. In order to gain insight in the actual exposure and to find out how European countries are dealing with monitoring of the extremities, a survey was performed amongst European regulatory authorities. The questions covered general aspects of the national dose registries (NDRs), the measured extremity doses and the practice of the monitoring of workers. The survey shows that extremity dosimetry is performed for about 25%–50% of the monitored workers in NM. Also, the recorded extremity doses in the NDRs are low (mean values 5–29 mSv yr-1) compared to the dose limit. Despite the recommendations that have been published in the last 10 years, few countries provide guidance on the wearing position of extremity dosemeters and the correction factor to estimate the maximum equivalent skin dose from the measured dose. This may lead to an underestimation of the maximum skin dose. Thermoluminescence ring dosemeters are widely used, but wrist dosemeters are also very common, even though the correlation of the measurement with the maximum skin dose is worse than for ring dosemeters. Furthermore, not all countries had a central registration of the extremity dose at the time the survey was performed.Peer ReviewedObjectius de Desenvolupament Sostenible::3 - Salut i BenestarPostprint (published version

The influence of operator position, height and body orientation on eye lens dose in interventional radiology and cardiology: Monte Carlo simulations versus realistic clinical measurements

Objective:This paper aims to provide some practical recommendations to reduce eye lens dose for work-ers exposed to X-rays in interventional cardiology and radiology and also to propose an eye lens correc-tion factor when lead glasses are used.Methods:Monte Carlo simulations are used to study the variation of eye lens exposure with operatorposition, height and body orientation with respect to the patient and the X-ray tube. The paper also looksinto the efficiency of wraparound lead glasses using simulations. Computation results are compared withexperimental measurements performed in Spanish hospitals using eye lens dosemeters as well as withdata from available literature.Results:Simulations showed that left eye exposure is generally higher than the right eye, when the oper-ator stands on the right side of the patient. Operator height can induce a strong dose decrease by up to afactor of 2 for the left eye for 10-cm-taller operators. Body rotation of the operator away from the tube by45°–60°reduces eye exposure by a factor of 2. The calculation-based correction factor of 0.3 for wrap-around type lead glasses was found to agree reasonably well with experimental data.Conclusions:Simple precautions, such as the positioning of the image screen away from the X-ray source,lead to a significant reduction of the eye lens dose. Measurements and simulations performed in thiswork also show that a general eye lens correction factor of 0.5 can be used when lead glasses are wornregardless of operator position, height and body orientation.Postprint (author's final draft

Report of IRPA task group on the impact of the eye lens dose limits

In 2012 IRPA established a task group (TG) to identify key issues in the implementation of the revised eye lens dose limit. The TG reported its conclusions in 2013. In January 2015, IRPA asked the TG to review progress with the implementation of the recommendations from the early report and to collate current practitioner experience. This report presents the results of a survey on the view of the IRPA professionals on the new limit to the lens of the eye and on the wider issue of tissue reactions. Recommendations derived from the survey are presented. This report was approved by IRPA Executive Council on 31 January 2017

Sistema tutelar : un cuento sólo apto para menores

Fil: Freedman, Diego. Universidad de Buenos Aires. Facultad de Derecho. Buenos Aires, ArgentinaFil: Ginjaume, María Alicia. Universidad de Buenos Aires. Facultad de Derecho. Buenos Aires, Argentin