The perception and attitudes of pharmacists and their users towards vaccination and vaccinehesitancy. A cross sectional study

Background and objectives: The increase in vaccine hesitancy threatens advances in public health and causes vaccine-preventable diseases outbreaks in infra-vaccinated communities. This study aims to determine and compare the perception and attitudes towards vaccination among pharmacy users, pharmacy students and community pharmacists. Methods: A cross-sectional observational study was conducted during March and April 2020, surveying perceptions and attitudes towards vaccination in Barcelona (Spain). Statistical analysis was assessed by chi2 test and multivariate regression. Statistical significance when P < .05. The association measure of Odds Ratio and its 95% confidence interval (CI) were estimated. Results: A high percentage of hesitant opinions (44%) among pharmacy users was observed, despite high vaccine coverage (80%). Some showed mistrust in the health system (23.3%) and a statistically significant association was found between previous negative experiences with vaccination and hesitant attitudes (OR: 3.04; 95%CI 1.16 to 7.93; P = .02). Of all surveyed pharmacy users, those over 44 years old showed a stronger hesitant attitude towards vaccines (OR: 2.63; 95%CI 1.11 to 6.19; P = .03), and 40% undervalued influenza vaccine, including risk groups. Both pharmacy students and community pharmacists had a positive attitude towards vaccination. While only 16% of surveyed pharmacists vaccinated against influenza during the 2019/2020 influenza seasonal campaign, most of them considered their vaccination important to the profession (61%). Conclusions: Active promotion and education of the population and reliable communication on vaccines are some of the needs that community pharmacists can solve, claiming their role as highly qualified health professionals in daily contact with the population

Transformation Optics Approach to Plasmon-Exciton Strong Coupling in Nanocavities

We investigate the conditions yielding plasmon-exciton strong coupling at the single emitter level in the gap between two metal nanoparticles. A quasi-analytical transformation optics approach is developed that makes possible a thorough exploration of this hybrid system incorporating the full richness of its plasmonic spectrum. This allows us to reveal that by placing the emitter away from the cavity center, its coupling to multipolar dark modes of both even and odd parity increases remarkably. This way, reversible dynamics in the population of the quantum emitter takes place in feasible implementations of this archetypal nanocavity.Comment: 5 pages, 4 figure

A comparison of BPMN 2.0 with other notations for manufacturing processes

In order to study their current practices and improve on them, manufacturing firms need to view their processes from several viewpoints at various abstraction levels. Several notations have been developed for this purpose, such as Value Stream Mappings or IDEF models. More recently, the BPMN 2.0 standard from the Object Management Group has been proposed for modeling business processes. A process organizes several activities (manual or automatic) into a single higher-level entity, which can be reused elsewhere in the organization. Its potential for standardizing business interactions is well-known, but there is little work on using BPMN 2.0 to model manufacturing processes. In this work some of the previous notations are outlined and BPMN 2.0 is positioned among them after discussing it in more depth. Some guidelines on using BPMN 2.0 for manufacturing are offered, and its advantages and disadvantages in comparison with the other notations are presented

Surface and core detonations in rotating white dwarfs

The feasibility of the double detonation mechanism—surface helium detonation followed by complete carbon detonation of the core—in a rotating white dwarf with mass ;1Me is studied using three-dimensional hydrodynamic simulations. A rapid rigid rotation of the white dwarf was assumed, so that its initial spherical geometry is considerably distorted. Unlike spherically symmetric models, we found that when helium ignition is located far from the spinning axis, the detonation fronts converge asynchronically at the antipodes of the ignition point. Nevertheless, the detonation of the carbon core still remains as the most probable outcome. The detonation of the core gives rise to a strong explosion, matching many of the basic observational constraints of Type Ia supernovae (SNe Ia). We conclude that the double detonation mechanism also works when the white dwarf is rapidly rotating. These results provide further evidence for the viability of sub-Chandrasekhar-mass models as well as some double degenerate models (those having some helium fuel at the merging moment), making them appealing channels for the production of SN Ia events.Peer ReviewedPostprint (published version

Microbiota composition of the dorsal patch of reproductive male Leptonycteris yerbabuenae.

Bacteria and other types of microbes interact with their hosts in several ways, including metabolic pathways, development, and complex behavioral processes such as mate recognition. During the mating season, adult males of the lesser long-nosed agave pollinator bat Leptonycteris yerbabuenae (Phyllostomidae: Glossophaginae) develop a structure called the dorsal patch, which is located in the interscapular region and may play a role in kin recognition and mate selection. Using high-throughput sequencing of the V4 region of the 16S rRNA gene, we identified a total of 2,847 microbial phylotypes in the dorsal patches of eleven specimens. Twenty-six phylotypes were shared among all the patches, accounting for 30 to 75% of their relative abundance. These shared bacteria are distributed among 13 families, 10 orders, 6 classes and 3 phyla. Two of these common bacterial components of the dorsal patch are Lactococcus and Streptococcus. Some of them-Helcococcus, Aggregatibacter, Enterococcus, and Corynebacteriaceae-include bacteria with pathogenic potential. Half of the shared phylotypes belong to Gallicola, Anaerococcus, Peptoniphilus, Proteus, Staphylococcus, Clostridium, and Peptostreptococcus and specialize in fatty acid production through fermentative processes. This work lays the basis for future symbiotic microbe studies focused on communication and reproduction strategies in wildlife

Macroscopic QED for quantum nanophotonics: Emitter-centered modes as a minimal basis for multiemitter problems

We present an overview of the framework of macroscopic quantum electrodynamics from a quantum nanophotonics perspective. Particularly, we focus our attention on three aspects of the theory that are crucial for the description of quantum optical phenomena in nanophotonic structures. First, we review the light-matter interaction Hamiltonian itself, with special emphasis on its gauge independence and the minimal and multipolar coupling schemes. Second, we discuss the treatment of the external pumping of quantum optical systems by classical electromagnetic fields. Third, we introduce an exact, complete, and minimal basis for the field quantization in multiemitter configurations, which is based on the so-called emitter-centered modes. Finally, we illustrate this quantization approach in a particular hybrid metallodielectric geometry: two quantum emitters placed in the vicinity of a dimer of Ag nanospheres embedded in a SiN microdiskThis work has been funded by the European Research Council (doi: 10.13039/501100000781) through grant ERC-2016-StG-714870 and by the Spanish Ministry for Science, Innovation, and Universities – Agencia Estatal de Investigación (doi: 10.13039/ 501100011033) through grants RTI2018-099737-B-I00, PCI2018-093145 (through the QuantERA program of the European Commission), and MDM-2014-0377 (through the María de Maeztu program for Units of Excellence in R&D