179 research outputs found
Mantle formation, coagulation and the origin of cloud/core-shine: II. Comparison with observations
Many dense interstellar clouds are observable in emission in the near-IR,
commonly referred to as "Cloudshine", and in the mid-IR, the so-called
"Coreshine". These C-shine observations have usually been explained with grain
growth but no model has yet been able to self-consistently explain the dust
spectral energy distribution from the near-IR to the submm. We want to
demonstrate the ability of our new core/mantle evolutionary dust model THEMIS
(The Heterogeneous dust Evolution Model at the IaS), which has been shown to be
valid in the far-IR and submm, to reproduce the C-shine observations. Our
starting point is a physically motivated core/mantle dust model. It consists of
3 dust populations: small aromatic-rich carbon grains; bigger core/mantle
grains with mantles of aromatic-rich carbon and cores either made of amorphous
aliphatic-rich carbon or amorphous silicate. We assume an evolutionary path
where these grains, when entering denser regions, may first form a second
aliphatic-rich carbon mantle (coagulation of small grains, accretion of carbon
from the gas phase), second coagulate together to form large aggregates, and
third accrete gas phase molecules coating them with an ice mantle. To compute
the corresponding dust emission and scattering, we use a 3D Monte-Carlo
radiative transfer code. We show that our global evolutionary dust modelling
approach THEMIS allows us to reproduce C-shine observations towards dense
starless clouds. Dust scattering and emission is most sensitive to the cloud
central density and to the steepness of the cloud density profile. Varying
these two parameters leads to changes, which are stronger in the near-IR, in
both the C-shine intensity and profile. With a combination of aliphatic-rich
mantle formation and low-level coagulation into aggregates, we can
self-consistently explain the observed C-shine and far-IR/submm emission
towards dense starless clouds.Comment: Paper accepted for publication in A&A with companion paper "Mantle
formation, coagulation and the origin of cloud/core-shine: I. Dust scattering
and absorption in the IR", A.P Jones, M. Koehler, N. Ysard, E. Dartois, M.
Godard, L. Gavila
Uncertainties in gas kinematics arising from stellar continuum modelling in integral field spectroscopy data: the case of NGC2906 observed with MUSE/VLT
We study how the use of several stellar subtraction methods and line fitting
approaches can affect the derivation of the main kinematic parameters (velocity
and velocity dispersion fields) of the ionized gas component. The target of
this work is the nearby galaxy NGC 2906, observed with the MUSE instrument at
Very Large Telescope. A sample of twelve spectra is selected from the inner
(nucleus) and outer (spiral arms) regions, characterized by different
ionization mechanisms. We compare three different methods to subtract the
stellar continuum (FIT3D, STARLIGHT and pPXF), combined with one of the
following stellar libraries: MILES, STELIB and GRANADA+MILES. The choice of the
stellar subtraction method is the most important ingredient affecting the
derivation of the gas kinematics, followed by the choice of the stellar library
and by the line fitting approach. In our data, typical uncertainties in the
observed wavelength and width of the H\alpha and [NII] lines are of the order
of _rms \sim 0.1\AA\ and _rms \sim 0.2\AA\ (\sim 5
and 10km/s, respectively). The results obtained from the [NII] line seem to be
slightly more robust, as it is less affected by stellar absorption than
H\alpha. All methods considered yield statistically consistent measurements
once a mean systemic contribution
\Delta\bar\lambda=\Delta\bar\sigma=0.2xDelta_{MUSE} is added in quadrature to
the line fitting errors, where \Delta_{MUSE} = 1.1\AA\ \sim 50 km/s denotes the
instrumental resolution of the MUSE spectra. Although the subtraction of the
stellar continuum is critical in order to recover line fluxes, any method
(including none) can be used in order to measure the gas kinematics, as long as
an additional component of 0.2 x Delta_MUSE is added to the error budget.Comment: 20 pages, 14 figure
Mantle formation, coagulation and the origin of cloud/core shine: I. Modelling dust scattering and absorption in the infra-red
Context. The observed cloudshine and coreshine (C-shine) have been explained
in terms of grain growth leading to enhanced scatter- ing from clouds in the J,
H and K photometric bands and the Spitzer IRAC 3.6 and 4.5 {\mu}m bands. Aims.
Using our global dust modelling approach THEMIS (The Heterogeneous dust
Evolution Model at the IaS) we explore the effects of dust evolution in dense
clouds, through aliphatic-rich carbonaceous mantle formation and grain-grain
coagulation. Methods. We model the effects of wide band gap a-C:H mantle
formation and the low-level aggregation of diffuse interstellar medium dust in
the moderately-extinguished outer regions of molecular clouds. Results. The
formation of wide band gap a-C:H mantles on amorphous silicate and amorphous
carbon (a-C) grains leads to a decrease in their absorption cross-sections but
no change in their scattering cross-sections at near-IR wavelengths, resulting
in higher albedos. Conclusions. The evolution of dust, with increasing density
and extinction in the diffuse to dense molecular cloud transition, through
mantle formation and grain aggregation, appears to be a likely explanation for
the observed C-shine.Comment: 12 pages, 15 figures, accepted for publication in A&A along with the
companion paper entitled, Mantle formation, coagulation and the origin of
cloud/core shine: II Comparison with observations, by Ysard et al. (also
accepted for publication in A&A
Television Series Use in Teaching and Learning Professional Ethics in Communication
The work presented here is an exploratory and descriptive study under a
qualitative approach. It purposes was to show the use of television series, as a
means of teaching and learning professional ethics in communication
undergraduate students. Among the results we found two direct areas of impact:
teaching and learning. In the case of teaching, the professor shows an innovative
practice and she realized different ways to improve it as a continuous way to
advance her teaching. In the case of learning, the use of television series
promoted the interest of the students and a significant learning. However, the
most important finding of this study is that the teaching experience has
contributed in the educational process of communicators specifically in ethical
thinking
Factors associated with implementation of the 5A's smoking cessation model
Background: several health organizations have adopted the 5A's brief intervention model (Ask, Advise, Assess, Assist, Arrange), based on evidence-based guidelines for smoking cessation. We examine individual, cognitive, behavioral, and organizational factors associated with the 5A's performance among clinical healthcare workers in Catalonia. We also investigate how these factors interact and potentially predict the implementation of each component of the 5A's. Methods: a cross-sectional survey was conducted among clinical health workers enrolled in an online smoking cessation training course (n = 580). The survey included questions about individual characteristics as well as cognitive, behavioral, and organizational factors previously identified in research. We assessed self-reported performance of the 5A's, assessed on a scale from 0 to 10, and used Multivariate regression to examine factors associated with its performance. Results: the performance means (standard deviation) were moderate for the first 3A's [Ask: 6.4 (3.1); Advise: 7.1 (2.7); Assess: 6.3 (2.8)] and low for the last 2A's [Assist: 4.4 (2.9); Arrange: 3.2 (3.3)]. We observed a high correlation between Assist and Arrange (r = 0.704, p < 0.001). Having positive experiences and feeling competent were positively associated with performing the 5A's model and having organizational support with Assist and Arrange. Personal tobacco use among healthcare workers was negatively associated with Advice and Arrange. Conclusions: our study found that clinical healthcare workers do not perform the 5A's completely. The main barriers identified suggest the need of training and making available practical guidelines in healthcare services. Organizational support is essential for moving towards the implementation of Assist and Arrange
The Need for Laboratory Measurements and Ab Initio Studies to Aid Understanding of Exoplanetary Atmospheres
We are now on a clear trajectory for improvements in exoplanet observations
that will revolutionize our ability to characterize their atmospheric
structure, composition, and circulation, from gas giants to rocky planets.
However, exoplanet atmospheric models capable of interpreting the upcoming
observations are often limited by insufficiencies in the laboratory and
theoretical data that serve as critical inputs to atmospheric physical and
chemical tools. Here we provide an up-to-date and condensed description of
areas where laboratory and/or ab initio investigations could fill critical gaps
in our ability to model exoplanet atmospheric opacities, clouds, and chemistry,
building off a larger 2016 white paper, and endorsed by the NAS Exoplanet
Science Strategy report. Now is the ideal time for progress in these areas, but
this progress requires better access to, understanding of, and training in the
production of spectroscopic data as well as a better insight into chemical
reaction kinetics both thermal and radiation-induced at a broad range of
temperatures. Given that most published efforts have emphasized relatively
Earth-like conditions, we can expect significant and enlightening discoveries
as emphasis moves to the exotic atmospheres of exoplanets.Comment: Submitted as an Astro2020 Science White Pape
Height and timing of growth spurt during puberty in young people living with vertically acquired HIV in Europe and Thailand.
OBJECTIVE: The aim of this study was to describe growth during puberty in young people with vertically acquired HIV. DESIGN: Pooled data from 12 paediatric HIV cohorts in Europe and Thailand. METHODS: One thousand and ninety-four children initiating a nonnucleoside reverse transcriptase inhibitor or boosted protease inhibitor based regimen aged 1-10 years were included. Super Imposition by Translation And Rotation (SITAR) models described growth from age 8 years using three parameters (average height, timing and shape of the growth spurt), dependent on age and height-for-age z-score (HAZ) (WHO references) at antiretroviral therapy (ART) initiation. Multivariate regression explored characteristics associated with these three parameters. RESULTS: At ART initiation, median age and HAZ was 6.4 [interquartile range (IQR): 2.8, 9.0] years and -1.2 (IQR: -2.3 to -0.2), respectively. Median follow-up was 9.1 (IQR: 6.9, 11.4) years. In girls, older age and lower HAZ at ART initiation were independently associated with a growth spurt which occurred 0.41 (95% confidence interval 0.20-0.62) years later in children starting ART age 6 to 10 years compared with 1 to 2 years and 1.50 (1.21-1.78) years later in those starting with HAZ less than -3 compared with HAZ at least -1. Later growth spurts in girls resulted in continued height growth into later adolescence. In boys starting ART with HAZ less than -1, growth spurts were later in children starting ART in the oldest age group, but for HAZ at least -1, there was no association with age. Girls and boys who initiated ART with HAZ at least -1 maintained a similar height to the WHO reference mean. CONCLUSION: Stunting at ART initiation was associated with later growth spurts in girls. Children with HAZ at least -1 at ART initiation grew in height at the level expected in HIV negative children of a comparable age
Primer reporte de Candida auris en Perú
Candida auris is an emerging fungus that has gained great relevance as a global public health problem in a short time. The presence of Candida auris in 3 adult patients admitted to a national hospital of high complexity in the last quarter of 2020 in the midst of the COVID-19 pandemic is reported for the first time in Peru. The patients were hospitalized in the ICU, however, this germ was isolated in only 2 patients while they were hospitalized in the ICU. The patients had various comorbidities and long hospitalization times from admission to having their first culture positive for C. auris. All patients acquired a bacterial nosocomial infection at some point during their hospitalization and received broad-spectrum antibiotics. All isolates were resistant to Fluconazole. The hospital's infection control team reinforced containment measures and the Ministry of Health issued an epidemiological alert.Candida auris es un hongo emergente que ha cobrado en corto tiempo gran relevancia como problema de salud pública mundial. Se reporta por primera vez en el Perú la presencia de Candida auris en 3 pacientes adultos internados en un hospital nacional de alta complejidad en el último trimestre del año 2020 en plena pandemia de COVID-19. Los pacientes fueron hospitalizados en UCI, sin embargo, solo en 2 pacientes se aisló dicho germen mientras estaban hospitalizados en UCI. Los pacientes tenían varias comorbilidades y tiempos prolongados de hospitalización desde su admisión hasta tener su primer cultivo positivo a C. auris. Todos los pacientes adquirieron una infección nosocomial bacteriana en algún momento de su hospitalización y recibieron antibióticos de amplio espectro. Todas las cepas aisladas eran resistentes a Fluconazol. El equipo de control de infecciones del hospital reforzó las medidas de contención y el Ministerio de Salud emitió una alerta epidemiológica
Synaptic Proteins Linked to HIV-1 Infection and Immunoproteasome Induction: Proteomic Analysis of Human Synaptosomes
Infection of the central nervous system with human immunodeficiency virus type 1 (HIV-1) can produce morphological changes in the neocortical synaptodendritic arbor that are correlated with neurocognitive impairment. To determine whether HIV-1 infection influences the protein composition of human synapses, a proteomic study of isolated nerve endings was undertaken. Synaptosomes from frontal neocortex were isolated using isopyknic centrifugation from 19 human brain specimens. Purity and enrichment were assessed by measuring pre- and postsynaptic protein markers. Two-dimensional polyacrylamide gel electrophoresis and matrix-assisted laser desorption ionization time-of-flight mass spectrometry was used to screen for proteins differentially expressed in HIV/AIDS. The concentrations of 31 candidate protein spots were potentially abnormal in HIV-infected decedents with HIV encephalitis and/or increased expression of immunoproteasome subunits. Immunoblots showed that the concentration of some of them was related to HIV-1 infection of the brain and immunoproteasome (IPS) induction. Synapsin 1b and stathmin were inversely related to brain HIV-1 load; 14-3-3ζ and 14-4-4ε proteins were higher in subjects with HIV-1 loads. Perturbed synaptosome proteins were linked with IPS subunit composition, and 14-3-3ζ was histologically colocalized with IPS subunits in stained neocortical neurons. Proteomics illustrates that certain human proteins within the synaptic compartment are involved with changes in the synaptodendritic arbor and neurocognitive impairment in HIV-1-infected people
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