A clinical study to evaluate the Upashayatmaka effect of Trikarshika Kwatha in Amavata (Rheumatoid Arthritis)

Background: Amavata is the disease which is caused due to the involvement of Ama and Vata. Rheumatoid Arthritis is having significant parlance with Amavata in terms of the symptoms produced in the body. The prevalence of Rheumatoid Arthritis is approximately 0.8% of the population. Women are affected approximately three times more often than men. Objectives: To carry out comprehensive literary work covering classical and modern aspect of Amavata and to evaluate the Upashayatmaka effect of Trikarshika Kwatha in Amavata. Methodology: A Single group open labelled clinical study with pre and post test design was carried out in 30 subjects of Amavata aged 16-70 years. Patients were analyzed and selected accordingly who fulfilled the diagnostic and inclusion criteria. Trikarshika Kwatha 48ml twice a day before food was given for 15 days. Detailed proforma was prepared to assess the observation. Results: All the parameters were highly statistically significant with p<0.001 except RA Factor which was statistically insignificant throughout the study. Conclusion: Trikarshika Kwatha proved beneficial in reducing the symptoms of Amavata

Understanding the etiopathogenesis of Uttana Vatarakta (peripheral vascular disease) - An Observational Study

Advanced life style and changing food habits affects the activities of individual which leads to many diseases and Peripheral Vascular Diseases are one among them. They are characterized by reduction of blood flow and oxygen supply through peripheral vascular vessels. This can happen in arteries or veins. The incidence of Varicose vein is more common with age and high prevalence is after 30 years of life. PAD occurs in patients over 40 years old; the highest incidence occurs in the sixth and seventh decades of life and it affects 10-15% of the general population. The symptoms of Uttana Vatarakta owing to the Margavarana pathology simulate with the symptoms of Peripheral vascular diseases and some of the etiological factors of Uttana Vatarakta in the writing are specific in inclining Peripheral Vascular Diseases. Ayurveda emphasise the importance of study on etiopathogenesis of disease before the planning of treatment protocol. In this study an effort is done to identify the Nidanas and pattern of Samprapti in relation with Peripheral vascular diseases for the better understanding of different clinical presentations of Uttana Vatarakta

Etiopathological and diagnostic study of Margavaranajanya Hridroga w.s.r. to Coronary Artery Disease - An Observational Study

The incidence of cardiac diseases is increasing at an alarming rate in our society due to sedentary lifestyle as an impact of western culture. In India, many studies have reported increasing coronary artery disease incidence over 60 years. One in 4 deaths in India are due to coronary artery disease. So thorough understanding of pathogenesis of this disease is very important. Ayurveda literature elaborates multiple maladies related to heart under Hridroga. Margavarana is a unique pathology explained in our classics. Various dietary, behavioural, psychological factors contribute to morbid accumulation of Kapha and Medas leading to Shonita Abhishyandana. Further morbid state of Shonita Abhishyandana by Upalepa of Dhamani culminates in development of Dhamani Prathicchaya. Eventually due to Siraaja Granthi Dhamani Prathichhaya ends up in Margavarna and is the leading pathology of Hridroga. In the realm of conventional medicine, it is said that sedentary life style is the major cause of morbid accumulation of fat in the body leading to metabolic syndrome. It is characterised by dyslipidemia which in turn leading to atherosclerosis. Atherosclerosis predisposes the thromboembolism and complete obliteration of blood circulation within the vessel. Hence, in the present study an endeavour is made to corelate the concept of Coronary artery disease and its ill effects with the classical reference regarding the concept of Margavarana pathology occurring in the Hridaya causing Margavaranajanya Hridroga and also its diagnosis through the modern tools

Understanding the etiopathogenesis of Katigraha - An Observational Study

Katigraha is one among the Vataja Nanatmaja Vyadhi which simulates with the signs and symptoms of Low Back pain. It continues to be the most common health concern for which patients seek primary care therapy. Our Acharyas explains Katigraha as a Lakshana in various Vatavyadhi and in other diseases. Here, Katigraha indicates a disease condition of the back associated with pain and stiff movements. As Gada Nigraha clearly states pain is produced due to stiffness produced by Saama or Niraama Vayu movement in to Kati hence this suggests of presence of Dhatu Kshayatmaka and Marga Avarodhaka type of Samprapti. Hence in this context Katigraha denotes a group of symptoms characterized by the restriction of movements of Kati region in which pain would be a main feature as Graha alternatively means pain as restriction is said to produce pain in the particular region. The backache or lumbago is one of conditions which results from violation of bio mechanics of spine as it results when the physical and mental strain and faulty postures alter anthropometrical precision. The 70-80% of world population suffers from backache at some point of their life. As the back pain is very subjective in nature, there are very few objectives finding in history, clinical examination and even on extensive radiological or laboratory investigation

An observational study to explore the Samprapti Ghatakas in Hypothyroidism

Background: Hypothyroidism is the most common functional disorder of the thyroid gland. It is a hypometabolic clinical state resulting from inadequate production of thyroid hormones for prolonged periods. The prevalence of this disease in India is 6% and more than 10 million cases per year are reported. It is a multisystemic disorder which has a wide range of clinical symptoms. This condition is not mentioned in Ayurveda classics by any specified name. In Ayurveda, determining the elements that contribute to Samprapti is essential in developing a treatment plan. Hence, the current study attempts to evaluate the Samprapti Ghatakas and as a result, formulate probable Samprapti. Objectives: To study and explore the Samprapti Ghatakas of hypothyroidism and to propose possible Samprapti. Methods: The study was conducted in 100 cases of hypothyroidism between the age of 16 to 70 years. A case proforma was prepared which includes history taking, physical signs and symptoms and required examination. The calculations were done in Microsoft excel and the values obtained were assessed on the basis of percentage of individual parameters in relation with Samprapti Ghatakas of hypothyroidism. Results: Kapha and Vata are the main Doshas involved in the Samprapti. Important Dooshyas are Rasa, Meda. Agni involved is Dhatwagni and the disease is caused primarily due to Dhatwagnimandya. Udakavaha, Annavaha, Medovaha, Swedavaha, Purishavaha, Rasavaha are the main Srotas involved with Sanga type of Srotodushti. Udbhava Sthana can be considered as Amashaya; Sanchara Sthana, Vyakta Sthana and Adhishtana is Sarva Shareera. All the three Rogamarga are involved

Understanding the etiology of Arshas - An Observational Study

Lifestyle disorders are becoming the major cause of ill health and disability worldwide. Hemorrhoid is one such disease which makes human life miserable. Hemorrhoids is nothing but the varicosity of blood vessels found inside or around the bottom the rectum and anus. Age group of 45-65yrs, it is estimated that 50-85% of people around the world have hemorrhoids.[1] In India 75% of the population is estimated. Clinical features of hemorrhoid resembles with Arshas. In Ayurveda classics, there are detail information about the Aharaja (Anashana, Adhyashana), Viharaja (Ativyayama, Divaswapna), Manasika (Shoka, Krodha) and Agantujanidanas (Gudakharshana, Vastivibhrama) which are responsible for the manifestation of Arsha. Common symptoms are itching, burning sensation and pain in the region of Guda and finally bleeds.[2] Maintaining the health and providing the health is the main motto of Ayurveda. This ground incorporates usage of different remedies with focusing on Nidana Parivarjana. Thus understanding the Nidana Parivarjana is the prime importance. In this study an effort is done to identify the prime causative factors in deal to Arshas

An insight on Vyadhikshamatva and Bala

A good yield cannot be obtained from a seed sown in a non-fertile land, likewise an external cause cannot produce any morbidity in a Balayukta Deha. Health and disease is an integral element of an individual’s life. Everyone is not equally susceptible to diseases, but it depends on Vyadhikshamatva of a person. The core aim of Ayurveda and the definition of Vyadhikshamatva by Chakrapani carries a great resemblance. Swasthasya Swaasthya Rakshanam implies the same meaning of Vyadhi-Utpadaka Prathibandhakatvam and Aturasya Vikaraprasamanam connotes the term Vyadhibala Virodhitvam. Optimum Vyadhikshamatva can steer away one from origin and progression of diseases. It is influenced by factors such as Bala, Ojas, Prakrita Kapha, Agni, etc. Vyadhikshamatva is invariably related to Bala, which is decided from the time of Shukrashonitha Samyoga to Ahara and Vihara of an individual along with seasonal changes. This review article is an effort to understand Vyadhikshamatva in terms of Bala