Batch to the future: Analyzing timestamp accuracy of high-performance packet I/O engines

Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. V. Moreno, P. M. S. Del Rio, J. Ramos, J. J. Garnica, and J. L. Garcia-Dorado, "Batch to the future: Analyzing timestamp accuracy of high-performance packet I/O engines", IEEE Communications Letters, vol. 16, no. 11, pp. 1888 - 1891, November 2012.Novel packet I/O engines allow capturing traffic at multi-10Gb/s using only-software and commodity-hardware systems. This is achieved thanks to the application of techniques such as batch processing. Nevertheless, this feature involves degradation in the timestamp accuracy, which may be relevant for monitoring purposes. We propose two different approaches to mitigate such effect: a simple algorithm to distribute inter-batch time among the packets composing a batch, and a driver modification to poll NIC buffers avoiding batch processing. Experimental results, using both synthetic and real traffic, show that our proposals allow capturing accurately timestamped traffic for monitoring purposes at multi-10Gb/s rates

Aportes para investigar la enseñanza de la matemática en carreras de ingeniería: las aptitudes analíticas de alumnos que cursan Análisis Matemático I.

Desde hace varios años estamos investigando la Enseñanza de la Matemática en el Nivel Medio, a través de diferentes Proyectos con enfoque constructivista, y con apoyo en la Didáctica de la Matemática de Brusseau y la Ingeniería Didáctica. Actualmente trabajamos también en una mirada sobre la propia práctica en la Universidad, con un Proyecto de Investigación-acción en la Cátedra de Análisis Matemático I. Entendemos que investigar en enseñanza de la matemática implica bucear en aspectos epis- temológicos de la disciplina, centrarse en las estrategias didácticas del Profesor y en el Curriculum. Pero ampliar el campo de estudio hacia el alumno investigando las dificultades y capacidades evidenciadas por los estudiantes también puede tornarse un aporte valioso en el momento de investigar lo que sucede con la enseñanza de la disciplina; por ejemplo, analizar las competencias de los alumnos en relación a accio- nes, operaciones y habilidades requeridas en el proceso de aprendizaje de la Matemática. Por lo tanto en este Proyecto hemos incluido la indagación de las Aptitudes analíticas de los alumnos y para ello imple- mentamos una Prueba estandarizada: el Test WASI (Whimbey Analytical Skils Inventory) o Inventario analítico de las Aptitudes Whimbey. Aportamos aquí las primeras lecturas de los resultados

Modelo del proceso de innovación mediante factores dinámicos y de transferencia

Abstract: From the outset, innovation models have considered technology and the market as their main pillars, gradually incorporating human, social and cultural factors. However, a new model is needed that considers these factors in an integral way as part of a new management of the innovation process. The objective of this research is to propose a model that identifies the most significant innovation factors for the companies. The object of study was the sector of ceramic tiles in Tlaxcala Mexico. The methodology consisted of an analysis of different models of innovation published and recognized to identify the most significant factors. Subsequently, an assessment of the perception was carried out through an evaluation instrument and an inferential statistics. The results obtained reveal a significant average perception towards the proposed factors, concluding that companies need to consider these factors in a comprehensive way to strengthen their innovation process.Resumen: Desde un principio, los modelos de innovación han considerado a la tecnología y al mercado como sus pilares principales, incorporando paulatinamente, factores humanos, sociales y culturales. Sin embargo, se requiere de un modelo que los considere de forma integral como parte de una nueva gestión del proceso de innovación. El objetivo de esta investigación es proponer un modelo que identifique los factores de innovación más significativos para las empresas, tomando como objeto de estudio el sector de recubrimientos cerámicos en Tlaxcala México. La metodología consistió en analizar diversos modelos publicados y reconocidos para identificar los factores más significativos. Posteriormente, se realizó un diagnóstico de la percepción por medio de un instrumento de evaluación y de un análisis inferencial. Los resultados revelaron una percepción promedio significativa con respecto a los factores propuestos, concluyendo que las empresas deben considerarlos de una forma integral para fortalecer sus procesos de innovación

Switching TNF antagonists in patients with chronic arthritis: An observational study of 488 patients over a four-year period

The objective of this work is to analyze the survival of infliximab, etanercept and adalimumab in patients who have switched among tumor necrosis factor (TNF) antagonists for the treatment of chronic arthritis. BIOBADASER is a national registry of patients with different forms of chronic arthritis who are treated with biologics. Using this registry, we have analyzed patient switching of TNF antagonists. The cumulative discontinuation rate was calculated using the actuarial method. The log-rank test was used to compare survival curves, and Cox regression models were used to assess independent factors associated with discontinuing medication. Between February 2000 and September 2004, 4,706 patients were registered in BIOBADASER, of whom 68% had rheumatoid arthritis, 11% ankylosing spondylitis, 10% psoriatic arthritis, and 11% other forms of chronic arthritis. One- and two-year drug survival rates of the TNF antagonist were 0.83 and 0.75, respectively. There were 488 patients treated with more than one TNF antagonist. In this situation, survival of the second TNF antagonist decreased to 0.68 and 0.60 at 1 and 2 years, respectively. Survival was better in patients replacing the first TNF antagonist because of adverse events (hazard ratio (HR) for discontinuation 0.55 (95% confidence interval (CI), 0.34-0.84)), and worse in patients older than 60 years (HR 1.10 (95% CI 0.97-2.49)) or who were treated with infliximab (HR 3.22 (95% CI 2.13-4.87)). In summary, in patients who require continuous therapy and have failed to respond to a TNF antagonist, replacement with a different TNF antagonist may be of use under certain situations. This issue will deserve continuous reassessment with the arrival of new medications. © 2006 Gomez-Reino and Loreto Carmona; licensee BioMed Central Ltd