The variance of B. Pincibono

Even the best oscillators exhibit random fluctuations of their instantaneous frequency . A usual measurement method is the Alla n variance which relies on the difference between two successive instantaneous frequency samples . For frequency fluctuations wit h power spectrum of the kind of 1/f or 1/f2 this variance is well suited . However for a faster increase near the zero frequency, it is divergent . With the variance of Picinbono, the idea is to use a second order difference, based on three measurements . Thi s yields a spectral shaping which can cancel a power spectrum divergence of the kind 1/f3 or 1/f4 . Hence a very accurate tool to analyse the various noise sources of an oscillator . We have compared these two variances, plus a third one that is intended t o remove a frequency drift, in the case of a highly stable quartz oscillator at 10 MHz . The variance of B . Picinbono turns out to b e indeed more efficient to reduce very low components of the frequency noise, as well as certain types of nonstationarities (drift an d random walk) .Même le meilleur oscillateur présente du bruit de phase et de fréquence dû à des fluctuations aléatoires provenant de ses composants. Pour les caractériser expérimentalement la variance d'Allan est une méthode usuelle basée sur la différence entre deux échantillons successifs de la fréquence instantanée. Elle fonctionne bien pour les bruits dont le spectre est de type 1/f ou 1/f2. Mais elle diverge pour une croissance plus rapide près de la porteuse. La variance de B. Picinbono, quant à elle, est basée sur trois échantillons (différence du second ordre) et la pondération spectrale correspondante est adaptée à des divergences en 1/f3 ou 1/f4. C'est donc un excellent outil d'analyse des différentes sources de bruit d'un oscillateur. Ces deux variances, ainsi qu'une troisième prévue pour supprimer une dérive de fréquence, ont été comparées pour un oscillateur à quartz très stable à 10Mhz. Effectivement, la variance de B. Picinbono s'avère la plus efficace pour réduire les composantes très basses du bruit de fréquence et ses non stationnarités telles que dérive et marche au hasard

Optimal data partitioning, multispecies coalescent and Bayesian concordance analyses resolve early divergences of the grape family (Vitaceae)

Evolutionary rate heterogeneity and rapid radiations are common phenomena in organismal evolution and represent major challenges for reconstructing deep-level phylogenies. Here we detected substantial conflicts in and among data sets as well as uncertainty concerning relationships among lineages of Vitaceae from individual gene trees, supernetworks and tree certainty values. Congruent deep-level relationships of Vitaceae were retrieved by comprehensive comparisons of results from optimal partitioning analyses, multispecies coalescent approaches and the Bayesian concordance method. We found that partitioning schemes selected by PartitionFinder were preferred over those by gene or by codon position, and the unpartitioned model usually performed the worst. For a data set with conflicting signals, however, the unpartitioned model outperformed models that included more partitions, demonstrating some limitations to the effectiveness of concatenation for these data. For a transcriptome data set, fast coalescent methods (STAR and MP-EST) and a Bayesian concordance approach yielded congruent topologies with trees from the concatenated analyses and previous studies. Our results highlight that well-resolved gene trees are critical for the effectiveness of coalescent-based methods. Future efforts to improve the accuracy of phylogenomic analyses should emphasize the development of newmethods that can accommodate multiple biological processes and tolerate missing data while remaining computationally tractable. (C) The Willi Hennig Society 2017.National Natural Science Foundation of China [NNSF 31500179, 31590822, 31270268]; National Basic Research Program of China [2014CB954101]; National Science Foundation [DEB0743474]; Smithsonian Scholarly Studies Grant Program and the Endowment Grant Program; CAS/SAFEA International Partnership Program for Creative Research Teams; Laboratory of Analytical Biology of the National Museum of Natural History, Smithsonian Institution; Science and Technology Basic Work [2013FY112100]info:eu-repo/semantics/publishedVersio

Tectonic deformation of the Andes and the configuration of the subducted slab in central Peru: Results from a micro-seismic experiment

The vast majority of the microearthquakes recorded occurred to the east: on the Huaytapallana fault in the Eastern Cordillera or in the western margin of the sub-Andes. The sub-Andes appear to be the physiographic province subjected to the most intense seismic deformation. Focal depths for the crustal events here are as deep as 50 km, and the fault plane solutions, show thrust faulting on steep planes oriented roughly north-south. The Huaytapallana fault in the Cordillera Oriental also shows relatively high seismicity along a northeast-southwest trend that agrees with the fault scarp and the east dipping nodal plane of two large earthquakes that occurred on this fault in 1969. The recorded microearthquakes of intermediate depth show a flat seismic zone about 25 km thick at a depth of about 100 km. This agrees with the suggestion that beneath Peru the slab first dips at an angle of 30 deg to a depth of 100 km and then flattens following a quasi-horizontal trajectory. Fault plane solutions of intermediate depth microearthquakes have horizontal T axes oriented east-west

The configuration of the seismic zone and the downgoing slab in southern Peru

Using data from temporary networks of portable seismographs in southern Peru, we located 888 shallow and intermediate depth events near a proposed discontinuity in the seismic zone there. These events reveal a prominent contortion, instead of a discontinuity, that trends approximately N80°E, parallel to the direction of relative plate motion. North of about 15°S, the seismic zone beneath Peru is nearly horizontal, but south of about 15.5°S, it dips at about 25°. Volcanoes lie above the more steeply dipping zone where earthquakes occur between 120 and 140 km, and the volcanic line in southern Peru stops abruptly at the contortion

Remote Effects of Hippocampal Sclerosis on Effective Connectivity during Working Memory Encoding: A Case of Connectional Diaschisis?

Accumulating evidence suggests a role for the medial temporal lobe (MTL) in working memory (WM). However, little is known concerning its functional interactions with other cortical regions in the distributed neural network subserving WM. To reveal these, we availed of subjects with MTL damage and characterized changes in effective connectivity while subjects engaged in WM task. Specifically, we compared dynamic causal models, extracted from magnetoencephalographic recordings during verbal WM encoding, in temporal lobe epilepsy patients (with left hippocampal sclerosis) and controls. Bayesian model comparison indicated that the best model (across subjects) evidenced bilateral, forward, and backward connections, coupling inferior temporal cortex (ITC), inferior frontal cortex (IFC), and MTL. MTL damage weakened backward connections from left MTL to left ITC, a decrease accompanied by strengthening of (bidirectional) connections between IFC and MTL in the contralesional hemisphere. These findings provide novel evidence concerning functional interactions between nodes of this fundamental cognitive network and sheds light on how these interactions are modified as a result of focal damage to MTL. The findings highlight that a reduced (top-down) influence of the MTL on ipsilateral language regions is accompanied by enhanced reciprocal coupling in the undamaged hemisphere providing a first demonstration of “connectional diaschisis.

Remote Effects of Hippocampal Sclerosis on Effective Connectivity during Working Memory Encoding: A Case of Connectional Diaschisis?

Accumulating evidence suggests a role for the medial temporal lobe (MTL) in working memory (WM). However, little is known concerning its functional interactions with other cortical regions in the distributed neural network subserving WM. To reveal these, we availed of subjects with MTL damage and characterized changes in effective connectivity while subjects engaged in WM task. Specifically, we compared dynamic causal models, extracted from magnetoencephalographic recordings during verbal WM encoding, in temporal lobe epilepsy patients (with left hippocampal sclerosis) and controls. Bayesian model comparison indicated that the best model (across subjects) evidenced bilateral, forward, and backward connections, coupling inferior temporal cortex (ITC), inferior frontal cortex (IFC), and MTL. MTL damage weakened backward connections from left MTL to left ITC, a decrease accompanied by strengthening of (bidirectional) connections between IFC and MTL in the contralesional hemisphere. These findings provide novel evidence concerning functional interactions between nodes of this fundamental cognitive network and sheds light on how these interactions are modified as a result of focal damage to MTL. The findings highlight that a reduced (top-down) influence of the MTL on ipsilateral language regions is accompanied by enhanced reciprocal coupling in the undamaged hemisphere providing a first demonstration of “connectional diaschisis.

The Derived Allele of ASPM Is Associated with Lexical Tone Perception

The ASPM and MCPH1 genes have been implicated in the adaptive evolution of the human brain [Mekel-Bobrov N. et al., 2005. Ongoing adaptive evolution of ASPM, a brain size determinant in homo sapiens. Science 309; Evans P.D. et al., 2005. Microcephalin, a gene regulating brain size, continues to evolve adaptively in humans. Science 309]. Curiously, experimental attempts have failed to connect the implicated SNPs in these genes with higher-level brain functions. These results stand in contrast with a population-level study linking the population frequency of their alleles with the tendency to use lexical tones in a language [Dediu D., Ladd D.R., 2007. Linguistic tone is related to the population frequency of the adaptive haplogroups of two brain size genes, ASPM and microcephalin. Proc. Natl. Acad. Sci. U.S.A. 104]. In the present study, we found a significant correlation between the load of the derived alleles of ASPM and tone perception in a group of European Americans who did not speak a tone language. Moreover, preliminary results showed a significant correlation between ASPM load and hemodynamic responses to lexical tones in the auditory cortex, and such correlation remained after phonemic awareness, auditory working memory, and non-verbal IQ were controlled. As in previous studies, no significant correlation between ASPM and cognitive measures were found. MCPH1 did not correlate with any measures. These results suggest that the association between the recently derived allele of ASPM is likely to be specific and is tied to higher level brain functions in the temporal cortex related to human communication