264 research outputs found
Toward a User Commitment Continuum
User commitment to a new information system is critical to its success. But what does this mean? One explanatory theory is the Technology Acceptance Model (TAM), which has gained wide recognition, but has also been criticized for its inability to account for temporal and contextual differences as well as its failure to consider how user commitment grows and changes with system use. This paper suggests that âuser commitmentâ is not a binary proposition, but rather is better described as a range of values on a continuum. We propose such a model with at least four major components
Dynamics of Particles Deposition on a Disordered Substrate: II. Far-from Equilibrium Behavior. -
The deposition dynamics of particles (or the growth of a rigid crystal) on a
disordered substrate at a finite deposition rate is explored. We begin with an
equation of motion which includes, in addition to the disorder, the periodic
potential due to the discrete size of the particles (or to the lattice
structure of the crystal) as well as the term introduced by Kardar, Parisi, and
Zhang (KPZ) to account for the lateral growth at a finite growth rate. A
generating functional for the correlation and response functions of this
process is derived using the approach of Martin, Sigga, and Rose. A consistent
renormalized perturbation expansion to first order in the non-Gaussian
couplings requires the calculation of diagrams up to three loops. To this order
we show, for the first time for this class of models which violates the the
fluctuation-dissipation theorem, that the theory is renormalizable. We find
that the effects of the periodic potential and the disorder decay on very large
scales and asymptotically the KPZ term dominates the behavior. However, strong
non-trivial crossover effects are found for large intermediate scales.Comment: 52 pages & 17 Figs in uucompressed file. UR-CM 94-090
Differential response of human basophil activation markers: a multi-parameter flow cytometry approach
<p>Abstract</p> <p>Background</p> <p>Basophils are circulating cells involved in hypersensitivity reactions and allergy but many aspects of their activation, including the sensitivity to external triggering factors and the molecular aspects of cell responses, are still to be focused. In this context, polychromatic flow cytometry (PFC) is a proper tool to investigate basophil function, as it allows to distinguish the expression of several membrane markers upon activation in multiple experimental conditions. </p> <p>Methods</p> <p>Cell suspensions were prepared from leukocyte buffy coat of K2-EDTA anticoagulated blood specimens; about 1500-2500 cellular events for each tested sample, gated in the lymphocyte CD45dim area and then electronically purified as HLADRnon expressing/CD123bright, were identified as basophilic cells. Basophil activation with fMLP, anti-IgE and calcium ionophore A23187 was evaluated by studying up-regulation of the indicated membrane markers with a two-laser six-color PFC protocol.</p> <p>Results</p> <p>Following stimulation, CD63, CD13, CD45 and the ectoenzyme CD203c up-regulated their membrane expression, while CD69 did not; CD63 expression occurred immediately (within 60 sec) but only in a minority of basophils, even at optimal agonist doses (in 33% and 14% of basophils, following fMLP and anti-IgE stimulation respectively). CD203c up-regulation occurred in the whole basophil population, even in CD63non expressing cells. Dose-dependence curves revealed CD203c as a more sensitive marker than CD63, in response to fMLP but not in response to anti-IgE and to calcium ionophore.</p> <p>Conclusion</p> <p>Use of polychromatic flow cytometry allowed efficient basophil electronic purification and identification of different behaviors of the major activation markers. The simultaneous use of two markers of activation and careful choice of activator are essential steps for reliable assessment of human basophil functions.</p
Understanding management gurus and historical narratives: The benefits of a historic turn in management and organization studies
A historic turn in organization studies requires a basic theoretical understanding of âdoing historyâ and an appreciation of the centrality of narrative in history. Following the cultural turn in history, narrativist historians and philosophers of history such as Hayden White, Frank Ankersmit and Paul Ricoeur have made the case that narrative is an essential and unavoidable component in history. We demonstrate the persuasive capacity of narrative through a narrativist critique of three best-selling âmanagement gurusâ. This analysis illustrates the following: (1) the narrative features of popular organizational theories; (2) the basis of the success of guru literature; and (3) why gurus and organizational scientists themselves do not understand the narratological mechanisms behind their success. Finally, we maintain that historical narrativism offers the possibility for positioning organizational history as a highly relevant field for management academics, gurus and even managers, providing support for a historic turn
Fashion retailing â past, present and future
This issue of Textile Progress reviews the way that fashion retailing has developed as a result of the application of the World Wide Web and information and communications technology (ICT) by fashion-retail companies. The review therefore first considers how fashion retailing has evolved, analysing retail formats, global strategies, emerging and developing economies, and the factors that are threatening and driving growth in the fashion-retail market. The second part of the review considers the emergence of omni-channel retailing, analysing how retail has progressed and developed since the adoption of the Internet and how ICT initiatives such as mobile commerce (m-commerce), digital visualisation online, and in-store and self-service technologies have been proven to support the progression and expansion of fashion retailing. The paper concludes with recommendations on future research opportunities for gaining a better understanding of the impacts of ICT and omni-channel retailing, through which it may be possible to increase and develop knowledge and understanding of the way the sector is developing and provide fresh impetus to an already-innovative and competitive industr
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