Transcript profiling of the endothelial cell's temporal response to hypoxia

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Productivity and participation values for cooperative goals to limit free riding and promote performance in international joint ventures

This study holds that the development of cooperative goals instead of competitive goals among joint venture partners helps to limit free riding and promote performance in IJVs. The results collected from 75 pairs of Chinese and foreign joint venture partners suggest that productivity and participation values strengthen the partners’ beliefs that their goals are cooperatively related, which in turn, reduces free riding and promotes performance, whereas competitive goals promote free riding and obstruct joint performance. The paper also suggests how cooperation and competition research can complement established theoretical frameworks on the conditions and dynamics that result in IJV productivity

Genome of the Bacterium Streptococcus pneumoniae Strain R6

Streptococcus pneumoniae is among the most significant causes of bacterial disease in humans. Here we report the 2,038,615-bp genomic sequence of the gram-positive bacterium S. pneumoniae R6. Because the R6 strain is avirulent and, more importantly, because it is readily transformed with DNA from homologous species and many heterologous species, it is the principal platform for investigation of the biology of this important pathogen. It is also used as a primary vehicle for genomics-based development of antibiotics for gram-positive bacteria. In our analysis of the genome, we identified a large number of new uncharacterized genes predicted to encode proteins that either reside on the surface of the cell or are secreted. Among those proteins there may be new targets for vaccine and antibiotic development