Ocean feature models ? their use and effectiveness in ocean acoustic forecasting

International audienceThe aim of this paper is to test the effectiveness of feature models in ocean acoustic forecasting. Feature models are simple mathematical representations of the horizontal and vertical structures of ocean features (such as fronts and eddies), and have been used primarily for assimilating new observations into forecasts and for compressing data. In this paper we describe the results of experiments in which the models have been tested in acoustic terms in eddy and frontal environments in the Iceland Faeroes region. Propagation-loss values were obtained with a 2D parabolic-equation (PE) model, for the observed fields, and compared to PE results from the corresponding feature models and horizontally uniform (range-independent) fields. The feature models were found to represent the smoothed observed propagation-loss field to within an rms error of 5 dB for the eddy and 7 dB for the front, compared to 10?15-dB rms errors obtained with the range-independent field. Some of the errors in the feature-model propagation loss were found to be due to high-amplitude 'oceanographic noise' in the field. The main conclusion is that the feature models represent the main acoustic properties of the ocean but do not show the significant effects of small-scale internal waves and fine-structure. It is recommended that feature models be used in conjunction with stochastic models of the internal waves, to represent the complete environmental variability

Coherency-maximizing exploration in the supermarket

In uncertain environments, effective decision makers balance exploiting options that are currently preferred against exploring alternative options that may prove superior. For example, a honeybee foraging for nectar must decide whether to continue exploiting the current patch or move to a new location. When the relative reward of options changes over time, humans explore in a normatively correct fashion, exploring more often when they are uncertain about the relative value of competing options. However, rewards in these laboratory studies were objective (for example, monetary payoff), whereas many real-world decision environments involve subjective evaluations of reward (for example, satisfaction with food choice). In such cases, rather than choices following preferences, preferences may follow choices with subjective reward (that is, value) to maximize coherency between preferences and behaviour 12,13 . If so, increasing coherency would lessen the tendency to explore while uncertainty increases, contrary to previous findings. To evaluate this possibility, we examined the exploratory choices of more than 280,000 anonymized individuals in supermarkets over several years. Consumers’ patterns of exploratory choice ran counter to normative models for objective rewards — the longer the exploitation streak for a product, the less likely people were to explore an alternative. Furthermore, customers preferred coupons to explore alternative products when they had recently started an exploitation streak. These findings suggest interventions to promote healthy lifestyle choices

GIS Tools for 3-D Surficial Mapping in Ohio

This poster was presented at the 2007 meeting of the Digital Mapping Techniques Conference in Columbia, South Carolina, May 20-23, 2007.The Ohio Department of Natural Resources, Division of Geological Survey is currently mapping the surficial geology of Ohio in three dimensions (3-D) using a modified version of the stack-mapping technique of Kempton (1981). The stack-mapping technique depicts the geology for an area in 3-D by listing the unconsolidated (mostly glacial) geologic units from the surface to bedrock, the thickness of each unit, and the underlying bedrock unit. The new mapping of the surficial geology is intended to replace the older and smaller-scale mapping that was based upon generalized, two-dimensional mapping techniques. Three ArcMap-based software applications were developed to assist with the stack-unit mapping program. The first software application used the lithologies from water wells to create on-screen graphics representing the stratigraphic columns for each well record. These stratigraphic columns are interpreted by the geologist to assign a generalized stack unit for each polygon. The second software application consists of two tools used to attribute and label the stack-map polygons, which will capture the information in the GIS and for cartographic display. The first tool attributes a one-to-many relationship between a surficial-geology polygon and the lithology table. The second tool labels the surficial-geology polygons with the stack text for use in map publishing. The third application performs custom queries against the lithology table that can be used to create derivative mapping products, such as location and thickness of sand and gravel resources. These three applications allow the efficient creation of 3-D surficial-geology polygons and labels within a GIS database, and provide analysis tool to facilitate the use of the 3-D surficial geology maps for specific applications.Great Lakes Geologic Mapping Coalition, U.S. Geological Surve

Physical activity and health related quality of life

Copyright @ 2012 Anokye et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.This article has been made available through the Brunel Open Access Publishing Fund.BACKGROUND: Research on the relationship between Health Related Quality of Life (HRQoL) and physical activity (PA), to date, have rarely investigated how this relationship differ across objective and subjective measures of PA. The aim of this paper is to explore the relationship between HRQoL and PA, and examine how this relationship differs across objective and subjective measures of PA, within the context of a large representative national survey from England. METHODS: Using a sample of 5,537 adults (40–60 years) from a representative national survey in England (Health Survey for England 2008), Tobit regressions with upper censoring was employed to model the association between HRQoL and objective, and subjective measures of PA controlling for potential confounders. We tested the robustness of this relationship across specific types of PA. HRQoL was assessed using the summary measure of health state utility value derived from the EuroQol-5 Dimensions (EQ-5D) whilst PA was assessed via subjective measure (questionnaire) and objective measure (accelerometer- actigraph model GT1M). The actigraph was worn (at the waist) for 7 days (during waking hours) by a randomly selected sub-sample of the HSE 2008 respondents (4,507 adults – 16 plus years), with a valid day constituting 10 hours. Analysis was conducted in 2010. RESULTS: Findings suggest that higher levels of PA are associated with better HRQoL (regression coefficient: 0.026 to 0.072). This relationship is consistent across different measures and types of PA although differences in the magnitude of HRQoL benefit associated with objective and subjective (regression coefficient: 0.047) measures of PA are noticeable, with the former measure being associated with a relatively better HRQoL (regression coefficient: 0.072). CONCLUSION: Higher levels of PA are associated with better HRQoL. Using an objective measure of PA compared with subjective shows a relatively better HRQoL.This project was funded by the NIHR Health Technology Assessment programme (project number 08/72/01)

Torpor in marsupials: Recent advances

We report new findings about torpor in marsupials with regard to three energy demanding processes: (i) development and growth, (ii) reproduction, and (iii) rewarming. Young marsupials use torpor extensively after they develop endothermy, and torpor is generally deeper and longer than in the same individuals when they reach adult size. Adult marsupials also employ torpor during pregnancy and/or lactation to reduce energy expenditure and perhaps to store fat for later use. Moreover, to enhance the energy-conserving potential of torpor, desert marsupials bask during arousal to minimize energy costs of rewarming. We show that the functions of torpor extend beyond merely reducing energy expenditure during food shortages and that torpor can save substantial amounts of energy even during the rewarming process

Promoting and maintaining physical activity in the transition to retirement: a systematic review of interventions for adults around retirement age

It has been argued that transition points in life, such as the approach towards, and early years of retirement present key opportunities for interventions to improve the health of the population. Research has also highlighted inequalities in health status in the retired population and in response to interventions which should be addressed. We aimed to conduct a systematic review to synthesise international evidence on the types and effectiveness of interventions to increase physical activity among people around the time of retirement. A systematic review of literature was carried out between February 2014 and April 2015. Searches were not limited by language or location, but were restricted by date to studies published from 1990 onwards. Methods for identification of relevant studies included electronic database searching, reference list checking, and citation searching. Systematic search of the literature identified 104 papers which described study populations as being older adults. However, we found only one paper which specifically referred to their participants as being around the time of retirement. The intervention approaches for older adults encompassed: training of health care professionals; counselling and advice giving; group sessions; individual training sessions; in-home exercise programmes; in-home computer-delivered programmes; in-home telephone support; in-home diet and exercise programmes; and community-wide initiatives. The majority of papers reported some intervention effect, with evidence of positive outcomes for all types of programmes. A wide range of different measures were used to evaluate effectiveness, many were self-reported and few studies included evaluation of sedentary time. While the retirement transition is considered a significant point of life change, little research has been conducted to assess whether physical activity interventions at this time may be effective in promoting or maintaining activity, or reducing health inequalities. We were unable to find any evidence that the transition to retirement period was, or was not a significant point for intervention. Studies in older adults more generally indicated that a range of interventions might be effective for people around retirement age

'It gives me my freedom’: technology and responding to bodily limitations in Motor Neuron Disease

People living with Motor Neuron Disease (MND) experience profound and rapidly progressing impairment. In order to maintain their physical and social functioning, people so affected employ a range of technologies and technological aids (body auxiliaries) to enhance their life and maintain wellbeing. Using a phenomenological study design, we explored the experiences of 42 men and women who had been diagnosed with MND. Although many participants initially resisted the adoption of aids (often-electronic devices that enabled continued participation in daily life) or tools (the instruments that allowed achievement of specific tasks), such technologies offered a way for people with MND to overcome, to some extent, the limitations posed by their physical degeneration. Through generating a sense of ‘normality’, these kinds of ‘enabling’ technologies promoted social engagement and the maintenance of valued relationships or activities. Technologies can provide people with MND with some positive experiences within a way of being-in-the-world that has become so difficult and challenging

The specificity and patterns of staining in human cells and tissues of p16INK4a antibodies demonstrate variant antigen binding

The validity of the identification and classification of human cancer using antibodies to detect biomarker proteins depends upon antibody specificity. Antibodies that bind to the tumour-suppressor protein p16INK4a are widely used for cancer diagnosis and research. In this study we examined the specificity of four commercially available anti-p16INK4a antibodies in four immunological applications. The antibodies H-156 and JC8 detected the same 16 kDa protein in western blot and immunoprecipitation tests, whereas the antibody F-12 did not detect any protein in western blot analysis or capture a protein that could be recognised by the H-156 antibody. In immunocytochemistry tests, the antibodies JC8 and H-156 detected a predominately cytoplasmic localised antigen, whose signal was depleted in p16INK4a siRNA experiments. F-12, in contrast, detected a predominately nuclear located antigen and there was no noticeable reduction in this signal after siRNA knockdown. Furthermore in immunohistochemistry tests, F-12 generated a different pattern of staining compared to the JC8 and E6H4 antibodies. These results demonstrate that three out of four commercially available p16INK4a antibodies are specific to, and indicate a mainly cytoplasmic localisation for, the p16INK4a protein. The F-12 antibody, which has been widely used in previous studies, gave different results to the other antibodies and did not demonstrate specificity to human p16INK4a. This work emphasizes the importance of the validation of commercial antibodies, aside to the previously reported use, for the full verification of immunoreaction specificity