Erratum to: The study of cardiovascular risk in adolescents – ERICA: rationale, design and sample characteristics of a national survey examining cardiovascular risk factor profile in Brazilian adolescents

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Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome : Insights from the LUNG SAFE study

Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods: In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≥ 0.60 during hyperoxemia). Results: Of 2005 patients that met the inclusion criteria, 131 (6.5%) were hypoxemic (PaO2 < 55 mmHg), 607 (30%) had hyperoxemia on day 1, and 250 (12%) had sustained hyperoxemia. Excess FIO2 use occurred in 400 (66%) out of 607 patients with hyperoxemia. Excess FIO2 use decreased from day 1 to day 2 of ARDS, with most hyperoxemic patients on day 2 receiving relatively low FIO2. Multivariate analyses found no independent relationship between day 1 hyperoxemia, sustained hyperoxemia, or excess FIO2 use and adverse clinical outcomes. Mortality was 42% in patients with excess FIO2 use, compared to 39% in a propensity-matched sample of normoxemic (PaO2 55-100 mmHg) patients (P = 0.47). Conclusions: Hyperoxemia and excess oxygen use are both prevalent in early ARDS but are most often non-sustained. No relationship was found between hyperoxemia or excessive oxygen use and patient outcome in this cohort. Trial registration: LUNG-SAFE is registered with ClinicalTrials.gov, NCT02010073publishersversionPeer reviewe

A presença de estudantes: o encontro de museus e escola no Brasil a partir da década de 50 do século XX The students presence: the interface between museums and schools in Brazil the 1950's

O texto tem como foco a história da museologia no Brasil, colocando em questão as relações entre museus e educação nos anos de 1950. Nesse sentido, procura demonstrar como a questão da relação entre museus e educação contribuiu para renovar o conceito de museus e o perfil dos profissionais de museus no Brasil. A produção intelectual é a fonte principal de pesquisa, especialmente livros e artigos em revistas publicados na época. A pesquisa ressalta a importância da organização do Conselho Internacional de Museus no Brasil, culminando com o seminário que aconteceu no Rio de Janeiro em 1958, acompanhado pelas not��cias na imprensa diária. Ao final, o trabalho procura caracterizar como o debate sobre museus e educação se renovou na década de 1980 com os conceitos de museu integral e educação patrimonial.<br>The history of museology in Brazil is the focus of this paper, questioning the relation between museums and education in the 1950´s years. In this sense, tries to demonstrate how the debate about museums and education contributed to renovate the concept of museum and to renovate the profile of the museums professionals. The intellectual production was the main source of the research, specially books and journals, published at that time. The research highlights the importance of the organization in Brazil of the national committee of the International Council of Museums, culminating with the seminar that happened in Rio de Janeiro in 1958, followed by the diary press. At the end, the paper characterizes how the debate about museums and education was renovated in the 1980´s with the new concepts of integral museums and heritage education