Meningkatkan Kemampuan Pemahaman Matematis Siswa Melalui Problem Posing

Penelitian ini ditujukan untuk melihat adanya peningkatan kemampuan pemahaan matematis siswa yang menggunakan model pembelajaran problem posing, dimana pada model pembelajaran ini siswa membuat soal sendiri yang sebelumnya harus menguasai dan memahami terhadap materi yang akan dipertanyakan pada soal. Subjek penelitian ini adalah siswa SMP Negeri 3 Sumberjaya Kabupaten Majalengka dengan menggunakan metode penelitian tindakan kelas. Dalam penelitian ini instrumen atau alat yang digunakan untuk mengumpulkan data adalah; (a) Seperangkat Soal, (b) Angket, (c) Pedoman Kriteria Ketuntasan Minimal. Untuk melihat hasil dari penelitian, penulis menganalisis data hasil pretes dan postes siswa diperoleh rata-rata pretes adalah 44,86 dan rata-rata pada postes 74,14. Hal ini menunjukan bahwa terdapat peningkatan pemahaman matematis siswa melalui pendekatan problem posing dalam penyelesaian soal cerita lebih efektif. Hal ini dibuktikan dengan gain ternormalisasi yang menunjukan bahwa rata-rata gain ternormalisasi ada peningkatan dari siklus I ke siklus II, siklus II ke siklus III dan pretes ke postes. Hal serupa juga dibuktikan dengan uji signifikansi.Kata Kunci: problem posing, pemahaman matemati

INDEKS LITERASI WAKAF GENERASI MILENIAL

Indeks literasi wakaf sebagai alat ukur yang digunakan untuk mengetahui pemahaman masyarakat tentang wakaf secara komprehensif dan akurat. Adanya gagasan indeks literasi wakaf memiliki peran penting bagi para peneliti untuk memiliki alat ukur dalam menilai tingkat pemahaman wakaf di masyarakat. Hasil pengukuran tingkat pemahaman generasi milenial wakaf yang diukur menggunakan alat ukur indeks literasi wakaf, ditemukan bahwa generasi milenial di Jakarta memiliki skor 36,71% (kategori rendah) dari 100 responden survei di Provinsi DKI Jakarta

TEKNIK DUTCH ANGLE SEBAGAI PENGUAT UNSUR DRAMATIK PADA FILM DANUR: I CAN SEE GHOSTS

ABSTRAK TEKNIK DUTCH ANGLE SEBAGAI PENGUAT UNSUR DRAMATIK PADA FILM DANUR: I CAN SEE GHOSTS (Ghanny Rasyidi Utama, 2018, hal. Xi – 81) Skripsi S-1 Prodi Televisi dan Film, Fakultas Seni Rupa dan Desain, Institut Seni Indonesia Surakarta. Film Danur: I Can See Ghosts menjadi salah satu film Horor di Indonesia yang mendapatkan rekor MURI (Musium Rekor Indonesia) sebagai film horor pertama dengan jumlah penonton terbanyak dalam enam hari. Film ini memiliki sisi menarik pada segi teknik pengambilan gambar (Sinematografi). Teknik pengambilan gambar yaitu teknik Dutch Angle. Penelitian dilakukan untuk mengetahui teknik Dutch Angle yang memperkuat unsur dramatik(konflik, susspense/tegang, takut, ngeri, seram, surprise, susah, senang, sedih). Metode penelitian menggunakan penelitian kualitatif, data yang dianalisis berupa potongan-potongan adegan pada film tersebut. Analisis data dengan reduksi data, model data serta penarikan kesimpulan. Hasil penelitian menunjukkan bahwa teknik dutch angle dalam film Danur:I Can See Ghosts mampu memperkuat unsur dramatik dengan tingkat kemunculan yang berbeda. Unsur dramatik seram lebih sering muncul dalam film ini. Pengambilan gambar teknik dutch angle muncul di adegan-adegan menyeramkan pada film Danur: I Can See Ghosts. Kata Kunci : Teknik Dutch angle, Unsur Dramatik, Film Danur: I Can See Ghost

INFORMASI TUJUAN WISATA DI KOTA BLITAR

Pariwisata adalah hal yang paling bernilai bagi suatu daerah tertentu untuk meningkatkan potensi Anggaran Pendapatan Daerah (APD). Dengan adanya tujuan wisata di suatu daerah tertentu akan dapat meningkatkan kesejahteraan masyarakatnya. Salah satunya adalah kota Blitar yang memiliki banyak sekali potensi untuk pariwisatanya, jika didukung dengan perkembangan sarana dan prasarana lebih jauh maka akan dapat meningkatkan potensi pariwisata di kota Blitar. Penggunaan Teknologi Informasi (TI) dapat digunakan untuk mendukung dan memajukan potensi pariwisata, sehingga pariwisata dapat lebih banyak dikenal oleh turis yang berkunjung ke kota Blitar. Dari hal ini maka dibuatlah mobile app yang mendukung informasi tentang pariwisata di kota Blitar. Aplikasi yang dikembangkan menggunakan platform Android. Dengan sistem distribusi secara open source yang digunakan dapat memungkinkan para pengembang untuk menciptakan berbagai aplikasi menarik yang dapat dinikmati oleh para pengguna, seperti game, chatting dan banyak lagi. Salah satunya adalah pengembangan aplikasi tur gouide di kota Blitar yang dapat membantu orang memberikan informasi pada pariwisata jarang dikunjungi di Blitar. Tujuan dari aplikasi program ini untuk membantu orang mengenal lebih dekat tempat pariwisata yang ada Blitar. Aplikasi tour guide Blitar berbasis kota android memberikan informasi pariwisata yang ada Blitar, sejarah Blitar, restoran, hotel, transportasi di kota dan agenda acara tahunan Blitar yang ada di kota Blitar. Di tempat manapun juga dengan rute google maps menurut situs yang akan dikunjungi

Pengaruh Harga, Kualitas Produk, dan Kualitas Pelayanan terhadap Kepuasan Pelanggan SuperIndo Adi Sucipto Solo

The purpose of this study was to analyze the effect of price on customer satisfaction of Superindo Adisucipto Solo. To analyze the effect of product quality on customer satisfaction of Superindo Adisucipto Solo. To analyze the effect of service quality on customer satisfaction of Superindo Adisucipto Solo. The population of this study is customers of Superindo Adisucipto Solo. In this study using a non-probability sampling approach with purposive sampling technique. Samples in this study were 75 respondents. Based on the result of this study indicate that there is a positive and significant price effect on customer satisfaction, so the first hypothesis states that price have positive and significant effect on customer satisfaction proven truth. There is a positive and significant effect of product quality on customer satisfaction, so the second hypothesis states that product quality have positive and significant effect on customer satisfaction is proven to be true. There is a positive and significant effect of service quality on customer satisfaction, so the second hypothesis states that service quality have positive and significant effect on customer satisfaction is proven to be true. There is positive and significant joint influence on price, product quality, and service quality on customer satisfaction. Keywords: Price, Product Quality, Service Quality, and Customer Satisfactio

TEKNOLOGI PENGOLAHAN PANGAN ALTERNATIF, TINUTUAN INSTAN SOLUSI STUNTING DAN PEMASTIAN MUTU KADAR GIZINYA

ABSTRACTTinutuan or Manado porridge is a typical food from Manado, North Sulawesi made from various kinds of vegetables. Generally, Manado tinutuan or porridge is served immediately after cooking, but in this study it was made in an instant form so that it was easy and practical. The purpose of the study was to find out how to make instant tinutuan and analyze the nutritional levels contained in instant tinutuan in an effort to overcome the problem of stunting. The method of making instant tinutuan using the extraction method. In this study, carbohydrates, fats, and proteins were tested. The results showed that tinutuan contained carbohydrates, fat, and protein with samples of rice, garlic, spinach, basil, onion, pumpkin, cassava, and corn. Carbohydrate test results obtained per 100 grams, 0.570; 0.828; 0.160; 0.779; 0.800; 4,335; 0.524; 5,253. Fat test results obtained per 100 grams of sample, 27.7%; 5.6%; 5.8%; 21.4%; 4.9%; 3.8%; 7.4%; 17.6%. The results of protein testing of samples obtained per gram of sample, 4.3%; 3.8%; 47.1%; 10%; 7.4%; 17.1%; 7%; 8.5%. Based on the results of the study, tinutuan contains high levels of nutrients (carbohydrates, fat, and protein) and can be recommended to overcome the problem of stunting. Keywords: Instant Tinutuan, Stunting, Nutritional Levels ABSTRAKTinutuan atau bubur Manado adalah makanan khas Manado, Sulawesi Utara yang terbuat dari berbagai macam sayuran. Umumnya tinutuan atau bubur Manado langsung disajikan setelah dimasak, tetapi pada penelitian ini dibuat dalam bentuk instan sehingga mudah dan praktis. Tujuan penelitian ialah mengetahui cara pembuatan tinutuan instan dan menganalisis kadar gizi yang terkandung dalam tinutuan instan sebagai upaya dalam mengatasi masalah stunting. Metode pembuatan tinutuan instan menggunakan metode ekstraksi. Pada penelitian ini dilakukan pengujian karbohidrat, lemak, dan protein. Hasil penelitian menunujukkan bahwa tinutuan mengandung karbohidrat, lemak, dan protein dengan sampel beras, bawang putih, bayam, kemangi, bawang merah, labu, singkong, dan jagung. Hasil pengujian karbohidrat yang didapat per 100 gram, 0,570; 0,828; 0,160; 0,779; 0,800; 4,335; 0,524; 5,253. Hasil pengujian lemak yang didapat per 100 gram sampel, 27,7%; 5,6%; 5,8%; 21,4%; 4,9%; 3,8%; 7,4%; 17,6%. Hasil pengujian protein sampel yang didapat per gram sampel, 4,3%; 3,8%; 47,1%; 10%; 7,4%; 17,1%; 7%; 8,5%. Berdasarkan hasil penelitian, tinutuan mengandung kadar gizi (karbohidrat, lemak, dan protein) dan dapat disarankan untuk mengatasi masalah stunting. Kata Kunci: Tinutuan Instan, Stunting, Kadar Giz

The IGSF1 deficiency syndrome may present with normal free T4 levels, severe obesity, or premature testicular growth

Our objective was to further expand the spectrum of clinical characteristics of the IGSF1 deficiency syndrome in affected males. These characteristic include almost universal congenital central hypothyroidism (CeH) with disharmonious pubertal development (normally timed testicular growth, but delayed rise of serum testosterone), macroorchidism, increased body mass index (BMI), and decreased attentional control. In addition, a subset of patients show prolactin deficiency, transient partial growth hormone deficiency in childhood and increased growth hormone secretion in adulthood. We present a family in which the proband was diagnosed with CeH and low serum prolactin. Severe weight gain started at two years old, with a BMI of 42.3 at 13.9 years. Testicular enlargement (5-6 mL, 3.8-4.3 standard deviation score) started aged three years. A pathogenic variant was found in the IGSF1 gene: c.3411_3412del, p.(Tyr1137*). His brother was referred for short stature at age 13 years and was diagnosed with CeH, normal serum prolactin and IGF-1, and disharmonious puberty. In four male relatives (the proband's brother and three cousins) with the variant (one adult), free thyroxine (fT4) was below the lower limit of the reference range in two, and just above this limit in the other two. Three were overweight or obese, adolescents had disharmonious pubertal development and the adult had profound macroorchidism. In conclusion, male hemizygous carriers of a pathogenic IGSF1 variant can present with fT4 concentration above the lower limit of the reference range while severe early onset obesity or premature testicular growth are part of the phenotypic spectrum.Genetics of disease, diagnosis and treatmen

Tropism and neutralisation studies on bat influenza H17N10

The diversity of subtypes within Influenza A recently expanded with identification of H17N10 and H18N11 from bats. To study the tropism and zoonotic potential of these viruses, we successfully produced lentiviral pseudotypes bearing haemagglutinin H17 and neuraminidase N10. We investigated a range of cell lines from different species for their susceptibility to infection by these pseudotypes and show that a number of human haematopoietic cancer cell lines and the canine kidney MDCK II (but not MDCK I) cells are susceptible. Using microarrays and qRT-PCR we show that the dog leukocyte antigen DLA-DRA mRNA is over expressed in late passaged parental MDCK and commercial MDCK II cells, compared to early passaged parental MDCK and MDCK I cells, respectively. The human orthologue HLA-DRA encodes the alpha subunit of the MHC class II HLA-DR antigen-binding heterodimer. Small interfering RNA- or neutralizing antibody-targeting HLA-DRA, drastically reduced the susceptibility of Raji B cells to H17-PV. Conversely, over expression of HLA-DRA and its paralogue HLA-DRB1 on the surface of unsusceptible HEK293T/17 cells conferred susceptibility to H17-PV. The identification of HLA-DR as an H17N10 entry mediator will contribute to understanding the tropism of the virus and help to elucidate its zoonotic transmission. We also show that H17 pseudotypes can be efficiently neutralised by the broadly-neutralizing HA2 stalk monoclonal antibodies CR9114 and FI6. The lentiviral pseudotype system is a useful research tool, amenable for investigation of bat influenza tropism, restriction and pandemic preparedness, without safety issues of producing a replication-competent virus, to which the human population is naïve

Carbonic anhydrase enzymes regulate mast cell–mediated inflammation

Type 2 cytokine responses are necessary for the development of protective immunity to helminth parasites but also cause the inflammation associated with allergies and asthma. Recent studies have found that peripheral hematopoietic progenitor cells contribute to type 2 cytokine–mediated inflammation through their enhanced ability to develop into mast cells. In this study, we show that carbonic anhydrase (Car) enzymes are up-regulated in type 2–associated progenitor cells and demonstrate that Car enzyme inhibition is sufficient to prevent mouse mast cell responses and inflammation after Trichinella spiralis infection or the induction of food allergy–like disease. Further, we used CRISPR/Cas9 technology and illustrate that genetically editing Car1 is sufficient to selectively reduce mast cell development. Finally, we demonstrate that Car enzymes can be targeted to prevent human mast cell development. Collectively, these experiments identify a previously unrecognized role for Car enzymes in regulating mast cell lineage commitment and suggest that Car enzyme inhibitors may possess therapeutic potential that can be used to treat mast cell–mediated inflammation

The Capacity of Mycobacterium tuberculosis To Survive Iron Starvation Might Enable It To Persist in Iron-Deprived Microenvironments of Human Granulomas

ABSTRACT This study was conducted to investigate the role of iron deprivation in the persistence of Mycobacterium tuberculosis. We present evidence of iron restriction in human necrotic granulomas and demonstrate that under iron starvation M. tuberculosis persists, refractive to antibiotics and capable of restarting replication when iron is made available. Transcriptomics and metabolomic analyses indicated that the persistence of M. tuberculosis under iron starvation is dependent on strict control of endogenous Fe utilization and is associated with upregulation of pathogenicity and intrinsic antibiotic resistance determinants. M. tuberculosis mutants compromised in their ability to survive Fe starvation were identified. The findings of this study advance the understanding of the physiological settings that may underpin the chronicity of human tuberculosis (TB) and are relevant to the design of effective antitubercular therapies