150 research outputs found

    Phenolic metabolites of anthocyanins modulate mechanisms of endothelial function

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    Anthocyanins are reported to have vascular bioactivity, however their mechanisms of action are largely unknown. Evidence suggests that anthocyanins modulate endothelial function, potentially by increasing nitric oxide (NO) synthesis, or enhancing NO bioavailability. This study compared the activity of cyanidin-3-glucoside, its degradation product protocatechuic acid, and phase II metabolite, vanillic acid. Production of NO and superoxide and expression of endothelial NO synthase (eNOS), NADPH oxidase (NOX), and heme oxygenase-1 (HO-1) were established in human vascular cell models. Nitric oxide levels were not modulated by the treatments, although eNOS was upregulated by cyanidin-3-glucoside, and superoxide production was decreased by both phenolic acids. Vanillic acid upregulated p22phox mRNA but did not alter NOX protein expression, although trends were observed for p47phox downregulation and HO-1 upregulation. Anthocyanin metabolites may therefore modulate vascular reactivity by inducing HO-1 and modulating NOX activity, resulting in reduced superoxide production and improved NO bioavailability

    The pseudodichotomous Dasya sylviae sp. nov. (Delesseriaceae, Ceramiales) from 60–90 m mesophotic reefs off Bermuda

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    The red alga Dasya sylviae C.W.Schneid., M.M.Cassidy & G.W.Saunders sp. nov . is described from mesophotic depths of 60–90 m off Bermuda. Genetic sequences (COI-5P, rbc L) and morphological characteristics show that this species is distinct from other known pseudodichotomous species of Dasya . Of ten current species in the genus reported from Bermuda, only three, D. collinsiana M.Howe, D. cryptica C.W.Schneid., Quach & C.E.Lane and D. punicea (Zanardini) Menegh., share the overall pattern of pseudodichotomous branching in their axes; however, key morphological features easily distinguish them from D. sylviae sp. nov. The species most similar in habit to D. sylviae sp. nov. is D. crouaniana J.Agardh (type locality West Indies), but it bears shorter pseudolateral branches, and broader and longer tetrasporangial stichidia than the new species. Unique among the species of Dasya , D. sylviae sp. nov. lacks post-sporangial cover cells in tetrasporangial stichidia

    FCIC Memo from Gary Cohen and Cassidy Waskowicz to Commissioners Regarding Quotation and Interview Objections

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    Waskowicz Email to Knaus re Use of DeMarco Quote

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    FCIC memo of staff interview with John Cassidy, The New Yorker

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    Graphic Flash: A Collaboration of Writing, Arts and Media

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    Graphic Flash is an interdisciplinary collaborative project involving almost 100 students at SUNY Oswego. The process begins with a flash fiction story produced by advanced creative writers. These narratives are given to students in digital illustration, filmmaking students, and music students who come up with their own artistic interpretations of the stories. All of the student artworks are then brought together into a single Graphic Flash application. The app, designed by SUNY Oswego students studying digital publication, creates a space for all of the different art forms to exist aesthetically together in one location. The interactivity of the app allows the audience to read stories or hear the authors read them; to view an illustration; to listen to music based on the narrative themes; to watch short films. The resultant experience invites the audience to experience the versatility and depth of a single artistic idea explored creatively through the prism of multiple artistic lenses. SUNY Oswego students representing the various disciplines involved in Graphic Flash will speak to their creative processes and the ways they introduced their personal vision into the shared practices. Discussion from panelists will likely also include topics like ekphrasis (art responding to art), adaptation, the role of professionalism in writing and the arts, the role of taste in collaborative work, and arts in the digital age
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