Evaluation of Plastic Depletion by Replacing Eco-Dining Palm-Plates (Areca Catechu)

Background: In today's world, take-away materials predominantly consist of non-biodegradable plastics, known for their longevity and the release of harmful toxins during decomposition. To tackle this problem, the following article delves into the advantages and substitutes for plastic takeaway utensils and tableware, focusing on products made from palm (areca) and coconut tree by-products. It delves into the revival of traditional methods and knowledge rummage-sale in the southern then central parts of the India to create sustainable dining products. The article includes a market analysis, design considerations, life cycle analysis, and in-depth research on fabrication. Disposable plates, such as those made it from the polythene, polypropylene, polystyrene, polycarbonate, and polyvinyl chloride pose health risks, As a result of the release of noxious compounds, including melamine, vinyl chloride, biphenyl A, and phthalates. Therefore, an increasing trend is emerging in favour of utilizing use and throw plates crafted from plant leaves, which are both renewable and decomposable, however it is offering substantial antioxidant and medicinal properties. Results: In India, the classical way of using leaf dining plates carries profound cultural values, religious beliefs, medicinal, and socio-economic significance. The art of crafting these leaf plates serves as a livelihood for tribal communities residing in the states such as Orissa, Madhya Pradesh, Chhattisgarh, and Andhra Pradesh, These palm plates hold a crucial role in the offerings presented during religious rituals (Naivedyam) and the distribution of Prasadam to devotees. They find extensive use in serving meals at weddings, religious festivities, communal gatherings, and a wide array of other events. India embraces a variety of plant leaves not just as dining plates but also for their utility in wrapping, steaming, grilling, frying, and as materials for food packaging. Conclusion: In summary, biodegradable palm plates possess significant promise in the global market, granted they adhere to quality, design criteria. To promote the continued use of Leaf plates and discourage the adoption of plastic alternatives, it is imperative for the government to establish requisite regulations, which local authorities should rigorously enforce. Furthermore, spreading awareness among school and college students regarding the importance of these leaf plates is pivotal for nurturing their sustained adoption

Quasar feedback survey: molecular gas affected by central outflows and by ∼10-kpc radio lobes reveal dual feedback effects in \u27radio quiet\u27 quasars

\ua9 The Author(s) 2023. Published by Oxford University Press on behalf of Royal Astronomical Society. We present a study of molecular gas, traced via CO (3–2) from Atacama Large Millimeter/submillimeter Array data, of four z < 0.2, ‘radio quiet’, type 2 quasars (Lbol ∼ 1045.3–1046.2 erg s−1; L1.4 GHz ∼ 1023.7–1024.3 WHz−1). Targets were selected to have extended radio lobes (≥ 10 kpc), and compact, moderate-power jets (1–10 kpc; Pjet ∼ 1043.2–1043.7 erg s−1). All targets show evidence of central molecular outflows, or injected turbulence, within the gas discs (traced via high-velocity wing components in CO emission-line profiles). The inferred velocities (Vout = 250–440 km s−1) and spatial scales (0.6–1.6 kpc), are consistent with those of other samples of luminous low-redshift active galactic nuclei. In two targets, we observe extended molecular gas structures beyond the central discs, containing 9–53 per cent of the total molecular gas mass. These structures tend to be elongated, extending from the core, and wrap-around (or along) the radio lobes. Their properties are similar to the molecular gas filaments observed around radio lobes of, mostly ‘radio loud’, brightest cluster galaxies. They have the following: projected distances of 5–13 kpc; bulk velocities of 100–340 km s−1; velocity dispersion of 30–130 km s−1; inferred mass outflow rates of 4–20 M⊙ yr−1; and estimated kinetic powers of 1040.3–1041.7 erg s−1. Our observations are consistent with simulations that suggest moderate-power jets can have a direct (but modest) impact on molecular gas on small scales, through direct jet–cloud interactions. Then, on larger scales, jet-cocoons can push gas aside. Both processes could contribute to the long-term regulation of star formation

Predicting optical coherence tomography-derived diabetic macular edema grades from fundus photographs using deep learning

Center-involved diabetic macular edema (ci-DME) is a major cause of vision loss. Although the gold standard for diagnosis involves 3D imaging, 2D imaging by fundus photography is usually used in screening settings, resulting in high false-positive and false-negative calls. To address this, we train a deep learning model to predict ci-DME from fundus photographs, with an ROC–AUC of 0.89 (95% CI: 0.87–0.91), corresponding to 85% sensitivity at 80% specificity. In comparison, retinal specialists have similar sensitivities (82–85%), but only half the specificity (45–50%, p < 0.001). Our model can also detect the presence of intraretinal fluid (AUC: 0.81; 95% CI: 0.81–0.86) and subretinal fluid (AUC 0.88; 95% CI: 0.85–0.91). Using deep learning to make predictions via simple 2D images without sophisticated 3D-imaging equipment and with better than specialist performance, has broad relevance to many other applications in medical imaging

The Quasar Feedback Survey: characterizing CO excitation in quasar host galaxies

\ua9 2023 The Author(s). Published by Oxford University Press on behalf of Royal Astronomical Society.We present a comprehensive study of the molecular gas properties of 17 Type 2 quasars at z &lt; 0.2 from the Quasar Feedback Survey (L &gt; 1042.1), selected by their high [O iii] luminosities and displaying a large diversity of radio jet properties, but dominated by LIRG-like galaxies. With these data, we are able to investigate the impact of AGN and AGN feedback mechanisms on the global molecular interstellar medium. Using Atacama Pathfinder EXperiment and ALMA ACA observations, we measure the total molecular gas content using the CO(1-0) emission and homogeneously sample the carbon monoxide (CO) spectral line energy distributions, observing CO transitions (Jup = 1, 2, 3, 6, 7). We observe high r21 ratios (r21 = L\u27CO(2-1)/L\u27CO(1-0)) with a median r21 = 1.06, similar to local (U)LIRGs (with r21 ∼1) and higher than normal star-forming galaxies (with r21 ∼0.65). Despite the high r21 values, for the seven targets with the required data, we find low excitation in CO(6-5) &amp; CO(7-6) (r61 and r62 &lt; 0.6 in all but one target), unlike high-redshift quasars in the literature, which are far more luminous and show higher line ratios. The ionized gas traced by [O iii] exhibits systematically higher velocities than the molecular gas traced by CO. We conclude that any effects of quasar feedback (e.g. via outflows and radio jets) do not have a significant instantaneous impact on the global molecular gas content and excitation and we suggest that it only occurs on more localized scales

Quasar Feedback Survey: molecular gas affected by central outflows and by ~10 kpc radio lobes reveal dual feedback effects in `radio quiet' quasars

We present a study of molecular gas, traced via CO (3-2) from ALMA data, of four z< 0.2, `radio quiet', type 2 quasars (log [L(bol)/(erg/s)] = 45.3 - 46.2; log [L(1.4 GHz)/(W/Hz)] = 23.7 - 24.3). Targets were selected to have extended radio lobes (>= 10 kpc), and compact, moderate-power jets (1 - 10 kpc; log [Pjet/(erg/s)]= 43.2 - 43.7). All targets show evidence of central molecular outflows, or injected turbulence, within the gas disks (traced via high-velocity wing components in CO emission-line profiles). The inferred velocities (Vout = 250 - 440 km/s) and spatial scales (0.6 - 1.6 kpc), are consistent with those of other samples of luminous low-redshift AGN. In two targets, we observe extended molecular gas structures beyond the central disks, containing 9 - 53 % of the total molecular gas mass. These structures tend to be elongated, extending from the core, and wrap-around (or along) the radio lobes. Their properties are similar to the molecular gas filaments observed around radio lobes of, mostly `radio loud', Brightest Cluster Galaxies. They have: projected distances of 5 - 13 kpc; bulk velocities of 100 - 340 km/s; velocity dispersion of 30 - 130 km/s; inferred mass outflow rates of 4 - 20 Msolar/yr; and estimated kinetic powers of log [Ekin/(erg/s)]= 40.3 - 41.7. Our observations are consistent with simulations that suggest moderate-power jets can have a direct (but modest) impact on molecular gas on small scales, through direct jet-cloud interactions. Then, on larger scales, jet-cocoons can push gas aside. Both processes could contribute to the long-term regulation of star formation.Comment: Accepted for publication in MNRAS; references updated; typos correcte

The Quasar Feedback Survey: characterising CO excitation in quasar host galaxies

We present a comprehensive study of the molecular gas properties of 17 Type 2 quasars at $z$10^{42.1}$$\rm ergs^{-1}$), selected by their high [OIII] luminosities and displaying a large diversity of radio jet properties, but dominated by LIRG-like galaxies. With these data, we are able to investigate the impact of AGN and AGN feedback mechanisms on the global molecular interstellar medium. Using APEX and ALMA ACA observations, we measure the total molecular gas content using the CO(1-0) emission and homogeneously sample the CO spectral line energy distributions (SLEDs), observing CO transitions (J$_{up}$= 1, 2, 3, 6, 7). We observe high$r_{21}$ratios (r$_{21}$= L'$_{CO(2-1)}$/L'$_{CO(1-0)}$) with a median$r_{21}$= 1.06, similar to local (U)LIRGs (with$r_{21}$$\sim$1) and higher than normal star-forming galaxies (with r$_{21}$$\sim$0.65). Despite the high$r_{21} values, for the 7 targets with the required data we find low excitation in CO(6-5) & CO(7-6) (r_{61}$and$r_{62}$ < 0.6 in all but one target), unlike high redshift quasars in the literature, which are far more luminous and show higher line ratios. The ionised gas traced by [OIII] exhibit systematically higher velocities than the molecular gas traced by CO. We conclude that any effects of quasar feedback (e.g. via outflows and radio jets) do not have a significant instantaneous impact on the global molecular gas content and excitation and we suggest that it only occurs on more localised scales.Comment: 32 pages (20 in the main body of the paper and 12 in the appendix), 28 figures (10 in main body of paper and 18 in appendix) Accepted for publication in MNRAS. Data available at https://doi.org/10.25405/data.ncl.2431250

Heat Stress and Goat Welfare: Adaptation and Production Considerations

This review attempted to collate and synthesize information on goat welfare and production constraints during heat stress exposure. Among the farm animals, goats arguably are considered the best-suited animals to survive in tropical climates. Heat stress was found to negatively influence growth, milk and meat production and compromised the immune response, thereby significantly reducing goats’ welfare under extensive conditions and transportation. Although considered extremely adapted to tropical climates, their production can be compromised to cope with heat stress. Therefore, information on goat adaptation and production performance during heat exposure could help assess their welfare. Such information would be valuable as the farming communities are often struggling in their efforts to assess animal welfare, especially in tropical regions. Broadly three aspects must be considered to ensure appropriate welfare in goats, and these include (i) housing and environment; (ii) breeding and genetics and (iii) handling and transport. Apart from these, there are a few other negative welfare factors in goat rearing, which differ across the production system being followed. Such negative practices are predominant in extensive systems and include nutritional stress, limited supply of good quality water, climatic extremes, parasitic infestation and lameness, culminating in low production, reproduction and high mortality rates. Broadly two types of methodologies are available to assess welfare in goats in these systems: (i) animal-based measures include behavioral measurements, health and production records and disease symptoms; (ii) resources based and management-based measures include stocking density, manpower, housing conditions and health plans. Goat welfare could be assessed based on several indicators covering behavioral, physical, physiological and productive responses. The important indicators of goat welfare include agonistic behavior, vocalization, skin temperature, body condition score (BCS), hair coat conditions, rectal temperature, respiration rate, heart rate, sweating, reduced growth, reduced milk production and reduced reproductive efficiency. There are also different approaches available by which the welfare of goats could be assessed, such as naturalistic, functional and subjective approaches. Thus, assessing welfare in goats at every production stage is a prerequisite for ensuring appropriate production in this all-important species to guarantee optimum returns to the marginal and subsistence farmers

The Quasar feedback survey: characterizing CO excitation in quasar host galaxies

We present a comprehensive study ofthemolecular gas properties of 17Type 2 quasars at z <0.2 fromthe Quasar Feedback Survey (L[O III] > 1042.1 ergs−1), selected by their high [O III] luminosities and displaying a large diversity of radio jet properties, but dominated by LIRG-like galaxies. With these data, we are able to investigate the impact of AGN and AGN feedback mechanisms on the global molecular interstellar medium. Using Atacama Pathfinder EXperiment and ALMA ACA observations, we measure the total molecular gas content using the CO(1-0) emission and homogeneously sample the carbon monoxide (CO) spectral line energy distributions, observing CO transitions (Jup = 1, 2, 3, 6, 7). We observe high r21 ratios (r21 = L’CO(2-1)/L’CO(1-0)) with a median r21 = 1.06, similar to local (U)LIRGs (with r21 ∼ 1) and higher than normal star-forming galaxies (with r21 ∼ 0.65). Despite the high r21 values, for the seven targets with the required data, we find low excitation in CO(6-5) & CO(7-6) (r61 and r62 < 0.6 in all but one target), unlike high-redshift quasars in the literature, which are far more luminous and show higher line ratios. The ionized gas traced by [O III] exhibits systematically higher velocities than the molecular gas traced by CO. We conclude that any effects of quasar feedback (e.g. via outflows and radio jets) do not have a significant instantaneous impact on the global molecular gas content and excitation and we suggest that it only occurs on more localized scales

Network-Based Elucidation of Human Disease Similarities Reveals Common Functional Modules Enriched for Pluripotent Drug Targets

Current work in elucidating relationships between diseases has largely been based on pre-existing knowledge of disease genes. Consequently, these studies are limited in their discovery of new and unknown disease relationships. We present the first quantitative framework to compare and contrast diseases by an integrated analysis of disease-related mRNA expression data and the human protein interaction network. We identified 4,620 functional modules in the human protein network and provided a quantitative metric to record their responses in 54 diseases leading to 138 significant similarities between diseases. Fourteen of the significant disease correlations also shared common drugs, supporting the hypothesis that similar diseases can be treated by the same drugs, allowing us to make predictions for new uses of existing drugs. Finally, we also identified 59 modules that were dysregulated in at least half of the diseases, representing a common disease-state “signature”. These modules were significantly enriched for genes that are known to be drug targets. Interestingly, drugs known to target these genes/proteins are already known to treat significantly more diseases than drugs targeting other genes/proteins, highlighting the importance of these core modules as prime therapeutic opportunities