304 research outputs found

    Effect of polymer coatings on fatigue strength of aluminum alloy 2024 box beams

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    Previous investigators have shown that polymer coatings raise the fatigue strength of metals tested in air to about the same level as that of uncoated specimens tested in vacuum. The results are given of tests to determine if a polymer coating would improve the fatigue strength of built-up aluminum alloy members simulating aircraft construction. Aluminum alloy 2024-T4 riveted box beams were subjected to constant amplitude fatigue tests in air as well as in salt water fog. The coating did not improve the fatigue strength of beams tested in either environment. This is believed to result from the fact that most failures originated at rivet holes, which were isolated from both the coating and the environment

    Static deformation of heavy spring due to gravity and centrifugal force

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    The static equilibrium deformation of a heavy spring due to its own weight is calculated for two cases. First for a spring hanging in a constant gravitational field, then for a spring which is at rest in a rotating system where it is stretched by the centrifugal force. Two different models are considered. First a discrete model assuming a finite number of point masses connected by springs of negligible weight. Then the continuum limit of this model. In the second case the differential equation for the deformation is obtained by demanding that the potential energy is minimized. In this way a simple application of the variational calculus is obtained.Comment: 11 pages, 2 figure

    Multilayer Corrosion of Aluminum Activated by Lead

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    Segregation of Pb as a nanofilm between the thermal oxide and the metal substrate as a result of high temperature heat-treatment is known to activate aluminum alloys anodically in chloride solution. The relationship between the oxidation peaks in the polarization curve and corrosion morphology was investigated by the use of a video technique during electrochemical polarization. A model binary Al–Pb alloy containing 20 ppm Pb, which was annealed at 600°C, showed two oxidation peaks at −0.95 and −0.88 V_SCE. The video measurements revealed superficial etching of the surface by selective oxidation of the aluminum metal twice, followed each time by repassivation, as the two oxidation peaks were resolved during anodic potentiodynamic sweep. Ex situ scanning and transmission electron microscopy of the corroded specimens indicated that the first layer of etching followed the Pb film and undermined the thermal oxide, which remained attached to the metal surface at discrete locations, thereby forming a crevice. The second layer of attack was caused by crevice corrosion of the aluminum substrate in the crevice formed by the preceding oxidation process, which resulted in the removal of the attached thermal oxide film. The exposed aluminum substrate started to pit as the pitting potential was finally exceeded

    Development of lower limb range of motion from early childhood to adolescence in cerebral palsy: a population-based study

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    <p>Abstract</p> <p>Background</p> <p>The decreasing range of joint motion caused by insufficient muscle length is a common problem in children with cerebral palsy (CP), often worsening with age. In 1994 a CP register and health care programme for children with CP was initiated in southern Sweden. The aim of this study was to analyse the development of the passive range of motion (ROM) in the lower limbs during all the growth periods in relation to gross motor function and CP subtype in the total population of children with CP.</p> <p>Methods</p> <p>In total, 359 children with CP born during 1990-1999, living in the southernmost part of Sweden in the year during which they reached their third birthday and still living in the area in the year of their seventh birthday were analysed. The programme includes a continuous standardized follow-up with goniometric measurements of ROM in the lower limbs. The assessments are made by each child's local physiotherapist twice a year until 6 years of age, then once a year. In total, 5075 assessments from the CPUP database from 1994 to 1 January 2007 were analysed.</p> <p>Results</p> <p>The study showed a decreasing mean range of motion over the period 2-14 years of age in all joints or muscles measured. The development of ROM varied according to GMFCS level and CP subtype.</p> <p>Conclusion</p> <p>We found a decreasing ROM in children with CP from 2-14 years of age. This information is important for both the treatment and follow-up planning of the individual child as well as for the planning of health care programmes for all children with CP.</p

    Rotating strings

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    Analytical expressions are provided for the configurations of an inextensible, flexible, twistable inertial string rotating rigidly about a fixed axis. Solutions with trivial radial dependence are helices of arbitrary radius and pitch. Non-helical solutions are governed by a cubic equation whose roots delimit permissible values of the squared radial coordinate. Only curves coplanar with the axis of rotation make contact with it.Comment: added to discussion and made small revisions to tex

    Cerebral palsy in a total population of 4–11 year olds in southern Sweden. Prevalence and distribution according to different CP classification systems

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    <p>Abstract</p> <p>Background</p> <p>The aim of this study was to investigate the prevalence of cerebral palsy (CP) as well as to characterize the CP population, its participation in a secondary prevention programme (CPUP) and to validate the CPUP database.</p> <p>Methods</p> <p>The study population was born 1990–1997 and resident in Skåne/Blekinge on Jan 1<sup>st </sup>2002. Multiple sources were used. Irrespective of earlier diagnoses, neuropaediatrician and other professional medical records were evaluated for all children at the child habilitation units. The CPUP database and diagnosis registers at hospital departments were searched for children with CP or psychomotor retardation, whose records were then evaluated. To enhance early prevention, CP/probable CP was searched for also in children below four years of age born 1998–2001.</p> <p>Results</p> <p>The prevalence of CP was 2.4/1,000 (95% CI 2.1–2.6) in children 4–11 years of age born in Sweden, excluding post-neonatally acquired CP. Children born abroad had a higher prevalence of CP with more severe functional limitations. In the total population, the prevalence of CP was 2.7/1,000 (95% CI 2.4–3.0) and 48% were GMFCS-level I (the mildest limitation of gross motor function).</p> <p>One third of the children with CP, who were born or had moved into the area after a previous study in 1998, were not in the CPUP database. The subtype classification in the CPUP database was adjusted in the case of every fifth child aged 4–7 years not previously reviewed.</p> <p>Conclusion</p> <p>The prevalence of CP and the subtype distribution did not differ from that reported in other studies, although the proportion of mild CP tended to be higher.</p> <p>The availability of a second opinion about the classification of CP/CP subtypes is necessary in order to keep a CP register valid, as well as an active search for undiagnosed CP among children with other impairments.</p

    An experimental study of the impulse response of a vibro-impacting cantilever beam

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    The dynamics of a vibro-impacting cantilever beam experiment using an impact load cell is considered. The signal recorded from the cell produces spike train -type data. The issues related to the analysis of such data are discussed; particularly the sampling rate and threshold values. For vibro-impact motion of the beam, the duration of impacts is investigated by using a time of contact measure. The implications are discussed for vibro-impact systems mathematically modelled by using instantaneous impact assumptions (coefficient of restitution). Using the load cell to measure impact forces for the beam system is also considered. Then a delay reconstruction of the dynamics of the system by using interspike intervals is considered. It is demonstrated how this process is effected by the influence of noise and the data-acquision process using numerical simulations of the experimental data. It is shown how simple periodic motions can be identified by using a probability density approach and possible future research is highlighted

    Spasticity of the gastrosoleus muscle is related to the development of reduced passive dorsiflexion of the ankle in children with cerebral palsy: A registry analysis of 2,796 examinations in 355 children

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    Background and purpose Spasticity and muscle contracture are two common manifestations of cerebral palsy (CP). A spastic muscle may inhibit growth in length of the muscle, but the importance of this relationship is not known. In 1994, a register and a healthcare program for children with CP in southern Sweden were initiated. The child's muscle tone according to the Ashworth scale and the ankle range of motion (ROM) is measured annually during the entire growth period. We have used these data to analyze the relationship between spasticity and ROM of the gastrosoleus muscle. Patients and methods All measurements in the total population of children with CP aged 0-18 years during the period January 1995 through June 2008 were analyzed. The study was based on 2,796 examinations in 355 children. In the statistical analysis, the effect of muscle tone on ROM was estimated using a random effects model. Results The range of dorsiflexion of the ankle joint decreased in the total material by mean 19 (95% CI: 14-24) degrees during the first 18 years of life. There was a statistically significant association between the ROM and the child's level of spasticity during the year preceding the ROM measurement. Interpretation Spasticity is related to the development of muscle contracture. In the treatment of children with CP, the spasticity, contracture, and strength of the gastrosoleus muscle must be considered together

    Mutations in genes encoding complement inhibitors CD46 and CFH affect the age at nephritis onset in patients with systemic lupus erythematosus

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    INTRODUCTION: Inherited deficiencies of several complement components strongly predispose to systemic lupus erythematosus (SLE) while deficiencies of complement inhibitors are found in kidney diseases such as atypical hemolytic uremic syndrome (aHUS). METHODS: The exons of complement inhibitor genes: CD46 and CFH (factor H) were fully sequenced using Sanger method in SLE patients with nephritis originating from two cohorts from southern and mid Sweden (n = 196). All identified mutations and polymorphisms were then analyzed in SLE patients without nephritis (n = 326) and healthy controls (n = 523). RESULTS: We found non-synonymous, heterozygous mutations in CFH in 6.1% patients with nephritis in comparison to 4.0% and 5.4% in patients without nephritis and controls, respectively. No associations of SLE or nephritis with common variants in CFH (V62I/Y402H/E936D) were found. Furthermore, we found two non-synonymous heterozygous mutations in CD46 in SLE patients but not in controls. The A353V polymorphism, known to affect function of CD46, was found in 6.6% of nephritis patients vs 4.9% and 6.1% of the non-nephritis SLE patients and controls. The presence of mutations in CD46 and CFH did not predispose to SLE or nephritis but was associated with earlier onset of nephritis. Furthermore, we found weak indications that there is one protective and one risk haplotype predisposing to nephritis composed of several polymorphisms in non-coding regions of CD46, which were previously implicated in aHUS. CONCLUSION: SLE nephritis is not associated with frequent mutations in CFH and CD46 as found in aHUS but these may be modifying factors causing earlier onset of nephritis
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