Internet of Things and the Future Scope in Libraries

IoT is a unique technology that gained its momentum in recent years. Though the technologyacquires its potential libraries like organizations are in a stage of infancy to adopt the IoT technology. IoT is established in any organization with the help of interconnected identifiable embedded computing devices within the existing infrastructure. So that the use of technology allows us a greater chance for achieving a prosperous library management system with maximum efficiency at least effort. Automation of Library services is suitable approach where various devices can be managed at a single place by implementing Internet of Things. The idea behind the IoT and its future scope in libraries is to provide an user friendly approach towards libraries and at the same time ensuring a systematic library services so as to properly utilize the time and energy of employees

Exploring the Awareness of Information Search Techniques Gained from Various Sources: A Study Among the Research Scholars of University of Kerala

An exploratory approach of study is made to understand the extent and level of awareness of search techniques which is carried out among the research scholars of departments in University of Kerala. The preferred source of developing awareness in information search and access by the researchers need to identified for the quickly approach of the right documents for their research works. It is found to be very essential to conduct a study that is relevant in the present digital environment which results in the benefit of the researchers for suitably selecting the search techniques required for their topic. The study is conducted among the research scholars including both M.Phil. and Ph.D. of the ten faculties. The paper explores the level and extent of various sources where they gained awareness of search techniques. The stratified random sampling method is adopted here to collect the required data through questionnaire. The paper evidently collected data from the population of 830, where a sample of 656 Research Scholars of the ten faculties was selected for the study. The Mann-Whitney U test is applied to analyse the data set and the calculated statistical evidences did not support the formulated null hypothesis. The observed Mann-Whitney U test values are; Help Menu (U=44258.500), Online Tutorials (U=45249.000), Guidelines (U=46079.000), Class Room Trainings (U=46484.000), and Library User Programs (U=43946.000). Study enabled the authors to find an answer for the research question- Is there any significant differences between the Mean value of Gender and usage levels of sources

Hubungan Antara Gangguan Tidur Dengan Pertumbuhan Pada Anak Usia 3-6 Tahun Di Kota Semarang

Latar Belakang :Prevalensi gangguan pertumbuhan masih cukup besar. Salah satu faktor yang dapat mempengaruhi pertumbuhan adalah faktor kelainan hormonal yang bisa dikarenakan oleh gangguan tidur. Sekitar 75% hormon pertumbuhan disintesis pada saat anak tidur, sehingga bila terjadi gangguan tidur pada anak maka hormon pertumbuhan akan terganggu. Tujuan : Menguji hubungan antara gangguan tidur dengan pertumbuhan pada anak usia 3-6 tahun di Kota Semarang.Metode : Penelitian observasional analitik dengan desain cross-sectional dilakukan pada periode Maret – Juni 2013.Subjek penelitian adalah orangtua anak yang memiliki anak berusia 3-6 tahun di beberapa TK/TPA dan PAUD di Kota Semarang. Pengambilan data dilakukan dengan metode wawancara dengan menggunakan kuesioner SDSC serta pengukuran antropometri meliputi berat badan, tinggi badan, dan lingkar kepala pada anak. Uji statistik menggunakan uji Mann-Whitney.Hasil :Jumlah responden sebanyak 183 anak, terdiri atas 146 anak mengalami gangguan tidur. Dari hasil analisis didapatkan perbedaan bermakna pada rerata skor HAZ antara kelompok gangguan tidur dan tidak gangguan tidur(p=0,036). Tidak terdapat perbedaan bermakna antara kedua kelompok pada rerata skor WAZ (p=0,244), Z-score IMT terhadap umur (p=0,855), dan Z-score lingkar kepala terhadap umur (p=0,389). Karakteristik data antara kedua kelompok menunjukkan perbedaanbermakna pada variabel usia, pendidikan terakhir ayah, dan status sosial ekonomi.Kesimpulan :Gangguan tidur pada anak berhubungan secara signifikan terhadap tinggi badan pada anak, namun tidak berhubungan secara signifikan pada berat badan, IMT, dan lingkar kepala pada anak

Incidence of organophosphate and carbamate poisoning in dogs within Maiduguri, North-eastern Nigeria

The persistent application of chemicals in pest control and agricultural processes possess a public health concern as their use are often associated with acute or chronic poisoning cases in both humans and animals. In veterinary medicine, pesticides such as organophosphates and carbamates are exclusively used in ectoparasitic control through pour on, tick bath and fumigation. The incidence of organophosphate or carbamate poisoning in dogs within Maiduguri, north-eastern Nigeria was assessed using three government approved and licensed veterinary centres. Data were obtained through the review of three years (2016-2018) retrospective cases of organophosphate/carbamate poisoning and administration of questionnaires to actively practising veterinarians. Investigation revealed that organophosphate/carbamate poisoning in dogs within Maiduguri metropolis constituted 37% of poisoning cases and was on the increase in recent years with 22.96% of the total cases reported in 2016, 34.08% in 2017 and 42.96% in 2018. The case was most prevalent at the peak of the rainy season around July and August. The common clinical signs observed include salivation, vomiting, diarrhoea, muscle spasms, severe weakness and paralysis. Management was usually supportive and symptomatic while antidotal therapy revolved on atropine sulphate only. The effect of ageing in organophosphate poisoning was neglected by most of the clinicians as more than 50% would administer atropine sulphate without considering the duration of the onset of poisoning. It was concluded that the incidence of organophosphate and carbamate poisoning in dogs in Maiduguri constituted 37% of all poisoning cases where 22.96% and 42.96% of it were reported in 2016 and 2018, respectively. Enlightenment programmes for the public and professionals are recommended on the increased cases of poisoning and proper use of antidote in the treatment of chemical toxicosis

Transportation research needs and issues for Chinese agriculture

Interprovincial circulation of grain and wholesale markets in China / Wu Shuo -- Inter-state/province grain transportation in the U.S. and China / Tenpao Lee, Robert J. Hauser, Stanley R. Thompson, and Barbara J. Hrutka -- Methodology and data systems for study of transportation / Won W. Koo and Jerry Fruin -- An application of a spatial equilibrium model to analyze the impact on China's trade of a policy change / Shwu-Eng H. Webb, Catherine K. Halbrendt, Rajaram Gana, and Francis Tuan -- Possible Joint Chinese and U.S. grain transportation and distribution research opportunities / Roland R. Robinson and Donald W. Larson -- Transportation research needs and issues for Chinese agriculture: discussion of session presentations / Dale G. Anderso

SUFU haploinsufficiency causes a recognisable neurodevelopmental phenotype at the mild end of the Joubert syndrome spectrum.

Joubert syndrome (JS) is a recessively inherited ciliopathy characterised by congenital ocular motor apraxia (COMA), developmental delay (DD), intellectual disability, ataxia, multiorgan involvement, and a unique cerebellar and brainstem malformation. Over 40 JS-associated genes are known with a diagnostic yield of 60%-75%.In 2018, we reported homozygous hypomorphic missense variants of the SUFU gene in two families with mild JS. Recently, heterozygous truncating SUFU variants were identified in families with dominantly inherited COMA, occasionally associated with mild DD and subtle cerebellar anomalies. We reanalysed next generation sequencing (NGS) data in two cohorts comprising 1097 probands referred for genetic testing of JS genes. Heterozygous truncating and splice-site SUFU variants were detected in 22 patients from 17 families (1.5%) with strong male prevalence (86%), and in 8 asymptomatic parents. Patients presented with COMA, hypotonia, ataxia and mild DD, and only a third manifested intellectual disability of variable severity. Brain MRI showed consistent findings characterised by vermis hypoplasia, superior cerebellar dysplasia and subtle-to-mild abnormalities of the superior cerebellar peduncles. The same pattern was observed in two out of three tested asymptomatic parents. Heterozygous truncating or splice-site SUFU variants cause a novel neurodevelopmental syndrome encompassing COMA and mild JS, which likely represent overlapping entities. Variants can arise de novo or be inherited from a healthy parent, representing the first cause of JS with dominant inheritance and reduced penetrance. Awareness of this condition will increase the diagnostic yield of JS genetic testing, and allow appropriate counselling about prognosis, medical monitoring and recurrence risk

19q13.11 cryptic deletion : description of two new cases and indication for a role of WTIP haploinsufficiency in hypospadias

Developmental delay/intellectual disabilities, speech disturbance, pre- and postnatal growth retardation, microcephaly, signs of ectodermal dysplasia, and genital malformations in males (hypospadias) represent the phenotypic core of the recent emerging 19q13.11 deletion syndrome. Using array-CGH for genome-wide screening we detected an interstitial deletion of chromosome band 19q13.11 in two patients exhibiting the recognizable pattern of malformations as described in other instances of this submicroscopic genomic imbalance. The deletion detected in our patients has been compared with previously reported cases leading to the refinement of the minimal overlapping region (MOR) for this microdeletion syndrome to 324 kb. This region encompasses five genes: four zinc finger (ZNF) genes belonging to the KRAB-ZNF subfamily (ZNF302, ZNF181, ZNF599, and ZNF30) and LOC400685. On the basis of our male patient 1 and on further six male cases of the literature, we also highlighted that larger 19q13.11 deletions including the Wilms tumor interacting protein (WTIP) gene, proximal to the MOR, results in hypospadias making this gene a possible candidate for this genital abnormality due to its well-known interaction with WT1. Although the mechanism underlying the phenotypic effects of copy number alterations involving KRAB-ZNF genes at 19q13.11 has not clearly been established, we suggest their haploinsufficiency as the most likely candidate for the phenotypic core of the 19q13.11 deletion syndrome. In addition, we hypothesized WTIP gene haploinsufficiency as responsible for hypospadias