La contemplación romántica medieval. La vida estética de Beethoven como posibilidad de humanización

En este trabajo se revisa de forma sucinta la historia del concepto estética, así como la aparición de otras nociones, actores y sucesos que influirán en la comprensión del término y sus alcances. Existen varias categorías que requieren un profundo análisis, pues, ya sea de manera expresa o tácita, llevan el apellido de estética. Dichas categorías las encontraremos claramente enunciadas tanto en la Ilustración como en el Romanticismo. El análisis de las categorías que se proponen en este ensayo, servirá para una mejor comprensión del desarrollo del concepto estética en su versión ilustrada y romántica. Uno de los objetivos del ensayo es revisar la transición que el concepto de estética sufrió entre la llamada “experiencia estética” (Ilustración) y la “contemplación estética” (Romanticismo), para reconocer la conexión de esta última con la noción medieval de “mística”, la cual se acerca al despliegue del sentimiento que, sobre la razón, exaltarán los románticos como parte fundamental de la experiencia (contemplación) estética. De lo anterior, se desprende el planteamiento de la hipótesis de que la estética en el Romanticismo ha de entenderse como una contemplación al estilo medieval, cercana a la visión mística de dicho contexto. Por último, y como parte central de este ensayo, se revisa la figura de Ludwig Van Beethoven como artista y músico que vivió, que percibió y sintió, es decir, contempló, de esta manera romántica medieval, mística y limpia, que lo transformó para profundizar y sentir la vida desde ahí y para poder producir y crear la obra que nos legó

Diseño y optimización de las superficies aerodinámicas de un cohete subsónico

Con este trabajo se ha conseguido diseñar tanto aerodinámicamente como estructuralmente las aletas y la punta de un cohete en su vuelo subsónico. Se ha partido de unas condiciones impuestas de diseño y se han elaborado, a través de programas de simulación, una serie de cálculos para determinar cómo debían ser las formas previamente citadas. No solo eso, sino que además se ha comprobado que estructuralmente resisten y se ha dejado abierta la posibilidad de una continuación de la investigación relacionada con el análisis dinámico

Hipercoagulabilidad, foramen oval permeable e ictus criptogénico

[ES]La hipertensión arterial refractaria (HTA-R) se define como aquellas situaciones en las que no es posible alcanzar el objetivo de presión arterial en pacientes que han realizado modificaciones en el estilo de vida y están tomando las dosis adecuadas de una terapia farmacológica de 3 medicamentos incluyendo un diurético. Hasta el momento esta entidad ha sido abordada como una falta de cumplimiento o mala praxis, sin embargo parte de esta resistencia podría determinarse a nivel genético Estudiamos en 50 pacientes HTA-R, 234 hipertensos controlados y 112 sujetos sin hipertensión los polimorfismos genéticos -786C mayor que T NOS3, 984G mayor que T, 35G mayor que C PPARG, 8473C mayor que T PTGS2, 825C mayor que T GNB, 1947G mayor que A COMT, GSTM1, GSTT1, 313A mayor que G GSTP1. Encontramos diferencias entre HTA-R e hipertensos controlados, el alelo C de -786C mayor que T NOS3 es más frecuente en HTA-R con respecto a los controlados (p = 0,014 OR 2,32 (1,17-4,63)), el alelo T de 825C mayor que T GNB3 se asocia a hipertensión con respecto a sujetos control (p = 0,016 OR 1,4 (1,04-1.91)), y a hipertensión controlado con respecto a HTA-R (p = 0,035 OR 0.6 (0.38-0.96), el alelo nulo de GSTM aumenta la susceptibilidad de desarrollar HTA-R con respecto a hipertensión controlada p = 0,025 OR 2,029 (1,08-3,78)), y la presencia de GSTT se relaciona con hipertensión con respecto a los controles (p = 0,040 OR= 1,68 (1,021-2,77)) Por tanto existen diferencias en la distribución de los genotipos de los genes seleccionados en este trabajo entre pacientes con hipertensión arterial refractaria, hipertensión controlada y sujetos no hipertensos, lo que sugiere que el origen de la hipertensión arterial y su respuesta al tratamiento se encuentran, al menos en parte, condicionadas a nivel genético

Manuel de Elías: Hermenéutica de su conciencia ceadora y experiencia formativa

Tesis doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Formación de Profesorado y Educación. Departamento de Didáctica y Teoría de la Educación. Fecha de lectura: 22-09-2017La investigación estudia cuestiones específicas del proceso creativo del reconocido compositor y director de orquesta Manuel de Elías. Sus objetivos son tres: el primero es profundizar en la comprensión del proceso creativo de Manuel de Elías. El segundo es indagar, desprender y sistematizar implicaciones de la creatividad del autor para la formación de otros compositores. El tercero es validar y transferir implicaciones formativas para el proceso creativo de compositores concretos. La metodología de la investigación responde a un estudio de caso, de corte biográfico, seleccionado por su reconocido potencial creativo. El enfoque epistémico es hermenéutico, centrado en la experiencia estética, intuitiva y anímica aplicada a la composición musical del autor y recorrida, desde su ser-en-el-mundo, hasta su exposición e interpretación de estados de conciencia creadores en el proceso de composición de su obra. Se trabajará con una selección de compositores latinoamericanos –que actuarán a la vez como expertos y participantes del estudio-, que valorarán y algunos validarán la bondad de las implicaciones de las observaciones hechas en Manuel de Elías y la transferibilidad formativa, en el campo de su formación mediante creatividad para la composición musical. Las conclusiones apuntan a una riqueza extraordinaria del proceso creativo en la composición musical de Manuel de Elías, hasta cierto punto comprensible, objetivable y transferible a la formación mediante creatividad de otros compositores, específicamente relacionada con el enriquecimiento de la experiencia estética. Se concluye con que la experiencia del universo anímico y de invención de Manuel de Elías, desarrollada en torno a su proceso creativo compositor, puede ser un referente pedagógico facilitador de una identificación afectiva importante para la formación de otros compositores

Information about Human Evolution: An Analysis of News Published in Communication Media in Spanish between 2015 and 2017

The present study examines a sample of 220 pieces of news related to human evolution, written in Spanish and published over a period of two years, both in digital and print media. The aim of this study is to assess the rigor and coherence of the information in the news in our sample with scientific knowledge on the theory of evolution. To this end, errors and the incorrect use of concepts related to biological evolution are identified, classified according to criteria resulting from the review of previous studies, and finally, the frequency of errors identified in news published in print media is compared with that identified in digital media. The results presented allow us to highlight the significantly high frequency of errors in the news analyzed and the most frequent error categories. Results are discussed within the frame of the important role that scientific journalism plays in the processes of knowledge dissemination, in this case, related to human evolution.This research was funded by the University of the Basque Country through the project PES20/49

Probiotic effects of Bacillus spp. bacteria on the survival and growth of white shrimp (Litopenaeus vannamei) in 30 and 40 g/lit salinities

The probiotic effects of Bacillus spp. bacteria on the growth and survival rate of Litopenaeus vannamei in 30 and 40 g, salinities was investigated. We conducted the experiment in Bandargah Research Station, Bushehr province during 45 days. Four treatments with three replicates, and two controls were used and probiotic powder, dissolved in water along with the growth stage pellet was applied in 3O ppt and 4O ppt salinities. The control treatments were only fed by the growth stage pellet in 3O ppt and 4O ppt salinities. The results revealed that growth and survival rate of treatment groups in 3O ppt salinity exposed to the probiotic powder were higher than those of the controls without increasing probiotic powder (P0.05). Survival rate of the treatment groups in 4O ppt salinity was significantly higher than those of the control (P<0.05). Also, the results indicated that growth and survival factors of the treatment groups in 3O ppt salinity in comparison with those of the control in 4O ppt salinity were significantly higher. We conclude that addition of Bacillus spp. bacteria to 3O ppt salinity together with application of growth stage pellets to white shrimp, Litopenaeus vannaiiiei, could be very useful in comparison with 4O ppt salinity. The results of this study were obtained through ANOVA and LSD tests

Localizing Object-level Shape Variations with Text-to-Image Diffusion Models

Text-to-image models give rise to workflows which often begin with an exploration step, where users sift through a large collection of generated images. The global nature of the text-to-image generation process prevents users from narrowing their exploration to a particular object in the image. In this paper, we present a technique to generate a collection of images that depicts variations in the shape of a specific object, enabling an object-level shape exploration process. Creating plausible variations is challenging as it requires control over the shape of the generated object while respecting its semantics. A particular challenge when generating object variations is accurately localizing the manipulation applied over the object's shape. We introduce a prompt-mixing technique that switches between prompts along the denoising process to attain a variety of shape choices. To localize the image-space operation, we present two techniques that use the self-attention layers in conjunction with the cross-attention layers. Moreover, we show that these localization techniques are general and effective beyond the scope of generating object variations. Extensive results and comparisons demonstrate the effectiveness of our method in generating object variations, and the competence of our localization techniques.Comment: ICCV 2023. Project page at https://orpatashnik.github.io/local-prompt-mixing

Effect of hot-water extract of brown seaweed Sargassum glaucescens via immersion route on immune responses of Fenneropenaeus indicus

The development of shrimp aquaculture, in spite of its global necessity, is largely at stake as significant ecological and pathological problems are increasing in the vast majority of the shrimp producing countries. Shrimp immunology is a key element in establishing strategies for controlling diseases in shrimp aquaculture. The total haemocyte count (THC), differential haemocyte count (DHC), total plasma protein (TPP), Phagocytic activity (PA), bacterial clearance efficiency (BCE) and bactericidal activity (BE) were examined when the F. indicus shrimps (11.32±1.20 g) were immersed in seawater (39 ppt and 25 ± 1 ºC) containing hot-water extracts of brown alga Sargassum glaucescens at 100, 300 and 500 mg/l. These parameters increased significantly (p < 0.05) when the shrimp were immersed in seawater containing hot-water extracts at 100 mg/l after 3h and 300 and 500 mg/l after 2 h. F. indicus shrimps that were immersed in hot-water extracts at 300 and 500 mg/l had increased phagocytic activity and clearance efficiency to Vibrio spp. after 2 hours. But bactericidal activity increased significantly after 1 hour in the same concentrations

Relationship between asthma and related factors of birth

BACKGROUND: Asthma is the most common chronic disease of childhood that causes disturbance in the physical, emotional, mental health, and different information has been mentioned on its risk factors, including factors associated with birth. Therefore, in this study, the relationship between children asthma and factors associated with birth was studied. METHODS: This case-control study was performed on 50 children with asthma as the case group and 150 children hospitalized without asthma as the control group (after matched for age and sex) in an age range of 4-14 years old. Information required on factors affecting asthma was recorded for both groups. Data analysis was performed using SPSS for Windows software. RESULTS: The results of this study showed that the majority of children in the case group were males born through cesarean operation (C-section). A significant difference was seen between two groups in terms of factors such as preterm [odds ratio (OR) = 3.27, confidence interval (CI) 95% = 1.57-6.81] and family history of asthma (OR = 8.50, CI 95% = 4.10-17.60). Regression model of relational variables with asthma show that the family history of asthma was most effective determinant on birth-related factors of asthma. CONCLUSION: The findings of this study showed that positive family history of the disease and premature-birth in infant correlates significantly and directly with asthma occurrence in children. Thus, it is recommended to make further follow-ups in providing prenatal care and early diagnosis of the disease

Two-year clinical outcome from the Iberian registry patients after left atrial appendage closure

AIMS: The aim of this study was to observe the percentage of thromboembolic and haemorrhagic events over a 2-year follow-up in patients with non-valvular atrial fibrillation (NVAF) undergoing closure of the left atrial appendage (LAA) with an occlusion device. Observed events and CHADS2 (congestive heart failure, hypertension, age, diabetes, stroke history), CHA2DS2-VASc (also adding: vascular disease and sex) and HAS-BLED (hypertension, abnormal liver/renal function, stroke history, bleeding predisposition, labile international normalised ratios, elderly, drugs/alcohol use)-predicted events were compared. METHODS: LAA closure with an occlusion device was performed in 167 NVAF patients contraindicated for oral anticoagulants and recruited from 12 hospitals between 2009 and 2013. At least two transoesophageal echocardiograms were performed in the first 6 months postimplantation. Antithrombotics included clopidogrel and aspirin. Patients were monitored for death, stroke, major and relevant bleeding and hospitalisation for concomitant conditions. Mean age was 74.68±8.58, median follow-up was 24 months, 5.38% had intraoperative complications and implantation was successful in 94.6% of subjects. Mortality during follow-up was 10.8%, mostly (9.5%) non-cardiac related. Bleeding occurred in 10.1% of subjects, 5.7% major and 4.4% minor though relevant, and 4.4% suffered stroke. Major bleeding and stroke/transient ischaemic attack events within 2 years (annual event rates, 290 patients/year) were less frequent than expected from CHADS2 (2.4% vs 9.6%), CHA2DS2-VASc (2.4% vs 8.3%) and HAS-BLED (3.1% vs 6.6%) risk scores (p<0.001, p=0.003, p=0.047, respectively). CONCLUSIONS: LAA closure with an occlusion device in patients contraindicated for oral anticoagulants is a therapeutic option associated with fewer thromboembolic and haemorrhagic events than expected from risk scores, particularly in the second year postimplantation