Background: Amavata is the disease which is caused due to the involvement of Ama and Vata. Rheumatoid Arthritis is having significant parlance with Amavata in terms of the symptoms produced in the body. The prevalence of Rheumatoid Arthritis is approximately 0.8% of the population. Women are affected approximately three times more often than men. Objectives: To carry out comprehensive literary work covering classical and modern aspect of Amavata and to evaluate the Upashayatmaka effect of Trikarshika Kwatha in Amavata. Methodology: A Single group open labelled clinical study with pre and post test design was carried out in 30 subjects of Amavata aged 16-70 years. Patients were analyzed and selected accordingly who fulfilled the diagnostic and inclusion criteria. Trikarshika Kwatha 48ml twice a day before food was given for 15 days. Detailed proforma was prepared to assess the observation. Results: All the parameters were highly statistically significant with p<0.001 except RA Factor which was statistically insignificant throughout the study. Conclusion: Trikarshika Kwatha proved beneficial in reducing the symptoms of Amavata
