1,620 research outputs found

    Finite-Temperature Mott Transition in the Two-Dimensional Hubbard Model

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    Mott transitions are studied in the two-dimensional Hubbard model by a non-perturbative theory of correlator projection that systematically includes spatial correlations into the dynamical mean-field approximation. Introducing a nonzero second-neighbor transfer, a first-order Mott transition appears at finite temperatures and ends at a critical point or curve.Comment: 2 pages, to appear in J. Mag. Mag. Mat. as proceedings of the International Conference on Magnetism 200

    Enhancing Ocean Literacy Using Real-Time Data

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    Ocean literacy is the understanding of our relationship with the ocean and the crucial services that the ocean provides to society and other living organisms (Cava et al., 2005). In 2004, a number of ocean science and educational communities adopted seven essential ocean literacy principles1 (Cava et al., 2005). These principles were further broken down into concepts, which were designed to teach science standards using an ocean orientation. Most state science standards do not specifically address these ocean principles but they have been categorized according to the National Science Educational Standards by discipline and overlap with the other traditional science disciplines. Hoffman and Barstow (2007) noted that no state addresses more than 20 of the 35 fundamental ocean concepts. Ten of the 35 concepts that were more biology focused were not included in their study. They also noted that more research needs to be conducted to evaluate whether students learn core science concepts and process skills using ocean literacy as the primary curriculum

    Investigating Coastal Processes and Nitrate Levels in the Elkhorn Slough Using Real-Time Data

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    The primary objective of this activity is to predict how coastal processes, such as tides, affect salinity, temperature, and nitrate levels in a type of estuary, called a slough. Real-time data from the Elkhorn Slough National Estuarine Research Reserve in Monterey, California, will be used to test predictions. In addition to collecting, graphing, and interpreting real-time data, students will learn how nitrates enter the estuary, and they will gain a better understanding of the interconnectedness of all bodies of water, especially estuaries

    Iodo-Nonoxynol-9-Derivatives and Methods for Their Use

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    Mono- and di-iodinated nonoxynol-9-derivatives and methods for their use are disclosed

    Improvement of Insulin Sensitivity by Isoenergy High Carbohydrate Traditional Asian Diet: A Randomized Controlled Pilot Feasibility Study

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    The prevalence of diabetes is rising dramatically among Asians, with increased consumption of the typical Western diet as one possible cause. We explored the metabolic responses in East Asian Americans (AA) and Caucasian Americans (CA) when transitioning from a traditional Asian diet (TAD) to a typical Western diet (TWD), which has not been reported before. This 16-week randomized control pilot feasibility study, included 28AA and 22CA who were at risk of developing type 2 diabetes. Eight weeks of TAD were provided to all participants, followed by 8 weeks of isoenergy TWD (intervention) or TAD (control). Anthropometric measures, lipid profile, insulin resistance and inflammatory markers were assessed. While on TAD, both AA and CA improved in insulin AUC (−960.2 ”U/mL×h, P = 0.001) and reduced in weight (−1.6 kg; P<0.001), body fat (−1.7%, P<0.001) and trunk fat (−2.2%, P<0.001). Comparing changes from TAD to TWD, AA had a smaller weight gain (−1.8 to 0.3 kg, P<0.001) than CA (−1.4 to 0.9 kg, P = 0.001), but a greater increase in insulin AUC (AA: −1402.4 to 606.2 ”U/mL×h, P = 0.015 vs CA: −466.0 to 223.5 ”U/mL×h, P = 0.034) and homeostatic static model assessment-insulin resistance (HOMA-IR) (AA: −0.3 to 0.2, P = 0.042 vs CA: −0.1 to 0.0, P = 0.221). Despite efforts to maintain isoenergy state and consumption of similar energy, TAD induced weight loss and improved insulin sensitivity in both groups, while TWD worsened the metabolic profile. Trial Registration: ClinicalTrials.gov NCT0037954

    Operator projection method applied to the single-particle Green's function in the Hubbard model

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    A new non-perturbative framework for many-body correlated systems is formulated by extending the operator projection method (OPM). This method offers a systematic expansion which enables us to project into the low-energy structure after extracting the higher-energy hierarchy. This method also opens a way to systematically take into account the effects of collective excitations. The Mott-Hubbard metal-insulator transition in the Hubbard model is studied by means of this projection beyond the second order by taking into account magnetic and charge fluctuations in the presence of the high-energy Mott-Hubbard structure. At half filling, the Mott-Hubbard gap is correctly eproduced between the separated two bands. Near half filling, a strongly renormalized low-energy single-particle excitations coexisting with the Mott-Hubbard bands are shown to appear. Signifcance of momentum-dependent self-energy in the results is stressed.Comment: 6 pages, final version to appear in J. Phys. Soc. Jp

    Classification of large circulating tumor cells isolated with ultra-high throughput microfluidic Vortex technology.

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    Circulating tumor cells (CTCs) are emerging as rare but clinically significant non-invasive cellular biomarkers for cancer patient prognosis, treatment selection, and treatment monitoring. Current CTC isolation approaches, such as immunoaffinity, filtration, or size-based techniques, are often limited by throughput, purity, large output volumes, or inability to obtain viable cells for downstream analysis. For all technologies, traditional immunofluorescent staining alone has been employed to distinguish and confirm the presence of isolated CTCs among contaminating blood cells, although cells isolated by size may express vastly different phenotypes. Consequently, CTC definitions have been non-trivial, researcher-dependent, and evolving. Here we describe a complete set of objective criteria, leveraging well-established cytomorphological features of malignancy, by which we identify large CTCs. We apply the criteria to CTCs enriched from stage IV lung and breast cancer patient blood samples using the High Throughput Vortex Chip (Vortex HT), an improved microfluidic technology for the label-free, size-based enrichment and concentration of rare cells. We achieve improved capture efficiency (up to 83%), high speed of processing (8 mL/min of 10x diluted blood, or 800 ΌL/min of whole blood), and high purity (avg. background of 28.8±23.6 white blood cells per mL of whole blood). We show markedly improved performance of CTC capture (84% positive test rate) in comparison to previous Vortex designs and the current FDA-approved gold standard CellSearch assay. The results demonstrate the ability to quickly collect viable and pure populations of abnormal large circulating cells unbiased by molecular characteristics, which helps uncover further heterogeneity in these cells

    The Global Ocean Biogeochemistry (GO-BGC) array of profiling floats to observe changing ocean chemistry and biology

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    © The Author(s), 2022. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Matsumoto, G., Johnson, K., Riser, S., Talley, L., Wijffels, S., & Hotinski, R. The Global Ocean Biogeochemistry (GO-BGC) array of profiling floats to observe changing ocean chemistry and biology. Marine Technology Society Journal, 56(3), (2022): 122–123, https://doi.org/10.4031/mtsj.56.3.25.The Global Ocean Biogeochemistry (GO-BGC) Array is a project funded by the US National Science Foundation to build a global network of chemical and biological sensors on Argo profiling floats. The network will monitor biogeochemical cycles and ocean health. The floats will collect from a depth of 2,000 meters to the surface, augmenting the existing Argo array that monitors ocean temperature and salinity. Data will be made freely available within a day of being collected via the Argo data system. These data will allow scientists to pursue fundamental questions concerning ocean ecosystems, monitor ocean health and productivity, and observe the elemental cycles of carbon, oxygen, and nitrogen through all seasons of the year. Such essential data are needed to improve computer models of ocean fisheries and climate, to monitor and forecast the effects of ocean warming and ocean acidification on sea life, and to address key questions identified in “Sea Change: 2015–2025 Decadal Survey of Ocean Sciences” such as: What is the ocean’s role in regulating the carbon cycle? What are the natural and anthropogenic drivers of open ocean deoxygenation? What are the consequences of ocean acidification? How do physical changes in mixing and circulation affect nutrient availability and ocean productivity?Funding for the GO-BGC Array is provided through the NSF’s Mid-Scale Research Infrastructure-2 Program (MSRI-2; NSF Award 1946578)

    Quantum critical Bose gas in the two-dimensional limit in the honeycomb antiferromagnet YbCl3_3 under magnetic fields

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    BEC is a quantum phenomenon, where a macroscopic number of bosons occupy the lowest energy state and acquire coherence at low temperatures. It is realized not only in 4^4He and dilute atomic gases, but also in quantum magnets, where hardcore bosons, introduced by the Matsubara-Matsuda transformation of spins, condense. In 3D antiferromagnets, an XY-type long-range ordering (LRO) occurs near a magnetic-field-induced transition to a fully polarized state (FP) and has been successfully described as a BEC in the last few decades. An attractive extension of the BEC in 3D magnets is to make their 2D analogue. For a strictly 2D system, BEC cannot take place due to the presence of a finite density of states at zero energy, and a Berezinskii-Kosterlitz-Thouless (BKT) transition may instead emerge. In a realistic quasi-2D magnet consisting of stacked 2D magnets, a small but finite interlayer coupling stabilizes marginal LRO and BEC, but such that 2D physics, including BKT fluctuations, is still expected to dominate. A few systems were reported to show such 2D-limit BEC, but at very high magnetic fields that are difficult to access. The honeycomb SS = 1/2 Heisenberg antiferromagnet YbCl3_3 with an intra-layer coupling J∌J\sim 5 K exhibits a transition to a FP state at a low in-plane magnetic field of HsH_{\rm s} = 5.93 T. Here, we demonstrate that the LRO right below HsH_{\rm s} is a BEC in the 2D-limit stabilized by an extremely small interlayer coupling J⊄J_{\perp} of 10−5J^{-5}J. At the quantum critical point Hs, we capture 2D-limit quantum fluctuations as the formation of a highly mobile, interacting 2D Bose gas in the dilute limit. A much-reduced effective boson-boson repulsion Ueff as compared with that of a prototypical 3D system indicates the presence of a logarithmic renormalization of interaction unique to 2D.Comment: 24 pages, 12 figure

    Operator Projection Theory for Electron Differentiation in Underdoped Cuprate Superconductors

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    Metals approaching the Mott insulator generate a new hierarchy in the electronic structure accompanied by a momentum dependent electron differentiation, beyond the Mott-Hubbard, Brinkman-Rice and Slater pictures of the Mott transition. To consider such nonlinear phenomenon, we develop an analytic nonperturbative theory based on operator projections combined with a self-consistent treatment of the low-energy excitations. This reproduces the formation of the Hubbard bands, Mott gap, spin fluctuations, mass divergence, diverging charge compressibility, and strongly renormalized flat and damped dispersion similar to angle-resolved photoemission data in high-T_c cuprates. Main structures in electronic spectra show a remarkable similarity to numerical results.Comment: 11 pages, presented at ``Spectroscopies of Novel Superconductors 2001'
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