Predictive analysis of maxillary canine impaction through sella turcica bridging, ponticulus posticus calcification, and lateral incisor anomalies: a retrospective observational study

Maxillary canine impaction is an increasing dental anomaly and is often related to other dento-skeletal anomalies. The aim of this work is to support the clinician in evaluating the relationship between a displaced maxillary canine and clinical (the features of lateral incisors)/skeletal (ponticulus posticus and sella turcica bridging) anomalies through orthopanoramic radiographs, lateral cephalograms, and plaster casts to identify the parameters that best predict maxillary canine impaction. A retrospective observational study was carried out on the analysis of the medical records, radiographic findings (panoramic radiographs and lateral cephalograms), and plaster casts of 203 orthodontic patients divided into a case group, with at least one impacted maxillary canine, and a control group, without an impaction. A chi-square test and logistic regression analysis were used to analyze the data. A statistically significant association was found between the impaction of the maxillary canine and the female sex, the bridging of the sella turcica, the ponticulus posticus calcification, and the anomaly of the lateral incisor; a logistic regression revealed that these significant variables were found to be positive predictors of impacted maxillary canines, particularly in reference to the impaction in the palatal area. Finding one of these clinical and radiographic elements can represent a predictive sign of the possible impaction of the maxillary canine

Comparision of profile macro-estethic perception among orthodontists, dentistry students, orthodontic patients and surgical orthodontic patients

The patient?s needs should guide the orthodontist in choosing the most appropriate therapy. The purpose of the present survey was to compare the esthetic perception of the facial profile by orthodontists (O), dentistry students (DS), orthodontic patient

Impact of renin-angiotensin system inhibitors on mortality during the COVID Pandemic among STEMI patients undergoing mechanical reperfusion : Insight from an international STEMI registry

Background: Concerns have been raised on a potential interaction between renin-angiotensin system inhibitors (RASI) and the susceptibility to coronavirus disease 2019 (COVID-19). No data have been so far reported on the prognostic impact of RASI in patients suffering from ST-elevation myocardial infarction (STEMI) during COVID-19 pandemic, which was the aim of the present study. Methods: STEMI patients treated with primary percutaneous coronary intervention (PPCI) and enrolled in the ISACS-STEMI COVID-19 registry were included in the present sub-analysis and divided according to RASI therapy at admission. Results: Our population is represented by 6095 patients, of whom 3654 admitted in 2019 and 2441 in 2020. No difference in the prevalence of SARSCoV2 infection was observed according to RASI therapy at admission (2.5% vs 2.1%, p = 0.5), which was associated with a significantly lower mortality (adjusted OR [95% CI]=0.68 [0.51 & ndash;0.90], P = 0.006), confirmed in the analysis restricted to 2020 (adjusted OR [95% CI]=0.5[0.33 & ndash;0.74], P = 0.001). Among the 5388 patients in whom data on in-hospital medication were available, in-hospital RASI therapy was associated with a significantly lower mortality (2.1% vs 16.7%, OR [95% CI]=0.11 [0.084 & ndash;0.14], p < 0.0001), confirmed after adjustment in both periods. Among the 62 SARSCoV-2 positive patients, RASI therapy, both at admission or in-hospital, showed no prognostic effect. Conclusions: This is the first study to investigate the impact of RASI therapy on the prognosis and SARSCoV2 infection of STEMI patients undergoing PPCI during the COVID-19 pandemic. Both pre-admission and in-hospital RASI were associated with lower mortality. Among SARSCoV2-positive patients, both chronic and in-hospital RASI therapy showed no impact on survival.Peer reviewe

Computer-guided palatal canine disimpaction: a technical note

Aim: To present a minimally invasive approach to solve the impaction of palatal canines using computer-guided orthodontic miniscrews. Materials and methods: Miniscrew-supported appliances for palatal canine disimpaction are performed with CAD/CAM technology. With adequate software, it is possible to match the STL files of the dental arch with the DICOM images of the maxilla, previously transformed into STL files. The ideal points for miniscrew insertion can be identified on the STL 3D model file on the basis of the width and thickness of the palatal vault. A software application allows for the design of the surgical guide, which is printed using a 3D printer. The virtual position of the planned miniscrews is transferred onto a printed dental cast on which the orthodontic device is realized. On the day of surgery, both the surgical guide and the orthodontic appliance are ready for use. Results: Miniscrew insertion and palatal canine disimpaction can be achieved in one surgical procedure. Conclusion: The use of computer-guided skeletal anchorage allows for both the reduction of the biomechanical side effects typical of conventional treatment and the risk of damaging adjacent anatomical structures, increasing the effectiveness of treatment. Controlled clinical trials are necessary to evaluate more fully any advantages of this minimally invasive technique

Surgery for Anomalous Aortic Origin of Coronary Arteries: Technical Safeguards and Pitfalls

nomalous aortic origin of a coronary artery (AAOCA) is reported as the second leading cause of sudden cardiac death in otherwise healthy young individuals. Several surgical studies have reported a shallow operative risk, describing repair as safe and effective with short or medium-term follow-up. However, surgical repair can also be associated with a high risk of complications. Numerous repair techniques have been described in the literature, but each technique's indications and limitations are often not well-understood or understated. Since explicit technical knowledge of the most appropriate surgical technique is highly desirable, we sought to thoroughly and clearly outline the safeguards and pitfalls of the most common surgical techniques used to repair AAOCA

Inclusione del canino mascellare e anomalie dentali e scheletriche associate: uno studio retrospettivo. Maxillary canine impaction and the association with dental and skeletal anomalies: a retrospective study

OBIETTIVI Obiettivo dello studio è indagare l’associazione tra inclusione del canino mascellare e anomalie dentarie geneticamente determinate, caratteristiche craniofacciali e familiarità positiva. MATERIALI E METODI 100 soggetti con l’inclusione del canino mascellare sono stati inseriti in un gruppo di studio (GS) e confrontati con un gruppo di controllo (GC) di 100 soggetti senza inclusione del canino mascellare. Sono state utilizzate la statistica descrittiva, il test del chi-quadro e il t-test di Student. RISULTATI Il confronto tra GS e GC ha mostrato una differenza statisticamente significativa per l’anomalia dell’incisivo laterale (P = 0,015), l’agenesia dei terzi molari (P = 0,015), per i valori angolari di SNB (P = 0,027), ANB (P = 0,043) e per la familiarità di inclusione canina mascellare (P <0,01). CONCLUSIONI Le associazioni tra l’inclusione del canino mascellare, le anomalie dentali e la familiarità positiva suggeriscono una relazione tra l’inclusione del canino e alcune anomalie dentali geneticamente determinate

Cetacean Morbillivirus and Toxoplasma gondii Co-infection in Mediterranean Monk Seal Pup, Italy

A Mediterranean monk seal (Monachus monachus) pup from the southern Adriatic coast of Italy showed cetacean morbillivirus (CeMV) and disseminated Toxoplasma gondii co-infection, which probably resulted from CeMV-induced immunosuppression. These findings are of concern for the conservation of this critically endangered species

Effectiveness and long-term durability of autologous fat transplant for HIV-related face lipoatrophy.

Autologous Fat Transplat (AFT) according to Coleman tachnique is an effective option for surgical treatment of HIV-related facial lipoatrophy; nevertheless, both patients and surgeons are often concerned about durability of this procedure in the fear of early fat reabsorption in the recipient area. The purpose of this study was to evaluate effectiveness and log-term durability of AFT with a 104 - week follow up in patients who were treated with single surgical procedure and in those who needed lipofilling reintervention or aesthetic correction with subcutaneous filler