Aerodynamic Design of Active Flow Control on the Vertical Tail

t In this work the application of active flow control with tangential blowing is investigated to delay flow separation on the vertical tailplane (VTP) of a modern passenger transport aircraft. While tangential blowing is known to be effective on wing geometries, the aim of this work is to design the aerodynamic part of a blowing system in order to show two things: That tangential blowing can be effective on a VTP as well and that its efficiency can be increased when deviating from a full span slot. The design is done using numerical methods based on the Reynolds-averaged Navier-Stokes equations. The sizing case for the area of the VTP is a one-sided engine failure at low speed accompanied by small-to-medium sideslip angles. To compensate the asymmetric thrust, a large rudder deflection is needed to achieve the high side force required. The objective here is to increase the side force by delaying the flow separation to allow reducing the VTP area to cruise flight requirements, saving drag and weight. The design case mentioned leads to non-linear aerodynamic characteristics caused by partial flow separation. These differ from a typical passenger aircraft wing geometry due to the VTP’s low-aspect ratio, highly-swept planform. Therefore, understanding the complex three-dimensional baseline flow over the VTP is the basis of this work. Building on this, the tangential blowing slot is developed in three steps. First, a 2D section is used to analyze the effects of geometry changes in the vicinity of the slot. In a next step this geometry is extended to 2.5D where a constant chord geometry with extension in spanwise direction is used. This allows accounting for the large sweep angle of the VTP and opens the possibility to examine apart from a continuous full span slot also discrete slots. Introducing the discrete slots leads to the creation of a vortex system over the rudder which helps to attach the flow not only in the path of the jet but also in between the jets in spanwise direction. The slot width and the gap between the slots are varied to optimize this vortex system. The findings were in a last step transferred to the 3D vertical tailplane. Due to the reduction of the slot extension over the span a considerable mass flow reduction of around 50% could be achieved for the same increase in side force coefficient. Thus it could be shown that the side force coefficient can be significantly increased using tangential blowing which is more efficient when using discrete slots

Fatigue behavior of gold thin films at elevated temperatures studied by bulge testing

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Adaptierte Version des Planspiels Energetingen für Hauptschulen

Ein Projektbericht mit Materalien für die Umsetzun

Relevance of Lysine Snorkeling in the Outer Transmembrane Domain of Small Viral Potassium Ion Channels

Transmembrane domains (TMDs) are often flanked by Lys or Arg because they keep their aliphatic parts in the bilayer and their charged groups in the polar interface. Here we examine the relevance of this so-called “snorkeling” of a cationic amino acid, which is conserved in the outer TMD of small viral K+ channels. Experimentally, snorkeling activity is not mandatory for KcvPBCV-1 because K29 can be replaced by most of the natural amino acids without any corruption of function. Two similar channels, KcvATCV-1 and KcvMT325, lack a cytosolic N-terminus, and neutralization of their equivalent cationic amino acids inhibits their function. To understand the variable importance of the cationic amino acids, we reanalyzed molecular dynamics simulations of KcvPBCV-1 and N-terminally truncated mutants; the truncated mutants mimic KcvATCV-1 and KcvMT325. Structures were analyzed with respect to membrane positioning in relation to the orientation of K29. The results indicate that the architecture of the protein (including the selectivity filter) is only weakly dependent on TMD length and protonation of K29. The penetration depth of Lys in a given protonation state is independent of the TMD architecture, which leads to a distortion of shorter proteins. The data imply that snorkeling can be important for K+ channels; however, its significance depends on the architecture of the entire TMD. The observation that the most severe N-terminal truncation causes the outer TMD to move toward the cytosolic side suggests that snorkeling becomes more relevant if TMDs are not stabilized in the membrane by other domains

Relevance of Lysine Snorkeling in the Outer Transmembrane Domain of Small Viral Potassium Ion Channels

Transmembrane domains (TMDs) are often flanked by Lys or Arg because they keep their aliphatic parts in the bilayer and their charged groups in the polar interface. Here we examine the relevance of this so-called “snorkeling” of a cationic amino acid, which is conserved in the outer TMD of small viral K+ channels. Experimentally, snorkeling activity is not mandatory for KcvPBCV-1 because K29 can be replaced by most of the natural amino acids without any corruption of function. Two similar channels, KcvATCV-1 and KcvMT325, lack a cytosolic N-terminus, and neutralization of their equivalent cationic amino acids inhibits their function. To understand the variable importance of the cationic amino acids, we reanalyzed molecular dynamics simulations of KcvPBCV-1 and N-terminally truncated mutants; the truncated mutants mimic KcvATCV-1 and KcvMT325. Structures were analyzed with respect to membrane positioning in relation to the orientation of K29. The results indicate that the architecture of the protein (including the selectivity filter) is only weakly dependent on TMD length and protonation of K29. The penetration depth of Lys in a given protonation state is independent of the TMD architecture, which leads to a distortion of shorter proteins. The data imply that snorkeling can be important for K+ channels; however, its significance depends on the architecture of the entire TMD. The observation that the most severe N-terminal truncation causes the outer TMD to move toward the cytosolic side suggests that snorkeling becomes more relevant if TMDs are not stabilized in the membrane by other domains

Searching for Supernovae in HETDEX Data Release 3

We have extracted 636 spectra taken at the positions of 583 transient sources from the third data release of the Hobby-Eberly Telescope Dark Energy eXperiment (HETDEX). The transients were discovered by the Zwicky Transient Facility (ZTF) during 2018-2022. The HETDEX spectra provide a potential means to obtain classifications for a large number of objects found by photometric surveys for free. We attempt to explore and classify the spectra by utilizing several template-matching techniques. We have identified two transient sources, ZTF20aatpoos = AT 2020fiz and ZTF19abdkelq, as supernova (SN) candidates. We classify AT 2020fiz as a Type IIP SN observed ∼10 days after explosion, and we propose ZTF19abdkelq as a likely Type Ia SN caught ∼40 days after maximum light. ZTF photometry of these two sources are consistent with their classifications as SNe. Beside these two objects, we have confirmed several ZTF transients as variable active galactic nuclei based on their spectral appearance, and determined the host galaxy types of several other ZTF transients

On the Size and Comoving Mass Density Evolution of Early-Type Galaxies

We present a simple, empirically motivated model that simultaneously predicts the evolution of the mean size and the comoving mass density of massive early-type galaxies from z=2 to the present. First we demonstrate that some size evolution of the population can be expected simply due to the continuous emergence of early-type galaxies. SDSS data reveal that in the present-day universe more compact early-type galaxies with a given dynamical mass have older stellar populations. In contrast, at a given stellar velocity dispersion, SDSS data show that there is no relation between size and age, which implies that the velocity dispersion can be used to estimate the epoch at which galaxies stopped forming stars, turning into early-type galaxies. Applying such a 'formation' criterion to a large sample of nearby early-type galaxies, we predict the redshift evolution in the size distribution and the comoving mass density. The resulting evolution in the mean size is roughly half of the observed evolution. Then we include a prescription for the merger histories of galaxies between the 'formation' redshift and the present, based on cosmological simulations of the assembly of dark matter halos. Such mergers after the transformation into an early-type galaxy are presumably dissipationless ('dry'), where the increase in size is expected to be approximately proportional to the increase in mass. This model successfully reproduces the observed evolution since z~2 in the mean size and in the comoving mass density of massive early-type galaxies. We conclude that the recently measured, substantial size evolution of early-type galaxies can be explained by the combined effect of the continuous emergence of galaxies as early types and their subsequent growth through dry merging.Comment: Accepted for publication in ApJ (13 pages, 5 figures), small changes to match journal versio

CD4+ T cell immunity to Salmonella is transient in the circulation

While Salmonella enterica is seen as an archetypal facultative intracellular bacterial pathogen where protection is mediated by CD4+ T cells, identifying circulating protective cells has proved very difficult, inhibiting steps to identify key antigen specificities. Exploiting a mouse model of vaccination, we show that the spleens of C57BL/6 mice vaccinated with live-attenuated Salmonella serovar Typhimurium (S. Typhimurium) strains carried a pool of IFN-γ+ CD4+ T cells that could adoptively transfer protection, but only transiently. Circulating Salmonella-reactive CD4+ T cells expressed the liver-homing chemokine receptor CXCR6, accumulated over time in the liver and assumed phenotypic characteristics associated with tissue-associated T cells. Liver memory CD4+ T cells showed TCR selection bias and their accumulation in the liver could be inhibited by blocking CXCL16. These data showed that the circulation of CD4+ T cells mediating immunity to Salmonella is limited to a brief window after which Salmonella-specific CD4+ T cells migrate to peripheral tissues. Our observations highlight the importance of triggering tissue-specific immunity against systemic infections