429 research outputs found
Intelligence and Responsibility
The paper deals with the problems of responsibility in modern intelligence agencies. The paper deals with the problem by briefly addressing modern intelligence activities and types of agencies, followed by a central chapter of identifying the challenges of conducting intelligence inside the democracies, and how to legitimize such activities. To identify whether such legitimization is found in today's intelligence organization, three case studies are investigated. The cases are the United States, the United Kingdom and Denmark
The Rabbits\u27 Wedding
32 unnumbered pages : color illustrations ; 32 cm. Double, illustrated title page. Printed in the United States of America --Title page verso. Two little rabbits, one white and one black, decide they want to remain friends forever, so they marry each other in a forest wedding. Illustrated book jacket, some tears and paper wear, loss. Case binding. Walter Lorraine Fund.https://digitalcommons.risd.edu/specialcollections_books_illustration/1004/thumbnail.jp
Associations between breast cancer survivorship and adverse mental health outcomes: A matched population-based cohort study in the United Kingdom.
BACKGROUND: Breast cancer is the most common cancer diagnosed in women globally, and 5-year net survival probabilities in high-income countries are generally >80%. A cancer diagnosis and treatment are often traumatic events, and many women struggle to cope during this period. Less is known, however, about the long-term mental health impact of the disease, despite many women living several years beyond their breast cancer and mental health being a major source of disability in modern societies. The objective of this study was to quantify the risk of several adverse mental health-related outcomes in women with a history of breast cancer followed in primary care in the United Kingdom National Health Service, compared to similar women who never had cancer. METHODS AND FINDINGS: We conducted a matched cohort study using data routinely collected in primary care across the UK to quantify associations between breast cancer history and depression, anxiety, and other mental health-related outcomes. All women with incident breast cancer in the Clinical Practice Research Datalink (CPRD) GOLD primary care database between 1988 and 2018 (N = 57,571, mean = 62 ± 14 years) were matched 1:4 to women with no prior cancer (N = 230,067) based on age, primary care practice, and eligibility of the data for linkage to hospital data sources. Cox models were used to estimate associations between breast cancer survivorship and each mental health-related outcome, further adjusting for diabetes, body mass index (BMI), and smoking and drinking status at baseline. Breast cancer survivorship was positively associated with anxiety (adjusted hazard ratio (HR) = 1.33; 95% confidence interval (CI): 1.29-1.36; p < 0.001), depression (1.35; 1.32-1.38; p < 0.001), sexual dysfunction (1.27; 1.17-1.38; p < 0.001), and sleep disorder (1.68; 1.63-1.73; p < 0.001), but not with cognitive dysfunction (1.00; 0.97-1.04; p = 0.88). Positive associations were also found for fatigue (HR = 1.28; 1.25-1.31; p < 0.001), pain (1.22; 1.20-1.24; p < 0.001), receipt of opioid analgesics (1.86; 1.83-1.90; p < 0.001), and fatal and nonfatal self-harm (1.15; 0.97-1.36; p = 0.11), but CI was wide, and the relationship was not statistically significant for the latter. HRs for anxiety and depression decreased over time (p-interaction <0.001), but increased risks persisted for 2 and 4 years, respectively, after cancer diagnosis. Increased levels of pain and sleep disorder persisted for 10 years. Younger age was associated with larger HRs for depression, cognitive dysfunction, pain, opioid analgesics use, and sleep disorders (p-interaction <0.001 in each case). Limitations of the study include the potential for residual confounding by lifestyle factors and detection bias due to cancer survivors having greater healthcare contact. CONCLUSIONS: In this study, we observed that compared to women with no prior cancer, breast cancer survivors had higher risk of anxiety, depression, sleep problems, sexual dysfunction, fatigue, receipt of opioid analgesics, and pain. Relative risks estimates tended to decrease over time, but anxiety and depression were significantly increased for 2 and 4 years after breast cancer diagnosis, respectively, while associations for fatigue, pain, and sleep disorders were elevated for at least 5-10 years after diagnosis. Early diagnosis and increased awareness among patients, healthcare professionals, and policy makers are likely to be important to mitigate the impacts of these raised risks
Are rates of school suspension higher in socially disadvantaged neighbourhoods? An Australian study
Issue addressed: Health promotion with adolescents spans many contexts including schools. Income and its distribution, education and social exclusion are key social determinants of health. Exclusionary school policies such as school suspension contribute to exclusion, increase the likelihood of school dropout (reducing educational and subsequent employment opportunities), and negatively impact on student wellbeing. Often excluded students are from socio-economically disadvantaged areas. This paper examines associations between area level socio-economic status (SES) and school suspension in Australian students. Methods: Students (8,028) in years 6 (n = 4393) and 8 (n = 3635) completed a comprehensive social development survey administered in schools in 30 socio-economically stratified communities in 2006.Results: Associations between area level SES and school suspension were found. Relative to students in the lowest SES quartile communities, students in mid level and high SES had lower suspension rates. These effects remained after controlling for antisocial behaviour, gender, age and the established risk factors of poor family management, interaction with antisocial peers and academic failure. Conclusions: Students living in low SES areas are exposed to higher rates of school suspension, at similar levels of adjustment problems. Assisting schools, particularly those with disadvantaged students, to foster school engagement is essential for schools committed to health promotion
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Associations between breast cancer survivorship and adverse mental health outcomes: A matched population-based cohort study in the United Kingdom
Background: Breast cancer is the most common cancer diagnosed in women globally, and 5-year net survival probabilities in high-income countries are generally >80%. A cancer diagnosis and treatment are often traumatic events, and many women struggle to cope during this period. Less is known, however, about the long-term mental health impact of the disease, despite many women living several years beyond their breast cancer and mental health being a major source of disability in modern societies. The objective of this study was to quantify the risk of several adverse mental health–related outcomes in women with a history of breast cancer followed in primary care in the United Kingdom National Health Service, compared to similar women who never had cancer. Methods and findings: We conducted a matched cohort study using data routinely collected in primary care across the UK to quantify associations between breast cancer history and depression, anxiety, and other mental health–related outcomes. All women with incident breast cancer in the Clinical Practice Research Datalink (CPRD) GOLD primary care database between 1988 and 2018 (N = 57,571, mean = 62 ± 14 years) were matched 1:4 to women with no prior cancer (N = 230,067) based on age, primary care practice, and eligibility of the data for linkage to hospital data sources. Cox models were used to estimate associations between breast cancer survivorship and each mental health–related outcome, further adjusting for diabetes, body mass index (BMI), and smoking and drinking status at baseline. Breast cancer survivorship was positively associated with anxiety (adjusted hazard ratio (HR) = 1.33; 95% confidence interval (CI): 1.29–1.36; p < 0.001), depression (1.35; 1.32–1.38; p < 0.001), sexual dysfunction (1.27; 1.17–1.38; p < 0.001), and sleep disorder (1.68; 1.63–1.73; p < 0.001), but not with cognitive dysfunction (1.00; 0.97–1.04; p = 0.88). Positive associations were also found for fatigue (HR = 1.28; 1.25–1.31; p < 0.001), pain (1.22; 1.20–1.24; p < 0.001), receipt of opioid analgesics (1.86; 1.83–1.90; p < 0.001), and fatal and nonfatal self-harm (1.15; 0.97–1.36; p = 0.11), but CI was wide, and the relationship was not statistically significant for the latter. HRs for anxiety and depression decreased over time (p-interaction <0.001), but increased risks persisted for 2 and 4 years, respectively, after cancer diagnosis. Increased levels of pain and sleep disorder persisted for 10 years. Younger age was associated with larger HRs for depression, cognitive dysfunction, pain, opioid analgesics use, and sleep disorders (p-interaction <0.001 in each case). Limitations of the study include the potential for residual confounding by lifestyle factors and detection bias due to cancer survivors having greater healthcare contact. Conclusions: In this study, we observed that compared to women with no prior cancer, breast cancer survivors had higher risk of anxiety, depression, sleep problems, sexual dysfunction, fatigue, receipt of opioid analgesics, and pain. Relative risks estimates tended to decrease over time, but anxiety and depression were significantly increased for 2 and 4 years after breast cancer diagnosis, respectively, while associations for fatigue, pain, and sleep disorders were elevated for at least 5–10 years after diagnosis. Early diagnosis and increased awareness among patients, healthcare professionals, and policy makers are likely to be important to mitigate the impacts of these raised risks
The Evolution of Mass-size Relation for Lyman Break Galaxies From z=1 to z=7
For the first time, we study the evolution of the stellar mass-size relation
for star-forming galaxies from z ~ 4 to z ~ 7 from Hubble-WFC3/IR camera
observations of the HUDF and Early Release Science (ERS) field. The sizes are
measured by determining the best fit model to galaxy images in the rest-frame
2100 \AA \ with the stellar masses estimated from SED fitting to rest-frame
optical (from Spitzer/IRAC) and UV fluxes. We show that the stellar mass-size
relation of Lyman-break galaxies (LBGs) persists, at least to z ~ 5, and the
median size of LBGs at a given stellar mass increases towards lower redshifts.
For galaxies with stellar masses of 9.5<Log(M*/Msun)<10.4 sizes evolve as
. This evolution is very similar for galaxies with lower
stellar masses of 8.6<Log(M*/Msun)<9.5 which is , in agreement with simple theoretical galaxy formation
models at high z. Our results are consistent with previous measurements of the
LBGs mass-size relation at lower redshifts (z ~ 1-3).Comment: Accepted for publication in The Astrophysical Journal Letter
Application of machine learning to microseismic event detection in distributed acoustic sensing data
The stellar mass structure of massive galaxies from z=0 to z=2.5; surface density profiles and half-mass radii
We present stellar mass surface density profiles of a mass-selected sample of
177 galaxies at 0.5 < z < 2.5, obtained using very deep HST optical and
near-infrared data over the GOODS-South field, including recent CANDELS data.
Accurate stellar mass surface density profiles have been measured for the first
time for a complete sample of high-redshift galaxies more massive than 10^10.7
M_sun. The key advantage of this study compared to previous work is that the
surface brightness profiles are deconvolved for PSF smoothing, allowing
accurate measurements of the structure of the galaxies. The surface brightness
profiles account for contributions from complex galaxy structures such as rings
and faint outer disks. Mass profiles are derived using radial rest-frame u-g
color profiles and a well-established empirical relation between these colors
and the stellar mass-to-light ratio. We derive stellar half-mass radii from the
mass profiles, and find that these are on average ~25% smaller than rest-frame
g band half-light radii. This average size difference of 25% is the same at all
redshifts, and does not correlate with stellar mass, specific star formation
rate, effective surface density, Sersic index, or galaxy size. Although on
average the difference between half-mass size and half-light size is modest,
for approximately 10% of massive galaxies this difference is more than a factor
two. These extreme galaxies are mostly extended, disk-like systems with large
central bulges. These results are robust, but could be impacted if the central
dust extinction becomes high. ALMA observations can be used to explore this
possibility. These results provide added support for galaxy growth scenarios
wherein massive galaxies at these epochs grow by accretion onto their outer
regions.Comment: 11 pages, 8 figures, 3 tables, accepted for publication in Ap
The Star Formation Rate-Density Relation at 0.6<z<0.9 and the Role of Star Forming Galaxies
We study the star formation rates (SFRs) of galaxies as a function of local
galaxy density at 0.6<z<0.9. We used a low-dispersion prism in IMACS on the
6.5-m Baade (Magellan I) telescope to obtain spectra and measured redshifts to
a precision of sigma_z/(1+z)=1% for galaxies with z<23.3 AB mag. We utilized a
stellar mass-limited sample of 977 galaxies above M>1.8x10^{10} Msun to conduct
our main analysis. With three different SFR indicators, (1) Spitzer MIPS
24-micron imaging, (2) SED fitting, and (3) [OII]3727 emission, we find the
median specific SFR (SSFR) and SFR to decline from the low-density field to the
cores of groups and a rich cluster. For the SED and [OII] based SFRs, the
decline in SSFR is roughly an order of magnitude while for the MIPS based SFRs,
the decline is a factor of ~4. We find approximately the same magnitude of
decline in SSFR even after removing the sample of galaxies near the cluster.
Galaxies in groups and a cluster at these redshifts therefore have lower star
formation (SF) activity than galaxies in the field, as is the case at z~0. We
investigated whether the decline in SFR with increasing density is caused by a
change in the proportion of quiescent and star forming galaxies (SFGs) or by a
decline in the SFRs of SFGs. Using the rest-frame U-V and V-J colors to
distinguish quiescent galaxies from SFGs we find the fraction of quiescent
galaxies increases from ~32% to 79% from low to high density. In addition, we
find the SSFRs of SFGs, selected based on U-V and V-J colors, to decline with
increasing density by factors of ~5-6 for the SED and [OII] based SFRs. The
MIPS based SSFRs for SFGs decline with a shallower slope. The order of
magnitude decline in the SSFR-density relation at 0.6<z<0.9 is therefore driven
by both a combination of declining SFRs of SFGs as well as a changing mix of
SFGs and quiescent galaxies [ABRIDGED].Comment: 21 pages, 15 figures, 2 tables, resubmitted to ApJ after addressing
referee comment
3D-HST: A wide-field grism spectroscopic survey with the Hubble Space Telescope
We present 3D-HST, a near-infrared spectroscopic Treasury program with the
Hubble Space Telescope for studying the processes that shape galaxies in the
distant Universe. 3D-HST provides rest-frame optical spectra for a sample of
~7000 galaxies at 1<z<3.5, the epoch when 60% of all star formation took place,
the number density of quasars peaked, the first galaxies stopped forming stars,
and the structural regularity that we see in galaxies today must have emerged.
3D-HST will cover 3/4 (625 sq.arcmin) of the CANDELS survey area with two
orbits of primary WFC3/G141 grism coverage and two to four parallel orbits with
the ACS/G800L grism. In the IR these exposure times yield a continuum
signal-to-noise of ~5 per resolution element at H~23.1 and a 5sigma emission
line sensitivity of 5x10-17 erg/s/cm2 for typical objects, improving by a
factor of ~2 for compact sources in images with low sky background levels. The
WFC3/G141 spectra provide continuous wavelength coverage from 1.1-1.6 um at a
spatial resolution of ~0."13, which, combined with their depth, makes them a
unique resource for studying galaxy evolution. We present the preliminary
reduction and analysis of the grism observations, including emission line and
redshift measurements from combined fits to the extracted grism spectra and
photometry from ancillary multi-wavelength catalogs. The present analysis
yields redshift estimates with a precision of sigma(z)=0.0034(1+z), or
sigma(v)~1000 km/s. We illustrate how the generalized nature of the survey
yields near-infrared spectra of remarkable quality for many different types of
objects, including a quasar at z=4.7, quiescent galaxies at z~2, and the most
distant T-type brown dwarf star known. The CANDELS and 3D-HST surveys combined
will provide the definitive imaging and spectroscopic dataset for studies of
the 1<z<3.5 Universe until the launch of the James Webb Space Telescope.Comment: Replacement reflects version now accepted by ApJS. A preliminary data
release intended to provide a general illustration of the WFC3 grism data is
available at http://3dhst.research.yale.edu
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