Genome of Alcanivorax sp. 24 : a hydrocarbon degrading bacterium isolated from marine plastic debris

Alcanivorax is an important member of the hydrocarbonoclastic group known for using alkanes and other related compound as their preferred carbon source. Here we report the genomic characteristics of Alcanivorax sp. 24 isolated from plastic marine debris. Its 4,765,873 bp genome, containing 4239 coding sequences, revealed the presence of all genomic features involved in alkane degradation (i.e. two cytochrome P450, three alkane monooxygenases AlkB and two enzymes involved in the degradation of long-chain alkanes AlmA) as well as other relevant enzymes that may play a role in the biodegradation of other polymers such as polyhydroxybutyrate. The genome features and phylogenetic context of these genes provide interesting insight into the lifestyle versatility of Alcanivorax sp. living in the plastisphere of marine plastic debris

Urgent Challenges for Local Public Health Informatics

This editorial highlights the urgent challenges for local public health informatics and provides solutions to face these challenges

Radiometer offsets and count conversion coefficients for the Earth Radiation Budget Experiment (ERBE) spacecraft for the years 1984, 1985, and 1986

A compendium is presented of the ground and inflight scanner and nonscanner offsets and count conversion (gain) coefficients used for the Earth Radiation Budget Experiment (ERBE) production processing of data from the ERBS, NOAA-9, and NOAA-10 satellites for the 1 Nov. 1984 to 31 Dec. 1986

The Society for Industrial and Organizational Psychology’s Guidelines for Education and Training: An Executive Summary of the 2016/2017 Revision

The Society for Industrial and Organizational Psychology (SIOP, Division 14 of the American Psychological Association [APA]) maintains Guidelines for Education and Training to provide guidance for the training of industrial-organizational (I-O) psychologists. The 2016/2017 revision combines separate documents for master’s- and doctoral-level training into one document, because the competencies required for each degree are not very different. Instead, the degrees differ in breadth and depth. The updated Guidelines were approved as APA policy in August 2017. In this article, we briefly review the revision process and highlight the updates made in the latest version of the Guidelines. (PsycINFO Database Record (c) 2018 APA, all rights reserved

Arthropods on Mars?

As presented in this report numerous fossils like forms resembling a variety of marine arthropods including crustaceans, sea spiders, scorpions, arachnids, nematodes, annelids, tube worms, sea snakes, Kimberlla, Namacalathus, Lophotrochozoa, armored trilobites and millipedes have been found in Gale Crater (on Sols 302, 553, 753, 781, 809, 869, 880, 905, 1032), and Meridiani Planum both of which have hosted rivers, lakes, and inland seas. Similar specimens are mixed within a variety of divergent fossillike forms and are also found on distant sediment and mud stone. All specimens are distinct from underlying substrate and there are no obvious patterns or repetitions typically produced by erosion or weathering. Although without extraction and direct examination it is impossible to precisely determine the identity of all these specimens, the same problems bedevil identification of Burgess Shale fossils some of which are presented in this report for comparative analysis. The discoveries presented here and in other reports supports the theory that metazoans and other marine organisms evolved in the lakes, oceans and inland seas of Mars

Effects of Growth Hormone Treatment in Adults with Prader-Willi Syndrome

OBJECTIVE: Since limited data exist on adults with Prader-Willi syndrome (PWS) and growth hormone (GH) treatment, we report our experience on the effects of treatment for one year on body composition, physical activity, strength and energy expenditure, diet, general chemistry and endocrine data with quality of life measures. DESIGN: We studied 11 adults with PWS (6F:5M; average age = 32 yrs) over a 2 year period with GH treatment during the first year only. Electrolytes, IGF-I, glucose, thyroid, insulin, lipids, body composition, physical activity and strength, diet, energy expenditure and quality of life data were collected and analyzed statistically using linear modeling at baseline, at 12 months following GH therapy and at 24 months after treatment cessation for 12 months. RESULTS: Total lean muscle mass was significantly increased (p < 0.05) during GH treatment along with moderate-vigorous physical activity and plasma IGF-I and HDL levels, but returned to near baseline after treatment. Percent body fat decreased during the 12 months of GH treatment but increased after treatment. CONCLUSIONS: Previously reported beneficial effects of GH treatment in children with PWS were found in our adults regarding body composition, physical activity and plasma HDL and IGF-I levels. Several beneficial effects diminished to near baseline after cessation of GH treatment for 12 months supporting the continuation of treatment in PWS into adulthood and possibly adults not previously treated during childhood

Radiometer offsets and count conversion coefficients for the Earth Radiation Budget Experiment (ERBE) spacecraft for the years 1987, 1988, and 1989

This document contains a compendium of the ground and in-flight scanner and non-scanner offsets and count conversion (gain) coefficients used for the Earth Radiation Budget Experiment (ERBE) production processing of data from the ERBS satellite for the period from 1 January 1987 to 31 December 1989; for the NOAA-9 satellite, for the month of January 1987; and for the NOAA-10 satellite, for the period from 1 January 1987 to 31 May 1989

The Heavy Element Enrichment of Lyman alpha Clouds in the Virgo Supercluster

Using high S/N STIS echelle spectra (FWHM=7 km/s) of 3C 273, we constrain the metallicities of two Lya clouds in the vicinity of the Virgo cluster. We detect C II, Si II, and Si III absorption lines in the Lya absorber at z = 0.00530. Previous observations with FUSE have revealed Ly beta - Ly theta lines at this redshift, thereby accurately constraining N(H I). We model the ionization of the gas and derive [C/H] = -1.2^{+0.3}_{-0.2}, [Si/C] = 0.2+/-0.1, and log n_{H} = -2.8+/-0.3. The model implies a small absorber thickness, ~70 pc, and thermal pressure p/k ~ 40 cm^{-3} K. It is most likely that the absorber is pressure confined by an external medium because gravitational confinement would require a very high ratio of dark matter to baryonic matter. Based on Milky Way sight lines in which carbon and silicon abundances have been reliably measured in the same interstellar cloud (including new measurements presented herein), we argue that the overabundance of Si relative to C is not due to dust depletion. Instead, this probably indicates that the gas has been predominately enriched by Type II supernovae. Such enrichment is most plausibly provided by an unbound galactic wind, given the absence of galaxies within a projected distance of 100 kpc and the presence of galaxies capable of driving a wind at larger distances. We also constrain the metallicity and physical conditions of the Virgo absorber at z = 0.00337 based on detections of O VI and H I and an upper limit on C IV. If this absorber is collisionally ionized, the O VI/C IV limit requires T > 10^{5.3} K. For either collisional ionization or photoionization, we find that [O/H] > -2.0 at z = 0.00337.Comment: Final Ap.J. versio

Increased Excitability Induced in the Primary Motor Cortex by Transcranial Ultrasound Stimulation

Background: Transcranial Ultrasound Stimulation (tUS) is an emerging technique that uses ultrasonic waves to noninvasively modulate brain activity. As with other forms of non-invasive brain stimulation (NIBS), tUS may be useful for altering cortical excitability and neuroplasticity for a variety of research and clinical applications. The effects of tUS on cortical excitability are still unclear, and further complications arise from the wide parameter space offered by various types of devices, transducer arrangements, and stimulation protocols. Diagnostic ultrasound imaging devices are safe, commonly available systems that may be useful for tUS. However, the feasibility of modifying brain activity with diagnostic tUS is currently unknown. Objective: We aimed to examine the effects of a commercial diagnostic tUS device using an imaging protocol on cortical excitability. We hypothesized that imaging tUS applied to motor cortex could induce changes in cortical excitability as measured using a transcranial magnetic stimulation (TMS) motor evoked potential (MEP) paradigm. Methods: Forty-three subjects were assigned to receive either verum (n = 21) or sham (n = 22) diagnostic tUS in a single-blind design. Baseline motor cortex excitability was measured using MEPs elicited by TMS. Diagnostic tUS was subsequently administered to the same cortical area for 2 min, immediately followed by repeated post-stimulation MEPs recorded up to 16 min post-stimulation. Results: Verum tUS increased excitability in the motor cortex (from baseline) by 33.7% immediately following tUS (p = 0.009), and 32.4% (p = 0.047) 6 min later, with excitability no longer significantly different from baseline by 11 min post-stimulation. By contrast, subjects receiving sham tUS showed no significant changes in MEP amplitude. Conclusion: These findings demonstrate that tUS delivered via a commercially available diagnostic imaging ultrasound system transiently increases excitability in the motor cortex as measured by MEPs. Diagnostic tUS devices are currently used for internal imaging in many health care settings, and the present results suggest that these same devices may also offer a promising tool for noninvasively modulating activity in the central nervous system. Further studies exploring the use of diagnostic imaging devices for neuromodulation are warranted