Co-infection with Bartonella bacilliformis and Mycobacterium spp. in a coastal region of Peru

Abstract Objective This study investigated an outbreak of Bartonellosis in a coastal region in Peru. Results A total of 70 (n = 70) samples with clinical criteria for the acute phase of Bartonellosis and a positive peripheral blood smear were included. 22.85% (n = 16) cases of the samples were positive for Bartonella bacilliformis by PCR and automatic sequencing. Of those positive samples, 62.5% (n = 10) cases were positive only for B. bacilliformis and 37.5% (n = 6) cases were positive to both Mycobacterium spp. and B. bacilliformis. The symptom frequencies were similar in patients diagnosed with Carrion’s disease and those co-infected with Mycobacterium spp. The most common symptoms were headaches, followed by malaise and arthralgia

Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

Use of unauthorized pesticides in primary agricultural foods, Peru (2011-2018) [Uso de plaguicidas no autorizados en alimentos agrícolas primarios, Perú (2011-2018)]

El monitoreo de contaminantes que afecten la inocuidad de alimentos agropecuarios primarios se inició el año 2011 en el Perú. Se efectuó una revisión documental de los informes de monitoreo publicados en el sitio web del Servicio Nacional de Sanidad Agropecuaria del Perú (SENASA) entre los años 2011 a 2020, sin embargo no hubo información completa sobre la concentración de plaguicidas no autorizados (PNA) en relación al límite máximo de residuos y por región geográfica, y tipo de contaminante, particularmente los años 2019 y 2020 por lo que el análisis de restringe al período 2011-2018 verificándose el uso de no menos de 20 plaguicidas no autorizados de los cuales se han efectuado un mínimo de dos aplicaciones por cultivo, siendo los cultivos con mayor uso de PNA el limón (7 PNA); tomate, mandarina y uvas (5 PNA); banano (4 PNA); y naranjas y pallar (3 PNA), siendo clorpirifos y carbendazim los PNA que fueron utilizados hasta en cinco cultivos lo que se explicaría por su amplio espectro de acción. Se requiere monitoreo para determinar las concentraciones de los PNA según cultivo, en relación a los límites máximos de residuo, y al período de retiro.The monitoring of contaminants that affect the safety of primary agricultural foods began in 2011 in Peru. A documentary review of the monitoring reports published on the website of the National Agricultural Health Service of Peru (SENASA) was carried out between the years 2011 to 2020, however there was no complete information about concentration of unauthorized pesticides (UP) in relation to the maximum limit of residues and by geographic region, and type of pollutant, particularly the years 2019 and 2020, so the analysis is restricted to the period 2011-2018 verifying the use of no less than 20 unauthorized pesticides of which a minimum of two have been made. applications per crop, being the crops with the highest use of UP: lemon (7 UP); tomato, mandarin and grapes (5 UP); banana (4 UP); and oranges and pallar (3 UP), being chlorpyrifos and carbendazim the UP that were used in up to five crops, which would be explained by their wide spectrum of action. Monitoring is required to determine the concentrations of the UP according to culture, in relation to the maximum residue limits, and to the withdrawal period

Co-infection with Bartonella bacilliformis and Mycobacterium spp. in a coastal region of Peru

Abstract Objective This study investigated an outbreak of Bartonellosis in a coastal region in Peru. Results A total of 70 (n = 70) samples with clinical criteria for the acute phase of Bartonellosis and a positive peripheral blood smear were included. 22.85% (n = 16) cases of the samples were positive for Bartonella bacilliformis by PCR and automatic sequencing. Of those positive samples, 62.5% (n = 10) cases were positive only for B. bacilliformis and 37.5% (n = 6) cases were positive to both Mycobacterium spp. and B. bacilliformis. The symptom frequencies were similar in patients diagnosed with Carrion’s disease and those co-infected with Mycobacterium spp. The most common symptoms were headaches, followed by malaise and arthralgia

The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study

AimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P ConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease