Estudio de procesos posdeposicionales en hueso, asta y sílex

El presente estudio tiene como objeto el análisis de las alteraciones superficiales macroscópicas de diferentes materias primas (hueso, asta y diferentes tipos de sílex) tras su tratamiento térmico bajo una hoguera de 30 cm de diámetro, y su relación con los procesos postdeposicionales y azarosos que pudieran acontecer en las etapas tempranas del dominio técnico del fuego y la industria lítica. Tras el análisis de las alteraciones se procederá con la interpretación de los resultadosThe aim of this work is analyzing the macroscopic alterations of the surface of different raw materials (bone, antler and different types of flint) after heat treatment in a 30 cm diameter bonfire, and their relationship with random and post-depositional processes that could happen in earlier stages of the technical knowledge of fire and lithic industry. The interpretation of the results will be carried out after the analysis of the alteration

Image Pivoting for Learning Multilingual Multimodal Representations

In this paper we propose a model to learn multimodal multilingual representations for matching images and sentences in different languages, with the aim of advancing multilingual versions of image search and image understanding. Our model learns a common representation for images and their descriptions in two different languages (which need not be parallel) by considering the image as a pivot between two languages. We introduce a new pairwise ranking loss function which can handle both symmetric and asymmetric similarity between the two modalities. We evaluate our models on image-description ranking for German and English, and on semantic textual similarity of image descriptions in English. In both cases we achieve state-of-the-art performance.Comment: 7 pages, EMNLP 201

Performance of “Monrepos” as a cherry rootstock (Prunus avium L.) in the Ebro Valley

Se ha evaluado el comportamiento agronómico de “Monrepós”, un nuevo patrón para cerezo seleccionado en el CITA de Aragón, perteneciente al grupo de ciruelos denominado de crecimiento rápido. El estudio se llevó a cabo durante 9 años en la zona del Valle del Ebro (España), en un suelo pesado y calizo, con la variedad Compact Stella injertada sobre 5 patrones utilizados para cerezo. Se evaluó el vigor, la producción y productividad, su capacidad de propagación, tanto por estaquilla leñosa como in vitro, la fecha de floración y densidad floral, así como el comportamiento al injerto con un amplio número de variedades de cerezo. El patrón “Monrepós” indujo a la variedad un vigor y una producción acumulada más elevada que el resto de los patrones analizados, así como una buena compatibilidad patrón-injerto con todas las variedades ensayadas y una elevada capacidad de enraizamiento, tanto por estaquilla leñosa como in vitro, cercana al 90%.The agronomic behaviour of “Monrepos”, a new plum rootstock for cherry selected at CITA of Aragon, has been evaluated. The study was performed during 9 years in the Ebro Valley (Spain), on a heavy and calcareous soil, with the cultivar Compact Stella grafted on 5 rootstocks used for cherry cultivars. Different agronomic characteristics were evaluated: vigour, production and productivity as well as propagation, bloom time and graft compatibility with a wide range of cherry cultivars. “Monrepos” roostocks showed a grow vigour and production higher than the evaluated roostocks, as well as a good compatibility with all the cultivars evaluated and a good rooting aptitude, by in vitro and hardwood cuttings methods.Publishe

Study of the bufadienolides of the skin secretion of green toads (Bufo viridis Laur, 1758)

The composition of the skin secretion of Bufo viridis toads, which inhabit the Kharkov region, has been studied in this work

Alien Registration- Gella, Sophie (Portland, Cumberland County)

https://digitalmaine.com/alien_docs/32148/thumbnail.jp

Uridine 5′-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation

In response to peripheral nerve injury, Schwann cells adopt a migratory phenotype and modify the extracellular matrix to make it permissive for cell migration and axonal re-growth. Uridine 5′-triphosphate (UTP) and other nucleotides are released during nerve injury and activate purinergic receptors expressed on the Schwann cell surface, but little is known about the involvement of purine signalling in wound healing. We studied the effect of UTP on Schwannoma cell migration and wound closure and the intracellular signaling pathways involved. We found that UTP treatment induced Schwannoma cell migration through activation of P2Y2 receptors and through the increase of extracellular matrix metalloproteinase-2 (MMP-2) activation and expression. Knockdown P2Y2 receptor or MMP-2 expression greatly reduced wound closure and MMP-2 activation induced by UTP. MMP-2 activation evoked by injury or UTP was also mediated by phosphorylation of all 3 major mitogen-activated protein kinases (MAPKs): JNK, ERK1/2, and p38. Inhibition of these MAPK pathways decreased both MMP-2 activation and cell migration. Interestingly, MAPK phosphorylation evoked by UTP exhibited a biphasic pattern, with an early transient phosphorylation 5 min after treatment, and a late and sustained phosphorylation that appeared at 6 h and lasted up to 24 h. Inhibition of MMP-2 activity selectively blocked the late, but not the transient, phase of MAPK activation. These results suggest that MMP-2 activation and late MAPK phosphorylation are part of a positive feedback mechanism to maintain the migratory phenotype for wound healing. In conclusion, our findings show that treatment with UTP stimulates in vitro Schwannoma cell migration and wound repair through a MMP-2-dependent mechanism via P2Y2 receptors and MAPK pathway activation. © 2014 Lamarca et al.This research was supported by an unrestricted research grant from Ferrer S.A. (Barcelona, Spain) and by grant SAF2011-23550 from Ministerio de Economia y Competitividad of SpainPeer Reviewe