Infectious intestinal disease : do we know it all?

Infectious intestinal disease (IID), with associated high morbidity and considerable mortality worldwide, causes a wide spectrum of illness. This ranges from mild discomfort to illness with severe complications. The economic burden from direct and indirect costs may be high. It is acquired by oral ingestion of micro-organisms which are transmitted from person to person; via food or water or through contact with animals or contaminated objects. Viruses are the commonest cause in developed countries. In Malta, medical practitioners and laboratories are the main source of data on IID. However, under-reporting is a problem. In order to fill in the lacunae in information on the disease burden, population-based-studies are required. Along with other countries, Malta has embarked on a number of studies to describe and quantify under-reporting of IID. This may assist in strengthening the surveillance system which, in combination with other measures, should result in an improvement of the control of IID.peer-reviewe

Laboratory surveillance of communicable diseases : enteric pathogens

Laboratories represent a crucial link in the surveillance chain. Since only a small proportion of cases of enteric infections are asked to submit a stool sample, one needs to assess the practices for testing for enteric pathogens and their notification practices. Five local laboratories participated in this study. This included a description of the laboratory practices; capacity for stool sample analysis; awareness of the notification system and the factors which could improve the system at laboratory level.peer-reviewe

Comparing village characteristics derived from rapid appraisals and household surveys

This paper investigates whether inferences drawn about a population are sensitive to the manner by which those data are obtained. It compares information obtained using participatory appraisal techniques with a survey of households randomly drawn from a locally administered census that had been carefully revised. The community map tends to include household members who do not, in fact, reside in the enumerated locality. By contrast, the revised official census is slightly more likely to exclude household members who actually lived in the surveyed area. Controlling for the survey technique, we find that the revised official census produces higher estimates of average household size and wealth but lower estimates of total village size or wealth, than the community map. Pairwise comparison of the survey techniques, holding the households constant, shows that the community map leads, on average, to higher estimates of household size and lower estimates of wealth.FCND ,Population Statistics. ,Surveys Methodology. ,Mali. ,

The Galactic disk mass-budget : II. Brown dwarf mass-function and density

In this paper, we extend the calculations conducted previously in the stellar regime to determine the brown dwarf IMF in the Galactic disk. We perform Monte Carlo calculations taking into account the brown dwarf formation rate, spatial distribution and binary fraction. Comparison with existing surveys seems to exclude a power-law MF as steep as the one determined in the stellar regime below 1 \msol and tends to favor a more flatish behaviour. Comparison with methane-dwarf detections tends to favor an eventually decreasing form like the lognormal or the more general exponential distributions determined in the previous paper. We calculate predicting brown dwarf counts in near-infrared color diagrams and brown dwarf discovery functions. These calculations yield the presently most accurate determination of the brown dwarf census in the Galactic disk. The brown dwarf number density is comparable to the stellar one, $n_{BD}\simeq n_\star\simeq 0.1$ pc$^{-3}$. The corresponding brown dwarf mass density, however, represents only about 10% of the stellar contribution, i.e. \rho_{BD}\simle 5.0\times 10^{-3} \mvol. Adding up the local stellar density determined previously yields the density of star-like objects, stars and brown dwarfs, in the solar neighborhood \rho_\odot \approx 5.0\times 10^{-2} \mvol.Comment: 39 pages, Latex file, uses aasms4.sty, to be published in ApJ, corrected version with correct figure

Chaining of welding and finish turning simulations for austenitic stainless steel components

The chaining of manufacturing processes is a major issue for industrials who want to understand and control the quality of their products in order to ensure their in-service integrity (surface integrity, residual stresses, microstructure, metallurgical changes, distortions,…). Historically, welding and machining are among the most studied processes and dedicated approaches of simulation have been developed to provide reliable and relevant results in an industrial context with safety requirements. As the simulation of these two processes seems to be at an operationnal level, the virtual chaining of both must now be applied with a lifetime prediction prospect. This paper will first present a robust method to simulate multipass welding processes that has been validated through an international round robin. Then the dedicated “hybrid method”, specifically set up to simulate finish turning, will be subsequently applied to the welding simulation so as to reproduce the final state of the pipe manufacturing and its interaction with previous operations. Final residual stress fields will be presented and compared to intermediary results obtained after welding. The influence of each step on the final results will be highlighted regarding surface integrity and finally ongoing validation works and numerical modeling enhancements will be discussed

Optimal system size for complex dynamics in random neural networks near criticality

In this Letter, we consider a model of dynamical agents coupled through a random connectivity matrix, as introduced in [Sompolinsky et. al, 1988] in the context of random neural networks. It is known that increasing the disorder parameter induces a phase transition leading to chaotic dynamics. We observe and investigate here a novel phenomenon in the subcritical regime : the probability of observing complex dynamics is maximal for an intermediate system size when the disorder is close enough to criticality. We give a more general explanation of this type of system size resonance in the framework of extreme values theory for eigenvalues of random matrices.Comment: 11 pages, 2 figure

The Galactic disk mass function: reconciliation of the HST and nearby determinations

We derive and parametrize the Galactic mass function (MF) below 1 \msol characteristic of both single objects and binary systems. We resolve the long standing discrepancy between the MFs derived from the HST and from the nearby luminosity functions, respectively. We show that this discrepancy stemmed from {\it two} cumulative effects, namely (i) incorrect color-magnitude determined distances, due a substantial fraction of M dwarfs in the HST sample belonging to the metal-depleted, thick-disk population, as corrected recently by Zheng et al. and (ii) unresolved binaries. We show that both the nearby and HST MF for unresolved systems are consistent with a fraction $\sim$50% of M-dwarf binaries, with the mass of both the primaries and the companions originating from the same underlying single MF. This implies that $\sim$30% of M dwarfs should have an M dwarf companion and $\sim$20% should have a brown dwarf companion, in agreement with recent determinations. The present calculations show that the so-called "brown-dwarf desert" should be reinterpreted as a lack of high mass-ratio (m_2/m_1\la 0.1) systems, and does not preclude a substantial fraction of brown dwarfs as companions of M dwarfs or for other brown dwarfs.Comment: 16 pages, Latex file, uses aasms4.sty, to appear in ApJ Letter

Monte Carlo simulations of the screening potential of the Yukawa one-component plasma

A Monte Carlo scheme to sample the screening potential H(r) of Yukawa plasmas notably at short distances is presented. This scheme is based on an importance sampling technique. Comparisons with former results for the Coulombic one-component plasma are given. Our Monte Carlo simulations yield an accurate estimate of H(r) as well for short range and long range interparticle distances.Comment: to be published in Journal of Physics A: Mathematical and Genera

Structure and dynamics of topological defects in a glassy liquid on a negatively curved manifold

We study the low-temperature regime of an atomic liquid on the hyperbolic plane by means of molecular dynamics simulation and we compare the results to a continuum theory of defects in a negatively curved hexagonal background. In agreement with the theory and previous results on positively curved (spherical) surfaces, we find that the atomic configurations consist of isolated defect structures, dubbed "grain boundary scars", that form around an irreducible density of curvature-induced disclinations in an otherwise hexagonal background. We investigate the structure and the dynamics of these grain boundary scars

Constructor subtyping

Constructor subtyping is a form of subtyping in which an inductive type A is viewed as a subtype of another inductive type B if B has more constructors than A. Its (potential) uses include proof assistants and functional programming languages. In this paper, we introduce and study the properties of a simply typed lambda-calculus with record types and datatypes, and which supports record subtyping and constructor subtyping. In the first part of the paper, we show that the calculus is confluent and strongly normalizing. In the second part of the paper, we show that the calculus admits a well-behaved theory of canonical inhabitants, provided one adopts expansive extensionality rules, including eta-expansion, surjective pairing, and a suitable expansion rule for datatypes. Finally, in the third part of the paper, we extend our calculus with unbounded recursion and show that confluence is preserved.(undefined