Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

1979 breeding bird censuses and summary of 1977-1979 results

As part of a program to characterize the plant and animal life of the Laboratory site and the surrounding region, the two breeding bird censuses originated in 1977 were continued in 1979. Twelve census trips were made to the BNL plot and 10 to the Westhampton plot by seven volunteer observers. Comparisons of data from the three years showed that the number of territorial males on the BNL plot did not change significantly, but the number of breeding species showed a continuous decline, from 18 to 10. Little change in the number of territorial males or in species composition occurred in the Westhampton plot

Vertical Variation in Pollen Abundance in North-Central London

Pollen data from three samplers located at heights of 0.5m, 10m and 55 m were used to investigate vertical differences in pollen abundance in North-Central London. Weekly accumulative counts for all pollen types were collected from February to September 1988. Distinct variations in abundance between the sites were recorded for some pollen taxa. For example,Gramineae recorded greater abundance at the higher sampling position. Other pollen types, includingPlatanus, were recorded at consistently greater abundance at the 10 m height compared to the 55 m level. Significant differences between the pollen counts at these two heights are discussed in relation to pollen source area, the specific gravity of the pollen grain, airflow patterns of the urban area and the weather conditions affecting pollen dispersal. Tracer experiments using Lycopodium spores were employed to investigate dispersal patterns to all three sampling heights. The results from these trials are used to assist in the interpretation of data from the depositional samplers. The study reported in this paper forms part of a wider survey of 14 sampling sites examining spatial variations in pollen abundance

Atmospheric sciences division. Annual report, fiscal year 1981

The research activities of the Atmospheric Sciences Division of the Department of Energy and Environment for FY 1981 are presented. Facilities and major items of equipment are described. Research programs are summarized in three categories, modeling, field and laboratory experiments and data management and analysis. Each program is also described individually with title, principal investigator, sponsor and funding levels for FY 1981 and FY 1982. Future plans are summarized. Publications for FY 1981 are listed with abstracts. A list of personnel is included

Atmospheric diffusion from an off-shore site

From symposium on the physical behavior of radioactive containment in the atmosphere; Vienna, Austria (12 Nov 1973). Analysis of the fate of airborne effluerts from a nuclear reactor at an off-shore site requires a better understanding of overwater atmospheric dispersion than currently exists. For this reason, a diffus1on study was undertaken off the south shore of Long Island, New York, about 100 km from New York City. This study is using tracer material (oil fog smoke) released from an anchored boat. Measurements of mean wind, turbulence, and temperature are made on portable towers on the beach, from an aircraft, and aboard the source boat. Plume geometry 1s documented by photography and from quantitative concentration measurements. Experiments under a variety of meteorolog1cal conditions indicate that over-water dispers1on is very sensitive to meteorological conditions. From measured is significantly less than over land, particularly when the onshore flow is due to the sea breeze. This is because of the low aerodynamic roughness of the water, and because low level stable conditions are established because the water is at lower temperature than the air. Crosswind standard deviations of the plume a factor two less than the prediction of Pasquill category F have been observed at the shore with the source 6 km off shore. (auth