98 research outputs found

    Statistical Lineament Analysis in South Greenland Based on Landsat Imagery

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    Grundtvig och Geijer - Två nordiska giganter

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    Grundtvig and Geijer - Two nordic giantsReviewed by Gert Nilsso

    Tord Ehnevid in memoriam

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    In Memory of Tord Ehnevid, 1922 - 2000By Gert NilssonDoctor of divinity Gert Nilsson’s obituary of the Swedish Grundtvig scholar Tord Ehnevid begins with a presentation of Ehnevid’s background and his point of departure. Ehnevid was bom into an evironment characterized partly by revivalist piety, partly by Swedish State Church tradition, a fact which came to influence his later research. Tord Ehnevid studied theology at Lund and took holy orders in 1947. After working as a clergyman for some years, continuing his studies at the same time, he became a curate in Trelleborg in 1958, and subsequently worked as a grammar school teacher at Söderslatt Grammar School until his retirement.In 1959 his doctoral thesis Församlingsetik Studier over Grundtvig, Morten Pontoppidan och Einar Billing was published. The thesis focuses on the national church and its congregational ethics, comparing important positions in Danish and Swedish theology. In the following years Ehnevid published a number of writings in Grundtvig Studier, such as The dominant Peoples in History according to Grundtvig and Hegel in 1973. In »Vad Sandhed er skal tiden vise«, 1998, Ehnevid deals with the concept of truth, time and ethics in Grundtvig’s works.From the early 1970’s Tord Ehnevid was a member of the Grundtvig society committee. And as late as 1998 he participated in the annual meeting in Århus. With Tord Ehnevid’s decease, a good clergyman, a competent pedagogue and an original interpreter of Danish and Swedish theology has passed away. His ideas and writings will live.

    Rehabilitation provided to patients with rheumatoid arthritis: A comparison of three different rheumatology clinics in Austria, Sweden and the UK from the perspectives of patients and health professionals

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    © 2015 The Authors. © 2015 Foundation of Rehabilitation Information. Objective: To explore patients' and health professionals' views of outpatient rehabilitation services for patients with rheumatoid arthritis in 3 different rheumatology sites across Europe. Methods: A qualitative multi-method study was conducted with patients and health professionals in Vienna (Austria), Gothenburg (Sweden) and Leeds (UK). Data collection was carried out during focus groups with patients and health professionals. Patients' hospital records were integrated into the analysis. Data were analysed for site and findings were compared across sites. Results: A total of 20 patients and 20 health professionals participated in 12 focus groups. Although the 3 sites were all publicly funded university clinics, there were differences between sites regarding the structure and content of rehabilitation services. The themes that emerged in the focus groups were: referrals; continuity in rehabilitation; information provided to patients; patients' organizations; documentation and communication amongst health professionals; interface between primary and specialist care; and prescription practices. Most themes were addressed at all 3 sites, but there were variations in the specifics within themes. Conclusion: Integration of patients' and health professionals' views on how rehabilitation services are coordinated and how (parts of) processes are set up elsewhere provide valuable information for the further optimization of rehabilitation services

    Virtual Drive Testing Over-The-Air for Vehicular Communications

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    Multiple-input multiple-output (MIMO) over-the-air (OTA) testing is a standardized procedure to evaluate the performance of MIMO-capable devices such as mobile phones and laptops. With the growth of the vehicle-to-everything (V2X) service, the need for vehicular communication testing is expected to increase significantly. The so-called multi-probe anechoic chamber (MPAC) setup is standardized for MIMO OTA testing. Typically, a test zone of 0.85 wavelength in diameter can be achieved with an 8-probe MPAC setup, which can encompass device-under-test (DUT) of small form factors. However, a test zone of this size may not be large enough to encompass DUTs such as cars. In this article, the sufficient number of OTA probes for the MPAC setup for car testing is investigated with respect to the emulation accuracy. Our investigation shows that the effective antenna distance of the DUT is more critical than its physical dimensions to determine the required number of OTA probes. In addition, throughput measurements are performed under the standard SCME UMa and UMi channel models with the 8-probe MPAC setup and the wireless cable setup, i.e. another standardized testing setup. The results show reasonably good agreement between the two setups for MIMO OTA testing with cars under the standard channel models

    Photocross-linking of nascent chains to the STT3 subunit of the oligosaccharyltransferase complex

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    In eukaryotic cells, polypeptides are N glycosylated after passing through the membrane of the ER into the ER lumen. This modification is effected cotranslationally by the multimeric oligosaccharyltransferase (OST) enzyme. Here, we report the first cross-linking of an OST subunit to a nascent chain that is undergoing translocation through, or integration into, the ER membrane. A photoreactive probe was incorporated into a nascent chain using a modified Lys-tRNA and was positioned in a cryptic glycosylation site (-Q-K-T- instead of -N-K-T-) in the nascent chain. When translocation intermediates with nascent chains of increasing length were irradiated, nascent chain photocross-linking to translocon components, Sec61α and TRAM, was replaced by efficient photocross-linking solely to a protein identified by immunoprecipitation as the STT3 subunit of the OST. No cross-linking was observed in the absence of a cryptic sequence or in the presence of a competitive peptide substrate of the OST. As no significant nascent chain photocross-linking to other OST subunits was detected in these fully assembled translocation and integration intermediates, our results strongly indicate that the nascent chain portion of the OST active site is located in STT3

    A Call for Urgent Monitoring of Food and Water Security Based on Relevant Indicators for the Arctic

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    This perspective paper argues for an urgent need to monitor a set of 12 concrete, measurable indicators of food and water security in the Arctic over time. Such a quantitative indicator approach may be viewed as representing a reductionist rather than a holistic perspective, but is nevertheless necessary for actually knowing what reality aspects to monitor in order to accurately understand, quantify, and be able to project critical changes to food and water security of both indigenous and non-indigenous people in the Arctic. More relevant indicators may be developed in the future, taking us further toward reconciliation between reductionist and holistic approaches to change assessment and understanding. However, the potential of such further development to improved holistic change assessment is not an argument not to urgently start to monitor and quantify the changes in food and water security indicators that are immediately available and adequate for the Arctic context

    Golgi function and dysfunction in the first COG4-deficient CDG type II patient

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    The conserved oligomeric Golgi (COG) complex is a hetero-octameric complex essential for normal glycosylation and intra-Golgi transport. An increasing number of congenital disorder of glycosylation type II (CDG-II) mutations are found in COG subunits indicating its importance in glycosylation. We report a new CDG-II patient harbouring a p.R729W missense mutation in COG4 combined with a submicroscopical deletion. The resulting downregulation of COG4 expression additionally affects expression or stability of other lobe A subunits. Despite this, full complex formation was maintained albeit to a lower extent as shown by glycerol gradient centrifugation. Moreover, our data indicate that subunits are present in a cytosolic pool and full complex formation assists tethering preceding membrane fusion. By extending this study to four other known COG-deficient patients, we now present the first comparative analysis on defects in transport, glycosylation and Golgi ultrastructure in these patients. The observed structural and biochemical abnormalities correlate with the severity of the mutation, with the COG4 mutant being the mildest. All together our results indicate that intact COG complexes are required to maintain Golgi dynamics and its associated functions. According to the current CDG nomenclature, this newly identified deficiency is designated CDG-IIj
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