Effects of Methyl Jasmonate and Nano-Methyl Jasmonate Treatments on Monastrell Wine Volatile Composition

This work has been supported by funding provided by the Spanish MCIN/AEI/10.13039/501100011033 and "ERDF, A way of making Europe" through the projects NanoVIT (RTI-2018-095794-B-C21 and RTI-2018-095794-A-C22), and by the Junta de Andalucia with the project NanoFERTi (P18-TP-969). GBRR also acknowledges Junta de Andalucia for her postdoctoral contract within the PAIDI 2020 program (DOC_01383).The application of methyl jasmonate (MeJ) as an elicitor to enhance secondary metabolites in grapes and wines has been studied, but there is little information about its use in conjunction with nanotechnology and no information about its effects on wine volatile compounds. This led us to study the impact of nanoparticles doped with MeJ (Nano-MeJ, 1mM MeJ) on the volatile composition of Monastrell wines over three seasons, compared with the application of MeJ in a conventional way (10 mM MeJ). The results showed how both treatments enhanced fruity esters in wines regardless of the vintage year, although the increase was more evident when grapes were less ripe. These treatments also achieved these results in 2019 in the cases of 1-propanol, ß-phenyl-ethanol, and methionol, in 2020 in the cases of hexanol and methionol, and in 2021, but only in the case of hexanol. On the other hand, MeJ treatment also increased the terpene fraction, whereas Nano-MeJ, at the applied concentration, did not increase it in any of the seasons. In summary, although not all families of volatile compounds were increased by Nano-MeJ, the Nano-MeJ treatment generally increased the volatile composition to an extent similar to that obtained with MeJ used in a conventional way, but at a 10 times lower dose. Therefore, the use of nanotechnology could be a good option for improving the quality of wines from an aromatic point of view, while reducing the necessary dosage of agrochemicals, in line with more sustainable agricultural practices.Junta de Andalucia P18-TP-969 DOC_01383Spanish MCIN/AEI"ERDF, A way of making Europe" through the projects NanoVIT RTI-2018-095794-B-C21 RTI-2018-095794-A-C2

Relevancia de la información recuperada y utilizada desde el punto de vista del usuario de la Biblioteca Agropecuaria de la Universidad Nacional del Nordeste (Corrientes, Argentina)

Se aborda el nivel de relevancia, desde la perspectiva de los usuarios, de la información obtenida para su uso final de la Biblioteca Agropecuaria (BAUNNE) de la Universidad Nacional del Nordeste de la República Argentina. El estudio se centra en el análisis de la relevancia de los documentos obtenidos y utilizados para distintos fines en función de distintas variables como su utilidad, originalidad, especificidad o precisión, claridad, autoridad y actualidad. Para determinar las relaciones entre las variables, se utilizó el Coeficiente de Correlación de Spearman. Los colectivos de usuarios que se estudian en el presente trabajo corresponden a los alumnos de grado, a los alumnos de posgrado de las maestrías, a los doctorandos de las distintas carreras y a los docentes e investigadores y usuarios externos a BAUNNE. Se muestra también la importancia que tiene cada uno de los criterios en la relevancia general dada por el usuario. Se cree necesario contar con una conexión remota adecuada la que permitirá un mejor y más fluído acceso virtual y optimizará el servicio en línea ofrecido por la biblioteca. Asimismo, resulta necesaria una más intensa instrucción del usuario en el uso de los recursos de la biblioteca.In the traditional evaluation of information-retrieval systems, the relevance of a document is determined on a graded scale. At present, relevance is judged from the user’s perspective. In this paper, the relevance is measured on documents that are used for any academic purpose by the users of the Agronomy and Veterinary Library of the Northeastern National University (Corrientes, Argentina). Users are specialized in both fields. We will focus on the relevance analysis of the documents obtained and used for different purposes according to their usefulness, originality, accuracy, clarity, authority, and updatedness. Spearman Coefficient Correlation has been used to determine the relationships between the variables. User types studied in the present paper are graduate and postgraduate students, researchers, academic teachers and external users. This study also shows the importance of each criterion to the general relevance of document from the user standpoint. It is believed that an adequate remote connection would permit a better, fluid access to online information resources and will reinforce the online information services by the library. It is also noted that users need a hardly instruction in the use of the available printed and online resources.Fil: Felquer Acosta, Lucrecia Viviana. Universidad Nacional del Nordeste. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: López Huertas, María José. Universidad de Granada; EspañaFil: Giménez, Laura. Universidad Nacional del Nordeste; Argentin

Management of odontogenic infection of pulpal and periodontal origin

The dental biofilm is a complex bacterial ecosystem that undergoes evolution, maturing and development, and thus leads to odontogenic infection. The infection is normally located in the tissues of the dental organ itself, and follows a chronic course of evolution. However, bacterial pathogens express virulence factors in the biofilm, and this together with changes in host immunity, may cause clinical exacerbations and spread of infection to other areas of the body. Odontogenic infection management should take into consideration the fact that therapeutic success lies in the control of the infectious aetiologic agent, using mechanical-surgical debridement and/or antimicrobial therapy. Debridement techniques have a fundamentally quantitative effect (by reducing the size of the inoculum) and therefore if these techniques are used alone to control infection, despite an initial clinical improvement that is sometimes prematurely considered as therapeutic success, odontopathogens may persist and the process may recur or become chronic. Microbiological examination may be helpful in defining therapeutic success in a more reliable way, it could define the prognosis of recurrence more precisely, and could enable the most appropriate antibiotic to be selected, thus increasing therapeutic efficacy. Antimicrobial therapy brings about a quantitative and qualitative change in the bacterial composition of the biofilm, in addition to being able to act on sites that are inaccessible through mechanical debridement. However, incorrect antimicrobial use can lead to a selection of resistant bacterial species in the biofilm, in addition to side effects and ecological alterations in the host. In order to minimise this risk, and obtain maximum antimicrobial effect, we need to know in which clinical situations their use is indicated, and the efficacy of different antibiotics with regard to bacteria isolated in odontogenic infection

La didáctica del patrimonio en internet : análisis de páginas webs elaboradas por centros de interpretación del patrimonio cultural

Ponencia presentada a: Simposio Internacional de Didáctica de las Ciencias Sociales (15º. 2004. Alicante)Esta comunicación se enmarca dentro de un proyecto I+D centrado en las provincias de Huelva, Sevilla y Cádiz. El estudio que aquí se presenta analiza las páginas webs de los museos de estas provincias, con el objetivo de conocer la perspectiva que tienen de la didáctica del patrimonio y cómo pueden apoyar la actividad profesional de maestros y profesores.This paper is included in a research and development project about heritage education in Huelva, Seville and Cadiz. We introduce a study on museums web site in these provinces. We want know what perspective of these centres about heritage education and how assist to

Cornelia de Lange syndrome : a case report

Cornelia de Lange is a genetic syndrome which affects between 1/10.000 and 1/60.000 neonates, but its genetic bases are still not clear. Its principal clinical characteristics are the delay in growth and development, hirsute, structural anomalies in the limbs and distinctive facial characteristic. Dental problems are frequent and include: ogival palate, micrognathia, dental malalignment, delayed teething, microdontic teeth, periodontal disease and dental erosion produced by gastric reflux. Discussed is the case of a 29 year old patient affected by the syndrome in question, which presents the principal clinical characteristics. The patient?s general state of health is acceptable, without cardiac or respiratory alterations. The intraoral exploration shows policaries, periodontal disease, persistence of the temporal teeth and ectopic molars. After completing the necessary pre-operatory preparations, the entire odontological treatment was carried out under general aesthesia, due to the patient?s total lack of collaboration

Cardiotrophin-1 improves kidney preservation, graft function, and survival in transplanted rats

[EN]Background Cold ischemia-reperfusion injury is unavoidable during organ transplantation, and prolonged preservation is associated with poorer function recovery. Cardiotrophin-1 (CT-1) is an IL-6 family cytokine with cytoprotective properties. This preclinical study in rats tested whether CT-1 mitigates cold renal ischemia-reperfusion injury in the context of the transplantation of long-time preserved kidneys. Methods Kidneys were flushed with cold (4 degrees C) University of Wisconsin solution containing 0.2 g/mL CT-1 and stored for several periods of time at 4 degrees C in the same solution. In a second approach, kidneys were first cold-preserved for 6 hours and then were perfused with University of Wisconsin solution containing CT-1 (0, 16, 32, or 64 g/mL) and further cold-preserved. Organ damage markers were measured in the kidneys at the end of the storage period. For renal transplantation, recipient consanguineous Fischer rats underwent bilateral nephrectomy and received a previously cold-preserved (24 hours) kidney as described above. Survival and creatinine clearance were monitored over 30 days. Results Cardiotrophin-1 in perfusion and preservation fluids reduced oxidative stress markers (superoxide anion and inducible nitric oxide synthase), inflammation markers (NF-B and tumor necrosis factor-), and vascular damage (vascular cell adhesion molecule-1) and activated leukemia inhibitory factor receptor and STAT-3 survival signaling. Transplantation of kidneys cold-preserved with CT-1 increased rat survival and renal function (ie, lower plasma creatinine and higher creatinine clearance) and improved kidney damage markers after transplantation (ie, lower superoxide anion, tumor necrosis factor-, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 and higher NF-B). Conclusions Cardiotrophin-1 represents a novel therapeutic strategy to reduce ischemia-reperfusion and cold preservation injury to rescue suboptimal kidneys and, consequently, to improve the clinical outcomes of renal transplantation

AUDIT, AUDIT-C y AR2I para evaluar el Binge Drinking en universitarios españoles

La identificación de los jóvenes que realizan un consumo intensivo de alcohol (CIA) es una prioridad en el ámbito de la prevención e intervención, dadas las consecuencias bio-psico-sociales que genera. Objetivo. Verificar qué versión del AUDIT constituye el instrumento de screening más adecuado en esta población, partiendo de una operacionalización más precisa del CIA. Método. Se ha realizado un muestreo de conveniencia en el que han participado 190 jóvenes consumidores de alcohol entre 18 y 22 años (73.7% mujeres), que cumplimentaron un autoregistro de consumo de alcohol, el AUDIT y AR2I. Resultados. El análisis de conglomerados por sexos muestra 5 grupos de jóvenes CIA, en función de la edad de inicio en el consumo de alcohol y los gramos ingeridos de esta sustancia durante un episodio CIA. De entre las versiones del AUDIT analizadas, la combinación de los ítems 2 y 3 revisados (AR2I) se desmarca como la mejor opción para identificar a este colectivo. Conclusiones. El AR2I resulta la opción más útil, rápida y sencilla de identificación de jóvenes CIA, permitiendo su implementación en contextos como Atención Primaria, Servicios de Urgencias y recursos especializados en prevención de drogas

El uso de los videojuegos en la formación inicial del profesorado de educación infantil para la enseñanza de las ciencias sociales

Ponencia presentada a: Simposio Internacional de Didáctica de las Ciencias Sociales (25º. 2014. Barcelona

From words to action: an activity on ecosystems framed in the school garden

[RESUMEN] El presente trabajo recoge el desarrollo de una propuesta sobre ecosistemas desde su diseño y planificación hasta su aplicación. Dicha propuesta, contextualizada en el huerto escolar, se fundamenta en el desarrollo del pensamiento sistémico de alumnos de 6º de Primaria y surge de la colaboración entre profesores universitarios y una maestra de Primaria. La implementación de secuencias que implican cierto grado de investigación por parte de los alumnos hace que durante el desarrollo de la actividad surjan dilemas por parte de los maestros sobre cómo continuar con lo planificado. Las decisiones tomadas para resolverlos determinan la secuencia llevada a cabo y constituyen nuevas oportunidades de aprendizaje para los estudiantes de primaria, al mismo tiempo que permiten a los maestros y colaboradores reflexionar sobre las decisiones tomadas de cara a futuras programaciones. Finalmente, se discuten los efectos del desarrollo de esta propuesta en la enseñanza y aprendizaje de los ecosistemas y en el pensamiento sistémico de los alumnos{ABSTRACT}This paper narrates the development of a learning sequence about ecosystems, from its planning till it was carried out. The sequence uses the school garden as a resource, it’s focused on the development of system thinking among 6th grade students and it is the result of collaboration between researchers from the University and school teachers. Teaching sequences including some extent of students’ research lead to dilemmas among teachers about how to continue with the programmed plan. Decisions taken to solve them condition the final sequence carried out, constitute new learning opportunities for students, allow teachers to reflect on the decisions taken and should have implications on teachers’ programming. Finally, the effects of the implemented sequence on the students’ system-thinking and on the acquisition of the ideas about ecosystems are discussed

Heritage, education, identity and citizenship. Teachers and textbooks in compulsory education

El patrimonio es un elemento clave dentro de los procesos de enseñanza y aprendizaje, según se ha podido constatar a través de diferentes estudios llevados a cabo desde hace ya más de 20 años. A partir del patrimonio se pueden trabajar contenidos y problemas relevantes para la sociedad y la educación, entre ellos los aspectos relacionados con ámbitos tan complejos como la identidad y la ciudadanía. Desde la perspectiva que se presenta en este trabajo se concibe una visión de la educación patrimonial de carácter complejo e interdisciplinar, conectando las ciencias sociales con las ciencias naturales y experimentales. Es una visión basada en la resolución de problemas socialmente relevantes, en la interacción, la innovación y en la concepción sociocrítica de la educación. El estudio, fundamentado en este planteamiento teórico, combina técnicas cuantitativas y cualitativas desde el paradigma interpretativo. Se diseña una tabla de categorías (elaboradas como una hipótesis de progresión) que permite un análisis riguroso de los datos obtenidos a través de cuestionarios, rejillas de toma de datos y grupos de discusión. La información es aportada por el profesorado y los libros de texto de educación primaria y secundaria de las materias de Ciencias Sociales, Ciencias Naturales, Geografía e Historia, Biología-Geología y Física y Química. Los resultados permiten aproximarnos a la concepción del patrimonio y de su enseñanza y aprendizaje que se aborda en estos niveles y materias de enseñanza. Se ponen de relieve las relaciones del patrimonio con la identidad, así como los obstáculos existentes para trabajar el patrimonio desde una perspectiva educativa, que provocan un predominio de visiones estéticas y temporales, con estrategias metodológicas de carácter tradicional y finalidades académicas y conservacionistas, que se aproximan a las características del segundo nivel de la hipótesis de progresión en el que se basa este trabajo.Heritage is a key element in the teaching and learning process, as has been noted by different studies conducted for 20 years. From heritage we can work relevant contents and problems for society and education, such as identity and citizenship. This paper presents a complex and interdisciplinary vision of heritage education, connecting the social sciences with natural and experimental sciences. It is a vision based on socially relevant solving problems, interaction, innovation and social criticism conception of education. This study presents a methodology that combines quantitative and qualitative techniques, from the interpretive paradigm. A table of categories is designed (developed as a hypothesis progression) which allows a rigorous analysis of data obtained through questionnaires, data collection tables and discussion groups. The information is provided by teachers and textbooks of primary and secondary subjects of Social Sciences, Natural Sciences, Geography and History, Biology- Geology and Physics and Chemistry. The results allow us to approach the concept of heritage and its teaching and learning that work at these levels and subjects. It becomes relevant the relationship between heritage and identity, as well as obstacles to working heritage from an educational perspective, causing a predominance of aesthetic and temporal visions, with methodological strategies of traditional character and academic and conservationists purposes, approaching the second level of progression hypothesis defended in this work