35 research outputs found

    Cantera honda de Posadas (Cordova): An extraction of stone material presumably linked to the olive exploitation of the middle course of the Guadalquivir in Roman Age

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    URL del artículo en la web de la Revista: https://www.upo.es/revistas/index.php/romula/article/view/3207La Cantera Honda de Posadas constituye una extracción intensiva de piedra al aire libre, en foso o pozo, con una única estrategia extractiva destinada a la consecución de piezas cilíndricas con unas medidas prácticamente homogéneas. Se trata de una cantera de piedra gonfolita en la que se practica una extracción cilíndrica y vertical, que genera frentes de forma tubular, y que presenta un volumen de explotación de en torno a 13.500 m3. Esta cantera ha sido, hasta el momento, apenas referida en la bibliografía precedente, sin que se hubiera realizado un estudio monográfico intensivo de la misma. En este trabajo planteamos un estudio preliminar de este espectacular enclave productivo, proponiendo como hipótesis su posible vinculación con la elaboración de molinos oleícolas destinados a abastecer las numerosas almazaras del curso medio del Guadalquivir en época romana.La Cantera Honda de Posadas is an intensive quarry of stone in the open air, in pit or well, with an only extractive strategy aimed at achieving cylindrical pieces with practically homogeneous measurements. It is a gonfolita stone quarry in which a cylindrical and vertical extraction is carried out. The quarry generates tubular extraction fronts and has a volume of exploitation of 13.500 m3. This location has been hardly mentioned in the previous bibliography so far and lacks an intensive monographic study about it. In this work we propose a preliminary study of this spectacular enclave of extraction, suggesting as hypothesis its possible link with the elaboration of olive presses destined to supply the numerous mills of the middle course of the Guadalquivir in Roman times.Universidad Pablo de Olavid

    Cantera Honda de Posadas (Córdoba): una extracción de material lapídeo presumiblemente vinculada a la explotación olivarera del curso medio del Guadalquivir en época romana

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    La Cantera Honda de Posadas constituye una extracción intensiva de piedra al aire libre, en foso o pozo, con una única estrategia extractiva destinada a la consecución de piezas cilíndricas con unas medidas prácticamente homogéneas. Se trata de una cantera de piedra gonfolita en la que se practica una extracción cilíndrica y vertical, que genera frentes de forma tubular, y que presenta un volumen de explotación de en torno a 13.500 m3. Esta cantera ha sido, hasta el momento, apenas referida en la bibliografía precedente, sin que se hubiera realizado un estudio monográfico intensivo de la misma. En este trabajo planteamos un estudio preliminar de este espectacular enclave productivo, proponiendo como hipótesis su posible vinculación con la elaboración de molinos oleícolas destinados a abastecer las numerosas almazaras del curso medio del Guadalquivir en época romana.----------------------------------------------------------------------------La Cantera Honda de Posadas is an intensive quarry of stone in the open air, in pit or well, with an only extractive strategy aimed at achieving cylindrical pieces with practically homogeneous measurements. It is a gonfolita stone quarry in which a cylindrical and vertical extraction is carried out. The quarry generates tubular extraction fronts and has a volume of exploitation of 13.500 m3. This location has been hardly mentioned in the previous bibliography so far and lacks an intensive monographic study about it. In this work we propose a preliminary study of this spectacular enclave of extraction, suggesting as hypothesis its possible link with the elaboration of olive presses destined to supply the numerous mills of the middle course of the Guadalquivir in Roman times

    Mecanismo de fuerza constante

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    Número de publicación: ES2683962 A1 (28.09.2018) También publicado como: ES2683962 B2 (21.02.2019) Número de Solicitud: Consulta de Expedientes OEPM (C.E.O.) P201700551 (28.03.2017)Mecanismo de fuerza constante del tipo de los utilizados para mantener un nivel de fuerza constante sobre el eslabón de entrada. El mecanismo incorpora una guía curva (1), cuya cara exterior define dos pistas de rodadura laterales (3a, 3b) sobre las que ruedan sendas ruedas (5a, 5b). Ambas ruedas (5a, 5b) están montadas sobre un mismo eje (6), sobre el que actúa un resorte de extensión (8). El otro extremo de este resorte se articula a un eje fijo (7). Por acción de una cadena de rodillos (10) las ruedas (5a, 5b) se desplazan sobre sendas pistas de rodadura laterales (3a, 3b) mientras que el resorte de extensión (8) se opone al movimiento. La geometría de la curva definida por las pistas de rodadura laterales (3a, 3b) es tal que la fuerza aplicada sobre la cadena de rodillos (10) se mantiene constante para cualquier posición de las ruedas (5a, 5b).Universidad de Almería y Universidad de Sevill

    Reduction of ureteral stent encrustation by modulating the urine pH and inhibiting the crystal film with a new oral composition: a multicenter, placebo controlled, double blind, randomized clinical trial

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    Background: Encrustation of ureteral double J stents is a common complication that may affect its removal. The aim of the proposed study is to evaluate the efficacy and safety of a new oral composition to prevent double J stent encrustation in indwelling times up to 8 weeks. Methods: A double-blinded, multicenter, placebo-controlled trial was conducted with 105 patients with indwelling double J stents enrolled across 9 public hospitals in Spain. The patients were randomly assigned (1:1) into intervention (53 patients) or placebo (52 patients) groups for 3 to 8 weeks and both groups self-monitored daily their morning urine pH levels. The primary outcome of analysis was the degree of stent ends encrustation, defined by a 4-point score (0 - none; 3 - global encrustation) using macroscopic and electron microscopy analysis of crystals, after 3 to 8-w indwelling period. Score was exponentially transformed according to calcium levels. Secondary endpoints included urine pH decrease, stent removal, and incidence of adverse events. Results: The intervention group benefits from a lower global encrustation rate of stent ends than placebo group (1% vs 8.2%; p < 0.018). Mean encrustation score was 85.12 (274.5) in the placebo group and 18.91 (102.27) in the intervention group (p < 0.025). Considering the secondary end points, treated patients reported greater urine pH decreases (p = 0.002). No differences in the incidence of adverse events were identified between the groups. Conclusions: Our data suggest that the use of this new oral composition is beneficial in the context of ureteral double J indwelling by decreasing mean, as well as global encrustation

    Health‑related quality of life in patients newly diagnosed with prostate cancer: CAPLIFE study

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    Funding Funding for open access charge: Universidad de Granada / CBUA. This research was funded by Regional Ministry of Health and Families of Andalusia/Consejería de Salud y Familias de la Junta de Andalucía (PI-0514-2016).Purpose To analyse the Health-Related Quality of Life (HRQoL) at diagnosis of patients with prostate cancer (PCa) according to tumour extension and urinary symptomatology and to explore factors associated with HRQoL. Methods 408 Controls and 463 PCa cases were included. Eligibility criteria were a new diagnosis of PCa (cases), 40–80 years of age, and residence in the participating hospitals’ coverage area for ≥ 6 months before recruitment. HRQoL was evaluated using the 12-Item Short-Form Health Survey, Mental (MCS) and Physical Component Summaries (PCS), and urinary symptoms with the International Prostate Symptom Score. HRQoL scores for all PCa cases, according to tumour extension and urinary symptoms, were compared with controls. In addition, information about lifestyles and comorbidities was collected and its association with low HRQoL (lower scores) were explored using logistic regression models. Results Overall cases had similar PCS score, but lower MCS score than controls. The lowest standardised scores for both PCS and MCS were reached by cases with severe urinary symptoms and a metastatic tumour [mean (SD); PCS: 41.9 (11.5), MCS: 42.3 (10.3)]. Having “below” PCS and MCS scores was associated with the presence of three or more comorbidities in the cases [aOR = 2.86 (1.19–6.84) for PCS and aOR = 3.58 (1.37–9.31) for MCS] and with severe urinary symptomatology [aOR = 4.71 (1.84–12.08) for PCS and aOR = 7.63 (2.70–21.58) for MCS]. Conclusion The mental dimension of HRQoL at diagnosis of patients with PCa was lower than in controls, especially for cases with severe urinary symptoms and a metastatic tumour. Comorbidities and urinary symptoms were variables associated with the HRQoL of PCa cases.Funding for open access charge: Universidad de Granada/CBUARegional Ministry of Health and Families of Andalusia/Consejería de Salud y Familias de la Junta de Andalucía (PI-0514-2016

    Cantera Honda de Posadas (Córdoba): una extracción de material lapídeo presumiblemente vinculada a la explotación olivarera del curso medio del Guadalquivir en época romana

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    La Cantera Honda de Posadas constituye una extracción intensiva de piedra al aire libre, en foso o pozo, con una única estrategia extractiva destinada a la consecución de piezas cilíndricas con unas medidas prácticamente homogéneas. Se trata de una cantera de piedra gonfolita en la que se practica una extracción cilíndrica y vertical, que genera frentes de forma tubular, y que presenta un volumen de explotación de en torno a 13.500 m3. Esta cantera ha sido, hasta el momento, apenas referida en la bibliografía precedente, sin que se hubiera realizado un estudio monográfico intensivo de la misma. En este trabajo planteamos un estudio preliminar de este espectacular enclave productivo, proponiendo como hipótesis su posible vinculación con la elaboración de molinos oleícolas destinados a abastecer las numerosas almazaras del curso medio del Guadalquivir en época romana.La Cantera Honda de Posadas is an intensive quarry of stone in the open air, in pit or well, with an only extractive strategy aimed at achieving cylindrical pieces with practically homogeneous measurements. It is a gonfolita stone quarry in which a cylindrical and vertical extraction is carried out. The quarry generates tubular extraction fronts and has a volume of exploitation of 13.500 m3. This location has been hardly mentioned in the previous bibliography so far and lacks an intensive monographic study about it. In this work we propose a preliminary study of this spectacular enclave of extraction, suggesting as hypothesis its possible link with the elaboration of olive presses destined to supply the numerous mills of the middle course of the Guadalquivir in Roman times

    Thermoplastic starch/polyvinyl alcohol blends modification by citric acid–glycerol polyesters

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    Thermoplastic starch/polyvinyl alcohol (TPS/PVA) films have limitations for being used in long–term applications due to starch retrogradation. This leads to plasticizer migration, especially when low molecular weight plasticizers such as glycerol, are used. In this work, we employed mixtures of oligomers based on glycerol citrates with higher molecular weight than glycerol as plasticizers for potato–based TPS/PVA blends obtained by melt–mixing. This constitutes an alternative to reduce plasticizer migration while keeping high swelling degree, and to provide high mechanical performance. The novelty lies in the usage of these oligomers by melt-mixing technique, aspect not deeply explored previously and that represents the first step towards industrial scalability. Prior to the blending process, oligomers mixtures were prepared with different molar ratios of citric acid (0–40 mol%) and added them. This minimizes the undesirable hydrolysis effect of free carboxylic groups on starch chains. The results demonstrated that the migration of plasticizers in TPS/PVA blends decreased by up to 70 % when the citric acid content increased. This reduction was attributed to the higher molecular weight (the majority in the range 764–2060 Da) and the 3D structure of the oligomers compared to using raw glycerol. Furthermore, the films exhibited a 150 % increase in Young's modulus and tensile strength without a reduction in elongation at break, while maintaining a high gel content, due to a moderate crosslinking.This work was partially supported by the Spanish Ministry of Science and Ministry of Economy, Industry and Competitiveness and the Spanish MINECO (PID2019-108632RB-100 and PID2021-126445OB-I00, respectively) and Generalitat Valenciana (PROMETEO CIPROM/2021/027). This work was also partially supported by the TED2021-130389B-C21 research project, funded by MCIN/AEI/10.13039/501100011033 and by the European Union NextGenerationEU/PRTR. Juana M. Pérez acknowledges support from University of Almería (HIPATIA2021_04 fellowship)

    Reduction of ureteral stent encrustation by modulating the urine pH and inhibiting the crystal film with a new oral composition: a multicenter, placebo controlled, double blind, randomized clinical trial.

    No full text
    Encrustation of ureteral double J stents is a common complication that may affect its removal. The aim of the proposed study is to evaluate the efficacy and safety of a new oral composition to prevent double J stent encrustation in indwelling times up to 8 weeks. A double-blinded, multicenter, placebo-controlled trial was conducted with 105 patients with indwelling double J stents enrolled across 9 public hospitals in Spain. The patients were randomly assigned (1:1) into intervention (53 patients) or placebo (52 patients) groups for 3 to 8 weeks and both groups self-monitored daily their morning urine pH levels. The primary outcome of analysis was the degree of stent ends encrustation, defined by a 4-point score (0 - none; 3 - global encrustation) using macroscopic and electron microscopy analysis of crystals, after 3 to 8-w indwelling period. Score was exponentially transformed according to calcium levels. Secondary endpoints included urine pH decrease, stent removal, and incidence of adverse events. The intervention group benefits from a lower global encrustation rate of stent ends than placebo group (1% vs 8.2%; p  Our data suggest that the use of this new oral composition is beneficial in the context of ureteral double J indwelling by decreasing mean, as well as global encrustation. This trial was registered at www.clinicaltrials.gov under the name "Combined Use of a Medical Device and a Dietary Complement in Patient Urinary pH Control in Patients With an Implanted Double J Stent" with date 2nd November 2017, code NCT03343275, and URL
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