Évaluation des performances d'un récepteur multi-usagers à annulation d'interférences dans un réseau de téléphonie cellulaire utilisant le spread signature CDMA

Le canal radiomobile -- Direct sequence CDMA -- Spread signature CDMA -- Le récepteur multi-usagers étudié -- Conclusion sur la théorie : le rôle de l'orthonormalité et de la complétude -- Performances "prévues" -- Le contrôle de puissance -- Cas d'un contrôle de puissance parfait -- Cas d'un contrôle de puissance imparfait -- La complexité de l'algorithme du récepteur -- Choix des paramètres -- Évaluation de la qualité des signatures utilisées

Un modèle de canal multi-trajets appliqué à la simulation rapide du lien UMTS

- Cet article propose une méthode de simulation simplifiée du lien radio. Son originalité consiste en la modélisation simplifiée du récepteur et du canal, qui reste très fidèle. Cette méthode de simulation rapide est très précise et le gain en complexité est important. L'exemple des services 12.2 et 64 kbps de l'UMTS FDD à 3 et 120 km/h pour les canaux du 3GPP montre très peu de différence entre les performances des simulateurs traditionnel et simplifié

Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses

SummarySystems approaches for the study of immune signaling pathways have been traditionally based on purified cells or cultured lines. However, in vivo responses involve the coordinated action of multiple cell types, which interact to establish an inflammatory microenvironment. We employed standardized whole-blood stimulation systems to test the hypothesis that responses to Toll-like receptor ligands or whole microbes can be defined by the transcriptional signatures of key cytokines. We found 44 genes, identified using Support Vector Machine learning, that captured the diversity of complex innate immune responses with improved segregation between distinct stimuli. Furthermore, we used donor variability to identify shared inter-cellular pathways and trace cytokine loops involved in gene expression. This provides strategies for dimension reduction of large datasets and deconvolution of innate immune responses applicable for characterizing immunomodulatory molecules. Moreover, we provide an interactive R-Shiny application with healthy donor reference values for induced inflammatory genes

Utilisation des objets connectés en recherche clinique

International audienc

Estudos comparados: sua epistemologia e sua historicidade Compared studies: epistemology and historicity

A comparação parte da analogia que é o processo de perceber as diferenças e semelhanças na relação com o outro, pessoas e objetos. A questão do outro e do reconhecimento da alteridade é a base do conhecimento da identidade de si mesmo e da distinção em relação aos demais seres. Assim como as ciências têm uma gênese e um desenvolvimento ao longo da história da humanidade, as questões epistemológicas também possuem uma historicidade. Ao refletir sobre a verdade dos estudos comparados, sobre sua epistemologia, vemos que eles se fazem compreensíveis e convincentes na medida em que a sociologia, a história, a antropologia, a política, a educação etc. são remetidas à história de sua elaboração. Nelas estão presentes os sujeitos sociais que as produziram e as ideologias que permearam suas ideias sobre a verdade científica. Neste texto, após algumas questões preliminares que o tratamento do tema requer, a saber, conhecimento e verdade, história e historicidade e o sentido da comparação, apresento alguns autores de referência que se ocuparam do tema e, a seguir, alguns estudos comparativos que desenvolvi em elaborações anteriores sobre a questão.<br>The comparison is based on the analogy that is the process of perceiving the differences and similarities in the relationship with the other, people and objects. The issue about the other and the recognition of alterity is the basis of the knowledge of the very own identity and of the distinction in regards to the other beings. Just as sciences have a genesis and a development along the mankind history, the epistemological issues also bear a historicity. When reflecting about the truth of compared studies, about their epistemology, we see they are understandable and convincing as the sociology, the history, the anthropology, the politics, the education etc. refer to the history of their creation. There in the social subjects who produced them are present, as well as the ideologies that pervaded their ideas regarding the scientific truth. In this text, after some preliminary questions required by the handling of the issue, which are, knowledge and truth, history and historicity and the meaning of comparison, I present some reference authors who dealt with this theme and, as follows, some comparative studies I developed in previous creations regarding the matter