603 research outputs found
Color television system using single gun color cathode ray tube
Two-primary color and single gun system provides quality differential color and variation in brightness for specific colors by varying current and controlling duty cycle of electron beam. Number of video amplifiers, deflection circuits, and guns required to display color TV picture is reduced and less complex tube is required
Editor\u27s Notes
Previewing contents of the Asian Law Symposium
Editor\u27s Notes
Previewing contents of the Asian Law Symposium
Aggregation of soil and climate input data can underestimate simulated biomass loss and nitrate leaching under climate change
Predicting areas of severe biomass loss and increased N leaching risk under climate change is critical for applying appropriate adaptation measures to support more sustainable agricultural systems. The frequency of annual severe biomass loss for winter wheat and its coincidence with an increase in N leaching in a temperate region in Germany was estimated including the error from using soil and climate input data at coarser spatial scales, using the soil-crop model CoupModel. We ran the model for a reference period (1980-2010) and used climate data predicted by four climate model(s) for the Representative Concentration Pathways (RCP) 2.6, 4.5 and 8.5. The annual median biomass estimations showed that for the period 2070-2100, under the RCP8.5 scenario, the entire region would suffer from severe biomass loss almost every year. Annual incidence of severe biomass loss and increased N leaching was predicted to increase from RCP4.5 to the 8.5 scenario. During 2070-2100 for RCP8.5, in more than half of the years an area of 95% of the region was projected to suffer from both severe biomass loss and increased N leaching. The SPEI3 predicted a range of 32 (P3 RCP4.5) to 55% (P3 RCP8.5) of the severe biomass loss episodes simulated in the climate change scenarios. The simulations predicted more severe biomass losses than by the SPEI index which indicates that soil water deficits are important in determining crop losses in future climate scenarios. There was a risk of overestimating the area where "no severe biomass loss + increased N leaching" occurred when using coarser aggregated input data. In contrast, underestimation of situations where "severe biomass loss + increased N leaching" occurred when using coarser aggregated input data. Larger annual differences in biomass estimations compared to the finest resolution of input data occurred when aggregating climate input data rather than soil data. The differences were even larger when aggregating both soil and climate input data. In half of the region, biomass could be erroneously estimated in a single year by more than 40% if using soil and climate coarser input data. The results suggest that a higher spatial resolution of especially climate input data would be needed to predict reliably annual estimates of severe biomass loss and N leaching under climate change scenarios
Aggregation of soil and climate input data can underestimate simulated biomass loss and nitrate leaching under climate change
Predicting areas of severe biomass loss and increased N leaching risk under climate change is critical for applying appropriate adaptation measures to support more sustainable agricultural systems. The frequency of annual severe biomass loss for winter wheat and its coincidence with an increase in N leaching in a temperate region in Germany was estimated including the error from using soil and climate input data at coarser spatial scales, using the soil-crop model CoupModel. We ran the model for a reference period (1980–2010) and used climate data predicted by four climate model(s) for the Representative Concentration Pathways (RCP) 2.6, 4.5 and 8.5. The annual median biomass estimations showed that for the period 2070–2100, under the RCP8.5 scenario, the entire region would suffer from severe biomass loss almost every year. Annual incidence of severe biomass loss and increased N leaching was predicted to increase from RCP4.5 to the 8.5 scenario. During 2070–2100 for RCP8.5, in more than half of the years an area of 95% of the region was projected to suffer from both severe biomass loss and increased N leaching. The SPEI3 predicted a range of 32 (P3 RCP4.5) to 55% (P3 RCP8.5) of the severe biomass loss episodes simulated in the climate change scenarios. The simulations predicted more severe biomass losses than by the SPEI index which indicates that soil water deficits are important in determining crop losses in future climate scenarios. There was a risk of overestimating the area where “no severe biomass loss + increased N leaching” occurred when using coarser aggregated input data. In contrast, underestimation of situations where “severe biomass loss + increased N leaching” occurred when using coarser aggregated input data. Larger annual differences in biomass estimations compared to the finest resolution of input data occurred when aggregating climate input data rather than soil data. The differences were even larger when aggregating both soil and climate input data. In half of the region, biomass could be erroneously estimated in a single year by more than 40% if using soil and climate coarser input data. The results suggest that a higher spatial resolution of especially climate input data would be needed to predict reliably annual estimates of severe biomass loss and N leaching under climate change scenarios.Peer reviewe
Неинвазивные методы изучения коллекторских свойств ископаемых углей
Розглянуті фізичні неінвазивні методи дослідження, які дозволяють отримати уявлення про такі властивості вугільної речовини як повна пористість, питома поверхня, розподіл пір по розмірах та ін., що дають уявлення про колекторні властивості вугільних пластів. Отримані характеристики структури порового простору, що визначають транспортні властивості флюїдів.Physical noninvasion methods of studies are considered, which allow characterizing such
properties of coal as total porosity, specific surface, size distribution of pores and etc.,
demonstrating the reservoir features of coal beds. The description of pore space structure,
determining transport properties of fluids, is presented
Periphyton responses to eutrophication in the Florida Everglades: Cross-system patterns of structural and compositional change
We examined periphyton along transects in five Everglades marshes and related compositional and functional aspects to phosphorus(P ) gradients caused by enriched inflows. Results were compared to those of a P-addition experiment in a pristine Everglades marsh. While the water total P (TP) concentration was not related to P load in the marshes or experiment the concentration of TP in periphyton was strongly correlated with the distance from the P source. Increased P concentration in periphyton was associated with a loss of biomass,p articularly of the calcifying mat-forming matrix, regardless of the growth form of the periphyton (epiphytic, floating,or epilithic). Diatom species composition was also strongly related to P availability, but the TP optima of many species varied among marshes. Enriched periphyton communities were found 14 km downstream of P inputs to one marsh that has been receiving enhanced P loads for decades, where other studies using different biotic indicators show negligible change in the same marsh. Although recovery trajectories are unknown, periphyton indicators should serve as excellent metrics for the progression or amelioration of P-related effects in the Everglades
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Predicting survival from colorectal cancer histology slides using deep learning: A retrospective multicenter study
BACKGROUND: For virtually every patient with colorectal cancer (CRC), hematoxylin-eosin (HE)-stained tissue slides are available. These images contain quantitative information, which is not routinely used to objectively extract prognostic biomarkers. In the present study, we investigated whether deep convolutional neural networks (CNNs) can extract prognosticators directly from these widely available images.
METHODS AND FINDINGS: We hand-delineated single-tissue regions in 86 CRC tissue slides, yielding more than 100,000 HE image patches, and used these to train a CNN by transfer learning, reaching a nine-class accuracy of >94% in an independent data set of 7,180 images from 25 CRC patients. With this tool, we performed automated tissue decomposition of representative multitissue HE images from 862 HE slides in 500 stage I-IV CRC patients in the The Cancer Genome Atlas (TCGA) cohort, a large international multicenter collection of CRC tissue. Based on the output neuron activations in the CNN, we calculated a "deep stroma score," which was an independent prognostic factor for overall survival (OS) in a multivariable Cox proportional hazard model (hazard ratio [HR] with 95% confidence interval [CI]: 1.99 [1.27-3.12], p = 0.0028), while in the same cohort, manual quantification of stromal areas and a gene expression signature of cancer-associated fibroblasts (CAFs) were only prognostic in specific tumor stages. We validated these findings in an independent cohort of 409 stage I-IV CRC patients from the "Darmkrebs: Chancen der Verhütung durch Screening" (DACHS) study who were recruited between 2003 and 2007 in multiple institutions in Germany. Again, the score was an independent prognostic factor for OS (HR 1.63 [1.14-2.33], p = 0.008), CRC-specific OS (HR 2.29 [1.5-3.48], p = 0.0004), and relapse-free survival (RFS; HR 1.92 [1.34-2.76], p = 0.0004). A prospective validation is required before this biomarker can be implemented in clinical workflows.
CONCLUSIONS: In our retrospective study, we show that a CNN can assess the human tumor microenvironment and predict prognosis directly from histopathological images
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