Improving sensitivity of oral fluid testing in IgG prevalence studies: application of mixture models to a rubella antibody survey

A method for the analysis of age-stratified antibody prevalence surveys is applied to a previously reported survey of antibody to rubella virus using oral fluid samples in which the sensitivity of the assay used was shown to be compromised. The age-specific distribution of the quantitative results of antibody tests using oral fluids is modelled as a mixture of strong positive, weak positive and negative components. This yields maximum likelihood estimates of the prevalence at each age and demonstrates that, when used in conjunction with mixture modelling techniques, the results of antibody prevalence studies using oral fluids accurately reflect those obtained using sera

Surface-wave interferometry on single subwavelength slit-groove structures fabricated on gold films

We apply the technique of far-field interferometry to measure the properties of surface waves generated by two-dimensional (2D) single subwavelength slit-groove structures on gold films. The effective surface index of refraction measured for the surface wave propagating over a distance of more than 12 microns is determined to be 1.016 with a measurement uncertainty of 0.004, to within experimental uncertainty of the expected bound surface plasmon-polariton (SPP) value for a Au/Air interface of 1.018. We compare these measurements to finite-difference-time-domain (FDTD) numerical simulations of the optical field transmission through these devices. We find excellent agreement between the measurements and the simulations for the surface index of refraction. The measurements also show that the surface wave propagation parameter exhibits transient behavior close to the slit, evolving smoothly from greater values asymptotically toward the value expected for the SPP over the first 2-3 microns of slit-groove distance. This behavior is confirmed by the FDTD simulations

A variational principle for fluid sloshing with vorticity, dynamically coupled to vessel motion

A variational principle is derived for two-dimensional incompressible rotational fluid flow with a free surface in a moving vessel when both the vessel and fluid motion are to be determined. The fluid is represented by a stream function and the vessel motion is represented by a path in the planar Euclidean group. Novelties in the formulation include how the pressure boundary condition is treated, the introduction of a stream function into the Euler-Poincar\'e variations, the derivation of free surface variations, and how the equations for the vessel path in the Euclidean group, coupled to the fluid motion, are generated automatically.Comment: 19 pages, 3 figure

TWO-CENTER EFFECTS IN ION-ATOM COLLISIONS: A Symposium in Honor of M. Eugene Rudd, Lincoln, NE May 1994 — Contents and Preface

Following a distinguished career in atomic physics, sketched in the accompanying biography, M. Eugene Rudd retired From the faculty of the University of Nebraska in the spring of 1993. In order to celebrate his many research accomplishments, a two day scientific conference, held on 13-14 May 1994, was organized in Lincoln. It was felt that the special spirit that Rudd brought to the lab would be highlighted by a conference designed to analyze in detail a subject of current research in which he was a pioneer: two center-effects in ion-atom ionizing collisions. Prior to 1980, primarily as a result of the experiments of Rudd and his co-workers, a standard view of ionizing collisions had developed. This view held that almost all the ionized electrons could be associated with either the ionized target or the receding projectile. The former, having mostly small momenta, were produced in soft collisions with the projectile, and emerged almost isotropically from the collision region. The remaining electrons had velocities similar to that of the projectile, and formed a cusp distribution about its velocity vector in the forward direction. Beginning in the mid-1980\u27s however, it became increasingly clear that electronic trajectories that were manifestly determined by a combination of the action of the two Coulomb centers, both target and projectile acting together, might be observed. The topic of this meeting was to consider such effects in detail. The speakers were chosen because of their expertise in this area, and included a number of Professor Rudd\u27s students and immediate colleagues. Eugen Merzbacher delivered the banquet address on The Crisis at the Physical Review. In addition to the four scientific sessions for invited speakers, a poster session was held with 17 contributions. We intend that this Festschrift will serve as a useful summary of the current status of this field, and as a goad starting point for researchers interested in studying this topic. We hope that it will also give the scientific community at large an indication of the influence of M. E. Rudd\u27s career, and of the high esteem in which his colleagues hold both it and him

Sensitivity of the superconducting state in thin films

For more than two decades, there have been reports on an unexpected metallic state separating the established superconducting and insulating phases of thin-film superconductors. To date, no theoretical explanation has been able to fully capture the existence of such a state for the large variety of superconductors exhibiting it. Here, we show that for two very different thin-film superconductors, amorphous indium oxide and a single crystal of 2H-NbSe2, this metallic state can be eliminated by adequately filtering external radiation. Our results show that the appearance of temperature-independent, metallic-like transport at low temperatures is sufficiently described by the extreme sensitivity of these superconducting films to external perturbations. We relate this sensitivity to the theoretical observation that, in two dimensions, superconductivity is only marginally stable

Coexistence of anomalous field effect and mesoscopic conductance fluctuations in granular aluminium

We perform electrical field effect measurements at 4 K on insulating granular aluminium thin films. When the samples size is reduced below 100 micrometers, reproducible and stable conductance fluctuations are seen as a function of the gate voltage. Our results suggest that these fluctuations reflect the incomplete self-averaging of largely distributed microscopic resistances. We also study the anomalous field effect (conductance dip) already known to exit in large samples and its slow conductance relaxation in the presence of the conductance fluctuations. Within our measurements accuracy, the two phenomena appear to be independent of each other, like two additive contributions to the conductance. We discuss the possible physical meaning of this independence and in particular whether or not this observation is in favor of an electron glass interpretation of slow conductance anomaly relaxations.Comment: 16 pages, 26 figure

On-sky observations with an achromatic hybrid phase knife coronagraph in the visible

CONTEXT: The four-quadrant phase mask stellar coronagraph, introduced by D. Rouan et al., is capable of achieving very high dynamical range imaging and was studied in the context of the direct detection of extra-solar planets. Achromatic four-quadrant phase mask is currently being developed for broadband IR applications. AIMS: We report on laboratory and on-sky tests of a prototype coronagraph in the visible. This prototype, the achromatic hybrid phase knife coronagraph, was derived from the four-quadrant phase mask principle. METHODS: The instrumental setup implementing the coronagraph itself was designed to record the pre- and post-coronagraphic images simultaneously so that an efficient real-time image selection procedure can be performed. We describe the coronagraph and the associated tools that enable robust and repeatable observations. We present an algorithm of image selection that has been tested against the real on-sky data of the binary star HD80081 (* 38 Lyn). RESULTS Although the observing conditions were poor, the efficiency of the proposed method is proven. From this experiment, we derive procedures that can apply to future focal instruments associating adaptive optics and coronagraphy, targeting high dynamic range imaging in astronomy, such as detecting extra-solar planets

Un-reduction

This paper provides a full geometric development of a new technique called un-reduction, for dealing with dynamics and optimal control problems posed on spaces that are unwieldy for numerical implementation. The technique, which was originally concieved for an application to image dynamics, uses Lagrangian reduction by symmetry in reverse. A deeper understanding of un-reduction leads to new developments in image matching which serve to illustrate the mathematical power of the technique.Comment: 25 pages, revised versio

Deformation of grain boundaries in polar ice

The ice microstructure (grain boundaries) is a key feature used to study ice evolution and to investigate past climatic changes. We studied a deep ice core, in Dome Concordia, Antarctica, which records past mechanical deformations. We measured a "texture tensor" which characterizes the pattern geometry and reveals local heterogeneities of deformation along the core. These results question key assumptions of the current models used for dating

Geometric analysis of noisy perturbations to nonholonomic constraints

We propose two types of stochastic extensions of nonholonomic constraints for mechanical systems. Our approach relies on a stochastic extension of the Lagrange-d'Alembert framework. We consider in details the case of invariant nonholonomic systems on the group of rotations and on the special Euclidean group. Based on this, we then develop two types of stochastic deformations of the Suslov problem and study the possibility of extending to the stochastic case the preservation of some of its integrals of motion such as the Kharlamova or Clebsch-Tisserand integrals