Quasi-Dynamic Analysis of a Local Distribution System with Distributed Generation. Study Case: The IEEE 13 Node System

La generación distribuida es una de las estrategias más aceptadas para atender el aumento de la demanda de electricidad a nivel mundial. Desde el año 2014 las entidades gubernamentales en Colombia han emitido leyes y resoluciones para promover y regular la entrada en operación de diferentes tecnologías de generación, en el sistema eléctrico del país. Incorporar sistemas de generación distribuida en redes de distribución convencionales puede traer consigo problemas si previamente no se realizan los estudios que permitan determinar las consecuencias de la entrada en operación de estas nuevas tecnologías de generación. Este panorama representa un nuevo desafío para los operadores de las redes de distribución, ya que deben garantizar que los sistemas que administran puedan integrar estas nuevas fuentes de generación, sin afectar el correcto funcionamiento de la red eléctrica. En este artículo se modifica el sistema IEEE de 13 nodos incorporando las curvas de carga de los tres tipos de consumidores del sector eléctrico colombiano en las cargas del modelo y se integran sistemas de generación distribuida a partir de fuentes no convencionales de energía a dos nodos del sistema, con el objetivo de hacer un análisis cuasi-dinámico de las diferentes variables eléctricas que permitan determinar qué impacto tienen estas nuevas tecnologías en un sistema de distribución local. Como resultado, los perfiles de voltaje y potencia activa/reactiva no muestran cambios considerables en el comportamiento de la red eléctrica, pero sí se observa que, en los escenarios de simulación donde opera la generación distribuida, el sistema tiende a un aumento considerable en las corrientes y pérdidas presentes en las líneas. Así, se concluye que existen dos alternativas para no tener inconvenientes con la operación de los nuevos nodos con generación distribuida: operar de manera aislada esa parte del sistema o reforzar la red de distribución local a través de la implementación de nuevas líneas de distribución en el sistema.Distributed generation is one of the most accepted strategies to attend the increase in electrical demand around the world. Since 2014, Colombian government agencies have enacted laws and resolutions to promote and regulate the introduction of different generation technologies into the country’s electrical system. The incorporation of distributed generation systems into conventional distribution networks can cause problems if technical studies are not previously carried out to determine the consequences of the start of the operations of these new generation technologies. This scenario represents a new challenge for distribution networks operators because they must ensure that their systems can integrate these new generation sources without affecting the correct operation of the grid. In this article, the IEEE 13 nodes system is modified by incorporating the load curves of the three types of consumers in the Colombian electricity market into the model. Additionally, distributed generation systems from non-conventional sources of energy are integrated into two system nodes in order to perform a quasi-dynamic analysis of the different electrical variables, which can be used to determine the impact of these new technologies on a local distribution system. The voltage profiles and active and reactive power do not show considerable changes in the behavior of the electrical network; however, in the simulation scenarios where distributed generators are operating, the system exhibits a considerable increase in lines losses. There are two alternatives to manage these unusual levels in the operation of the nodes with distributed generation: (1) operating these new DG nodes in islanded mode or (2) strengthening the local distribution system through the implementation of new distribution lines in the network

Total femoral replacement: a challenging but promising limb salvage option

Total femur replacement is a limb salvage surgery indicated for patients with oncological and non-oncological pathologies of the femur. Given the characteristics of the patients, there are essential perioperative considerations such as the previous treatment with chemotherapy or radiotherapy, prevention of thromboembolic events, hemorrhage management, and booking of an intensive care unit. As demanding as the surgical technique is, preventing extensive fibrosis, major bleeding, acetabular defects, and changes in normal anatomy is possible. The complications described include infection, structural failure, tumor progression, aseptic loosening, and soft tissue failure. Functional results and survival vary from series to series, but reports exist as high as 70% at ten years

Quasi-dynamic analysis of the inclusion of generation distributed in power systems, study case: IEEE 30 nodes system

The latest advances in Distributed Generation (GD) systems have opened a new stage in planning strategies for electrical systems. It is of great importance to determine the economic and technical impact of the installation and commissioning of GD in those parts of the power system where they were previously installed. In this research, the process of optimization of the economic dispatch allows to find the optimum power values to which all the units of the 30-node IEEE system, modified with GD nodes, must be dispatched, trying to minimize generation costs in conventional units. The results of this optimization process are implemented in a "Quasi-Dynamic Simulation" that allows to identify and analyze the parameters that vary in the system over time, in addition to dimensioning the values of power losses in the lines and transformers of the system. Los últimos avances en los sistemas de generación distribuida (GD) han abierto un nuevo escenario en las estrategias de planeación de los sistemas eléctricos. Toma gran importancia determinar los impactos económico y técnico que acarrean la instalación y la puesta en operación de GD en aquellos lugares del sistema de potencia donde antes solo estaban instaladas. En esta investigación, un proceso de optimización del despacho económico permite encontrar los valores óptimos de potencia a los que deben despachar todas las unidades del sistema IEEE de 30 nodos, modificado con nodos de GD, y procurar que se minimicen los costos de generación en las unidades convencionales. Los resultados de este proceso de optimización se implementan en unas ‘simulaciones cuasidinámicas’ que permiten identificar y analizar los parámetros que varían en el sistema a lo largo del tiempo, además de dimensionar los valores de pérdidas de potencia en las líneas y en los transformadores del sistema

Oligonucleotide-capped nanoporous anodic alumina biosensor as diagnostic tool for rapid and accurate detection of Candida auris in clinical samples

[EN] Candida auris has arisen as an important multidrug-resistant fungus because of several nosocomial outbreaks and elevated rates of mortality. Accurate and rapid diagnosis of C. auris is highly desired; nevertheless, current methods often present severe limitations and produce misidentification. Herein a sensitive, selective, and time-competitive biosensor based on oligonucleotide-gated nanomaterials for effective detection of C. auris is presented. In the proposed design, a nanoporous anodic alumina scaffold is filled with the fluorescent indicator rhodamine B and the pores blocked with different oligonucleotides capable of specifically recognize C. auris genomic DNA. Gate opening modulation and cargo delivery is controlled by successful DNA recognition. C. auris is detected at a concentration as low as 6 CFU/mL allowing obtaining a diagnostic result in clinical samples in one hour with no prior DNA extraction or amplification steps.The authors want to thank the Spanish Government (project RTI2018-100910-B-C41 (MCIU/AEI/FEDER, UE)), the Generalitat Valenciana (project PROMETEO/2018/024), Universitat Politecnica de Valencia-Instituto de Investigacion Sanitaria La Fe (AURISGATE project) and Centro de Investigacion Biomedica en Red en Bioingenieria, Biomateriales y Nanomedicina (NANOPATH AND CANDI-EYE projects) for support. L.P thanks MINECO for his predoctoral fellowship. S.S. thanks the Instituto de Salud Carlos III and the European Social Fund for the financial support "Sara Borrell" (CD16/000237).Pla, L.; Santiago-Felipe, S.; Tormo-Mas, MÁ.; Ruiz-Gaitán, A.; Peman, J.; Valentín, E.; Sancenón Galarza, F.... (2021). Oligonucleotide-capped nanoporous anodic alumina biosensor as diagnostic tool for rapid and accurate detection of Candida auris in clinical samples. Emerging microbes & infections. 10(1):407-415. https://doi.org/10.1080/22221751.2020.187041140741510

Educación y desarrollo personal

Esta obra, fruto de investigaciones teóricas y prácticas, señala los caminos privilegiados que conducen a la persona hacia la plenitud humana y la felicidad. El primero de ellos, la familia, escenario educativo por excelencia, puesto que en su seno se establecen los vínculos constitutivos de la personalidad: paternidad, maternidad y filiación; la familia es el lugar donde cada ser humano es reconocido y amado por sí mismo y aprende el buen ejercicio de su libertad. La escuela y la universidad constituyen el segundo espacio formativo de singular importancia; en este se ayuda a los jóvenes a desarrollar armónicamente la inteligencia, la voluntad y los afectos; lo anterior, a través de la educación formal –científica y humanística– y de aquellas actividades –como el voluntariado o el servicio social– que permiten la expresión de la compasión, la solidaridad, las cualidades artísticas, etc. Distintos ámbitos de desarrollo personal que apuntan a la consolidación de líderes virtuosos capaces de construir una cultura de la vida que camine hacia la paz.Prólogo. 1 · La familia, escuela de libertad para el desarrollo integral. 2 · Formación de la voluntad en jóvenes universitarios: realidad y claves educativas. 3 · Liderazgo virtuoso: un camino de plenitud personal. 4 · Experiencias de voluntariado como estrategia para fomentar habilidades emocionales en jóvenes universitarios. 5 · El amor como factor de desarrollo humano en la pareja. 6 · Hacia una cultura de paz desde el desarrollo humano y la universidad. 7 · El pathos cristiano, vía que conduce a una educación en la compasión. 8 · Estrategias de búsqueda, clasificación y verificación de la información en la web. 9 · Trabajo social y educación para el servicio. 10 · Formación del artista en la obra El arte como experiencia de John Dewey.1a

CHARACTERIZING THE V -BAND LIGHT-CURVES OF HYDROGEN-RICH TYPE II SUPERNOVAE

We present an analysis of the diversity of V-band light-curves of hydrogen-rich type II supernovae. Analyzing a sample of 116 supernovae, several magnitude measurements are defined, together with decline rates at different epochs, and time durations of different phases. It is found that magnitudes measured at maximum light correlate more strongly with decline rates than those measured at other epochs: brighter supernovae at maximum generally have faster declining light-curves at all epochs. We find a relation between the decline rate during the 'plateau' phase and peak magnitudes, which has a dispersion of 0.56 magnitudes, offering the prospect of using type II supernovae as purely photometric distance indicators. Our analysis suggests that the type II population spans a continuum from low-luminosity events which have flat light-curves during the 'plateau' stage, through to the brightest events which decline much faster. A large range in optically thick phase durations is observed, implying a range in progenitor envelope masses at the epoch of explosion. During the radioactive tails, we find many supernovae with faster declining light-curves than expected from full trapping of radioactive emission, implying low mass ejecta. It is suggested that the main driver of light-curve diversity is the extent of hydrogen envelopes retained before explosion. Finally, a new classification scheme is introduced where hydrogen-rich events are typed as simply 'SNII' with an s2 value giving the decline rate during the 'plateau' phase, indicating its morphological type.Comment: Accepted for publication in ApJ. Revised edition corrects errors in affiliation number

Clinical practice guideline for surgical antimicrobial prophylaxis

La infección del sitio quirúrgico (ISQ) es una de las principales causas de infecciones asociadas a la atención en salud (IAAS), con un impacto significativo en la mortalidad y morbilidad del paciente quirúrgico, así como en los costos asociados a la atención en salud. El adecuado uso de la profilaxis quirúrgica antimicrobiana es un aspecto fundamental en la reducción del riesgo de ISQ, dado que su utilización inapropiada o indiscriminada puede representar un riesgo para los pacientes y contribuir al desarrollo de resistencia a los antimicrobianos, por lo que resulta de importancia generar directrices que permitan orientar el uso adecuado de antimicrobianos en la profilaxis del paciente quirúrgico, con el objetivo de obtener mejores desenlaces clínicos y propender por un uso racional de antibióticos. La presente guía contiene recomendaciones para profilaxis antibiótica de pacientes sometidos a procedimiento quirúrgico, basadas en la evidencia, realizadas mediante el proceso de adaptación de guías de práctica clínica para el contexto colombiano.Q4Pacientes sometidos a Profilaxis quirúrgica antimicrobianaSurgical site infection (SSI) is one of the main causes of healthcare associated infections (HAI), with a significant impact on the mortality and morbidity of the surgi-cal patient, as well as on the costs associated with health care. The adequate use of surgical antimicrobial prophylaxis being a fundamental aspect in reducing the risk of SSI, taking into account that the inappropriate or indiscriminate use of antibiotics in surgical prophylaxis may represent a risk for patients and contribute to the development of antimicrobial resistance, so it is important to generate guidelines that guide the appropriate antimicrobial prophylaxis in the surgical patient, with the aim of obtaining better clinical outcomes and promoting a rational use of antibiotics. This guide contains recommendations for antibiotic prophylaxis in patients undergoing a surgical procedure, based on evidence, carried out through the process of adapting clinical practice guidelines for the Colombian context.https://orcid.org/0000-0002-5392-7083https://orcid.org/0000-0003-2568-4667Revista Nacional - IndexadaCN

Latin American study of hereditary breast and ovarian cancer LACAM : a genomic epidemiology approach

Q2Q1Artículo original1-13Purpose: Hereditary Breast and Ovarian Cancer (HBOC) syndrome is responsible for ~5–10% of all diagnosed breast and ovarian cancers. Breast cancer is the most common malignancy and the leading cause of cancer-related mortality among women in Latin America (LA). The main objective of this study was to develop a comprehensive understanding of the genomic epidemiology of HBOC throughout the establishment of The Latin American consortium for HBOC-LACAM, consisting of specialists from 5 countries in LA and the description of the genomic results from the first phase of the study. Methods: We have recruited 403 individuals that fulfilled the criteria for HBOC from 11 health institutions of Argentina, Colombia, Guatemala, Mexico and Peru. A pilot cohort of 222 individuals was analyzed by NGS gene panels. One hundred forty-three genes were selected on the basis of their putative role in susceptibility to different hereditary cancers. Libraries were sequenced in MiSeq (Illumina, Inc.) and PGM (Ion Torrent-Thermo Fisher Scientific) platforms. Results: The overall prevalence of pathogenic variants was 17% (38/222); the distribution spanned 14 genes and varied by country. The highest relative prevalence of pathogenic variants was found in patients from Argentina (25%, 14/57), followed by Mexico (18%, 12/68), Guatemala (16%, 3/19), and Colombia (13%, 10/78). Pathogenic variants were found in BRCA1 (20%) and BRCA2 (29%) genes. Pathogenic variants were found in other 12 genes, including high and moderate risk genes such as MSH2, MSH6, MUTYH, and PALB2. Additional pathogenic variants were found in HBOC unrelated genes such as DCLRE1C, WRN, PDE11A, and PDGFB. Conclusion: In this first phase of the project, we recruited 403 individuals and evaluated the germline genetic alterations in an initial cohort of 222 patients among 4 countries. Our data show for the first time in LA the distribution of pathogenic variants in a broad set of cancer susceptibility genes in HBOC. Even though we used extended gene panels, there was still a high proportion of patients without any detectable pathogenic variant, which emphasizes the larger, unexplored genetic nature of the disease in these populations

Resultados Semilleros de Investigación 2009-2010

La publicación recoge los doce informes finales de investigación presentados por los estudiantes de ocho Semilleros 1 y cuatro Semilleros 2, correspondientes a la convocatoria 2009–2010 y se constituye en el Número 25 de la Serie de Investigaciones en Construcción, si bien este es el primer Número publicado en formato digital que UNIJUS se permite poner a disposición no sólo de la comunidad universitaria, sino también de la sociedad colombiana e internacional, interesada en los temas estudiados por los jóvenes investigadores de la Facultad de Derecho, Ciencias Políticas y Sociales de la Universidad Nacional de Colombia

Como funciona el protocolo OAI-PMH en la recuperación de información

In this article it is tried to describe the operation of protocol OAI - PMH (Open Archives Initiative - Protocol Metadata Harvesting), from the interoperability between the supplier of data and the supplier of services by means of the example of a information necessity of a user of a Centre Specialized in Lawyer, is there where it started this request of information to a supplier of services that used the protocol to communicate with a supplier of data, which will resort to repository to look for the information required by the initial user