10 research outputs found
Ligand-free palladium catalysed Heck reaction of methyl 2-acetamido acrylate and aryl bromides as key step in the synthesis of enantiopure substituted phenylalanines
Full text linkChemInform Abstract: Asymmetric Synthesis of Functionalized 1,2,3,4-Tetrahydroquinolines.
No full textEster- and ketone-substituted (±)-1-alkyl-6-nitro-1,2,3,4-tetrahydroquinolines by a tandem SNAr-Michael reaction
No full textRemote Control of the C-3-C-4 Double-Bond Epoxidation of a Chiral 1,2-Dihydroquinoline: Application to the Synthesis of (-)-(R)-Sumanirole (PNU-95666E)
No full textInternational audienceA twelve-step synthesis of (-)-(R)-sumanirole starting from quinoline is described. The first synthetic approach, using a chiral Reissert adduct, was too problematic to be pursued further. In the second successful approach, the authors took advantage of the stereoselective epoxidation of a 1,2-dihydroquinoline bearing an Evans' chiral auxiliary at N-1
Remote Control of the C-3-C-4 Double-Bond Epoxidation of a Chiral 1,2-Dihydroquinoline: Application to the Synthesis of (-)-(R)-Sumanirole (PNU-95666E)
No full textβ-Hydroxy-tetrahydroquinolines from Quinolines Using Chloroborane: Synthesis of the Peptidomimetic FISLE-412
No full textSynthesis and spectral properties of Methyl-Phenyl pyrazoloquinoxaline fluorescence emitters: Experiment and DFT/TDDFT calculations
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