Improving the Wear and Corrosion Resistance of Maraging Part Obtained by Cold Gas Spray Additive Manufacturing

The use of the cold gas spray (CGS) process as a metal additive manufacturing (MAM) technique for metallic part production has been deeply studied recently, mainly due to its advantages over other MAM techniques. CGS MAM is a high-productivity technique with a very low level of particle oxidation, microstructural changes, phase transformations, or deleterious residual thermal stresses in the part. The use of CGS MAM to produce maraging parts represents a gain for the industry by saving machining time and preventing raw material waste. Its wear resistance and corrosion behavior were evaluated in this work and were compared with cermet coatings deposited by high-velocity oxy-fuel (HVOF) on the CGS MAM maraging. This work presents the innovative and effective combination of different thermal spraying processes and materials to obtain MAM maraging parts with higher wear resistance, evaluating abrasion, sliding, and water erosion wear type

The influence of the powder characteristics on 316L stainless steel coatings sprayed by cold gas spray

Thermally sprayed 316L stainless steel coatings are commonly used on metallic structures due to their corrosion and wear resistance when compared to carbon steel. Cold Gas Spray (CGS) is a convenient thermal spray process to deposit 316L coatings, producing thick and very dense coatings, with almost no deleterious changes on the feedstock properties to the coating condition. The powder characteristics have influence on the microstructure of the coating, such as porosity and oxide contents, which alter its corrosion and wear behavior. CGS is an efficient technique to reduce the problems associated with material melting commonly found in other conventional thermal spray methods. In this work, different 316L powders, produced by different manufacturers, were deposited by CGS, applying the same equipment and parameters, with the objective to evaluate the relation between the powders' characteristics and coating properties. Their microstructure, adherence, hardness, as well as the performance on corrosion and wear testing were evaluated. The water atomized powders presented in general better results than gas atomized powders

Assessment of attribute-based credentials for privacy-preserving road traffic services in smart cities

Smart cities involve the provision of advanced services for road traffic users. Vehicular ad hoc networks (VANETs) are a promising communication technology in this regard. Preservation of privacy is crucial in these services to foster their acceptance. Previous approaches have mainly focused on PKI-based or ID-based cryptography. However, these works have not fully addressed the minimum information disclosure principle. Thus, questions such as how to prove that a driver is a neighbour of a given zone, without actually disclosing his identity or real address, remain unaddressed. A set of techniques, referred to as Attribute-Based Credentials (ABCs), have been proposed to address this need in traditional computation scenarios. In this paper, we explore the use of ABCs in the vehicular context. For this purpose, we focus on a set of use cases from European Telecommunications Standards Institute (ETSI) Basic Set of Applications, specially appropriate for the early development of smart cities. We assess which ABC techniques are suitable for this scenario, focusing on three representative ones—Idemix, U-Prove and VANET-updated Persiano systems. Our experimental results show that they are feasible in VANETs considering state-of-the-art technologies, and that Idemix is the most promising technique for most of the considered use cases.This work was supported by the MINECO grant TIN2013-46469-R (SPINY: Security and Privacy in the Internet of You); the CAM grant S2013/ICE-3095 (CIBERDINE: Cybersecurity, Data, and Risks) and by the MINECO grant TIN2016-79095-C2-2-R (SMOG-DEV - Security mechanisms for fog computing: advanced security for devices). Jose Maria de Fuentes and Lorena Gonzalez were also supported by the Programa de Ayudas para la Movilidad of Carlos III University of Madrid

Protective Effect of Melatonin Against Mitomycin C-Induced Genotoxic Damage in Peripheral Blood of Rats

Mitomycin C (MMC) generates free radicals when metabolized. We investigated the effect of melatonin against MMC-induced genotoxicity in polychromatic erythrocytes and MMC-induced lipid peroxidation in brain and liver homogenates. Rats (N = 36) were classified into 4 groups: control, melatonin, MMC, and MMC + melatonin. Melatonin and MMC doses of 10 mg/kg and 2 mg/kg, respectively, were injected intraperitoneally. Peripheral blood samples were collected at 0, 24, 48, 72, and 96 hours posttreatment and homogenates were obtained at 96 hours posttreatment. The number of micronucleated polychromatic erythrocytes (MN-PCE) per 1000 PCE was used as a genotoxic marker. Malondialdehyde (MDA) plus 4-hydroxyalkenal (4-HDA) levels were used as an index of lipid peroxidation. The MMC group showed a significant increase in MN-PCE at 24, 48, 72, and 96 hours that was significantly reduced with melatonin begin coadministrated. No significant differences were found in lipid peroxidation. Our results indicate that MMC-induced genotoxicity can be reduced by melatonin

Psychophysiological response of military pilots in different combat flight maneuvers in a flight simulator

Objective: To analyze the psychophysiological response during takeoff, landing, air-air attack and air-ground attack maneuvers. Methods: A total of 11 expert pilots (age=33.36 (5.37)) from the Spanish Air Force participated in this cross-sectional study. Participants had to complete in a flight simulator the following missions: 1) takeoff; 2) Air-air attack; 3) Air-Ground attack, and 4) Landing. The electroencephalographic activity (EEG) and heart rate variability (HRV) were collected during all these maneuvers. Results: Significant higher values of theta (during takeoff, air-air attack and air-ground attack) EEG power spectrum were obtained when compared to baseline. Significant difference in the P3 scalp location was observed between landing and takeoff maneuvers in the beta EEG power spectrum. Furthermore, significant lower values of HRV were obtained during takeoff, landing, air-air attack and air-ground attack when compared to baseline values. Also, landing showed a higher sympathetic response when compared to takeoff maneuver. Conclusion: Takeoff, landing, air-air attack or air-ground attack maneuvers performed in a flight simulator produced significant changes in the electroencephalographic activity and autonomic modulation of professional pilots. Beta EEG power spectrum modifications suggest that landing maneuvers induced more attentional resources than takeoff. In the same line, a reduced HRV during landing was obtained when compared to takeoff. These results should be considered to training purposes

Structure and function of the alfa-rhizobia non-coding transcriptome investigated by RNAseq

Conferencia presentada en: I Spanish-Portuguese Congress on Beneficial Plant-Microbe Interactions (BeMiPlant) and XVIII National Meeting of the Spanish Society of Nitrogen Fixation (XVIII SEFIN). Oeiras, Portugal, 17-19 octubre (2022)This work was supported by grants BFU2017-82645-P and PID2020-114782GB-I00 funded by MCIN/AEI/10.13039/501100011033 and by “ERDF A way of making Europe” (BFU2017-82645-P), and grant P20_00185 funded by Junta de Andalucía PAIDI/FEDER/EU, awarded to J.I.J.-Z., and by grant US-1250546 funded by FEDER/Universidad de Sevilla to J.M.V

Improvement of learning through European educational projects

Proceedings TEEM 2020: Eighth International Conference on Technological Ecosystems for Enhancing Multiculturality.[EN]The purpose of this article is to set out the research plan for the doctoral thesis, which deals with the definition of a methodological guide for the successful use of digital technologies in education, especially in eLearning, taking as a reference European educational projects that have been successful in achieving an improvement in the teaching and learning process. We live in an increasingly digital society that requires citizens to be prepared to adapt to the needs of the moment and to solve the problems that arise. For this to be possible, the education system must be prepared to adequately train future citizens who will join a changing labor market. To this end, teachers must be trained and know how to carry out efficient educational projects that allow them to make the most of the potential of ICT in the classroom or in distance education. The situation experienced during the 2019-2020 school year with the COVID-19 pandemic has tested the education system and its ability to adapt to a situation where the use of distance education was required and where ICT was very much needed in most of the cases to bring education to the homes. These factors make it very necessary to work for a better teaching professionalization. Therefore, the main objective of this PhD work is to enable teachers to design their projects, involving electronic learning, in a more effective way. To achieve this, what better than to use the educational projects compiled in the Erasmus+ results platform, which allow the analysis of project typology, outcomes, topics and to see those that have been catalogued as a good practice or success story. This database will be a key tool to gather information together with the collaboration of the main actors of those projects that have been successful. A methodological guide would allow teachers and teacher trainers to know the key factors that help to achieve a good design of educational projects and allow an optimal use of ICT resources and the greatest impact on the teaching-learning process

Resistin Regulates Pituitary Lipid Metabolism and Inflammation In Vivo and In Vitro

The adipokine resistin is an insulin-antagonizing factor that also plays a regulatory role in inflammation, immunity, food intake, and gonadal function and also regulates growth hormone (GH) secretion in rat adenopituitary cells cultures with the adipokine. Although adipose tissue is the primary source of resistin, it is also expressed in other tissues, including the pituitary. The aim of this study is to investigate the possible action of resistin on the lipid metabolism in the pituitary gland in vivo (rats in two different nutritional status, fed and fast, treated with resistin on acute and a chronic way) and in vitro (adenopituitary cell cultures treated with the adipokine). Here, by a combination of in vivo and in vitro experimental models, we demonstrated that central acute and chronic administration of resistin enhance mRNA levels of the lipid metabolic enzymes which participated on lipolysis and moreover inhibiting mRNA levels of the lipid metabolic enzymes involved in lipogenesis. Taken together, our results demonstrate for the first time that resistin has a regulatory role on lipid metabolism in the pituitary gland providing a novel insight in relation to the mechanism by which this adipokine can participate in the integrated control of lipid metabolism.Sara Borrell Postdoctoral program; BFU 2011 and CIBER Obesidad y Nutricion (Instituto de Salud Carlos Tercero (ISCIII), Ministerio de Ciencia e Innovacion). Juan de la Cierva Program (Ministerio de Educacion y Ciencia)S

Cross-country migration linked to people who inject drugs challenges the long-term impact of national HCV elimination programmes

To the Editor: As of 2018, the majority of Western European countries – including Spain – have lifted restrictions to therapy based on disease severity in the context of HCV infections.1 Long overdue, most national elimination programmes now also include access to care for people who inject drugs (PWID), 2 who are at the core of ongoing HCV transmission.3 Macías et al.4 have recently shown in this Journal that high viral cure rates can be achieved in this group, hereby providing evidence that targeting PWID in treatment programmes is worthwhile. However, the extent to which such national efforts can reduce the HCV burden not only depends on the uptake into care and treatment success rates, it is also determined by the relative importance of within-country transmission and virus importation from elsewhere. As the chronic nature of most HCV infections hampers reliably reconstructing contact networks from patient interviews, virus genetic data can be a valuable alternative source of information for elucidating the geographic history of virus lineages (e.g. [5], [6]). Using such data, we have recently shown that for the most prevalent subtype among PWID in Spain (40%, 7), HCV1a, infections often link to infections abroad – in recent years >50% link to Western European countries, mostly European Union (EU) member states – as opposed to other infections ..