Las matemáticas empresariales en el marco de cualificaciones del Espacio Europeo de Educación Superior (QF-EHEA)

Haremos comparaciones entre las metodologías docentes de las asignaturas de Matemáticas Empresariales impartidas en las principales universidades europeas, proponiendo medidas para la mejora de la calidad de estas asignaturas en nuestra universidad

Characterization of the antifungal activity of three rhizobacterial strains against Rhizoctonia solani

 In this study, three rhizobacterial strains were characterized by their ability to inhibit Rhizoctonia solani and tested in chili (Capsicum annuum L.) seedlings. Strains A46 and P61 were identified as Pseudomonas tolaasii, and S108 as Rhanella aquatilis. In the dual culture tests, all the strains inhibited the radial growth of R. solani. None of the three strains produced chitinases or volatile compounds, but they were found to produce siderophores. However, this last characteristic was not responsible for the rhizobacterial inhibitory effect on the growth of R. solani, other bacterial metabolites were possibly involved. The bacterial filtrates added to the potato dextrose agar medium (PDA) in a 3:7 ratio had significant antifungal activity, being the filtrate from strain S108 the one that showed the highest effect, with 56% fungal inhibition. The co-culture of strain A46 with the phytopathogenic fungi in potato dextrose broth (PDB) increased the antifungal activity of the rhizobacterial filtrate. The application of the rhizobacterial strains to Serrano chili decreased the R. solani-related mortality rate in seedlings; particularly, S108 had the greatest effect, which was similar to the fungicide effect. This study showed that the S108 strain has potential as a biofungicide to control R. solani in chili seedlings

Las Matemáticas Empresariales en el marco Erasmus Mundus

La creciente importancia de los métodos cuantitativos en las ciencias económicas y empresariales nos motiva a proponer una revisión detallada de los syllabus de las materias de matemáticas que se imparten en el Grado de Administración y Dirección de Empresas, con el objetivo de Investigar las correspondencias entre nuestros syllabus y los de las mas importantes universidades a nivel internacional (en el marco Erasmus Mundus). La investigación que proponemos llevará a cabo comparaciones exhaustivas de los temarios de esta categoría de asignaturas y sus metodologías docentes, y detectará las posibles discrepancias existentes en este tipo de estudios dependiendo de la universidad que los imparte. En una segunda fase, estudiaremos las causas de las posibles diferencias detectadas y, finalmente, produciremos un sistema capaz de sugerir medidas concretas que solventen los posibles problemas detectados

Prevalence and Associated Factors of Low Bone Mineral Density in the Femoral Neck and Total Hip in Axial Spondyloarthritis: Data from the CASTRO Cohort

Studies on osteoporosis in axial spondyloarthritis (axSpA) have focused on the lumbar segment, and few studies have assessed bone mineral density (BMD) in the hip and femoral neck in these patients. The aim of this study was to evaluate the prevalence of low BMD and osteopenia in the total hip or femoral neck and the factors associated with these conditions in axSpA patients. This was a single-centre, observational, cross-sectional study among consecutive patients with axSpA according to the ASAS criteria from the CASTRO registry. All patients underwent total hip and femoral neck DXA BMD measurements. Low BMD was defined as a Z-score less than −1, and osteopenia was defined as a T-score less than −1. Multivariate logistic and generalised linear regressions were used to evaluate factors independently associated with low BMD and osteopenia in the hip or femoral neck and those associated with variability in BMD, respectively. A total of 117 patients were included, among which 30.8% were female and the mean age was 45 years. A total of 36.0% of patients had low BMD (28.1% in the total hip and 27.4% in the femoral neck), and 56.0% of patients had osteopenia (44.7% in the total hip and 53.8% in the femoral neck). A multivariate logistic regression showed that age, radiographic sacroiliitis and ASAS-HI were independently associated with low BMD in the total hip or femoral neck. Factors that were independently associated with osteopenia were Body Mass Index, disease duration, radiographic sacroiliitis and ASAS-HI. In conclusion, 36% of the patients with axSpA had low BMD in the total hip or femoral neck. A younger age and radiographic sacroiliitis were the most important factors associated with decreased BMD

Análisis de los contenidos docentes de matemáticas en el doble grado ADE-Informática

Depto. de Economía Financiera y Actuarial y EstadísticaFac. de Ciencias Económicas y EmpresarialesFALSEsubmitte

Aprendizaje virtual de las matemáticas utilizando distintas TICs

Proyecto para ayudar al estudiantado en el aprendizaje de las Matemáticas y promover su aprendizaje autónomo. Todo ello, con materiales más visuales como vídeos, píldoras educativas, clases en modo síncrono, ejemplos con GeoGebra y cuestionarios

Evaluation of a real time pcr system for detection of Escherichia coli O157:H7 in ground beef

La infección por Escherichia coli O157:H7 es causa de diarrea con o sin sangre, colitis hemorrágica y síndrome urémico hemolítico (SUH) en humanos. El principal reservorio animal de E. coli O157:H7 son los bovinos y la carne bovina molida es una potencial fuente de infección. El objetivo de este trabajo fue evaluar un sistema comercial de PCR en tiempo real para la detección de E. coli O157:H7. Se determinó límite de detección, selectividad y robustez. Se contaminaron experimentalmente 50 muestras de carne molida bovina con 10 cepas de E. coli O157:H7 (10, 100 y 1000 UFC/25 g) y 20 cepas de bacterias no-E. coli O157:H7 (1000 UFC/25 g). El límite de detección dependió de la cepa analizada, el valor mínimo fue 6,1 UFC/25 g. La robustez fue óptima al modificar diferentes variables. Se obtuvo 100% de inclusividad y 100% de exclusividad. La técnica evaluada es una alternativa apropiada para la detección de E. coli O157:H7 a partir de carne bovina molida.Shiga toxin-producing Escherichia coli (STEC) cause non-bloody or bloody diar- rhea, hemorrhagic colitis and hemolytic uremic syndrome (HUS) in humans. Cattle are a major animal reservoir for E. coli O157:H7 and the ground beef are a potential source of infection. The aim of the present study was to evaluate a real time PCR commercial system for detection of E. coli O157:H7. Detection limit, selectivity and robustness were established. Fifty samples of ground beef were experimentally contaminated with 10 E. coli O157:H7 strains (10, 100 y 1000 CFU/25 g) and 20 non-E. coli O157:H7 strains (1000 CFU/25 g). The detection limit depended on the strain analyzed, the minimum values was 6,1 cfu/15 g. A good robustness was observed when different variables were introduced. Inclusivity and exclusivity were of 100%. The evaluated technique is an appropriate alternative for detection of E. coli O157:H7 from ground beef.Facultad de Ciencias Veterinaria

Evaluation of a real time pcr system for detection of Escherichia coli O157:H7 in ground beef

La infección por Escherichia coli O157:H7 es causa de diarrea con o sin sangre, colitis hemorrágica y síndrome urémico hemolítico (SUH) en humanos. El principal reservorio animal de E. coli O157:H7 son los bovinos y la carne bovina molida es una potencial fuente de infección. El objetivo de este trabajo fue evaluar un sistema comercial de PCR en tiempo real para la detección de E. coli O157:H7. Se determinó límite de detección, selectividad y robustez. Se contaminaron experimentalmente 50 muestras de carne molida bovina con 10 cepas de E. coli O157:H7 (10, 100 y 1000 UFC/25 g) y 20 cepas de bacterias no-E. coli O157:H7 (1000 UFC/25 g). El límite de detección dependió de la cepa analizada, el valor mínimo fue 6,1 UFC/25 g. La robustez fue óptima al modificar diferentes variables. Se obtuvo 100% de inclusividad y 100% de exclusividad. La técnica evaluada es una alternativa apropiada para la detección de E. coli O157:H7 a partir de carne bovina molida.Shiga toxin-producing Escherichia coli (STEC) cause non-bloody or bloody diar- rhea, hemorrhagic colitis and hemolytic uremic syndrome (HUS) in humans. Cattle are a major animal reservoir for E. coli O157:H7 and the ground beef are a potential source of infection. The aim of the present study was to evaluate a real time PCR commercial system for detection of E. coli O157:H7. Detection limit, selectivity and robustness were established. Fifty samples of ground beef were experimentally contaminated with 10 E. coli O157:H7 strains (10, 100 y 1000 CFU/25 g) and 20 non-E. coli O157:H7 strains (1000 CFU/25 g). The detection limit depended on the strain analyzed, the minimum values was 6,1 cfu/15 g. A good robustness was observed when different variables were introduced. Inclusivity and exclusivity were of 100%. The evaluated technique is an appropriate alternative for detection of E. coli O157:H7 from ground beef.Facultad de Ciencias Veterinaria

Emotional intelligence: A comparison between patients after first episode mania and those suffering from chronic bipolar disorder type i

Deficits in emotional intelligence (EI) were detected in patients with Bipolar Disorder (BD), but little is known about whether these deficits are already present in patients after presenting a first episode mania (FEM). We sought (i) to compare EI in patients after a FEM, chronic BD and healthy controls (HC); (ii) to examine the effect exerted on EI by socio-demographic, clinical and neurocognitive variables in FEM patients. Methods: The Emotional Intelligence Quotient (EIQ) was calculated with the MayerSalovey-Caruso Intelligence Test (MSCEIT). Performance on MSCEIT was compared among the three groups using generalized linear models. In patients after a FEM, the influence of socio-demographic, clinical and neurocognitive variables on the EIQ was examined using a linear regression model. Results: 184 subjects were included (FEM n=48, euthymic chronic BD type I n=75, HC n=61). BD patients performed significantly worse than HC on the EIQ (Mean Difference MD=10.09, Standard Error SE=3.14, p=0.004) and on the Understanding emotions branch (MD=7.46, SE=2.53, p=0.010). FEM patients did not differ from HC and BD on other measures of MSCEIT. In patients after a FEM, EIQ was positively associated with female sex (β=-0.293, p=0.034) and verbal memory performance (β=0.374, p=0.008). FEM patients performed worse than HC but better than BD on few neurocognitive domains. Conclusions: Patients after a FEM showed preserved EI, while patients in later stages of BD presented lower EIQ, suggesting that impairments in EI might result from the burden of disease and neurocognitive decline, associated with the chronicity of the illness

NRN1 Gene as a Potential Marker of Early-Onset Schizophrenia: Evidence from Genetic and Neuroimaging Approaches

Included in the neurotrophins family, the Neuritin 1 gene (NRN1) has emerged as an attractive candidate gene for schizophrenia (SZ) since it has been associated with the risk for the disorder and general cognitive performance. In this work, we aimed to further investigate the association of NRN1 with SZ by exploring its role on age at onset and its brain activity correlates. First, we developed two genetic association analyses using a family-based sample (80 early-onset (EO) trios (offspring onset ≤ 18 years) and 71 adult-onset (AO) trios) and an independent case control sample (120 healthy subjects (HS), 87 EO and 138 AO patients). Second, we explored the effect of NRN1 on brain activity during a working memory task (N-back task; 39 HS, 39 EO and 39 AO; matched by age, sex and estimated IQ). Different haplotypes encompassing the same three Single Nucleotide Polymorphisms(SNPs, rs3763180 rs10484320 rs4960155) were associated with EO in the two samples (GCT, TCC and GTT). Besides, the GTT haplotype was associated with worse N-back task performance in EO and was linked to an inefficient dorsolateral prefrontal cortex activity in subjects with EO compared to HS. Our results show convergent evidence on the NRN1 association with EO both from genetic and neuroimaging approaches, highlighting the role of neurotrophins in the pathophysiology of SZ