2,370 research outputs found
An analytical approach to solution of two- point boundary condition problems in optimal guidance Summary report, May 1965 - Apr. 1966
Analytical approaches to path-adaptive guidance functions, circular orbit trajectories, and use of Fortran-compiled program
Statistical analysis on testing of an entangled state based on Poisson distribution framework
A hypothesis testing scheme for entanglement has been formulated based on the
Poisson distribution framework instead of the POVM framework. Three designs
were proposed to test the entangled states in this framework. The designs were
evaluated in terms of the asymptotic variance. It has been shown that the
optimal time allocation between the coincidence and anti-coincidence
measurement bases improves the conventional testing method. The test can be
further improved by optimizing the time allocation between the anti-coincidence
bases.Comment: This paper is an extended version of the theoretical part of v1 of
quant-ph/0603254.quant-ph/0603254 is revised so that it is more familiar to
experimentalist
The Influence of Spatial Resolution on Nonlinear Force-Free Modeling
The nonlinear force-free field (NLFFF) model is often used to describe the
solar coronal magnetic field, however a series of earlier studies revealed
difficulties in the numerical solution of the model in application to
photospheric boundary data. We investigate the sensitivity of the modeling to
the spatial resolution of the boundary data, by applying multiple codes that
numerically solve the NLFFF model to a sequence of vector magnetogram data at
different resolutions, prepared from a single Hinode/SOT-SP scan of NOAA Active
Region 10978 on 2007 December 13. We analyze the resulting energies and
relative magnetic helicities, employ a Helmholtz decomposition to characterize
divergence errors, and quantify changes made by the codes to the vector
magnetogram boundary data in order to be compatible with the force-free model.
This study shows that NLFFF modeling results depend quantitatively on the
spatial resolution of the input boundary data, and that using more highly
resolved boundary data yields more self-consistent results. The free energies
of the resulting solutions generally trend higher with increasing resolution,
while relative magnetic helicity values vary significantly between resolutions
for all methods. All methods require changing the horizontal components, and
for some methods also the vertical components, of the vector magnetogram
boundary field in excess of nominal uncertainties in the data. The solutions
produced by the various methods are significantly different at each resolution
level. We continue to recommend verifying agreement between the modeled field
lines and corresponding coronal loop images before any NLFFF model is used in a
scientific setting.Comment: Accepted to ApJ; comments/corrections to this article are welcome via
e-mail, even after publicatio
How to simulate a quantum computer using negative probabilities
The concept of negative probabilities can be used to decompose the
interaction of two qubits mediated by a quantum controlled-NOT into three
operations that require only classical interactions (that is, local operations
and classical communication) between the qubits. For a single gate, the
probabilities of the three operations are 1, 1, and -1. This decomposition can
be applied in a probabilistic simulation of quantum computation by randomly
choosing one of the three operations for each gate and assigning a negative
statistical weight to the outcomes of sequences with an odd number of negative
probability operations. The exponential speed-up of a quantum computer can then
be evaluated in terms of the increase in the number of sequences needed to
simulate a single operation of the quantum circuit.Comment: 11 pages, including one figure and one table. Full paper version for
publication in Journal of Physics A. Clarifications of basic concepts and
discussions of possible implications have been adde
Schrodinger cats and their power for quantum information processing
We outline a toolbox comprised of passive optical elements, single photon
detection and superpositions of coherent states (Schrodinger cat states). Such
a toolbox is a powerful collection of primitives for quantum information
processing tasks. We illustrate its use by outlining a proposal for universal
quantum computation. We utilize this toolbox for quantum metrology
applications, for instance weak force measurements and precise phase
estimation. We show in both these cases that a sensitivity at the Heisenberg
limit is achievable.Comment: 10 pages, 5 figures; Submitted to a Special Issue of J. Opt. B on
"Fluctuations and Noise in Photonics and Quantum Optics" (Herman Haus
Memorial Issue
Targeting danger molecules in tendinopathy: the HMGB1/TLR4 axis
Objectives: To seek evidence of the danger molecule, high-mobility group protein B1 (HMGB1) expression in human tendinopathy and thereafter, to explore mechanisms where HMGB1 may regulate inflammatory mediators and matrix regulation in human tendinopathy.
Methods: Torn supraspinatus tendon (established pathology) and matched intact subscapularis tendon (representing âearly pathologyâ) biopsies were collected from patients undergoing arthroscopic shoulder surgery. Control samples of subscapularis tendon were collected from patients undergoing arthroscopic stabilisation surgery. Markers of inflammation and HMGB1 were quantified by reverse transcriptase PCR (RT-PCR) and immunohistochemistry. Human tendon-derived primary cells were derived from hamstring tendon tissue obtained during hamstring tendon anterior cruciate ligament reconstruction and used through passage 3. In vitro effects of recombinant HMGB1 on tenocyte matrix and inflammatory potential were measured using quantitative RT-PCR, ELISA and immunohistochemistry staining.
Results: Tendinopathic tissues demonstrated significantly increased levels of the danger molecule HMGB1 compared with control tissues with early tendinopathy tissue showing the greatest expression. The addition of recombinant human HMGB1 to tenocytes led to significant increase in expression of a number of inflammatory mediators, including interleukin 1 beta (IL-1ÎČ), IL-6, IL-33, CCL2 and CXCL12, in vitro. Further analysis demonstrated rhHMGB1 treatment resulted in increased expression of genes involved in matrix remodelling. Significant increases were observed in Col3, Tenascin-C and Decorin. Moreover, blocking HMGB1 signalling via toll-like receptor 4 (TLR4) silencing reversed these key inflammatory and matrix changes.
Conclusion: HMGB1 is present in human tendinopathy and can regulate inflammatory cytokines and matrix changes. We propose HMGB1 as a mediator driving the inflammatory/matrix crosstalk and manipulation of the HMGB1/TLR4 axis may offer novel therapeutic approaches targeting inflammatory mechanisms in the management of human tendon disorders
Miniaturized data loggers and computer programming improve seabird risk and damage assessments for marine oil spills in Atlantic Canada
Obtaining useful information on marine birds that can aid in oil spill (and other hydrocarbon release) risk and damage assessments in offshore environments is challenging. Technological innovations in miniaturization have allowed archival data loggers to be deployed successfully on marine birds vulnerable to hydrocarbons on water. A number of species, including murres (both Common, Uria aalge, and Thick-billed, U. lomvia) have been tracked using geolocation
devices in eastern Canada, increasing our knowledge of the seasonality and colony-specific nature of their susceptibility to oil on water in offshore hydrocarbon production areas and major shipping lanes. Archival data tags are starting to resolve questions around behaviour of vulnerable seabirds at small spatial scales relevant to oil spill impact modelling, specifically to determine the duration and frequency at which birds fly at sea. Advances in data capture methods using voice activated software have eased the burden on seabird observers who are collecting
increasingly more detailed information on seabirds during ship-board and aerial transects. Computer programs that integrate seabird density and bird behaviour have been constructed, all with a goal of creating more credible seabird oil spill risk and damage assessments. In this paper, we discuss how each of these technological and computing innovations can help define critical inputs into seabird risk and damage assessments, and when combined, can provide a more realistic understanding of the impacts to seabirds from any hydrocarbon release
Three-Body Dynamics and Self-Powering of an Electrodynamic Tether in a Plasmasphere
The dynamics of an electrodynamic tether in a three-body gravitational environment are investigated. In the classical two-body scenario the extraction of power is at the expense of orbital kinetic energy. As a result of power extraction, an electrodynamic tether satellite system loses altitude and deorbits. This concept has been proposed and well investigated in the past, for example for orbital debris mitigation and spent stages reentry. On the other hand, in the three-body scenario an electrodynamic tether can be placed in an equilibrium position fixed with respect to the two primary bodies without deorbiting, and at the same time generate power for onboard use. The appearance of new equilibrium positions in the perturbed three-body problem allow this to happen as the electrical power is extracted at the expenses of the plasma corotating with the primary body. Fundamental differences between the classical twobody dynamics and the new phenomena appearing in the circular restricted three-body problem perturbed by the electrodynamic force of the electrodynamic tether are shown in the paper. An interesting application of an electrodynamic tether placed in the Jupiter plasma torus is then considered, in which the electrodynamic tether generates useful electrical power of about 1 kW with a 20-km-long electrodynamic tether from the environmental plasma without losing orbital energy
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