Identidades profesionales en educación desde una perspectiva de género

Este trabajo presenta los resultados de una investigación sobre los perfiles y trayectorias profesionales de pedagogos/as. Fundamentado en los planteamientos de la teoría feminista y en la línea de los estudios de género, el objetivo científico ha sido descubrir las formas cualitativamente distintas en que los profesionales experimentan, perciben y comprenden su realidad profesional. Conocer esta diversidad de caminos y perfiles que definen la identidad profesional de un/una pedagogo/a introduce datos novedosos para la construcción de una imagen ajustada a la actual práctica profesional de la pedagogía, así como para el análisis y reflexión sobre la heterogeneidad de modelos y trayectorias profesionales en educación, superando concepciones y modelos tradicionales, normativos y esterotipados respecto al ejercicio de una profesión.This paper presents the outcomes of an research focused on educators’ profiles and professional trajectories. Starting from feminist theory and gender studies, the main aim is to study the qualitatively different ways that professionals feel, perceive and understand their professional activity settings. To know this diversity of trajectories and profiles constituents of the educator’s professional identity introduce valuable data for the construction of a realistic picture of the current professional practise, as well as for the analysis and reflection on the heterogeneity of models and professional routes in education. This involves breaking traditional, standard and stereotyped models of the professional practise

Effect of the Vitrification of Human Oocytes on the Binding Capacity and Acrosome Status of Human Sperm

Conocer los aspectos moleculares que acontecen en el proceso de unión de los espermatozoides humanos a la zona pelúcida (ZP) humana es uno de los grandes retos de la biología de la Reproducción. Por otra parte conocer si el proceso de fecundación puede verse afectado por la criopreservación de los gametos femeninos sigue siendo otra cuestión debatida en la literatura. En base a esto, el objetivo principal de este trabajo fue conocer si la vitrificación ovocitaria puede alterar la interacción de los espermatozoides con el glicocáliz de la ZP y demostrar si la ZP de estos ovocitos pierde la capacidad de inducir la reacción acrosómica en los espermatozoides. Según nuestros resultados el método de vitrificación ovocitaria cerrado (S3) no altera la capacidad de unión de los espermatozoides a la zona pelúcida, ni la capacidad de ésta para inducir la reacción acrosómica.To know the molecular aspects that occur in the process of human sperm binding to the human zona pellucida (ZP) is one of the great challenges of reproduction biology. Moreover knowing if the fertilization process may be affected by cryopreservation of female gametes is still another issue discussed in the literature. Based on this, the main objective of this study was to determine whether the oocyte vitrification may alter the interaction of sperm with the glycocalyx of ZP and show whether these oocytes lost the ability to induce the acrosome reaction in sperm. According to our results the oocyte closed vitrification method (S3) does not alter the ability of the sperm binding to the zona pellucida, and their ability to induce the acrosome reaction.Este trabajo fue subvencionado por el Vicerrectorado de Investigación de la Universidad de Alicante (VIGROB-137)

Eficiencia en el sector del transporte por carretera, Clústeres y Plataformas Logísticas

El objetivo del presente trabajo es estudiar la eficiencia del sector industrial de transporte por carretera en España, prestando especial atención a Aragón. Para ello, hemos estimado una frontera de producción estocástica Translog con información extraída de la base de datos SABI. Esto nos ha permitido i) trazar un mapa geográfico de la eficiencia por Comunidades Autónomas, y ii) estudiar la influencia de los clúster y de las plataformas logística en la eficiencia de las empresas. Nuestros resultados indican que la eficiencia de sector es alta, siendo Castilla y León, País Vasco y Asturias, las comunidades más eficientes. Además, los datos sugieren que tanto aquellas empresas localizadas en provincias con plataformas logísticas, como las que pertenecen a un clúster, tienden a ser más eficientes.<br /

Synergistic interaction in the analgesic-like effects of maqui berry and citrus Is antagonized by sweeteners

Although physiologically pain has a protective function, in many diseases, it is one of the most prominent symptoms. Today, new trends are focused on finding more natural alternatives to conventional treatments to alleviate it. Thereby, the purpose of this investigation was to obtain preclinical data of the antinociceptive properties of a lyophilized obtained from a newly designed maqui–citrus beverage alone and added with different sweeteners. To achieve this objective, maqui berry and citrus pharmacological activity were studied separately, as well as the interaction of both ingredients. In addition, due to the controversy generated regarding the intake of sugars, related to different metabolic diseases, the influence of different sweeteners (stevia, sucralose, or sucrose) was studied to determine their possible influence on the bioactive compounds of this product. For the attainment of our goals, a pharmacological evaluation, using the 1% formalin test, a nociceptive pain model in mice, was performed by using a sub-efficacious dosage of Maqui (25 mg/kg, i.p.) alone and combined with citrus, and then compared with the effects obtained in the presence of the different sweeteners. As a result, the antinociceptive response of the maqui was synergized in the presence of citrus in the neurogenic and inflammatory phases of the formalin test. However, this response was partially or totally reduced in the presence of the sweeteners. Our study gives preclinical evidence that a combination of maqui and citrus might exert beneficial actions to relieve pain, whereas the presence of sweeteners could reduce or avoid it.This work was partially supported by Consejo Nacional de Ciencia y Tecnología (CONACYT) grant numbers 226454 and 256448 and Institutional projects numbers INP-NC123280.0 and INP-NC17073.0. Also, was partially funded by the Spanish MINECO through Research Project AGL2016-75332-C2-1-R (AEI/FEDER, UE), the Spanish MICIN through Research Project PID2019- 104212RD-100, and VA by a FPI grant (BES-2017-079754

Anticonvulsant and Antioxidant Effects of Tilia americana

Tilia genus is commonly used around the world for its central nervous system properties; it is prepared as tea and used as tranquilizing, anticonvulsant, and analgesic. In this study, anticonvulsant activity of the Tilia americana var. mexicana inflorescences and leaves was investigated by evaluating organic and aqueous extracts (100, 300, and 600 mg/kg, i.p.) and some flavonoids in the pentylenetetrazole-induced seizures in mice. Moreover, antioxidant effect of these extracts and flavonoids was examined in an in vitro study by using spectrophotometric technique. Significant activity was observed in the methanol extract from inflorescences. An HPLC analysis of the methanol extract from inflorescences and leaves of Tilia allowed demonstrating the respective presence of some partial responsible flavonoid constituents: quercetin (20.09 ± 1.20 μg/mg and 3.39 ± 0.10 μg/mg), rutin (3.52 ± 0.21 μg/mg and 8.94 ± 0.45 μg/mg), and isoquercitrin (1.74 ± 0.01 μg/mg and 1.24 ± 0.13 μg/mg). In addition, significant but different antioxidant properties were obtained among the flavonoids and the extracts investigated. Our results provide evidence of the anticonvulsant activity of Tilia reinforcing its utility for central nervous system diseases whose mechanism of action might involve partial antioxidant effects due to the presence of flavonoids

Antinociceptive effects of maqui-berry (Aristotelia chilensis (Mol.) Stuntz)

Maqui-berry is characterised by presenting a high concentration of (poly)phenols, accounting anthocyanins (cyanidin and delphinidin) for over 85% of the total. These coloured flavonoids have demonstrated potential neurological activity, but the evidence of their antinociceptive properties is scarce. In order to cover this gap, different doses (suitable for human administration) of a maqui-berry powder (1.6% anthocyanin), using enteral and parenteral routes of administration, were compared at central and peripheral levels using a nociceptive pain model (formalin test) in mice. Gastric damage analysis as possible adverse effects of analgesic and anti-inflammatory drugs was also explored. Dose-antinociceptive response was confirmed using both routes of administration and in both neurogenic and inflammatory phases of the formalin test, without gastric damage. In conclusion, these preliminary data provide evidence of pharmacological properties of maqui-berry to alleviate nociceptive pain.This work was partially supported by Consejo Nacional de Ciencia y Tecnología (CONACYT) grant numbers 226454 and 256448 and Institutional projects numbers INP-NC123280.0 and INP-NC17073.0. Also, was partially funded by the Spanish MINECO through Research Project AGL2016-75332-C2-1-R (AEI/FEDER, UE), the Spanish MICIN through Research Project PID2019-104212RD-100, and VA by a FPI [grant number BES-2017-079754]

Description of a new species of Perichaena (Myxomycetes) from arid areas of Argentina

8 pages, 23 figures.[EN] A new species of the myxomycete genus Perichaena is described in this paper. The new species, named Perichaena calongei, was found during intensive studies of arid areas of the Monte desert in Argentina. It has been found directly in the field from the provinces of Catamarca, La Rioja, Salta and San Juan, in the Northwest of Argentina, and isolated from moist chamber cultures of native plant species collected in Catamarca, Jujuy, Salta and San Juan. The characters that make this species unique in the genus are the combination of the morphology of the sporocarps, the structure and dehiscence of the peridium, and the ornamentation of the capillitium. The morphology of the my xo - mycete specimens was examined using light microscopy with Nomarski interference contrast, and scanning electron microscopy. Micrographs of relevant morphological characters are included. A key to facilitate the identification of the stipitate species of Perichaena is also proposed.[ES] Se describe una nueva especie, Perichaena calongei, que fue encontrada en el desierto de Monte, en las zonas áridas del nor - oeste de Argentina. Los cuerpos fructíferos se encontraron fructificados en el campo, también se obtuvieron por cultivo en cámara húmeda de plantas recolectadas en las provincias de Catamarca, Jujuy, La Rioja, Salta y San Juan. La combinación de caracteres de la morfología del esporocarpo, de la estructura y tipo de dehiscencia del peridio, y de la ornamentación del capilicio, distinguen esta especie del resto de las conocidas en el género. La morfología de la especie se analizó con un microscopio óptico dotado de contraste interferencial de Nomarski y con un microscopio electrónico de barrido, se incluyen ilustraciones de las estructuras observadas. Se propone una clave dicotómica para la identificación, a nivel mundial, de las especies estipitadas del género Perichaena.This research has been supported by the Ministry of Science and Innovation of Spain (grant CGL2005-00320/BOS and CGL2008-00720/BOS).Peer reviewe

Use of the stock market simulator in the Faculty of Administrative and Social Sciences of the UV as a tool to support the learning of students

El objetivo de este artículo es exponer la manera en que se ha implementado la simulación en los estudiantes que cursan la experiencia educativa Finanzas Internacionales de la carrera de Administración de Negocios Internacionales, así como los beneficios que ha aportado en su formación. Por lo que en primera instancia, se presenta una revisión de literatura sobre el uso de los simuladores educativos a través del tiempo, posteriormente se aborda la metodología empleada en el curso iniciando como base del conocimiento la parte teórica, para luego aplicarlos en el uso del simulador bursátil donde éste favorece significativamente en el aprendizaje, pues los acerca al mundo real de una manera fácil, en seguida se muestran los resultados obtenidos los cuales revelan que los simuladores son una herramienta única para crear un entorno de enseñanza-aprendizaje efectivo, ya que proporcionan una visión integral de los saberes teóricos y prácticos, finalizando con las conclusiones.The objective of this article is to expose the way in which simulation has been implemented in students who are studying the International Finance educational experience of the International Business Administration career, as well as the benefits it has provided in their training. Therefore, in the first instance, a review of the literature on the use of educational simulators over time is presented, later the methodology used in the course is addressed, starting as a basis of knowledge the theoretical part, and then applying them in the use of the Stock market simulator where it significantly favors learning, as it brings them closer to the real world in an easy way, then the results obtained are shown which reveal that simulators are a unique tool to create an effective teaching-learning environment, since provides a comprehensive view of the theoretical and practical knowledge ending with the conclusions

Integrative analysis of DNA copy number, DNA methylation and gene expression in multiple myeloma reveals alterations related to relapse

Multiple myeloma (MM) remains incurable despite the introduction of novel agents, and a relapsing course is observed in most patients. Although the development of genomic technologies has greatly improved our understanding of MM pathogenesis, the mechanisms underlying relapse have been less thoroughly investigated. In this study, an integrative analysis of DNA copy number, DNA methylation and gene expression was conducted in matched diagnosis and relapse samples from MM patients. Overall, the acquisition of abnormalities at relapse was much more frequent than the loss of lesions present at diagnosis, and DNA losses were significantly more frequent in relapse than in diagnosis samples. Interestingly, copy number abnormalities involving more than 100 Mb of DNA at relapse significantly affect the gene expression of these samples, provoking a particular deregulation of the IL-8 pathway. On the other hand, no significant modifications of gene expression were observed in those samples with less than 100 Mb affected by chromosomal changes. Although several statistical approaches were used to identify genes whose abnormal expression at relapse was regulated by methylation, only two genes that were significantly deregulated in relapse samples (SORL1 and GLT1D1) showed a negative correlation between methylation and expression. Further analysis revealed that DNA methylation was involved in regulating SORL1 expression in MM. Finally, relevant changes in gene expression observed in relapse samples, such us downregulation of CD27 and P2RY8, were most likely not preceded by alterations in the corresponding DNA. Taken together, these results suggest that the genomic heterogeneity described at diagnosis remains at relapse.This work was partially supported by the Instituto de Salud Carlos III-Cofinanciación con fondos FEDER (PI080568, PS0901897 and PI13/00111), the Gerencia Regional de Salud, Junta de Castilla y León (GRS202/A08 and GRS 702/A/11), the Spanish Myeloma Network Program (RD06/0020/0006) and the Asociación Española Contra el Cáncer (AECC, GCB120981SAN).Peer Reviewe