173 research outputs found

    Incidence of anthelmintic resistance in cattle farms in Northern Germany – first results

    Get PDF
    Anthelmintic resistance (AR) is an increasing problem worldwide especially for small ruminants and it is also rising in cattle. To maintain the efficacy of anthelmintics is an important objective. The current project aims at the investigation of the current efficacy of macrocyclic lactone anthelmintics for strongylid nematodes in first season grazing (FSG) calves in Northern Germany. On 8 participating farms in Northern Germany faecal egg count reduction tests (FECRT) with ivermectin (IVM) were performed. On 3 farms the efficacy of IVM was found to be ≤90% and on only 4 farms it was > 95% at 14 days post treatment (d.p.t.). Only 2 farms showed a reduction ≥ 95% at 21 d.p.t.. This survey reveals a rising problem of AR. The problem of drug resistance places the welfare of animals at risk. In organic farming, without a preventive treatment, livestock may harbour high worm counts. Therefore it is necessary to maintain powerful anthelmintic drugs to guarantee the welfare of animals that need salvage treatment. To investigate the AR problem in cattle more surveys with different anthelmintic drug classes are urgently needed

    Investigation on the influence of nematophagous fungi as feed additive on nematode infection risk of sheep and goats on pasture

    Get PDF
    Gastrointestinal nematodes in small ruminants cause high economic losses. Thus on most farms anthelmintic treatment is required. In response to increasing problems with anthelmintic resistance, biological control, for example the use of nematophagous fungi, has received significant attention. The aim of this study was to investigate the effect of Duddingtonia flagrans orally applied to small ruminants on natural infection with gastrointestinal nematodes in a field study in Northern Germany. 20 goats and 20 sheep were fed daily for 3 months with 5x105 spores of D. flagrans per kg bodyweight. Differences in body weight, faecal egg count and larval development in faeces and on pasture in comparison with same-sized control groups were analysed. After 3 months the control goats showed significantly higher mean faecal egg count than the fungus-fed group. No significant difference was found between the two sheep groups. The maximum in larval reduction in faeces was 81.3 % in the sheep groups and 67.9 % in the goat groups (not significant). At the end of the study the body weight gain in the fungus-treated groups was 1.7 kg higher in goats and 0.7 kg higher in sheep than in the control groups (not significant). Regarding the first-year-grazing goats only, the bodyweights revealed significant differences (p<0.05). No statistically significant differences were observed in pasture larval counts. In the study presented here, no clear effect of fungus could be observed. A modified feeding regimen, perhaps with permanent release boluses or feed blocks, may improve the efficacy. Furthermore, it seems that climatic conditions during the study period could have influenced the results and displayed how sensitive the fungus application may be on such parameters

    Untersuchungen zur Wirksamkeit von Anthelminthika bei erstsömmrigen Rindern in Europa

    Get PDF
    Resistance to anthelmintics is a threat to several animal industries world wide. Nevertheless, the use of effective anthelmintics to control nematode infections in cattle still remains irreplaceable. Anthelmintic resistance in cattle has been reported in New Zealand, North and South America and England but so far not in Europe. To be able to determine the extent of anthelmintic resistance in nematodes of farm animals and to monitor the success of any resistance management requires reliable tests for the detection of anthelmintic resistance. One of the objectives of PARASOL, a European Framework 6 funded project, is to produce standard operating procedures for the running of a faecal egg count reduction test (FECRT). Standardized procedures for the FECRT have been developed and surveys with injectable ivermectin were then performed in Germany, Sweden and Belgium in 2006 and 2007. Additional tests using benzimidazoles were performed in Sweden and Germany in 2007. Furthermore, some of the refractory strains will be isolated to test whether the phenomena observed in the field was due to the evolution of anthelmintic resistance

    The mitochondrial genome of Parascaris univalens - implications for a “forgotten” parasite

    Get PDF
    © Jabbar et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. The file attached is the Published/publisher’s pdf version of the article

    Comparative analysis of intestinal helminth infections in colic and non-colic control equine patients

    Get PDF
    All around the world, intestinal helminths constitute one of the most prevalent life-long occurring infections and re-infections affecting all horse age groups. A range of parasite species among strongyles, ascarids, and tapeworms is known to have the potential to cause colic in horses. However, there is a lack of current scientific evidence on the actual relevance of helminth infection levels in the context of colic in horses kept during prevailing epidemiological conditions. Thus, a prospective case-control study on the occurrence of intestinal helminths in a total of 620 mainly adult equine clinic patients was conducted to investigate the association between colic and helminth infection. For each horse, a range of copromicroscopic, serological, and clinical data was obtained, in addition to a questionnaire on relevant anamnestic data, including previous anthelmintic treatment and husbandry. Using a FLOTAC-based copromicroscopic diagnosis, the highest infection rates were seen for strongyles (41.8%), followed by Anoplocephala perfoliata and Parascaris spp. (both 0.8%), with no significant difference between the two study groups. Employing a real-time PCR a 1.1% S. vulgaris DNA prevalence was found. Considerably higher seroprevalences were observed using S. vulgaris and A. perfoliata ELISAs, with 32.3% and 10.7%, respectively. It was noteworthy that no association concerning either serologic status was encountered with colic status. The shedding of strongyle eggs was associated with a 1.8-times increased risk of S. vulgaris seropositivity. Recent anthelmintic treatment was associated with the onset of colic, as animals who had received an anthelmintic during the previous week had a 2.4-times higher risk of signs of colic compared to those who had been treated at least eight weeks prior. Another noteworthy observation was that ponies were significantly less often affected by colic than warmbloods. The high S. vulgaris and considerable A. perfoliata seroprevalences encountered in this investigation should prompt veterinarians, farm managers, and horse owners to maintain consequent and effective worm control measures
    • …
    corecore