1,529 research outputs found
Agent-based simulation framework for airport collaborative decision making
Airport C
ollaborative Decision Making
(A
-
CDM)
is
based on information sharing.
A better use of resources can be
attained w
hen the different
stakeholders
at
airport operations
share their more accurate and updated information
.
One of the
main difficulties when dealing with this
information sharing
concept is the number of stakeholders involved and their
different
interest and
behaviour
:
aircraft operators
,
gro
und
handling companies,
airport authority,
air traffic control and the
Central Flow Management Unit
.
It is paramount to quantify the
benefit of an airport collaborative decision making strategy in
order to involve all these different organisations.
Simulat
ions are
required to analyse the
overall system and its
emerging
behaviour
.
This paper presents
the development and initial
t
est
ing of
a
n agent
-
based framework
,
which
allows
this
behavioural
analysis
to be done
.
The simulator explicitly
represents the diff
erent stakeholders
involved in the A
-
CDM and
the
interactions between them
during the 16 milestones defined
by
EUROCONTROL
o
n its A
-
CDM implementation manual
.
T
his framework allows independent
gradual
development of local
behaviours
and optimisation,
and
a gradual
increase
on
complexity and fidelity on the simulationsPeer ReviewedPostprint (published version
MLQ analysis of leadership in short sea shipping
Postprint (author’s final draft
La representación del éxodo rural en el cine español (1900-2020): evolución, causas y consecuencias territoriales
Rural depopulation has been a constant feature of contemporary Spanish history and has been amply studied from the perspective of geography. Recently, however, there has been considerable media attention given to the consequences of internal migration. Behind the alarming demographic statistics lies a nexus of processes which have been reflected in the cinema since its beginning. This paper explores these processes at work in the rural sending environment and receiving urban destination through an analysis of six representative Spanish films. The fictional representation through film of a complex reality provides insights into the internal and contextual keys to understanding the phenomenon of ‘empty Spain’ or ‘hollowed-out Spain’. The films illustrate the persistence of two conflicting ideas (the rural and urban), divergence about what constitutes development and the quality of life, and the processes leading to ‘demotanasia’.La despoblación rural ha sido una constante en la historia contemporánea de España, y ha sido ampliamente estudiada desde la perspectiva de la Geografía. Sin embargo, en los últimos tiempos se ha prestado una gran atención mediática a las consecuencias de las migraciones interiores. Detrás de las alarmantes estadísticas demográficas se esconde un nexo de procesos que se han reflejado en el cine desde sus inicios. Este trabajo explora estos procesos en funcionamiento en el entorno rural de envío y en el destino urbano de recepción a través del análisis de seis películas españolas representativas. La representación ficcional a través del cine de una realidad compleja permite conocer las claves internas y contextuales para entender el fenómeno de la “España vacía” o “España vaciada”. Las películas ilustran la persistencia de dos ideas contrapuestas (lo rural y lo urbano), la divergencia sobre lo que constituye el desarrollo y la calidad de vida, y los procesos que conducen a la “demotanasia”.Project of the State R&D&I Plan of the Ministry of Science and Innovation. Spanish cities in audiovisual fiction. Documentary record and territorial and audiovisual analysis (FACES-50). Reference: 2019/00436/001
El reconocimiento de los aprendizajes adquiridos por la experiencia previa: un nuevo reto para el sistema universitario
El propósito del Reconocimiento de los Aprendizajes derivados
de la Experiencia Previa (RAEP) es hacer visible el abanico de
competencias que posee una persona, independientemente del
contexto donde la adquisición de éstas tuvo lugar. En este
artículo se analiza el papel del reconocimiento del aprendizaje
experiencial dentro de una visión amplia de la educación y se
presentan sus elementos clave. Se comenta el rol del RAEP en la
educación superior, señalando asimismo las oportunidades y
desafíos que este tipo de procesos impone a los protagonistas de
la enseñanza universitaria
Effects of JPEG and JPEG2000 lossy compression on remote sensing image classification for mapping crops and forest areas
This study measures the effect of lossy image compression on the digital classification of crops and forest areas. A hybrid classification method using satellite images and other variables has been used. The results contribute interesting new data on the influence of compression on the quality of the produced cartography, both from a "by pixel" perspective and regarding the homogeneity of the obtained polygons. The classified area in classifications only carried out with radiometric variables or with NDVI and humidity (for crops) increases as image compression increases, although the increase is smaller for JPEG2000 formats and for crops. On the other hand, the classified area decreases in classifications which also take into account topoclimatic variables (for forests). Overall image accuracy diminishes at high compression ratios (CR), although the point of inflection occurs at different CR depending on the compression format. As a rule, the JPEG2000 format gives better results quantitatively for forests (accuracy and classified area) and visually (images with less "salt and pepper" effect) for both land covers
Acute toxicity of cerium oxide, titanium oxide and iron oxide nanoparticles using standardized tests
In this study, several standard toxicity tests have been performed on selected inorganic nanoparticles. Acute toxicity tests were selected according to their extensive use in toxicological studies and included phytotoxicity using several seeds, Daphnia magna and a bioluminescent test (Microtox®). All of them have been used in several international regulations as toxicity assays. In the case of nanoparticles (NPs), we have studied those of cerium oxide, titanium dioxide and iron oxide. Iron oxide NPs are well known and broadly used and were selected because of their low toxicity. Titanium dioxide and cerium oxide NPs are currently being used in several fields such as photocatalysis and medical applications, but their toxicity effects have been scarcely studied. Our results revealed that cerium NPs are extremely toxic in the entire set of tests conducted (inhibition higher than 80% at very low concentrations for the bioluminescence test and LC50 = 0.012 mg/ml of mortality in the assays of D. magna), whereas titanium NPs were practically inert in terms of toxicity (values similar to those of controls). The possible toxicological effect of the solvents necessary to stabilize NPs in liquid medium for the three cases (stabilizers) has been also studied. Only in the germination test (phytotoxicity) of some seeds they showed some detrimental effect to germination. In general, the standardized tests proposed in this study have proved to be very useful in the determination of NPs toxicity when no or few data are available, although further work is necessary in the case of the germination tes
5G-crosshaul: an SDN/NFV integrated fronthaul/backhaul transport network architecture
This article proposes an innovative architecture design for a 5G transport solution (dubbed 5G-Crosshaul) targeting the integration of existing and new fronthaul and backhaul technologies and interfaces. At the heart of the proposed design lie an SDN/NFV-based management and orchestration entity (XCI), and an Ethernet-based packet forwarding entity (XFE) supporting various fronthaul and backhaul traffic QoS profiles. The XCI lever-ages widespread architectural frameworks for NFV (ETSI NFV) and SDN (Open Daylight and ONOS). It opens the 5G transport network as a service for innovative network applications on top (e.g., multi-tenancy, resource management), provisioning the required network and IT resources in a flexible, cost-effective, and abstract manner. The proposed design supports the concept of network slicing pushed by the industry for realizing a truly flexible, sharable, and cost-effective future 5G system.This work has been funded by the EU H2020 project “5G- Crosshaul: The 5G Integrated Fronthaul/Backhaul” (Grant no. 671598)
Enzyme enhancement therapy through non-competitive pharmacological chaperones
Pharmacological chaperones, Chemical chaperones
,
Enzyme e
n-
hancement
therapy, GM1, Gangliosidosis, Morqui B, Lysosomal Storage Disease,
Lysosomal Storage DisordersMost Pharmacological chaperones (PC’s) described until now are
substrate analogues which bind to the active site of the target protein. C
ons
e-
quently, such PC’s also inhibit the target protein at higher concentrations thus
rendering a narrow therapeutic window and have poor drug-like properties.
Through our proprietary technology platform SEE-Tx™, we identify a new
generation of non-substrate competitive pharmacological chaperones which p
o-
tentially offer a much broader therapeutic window. What’s more, such co
m-
pounds are not substrate analogues, thus presenting much better drug-like pro
p-
erties, particularly for indications with CNS involvement. Here we present our
methodology to identify non-competitive pharmacological chaperones applied
to the enzyme beta-galactosidase, whose deficiency is related with GM1
Gangliosidosis and Morquio B.Postprint (published version
Origin and SEM analysis of aerosols in the high mountain of Tenerife (Canary Islands)
Focusing on aerosolized matter of relevance to respiratory health, a major public health issue worldwide, we studied mineral and biological aerosol (bioaerosol) composition (TSP and PM2.5) and geographical origins during dust intrusions in the Canary Islands. Seven days’ back- ward trajectories were assessed daily during March 2004 with the ends of back trajectories being the sampling station of Iza?a (high moun- tain, 2360 m a.s.l. at the Ca?adas del Teide National Park, Tenerife island), a free troposphere site allowing characterization of dust with low influence of other pollutant sources. Scanning electron microscopy (SEM) was used to survey major types of airborne particles in the dust plumes. Control, non-intrusion conditions correspond to Atlantic oceanic middle troposphere (OMT) air masses. Of the 14 samples taken, 1 corresponded to a control (clear atmosphere conditions), and the remaining 13 to dust intrusions, with the following sources: African Dust; EAM: mixture of Europe, Africa and Oceanic; MaA: maritime aerosols. Of the air masses, 79% were directly transported to the islands from Africa, and an increase of African dust events was detected when comparing with a 52-year previous data sequence. Quartz microcristals and aggregates of quartz and platy clay were the dominant minerals identified, with marine salt and gypsum also present. Freshwater diatom tests (from two Aulacoseira species) represented the most important biogenic aerosols, although fungi and pollen were also detected. The diverse and complex mixture of respirable particles in large quantities in airborne dust, especially from nearby Sahara and from the Sahelian region, is of maximum interest for air- way pathology in the Canaries, including the highly visited highlands in Tenerife.We acknowledge to the MEC (Ministry of Education and Science, Spain) and F.E.D.E.R. founds (E.U.) for the economical support of the following projects: CGL2005-03428-C04-02, CGL2007-66477-C02-02/CLI, CGL2008- 04740 and PI042005/033
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