76 research outputs found
Non-equilibrium Superconductivity and Quasiparticle Dynamics studied by Photo Induced Activation of Mm-Wave Absorption (PIAMA)
We present a study of non-equilibrium superconductivity in DyBa2Cu3O7-d using
photo induced activation of mm-wave absorption (PIAMA). We monitor the time
evolution of the thin film transmissivity at 5 cm-1 subject to pulsed infrared
radiation. In addition to a positive bolometric signal we observe a second,
faster, decay with a sign opposite to the bolometric signal for T>40 K. We
attribute this to the unusual properties of quasi-particles residing near the
nodes of an unconventional superconductor, resulting in a strong enhancement of
the recombination time.Comment: 4 pages, REVTeX, Submitted to Phys. Rev. Letter
Allergic sensitization: screening methods
Experimental in silico, in vitro, and rodent models for screening and predicting protein sensitizing potential are discussed, including whether there is evidence of new sensitizations and allergies since the introduction of genetically modified crops in 1996, the importance of linear versus conformational epitopes, and protein families that become allergens. Some common challenges for predicting protein sensitization are addressed: (a) exposure routes; (b) frequency and dose of exposure; (c) dose-response relationships; (d) role of digestion, food processing, and the food matrix; (e) role of infection; (f) role of the gut microbiota; (g) influence of the structure and physicochemical properties of the protein; and (h) the genetic background and physiology of consumers. The consensus view is that sensitization screening models are not yet validated to definitively predict the de novo sensitizing potential of a novel protein. However, they would be extremely useful in the discovery and research phases of understanding the mechanisms of food allergy development, and may prove fruitful to provide information regarding potential allergenicity risk assessment of future products on a case by case basis. These data and findings were presented at a 2012 international symposium in Prague organized by the Protein Allergenicity Technical Committee of the International Life Sciences Institute’s Health and Environmental Sciences Institute
Optical creation of vibrational intrinsic localized modes in anharmonic lattices with realistic interatomic potentials
Using an efficient optimal control scheme to determine the exciting fields,
we theoretically demonstrate the optical creation of vibrational intrinsic
localized modes (ILMs) in anharmonic perfect lattices with realistic
interatomic potentials. For systems with finite size, we show that ILMs can be
excited directly by applying a sequence of femtosecond visible laser pulses at
THz repetition rates. For periodic lattices, ILMs can be created indirectly via
decay of an unstable extended lattice mode which is excited optically either by
a sequence of pulses as described above or by a single picosecond far-infrared
laser pulse with linearly chirped frequency. In light of recent advances in
experimental laser pulse shaping capabilities, the approach is experimentally
promising.Comment: 20 pages, 7 eps figures. Accepted, Phys. Rev.
Current challenges facing the assessment of the allergenic capacity of food allergens in animal models
Food allergy is a major health problem of increasing concern. The insufficiency of protein sources for human nutrition in a world with a growing population is also a significant problem. The introduction of new protein sources into the diet, such as newly developed innovative foods or foods produced using new technologies and production processes, insects, algae, duckweed, or agricultural products from third countries, creates the opportunity for development of new food allergies, and this in turn has driven the need to develop test methods capable of characterizing the allergenic potential of novel food proteins. There is no doubt that robust and reliable animal models for the identification and characterization of food allergens would be valuable tools for safety assessment. However, although various animal models have been proposed for this purpose, to date, none have been formally validated as predictive and none are currently suitable to test the allergenic potential of new foods. Here, the design of various animal models are reviewed, including among others considerations of species and strain, diet, route of administration, dose and formulation of the test protein, relevant controls and endpoints measured
Science and society in education
This booklet is for teachers who want to expand their
teaching approaches to include socio-scientific issues
which enrich and give meaning to core scientific principles.
It is meant to enhance young people’s curiosity about the
social and scientific world and raise important questions
about issues which affect their lives. We call this approach
Socio-Scientific Inquiry-Based Learning, or ‘SSIBL’ for
short. Chapters 1 and 2 present an introduction to the
theoretical background of SSIBL. In chapter 3, SSIBL will
be approached from a classroom perspective, providing a
simplified version of the framework and showing teaching
examples
Effects of a Science Education Module on Attitudes towards Modern Biotechnology of Secondary School Students
On the Roots of Difficulties in Learning about Cell Division: Process‐based analysis of students’ conceptual development in teaching experiments
Statistical energy analysis, energy distribution models and system modes
Expressions for the energy influence coefficients of a built-up structure are found in terms of the modes of the whole structure. These coefficients relate the time and frequency average energies of the subsystems to the subsystem input powers. Rain-on-the-roof excitation over a frequency band is assumed. It is then seen that the system can be described by an SEA model only if a particular condition involving the mode shapes of the system is satisfied. Broadly, the condition holds if the mode shapes of the modes in the frequency band of excitation are, on average, typical enough of all the modes of the system in terms of the distribution of energy throughout the system. If this condition is satisfied then the system can be modelled using an "quasi-SEA" approach, irrespective of the level of damping or of the strength of coupling. However, the resulting model need not be of a proper SEA form, and in particular the indirect coupling loss factors may not be negligible
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