Multi-band optical variability of three TeV Blazars on Diverse Timescales

We present our optical photometric observations of three TeV blazars, PKS 1510-089, PG 1553+113 and Mrk 501 taken using two telescopes in India, one in Bulgaria, one in Greece and one in Serbia during 2012 - 2014. These observations covered a total of 95 nights with a total of 202 B filter frames, 247 images in V band, 817 in R band while 229 images were taken in the I filter. This work is focused on multi-band flux and colour variability studies of these blazars on diverse timescales which are useful in understanding the emission mechanisms. We studied the variability characteristics of above three blazars and found all to be active over our entire observational campaigns. We also searched for any correlation between the brightness of the sources and their colour indices. During the times of variability, no significant evidence for the sources to display spectral changes correlated with magnitude was found on timescales of a few months. We briefly discuss the possible physical mechanisms most likely responsible for the observed flux variability.Comment: 11 pages, 7 figures, 9 tables. Accepted for publication in MNRA

Entirely off-grid and solar-powered DNA sequencing of microbial communities during an ice cap traverse expedition

Microbial communities in remote locations remain under-studied. This is particularly true on glaciers and icecaps, which cover approximately 11% of the Earth’s surface. The principal reason for this is the inaccessibility of most of these areas due to their extreme isolation and challenging environmental conditions. While remote research stations have significantly lowered the barrier to studying the microbial communities on icecaps, their use has led to a bias for data collection in the near vicinity of these institutions. Here, miniaturisation of a DNA sequencing lab suitable for off-grid metagenomic studies is demonstrated. Using human power alone, this lab was transported across Europe’s largest ice cap (Vatnajökull, Iceland) by ski and sledge. After 11 days of unsupported polar-style travel, a metagenomic study of a geothermal hot spring gorge was conducted on the remote northern edge of the ice cap. This tent-based metagenomic study resulted in over 24 h of Nanopore sequencing, powered by solar power alone. This study demonstrates the ability to conduct DNA sequencing in remote locations, far from civilised resources (mechanised transport, external power supply, internet connection, etc.), whilst greatly reducing the time from sample collection to data acquisition

Rolling friction of a viscous sphere on a hard plane

A first-principle continuum-mechanics expression for the rolling friction coefficient is obtained for the rolling motion of a viscoelastic sphere on a hard plane. It relates the friction coefficient to the viscous and elastic constants of the sphere material. The relation obtained refers to the case when the deformation of the sphere $\xi$ is small, the velocity of the sphere $V$ is much less than the speed of sound in the material and when the characteristic time $\xi/V$ is much larger than the dissipative relaxation times of the viscoelastic material. To our knowledge this is the first ``first-principle'' expression of the rolling friction coefficient which does not contain empirical parameters.Comment: 6 pages, 2 figure

Organizational learning and emotion: constructing collective meaning in support of strategic themes

Missing in the organizational learning literature is an integrative framework that reflects the emotional as well as the cognitive dynamics involved. Here, we take a step in this direction by focusing in depth over time (five years) on a selected organization which manufactures electronic equipment for the office industry. Drawing on personal construct theory, we define organizational learning as the collective re-construal of meaning in the direction of strategically significant themes. We suggest that emotions arise as members reflect on progress or lack of progress in achieving organizational learning. Our evidence suggests that invalidation – where organizational learning fails to correspond with expectations – gives rise to anxiety and frustration, while validation – where organizational learning is aligned with or exceeds expectations – evokes comfort or excitement. Our work aims to capture the key emotions involved as organizational learning proceeds

An ICA with reference approach in identification of genetic variation and associated brain networks

To address the statistical challenges associated with genome-wide association studies, we present an independent component analysis (ICA) with reference approach to target a specific genetic variation and associated brain networks. First, a small set of single nucleotide polymorphisms (SNPs) are empirically chosen to reflect a feature of interest and these SNPs are used as a reference when applying ICA to a full genomic SNP array. After extracting the genetic component maximally representing the characteristics of the reference, we test its association with brain networks in functional magnetic resonance imaging (fMRI) data. The method was evaluated on both real and simulated datasets. Simulation demonstrates that ICA with reference can extract a specific genetic factor, even when the variance accounted for by such a factor is so small that a regular ICA fails. Our real data application from 48 schizophrenia patients (SZs) and 40 healthy controls (HCs) include 300K SNPs and fMRI images in an auditory oddball task. Using SNPs with allelic frequency difference in two groups as a reference, we extracted a genetic component that maximally differentiates patients from controls (p < 4 × 10−17), and discovered a brain functional network that was significantly associated with this genetic component (p < 1 × 10−4). The regions in the functional network mainly locate in the thalamus, anterior and posterior cingulate gyri. The contributing SNPs in the genetic factor mainly fall into two clusters centered at chromosome 7q21 and chromosome 5q35. The findings from the schizophrenia application are in concordance with previous knowledge about brain regions and gene function. All together, the results suggest that the ICA with reference can be particularly useful to explore the whole genome to find a specific factor of interest and further study its effect on brain

Polar Topside Ionosphere During Geomagnetic Storms: Comparison of ISIS-II With TDIM

Space weather deposits energy into the high polar latitudes, primarily via Joule heating that is associated with the Poynting flux electromagnetic energy flow between the magnetosphere and ionosphere. One way to observe this energy flow is to look at the ionospheric electron density profile (EDP), especially that of the topside. The altitude location of the ionospheric peak provides additional information on the net field‐aligned vertical transport at high latitudes. To date, there have been few studies in which physics‐based ionospheric model storm simulations have been compared with topside EDPs. A rich database of high‐latitude topside ionograms obtained from polar orbiting satellites of the International Satellites for Ionospheric Studies (ISIS) program exists but has not been utilized in comparisons with physics‐based models. Of specific importance is that the Alouette/ISIS topside EDPs spanned the timeframe from 1962 to 1983, a period that experienced very large geomagnetic storms. We use a physics‐based ionospheric model, the Utah State University Time Dependent Ionospheric Model (TDIM), to simulate ionospheric EDPs for quiet and storm high‐latitude passes of ISIS‐II for two geomagnetic storms. This initial study finds that under quiet conditions there is good agreement between model and observations. During disturbed conditions, however, a large difference is seen between model and observations. The model limitation is probably associated with the inability of its topside boundary to replicate strong outflow conditions. As a result, modeling of the ionospheric outflows needs to be extended well into the magnetosphere, thereby moving the upper boundary much higher and requiring the use of polar wind models

ANALYSIS OF THE DIURNAL EXPRESSION PATTERNS OF THE TOMATO CHLOROPHYLL alb BINDING PROTEIN GENES. INFLUENCE OF LIGHT and CHARACTERIZATION OF THE GENE FAMILY *

Steady-state mRNA levels of the chlorophyll alb binding ( cab ) proteins oscillate substantially during a diurnal cycle in tomato leaves. This accumulation pattern is also observed in complete darkness, supporting the hypothesis that the expression of cab genes is at least partially regulated by an endogenous rhythm (“biological clock”). The amplitude of the cab mRNA accumulation is dependent on the duration of illumination and the circadian phase in which light was applied to the tomato plants. These results at the molecular level correlate well with the photoperiodic phenomenon. The characterization of the expression pattern of individual members of the cab gene family was attempted. Distinct primer extension products were detected using specific oligonucleotides homologous to the cab 1, cab 4, cab 5 and cab 8 genes. Based on this analysis the transcription start sites of these genes were determined to be between position -70 and -9 upstream of the ATG codon. During the diurnal cycle the cab 1 and cab 4 genes exhibit the same expression pattern; no transcripts detected at 3 and 6 a.m., maximum mRNA levels were measured at noon and decreasing levels in the afternoon.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74852/1/j.1751-1097.1990.tb01752.x.pd

Sources and sinks separating domains of left- and right-traveling waves: Experiment versus amplitude equations

In many pattern forming systems that exhibit traveling waves, sources and sinks occur which separate patches of oppositely traveling waves. We show that simple qualitative features of their dynamics can be compared to predictions from coupled amplitude equations. In heated wire convection experiments, we find a discrepancy between the observed multiplicity of sources and theoretical predictions. The expression for the observed motion of sinks is incompatible with any amplitude equation description.Comment: 4 pages, RevTeX, 3 figur

Multiband optical variability of the blazar OJ 287 during its outbursts in 2015 -- 2016

We present recent optical photometric observations of the blazar OJ 287 taken during September 2015 -- May 2016. Our intense observations of the blazar started in November 2015 and continued until May 2016 and included detection of the large optical outburst in December 2016 that was predicted using the binary black hole model for OJ 287. For our observing campaign, we used a total of 9 ground based optical telescopes of which one is in Japan, one is in India, three are in Bulgaria, one is in Serbia, one is in Georgia, and two are in the USA. These observations were carried out in 102 nights with a total of ~ 1000 image frames in BVRI bands, though the majority were in the R band. We detected a second comparably strong flare in March 2016. In addition, we investigated multi-band flux variations, colour variations, and spectral changes in the blazar on diverse timescales as they are useful in understanding the emission mechanisms. We briefly discuss the possible physical mechanisms most likely responsible for the observed flux, colour and spectral variability.Comment: 11 pages, 6 figures, 4 tables; Accepted for publication in MNRA