9 research outputs found
Enhancement of crystallization with nucleotide ligands identified by dye-ligand affinity chromatography
- Author
- A Deniaud
- A Denizli
- A Denizli
- A Denizli
- A Denizli
- A Dong
- A McPherson
- AM Schnoes
- C-S Goh
- C-Y Kim
- CE Jones
- Cecelia Webster
- Chang-Yub Kim
- CR Lowe
- D Agren
- E Reisler
- EH Bursey
- G Hu
- G Loyola-Guzman
- GM Cooper
- Heungbok Kim
- HM Berman
- J Newman
- J-F Yu
- JJ Witt
- Justin K. M. Roberts
- Juthamas Kositsawat
- K Kawai
- L Stein
- L-L Chen
- Li-Wei Hung
- M Strong
- M Vedadi
- MD Goldberg
- MY Arica
- N Stols
- NE Chayen
- PDG Dean
- RK Scopes
- S Subramanian
- T Bergfors
- TC Terwilliger
- Thomas C. Terwilliger
- UK Laemmli
- V Tereshko
- W Vongsangnak
- X Gao
- Z Otwinowski
- ZS Derewenda
- Publication venue
- Springer Netherlands
- Publication date
- 01/01/2012
- Field of study
Ligands interacting with Mycobacterium tuberculosis recombinant proteins were identified through use of the ability of Cibacron Blue F3GA dye to interact with nucleoside/nucleotide binding proteins, and the effects of these ligands on crystallization were examined. Co-crystallization with ligands enhanced crystallization and enabled X-ray diffraction data to be collected to a resolution of at least 2.7 Å for 5 of 10 proteins tested. Additionally, clues about individual proteins’ functions were obtained from their interactions with each of a panel of ligands
Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
- Author
- A. Mohammed Kalakwa
- A. Nemer Ayoub
- Abantanga Francis A.
- Abatli Safa' Jamal
- Abbas Wisam
- Abbo Olivier
- Abdelbaqi Reem
- Abdelhady Dina Sobhy
- Abdelhafez Mohammad Omar Mohammad
- Abdelhamid Sultan S.
- Abdelmaksoud Sherif
- Abdelmoumen Roua
- Abdelmutalib Fakereldeen
- Abdul-Mumin Alhassan
- Abduljawad Fatima Mousa
- Abdullah Fizan
- Abdullah Mohd Yusof bin
- Abdulraheem Nurudeen
- Abdulrahman Alaa
- Abdulsalam Moruf Adekunle
- Abdunomonovich Dekhkonboev Avazjon
- Aboelela Ahmed
- Abouheba Mohamed
- Abrahamsson Kate
- Abrunhosa Matias Marcia
- Abu-Nejmah Fawzi
- Abuajaila Abdulsalam
- Abuattaya Adham Ashraf
- Abubakar Auwal M
- Abueideh Ahmad
- Abuhayyeh Husam Aldean
- Abuhlega Ma'aly A.
- Abukhalaf Sadi
- Abumunshar Ali Abdelhay
- Acuna Gaston
- Adams Stephen
- Adamu Sani
- Adanan Mohd Fitri Shukri bin Mohamed
- Adawi Ihda
- Adawi Samer
- Adawy Ahmad
- Ade-Ajayi Niyi
- Adegboyega Rilwan
- Ademuyiwa Adesoji
- Adesanya Opeoluwa
- Adhiwidjaja Cathline Freya
- Adofo-Ansong Nana
- Agboola Titiloye Hannah
- Agelebe Efeturi
- Aguilar Aguilar Faye
- Aguilar Gargurevich Prince Pamela
- Aguirre-Lopez Pastor
- Agulham Miguel Angelo
- Ahmad Hira
- Ahmad Zahidah Adlynee Haji
- Ahmed Hazem
- Ahmed Mahmoud Abdelfattah
- Ajai Olalekan Temitope
- Ajao Emmanuel Akinlabi
- Ajiboye Olalekan S.
- Ajrami Yara
- Ajwa Ahmad Elian Abu
- Akan M. Eren
- Akhbari Melika
- Akhter Nadeem
- Akova Fatih
- Al-Attar Hala M.
- Al-Halbouni Layana
- Al-Mamun Abdullah
- Al-Mayoof Ali Farooq
- Al-Momani Hashem M.
- Al-Mouakeh Ahmad
- Al-Rayyes Maisara
- Al-saleem Hasan Subhi Hasan Abu
- Al-Salhi Ashraf Ayman
- Al-Shwaikh Samar H.
- Al-Slaibi Ibrahim
- Al-Taher Raed Nael
- Al-Taher Raed Nael
- Al-Tammam Hiba
- Alakaloko Felix
- Alamrain Abdulwhhab Ayman Abu
- Alanguia Chipana Cathy Lee
- Alattas Khalid
- Alberto Carlos
- Albozidi Aya
- Alcántara Elvyn
- ALDIRAWI MOHAMMED A. M.
- Alebbini Mohanad Mutasem
- Alfoghi Mabroka
- Algabri Hayder Nadhim Obaid
- Alglaib Mohammed Meftah
- Alhamid Ahmad
- Alhamid Aos
- Alhassan Priscilla
- Ali Hassan
- Ali Karim Osamy
- Ali Liza
- Ali Mansour
- Alijla Sharif
- Alijla Sharif S.
- Aliwisat Ahmad Hasan
- Aljaboo Hajir
- Aljadidi Wesal Omar F. Saied
- Aljarad Ziad
- Alkareem Raghad mohammad abdu
- Almada Suad Ahmed
- Almadhoun Walaa
- Almasri Murad
- Almeida Aguiar Arthur
- Almeida Giovana
- Almengar Inas
- Almohamady Hisham
- Almosaibli Mohammad
- Almusleh Tasneem Fathi Hasan
- Alnaeri Ali
- Alnahhal Khaled
- Alonso Verónica
- Alosta Hasan Mustafa
- Alqarajeh Firas
- Alqor Mohammad Omar Ibrahim
- Alsaadi Nijmeh Nasser
- Alsaggaf Ameen
- Alsaied Amer
- Alser Mohammed
- Alser Osaid H.
- Alshaikhkhalil Haya Abdulnasser Ali
- Alshehri Abdullah
- Altaweel Ahmed
- Altın Merve
- Altokhais Tariq
- Altomi Mohamed
- Alturki Fahad
- Alvarado Zelada Jackelyne
- Alves Dutra da Silva Érika
- Alwadia Soha Marwan Salem
- Alwaggaa Nouriyah Ali
- Alzamari Ainaa Ata Mohammad
- Alzate Gallego Edgar
- Alzeer Asmahan Mohammad Suliman
- Alzerei Sulaiman T.
- Alzraikat Sayel H.
- Alzubair Afnan
- Alzughayyar Tareq Z.
- Amad Mohamed
- Amado Fernando
- Amaechi Chukwubinyelum
- Amah Christopher Chim
- Amarin Justin Z.
- Amarin Marzouq
- Ambriz-González Gabriela
- Ameh Emmanuel
- Amjad Muhammad Bin
- Amoabin Afua Amoabin
- Anatole Nzanzu
- Anatole Nzanzu Kipata
- Anaya Dominguez Marlene
- Anaya Firas
- Andrade Jerhy
- Andreussi Lorna
- Anicama Elias Rocio
- Annajjar Mohammad hasan
- Anntinea Jessmine
- Antunes Amanda
- Antunez-Mora Alexandra
- Anyomih Theophilus Teddy Kojo
- Anzelewicz Stefan
- Apaza Leon Jose Luis
- Appeadu-Mensah William
- Arabiat Esraa
- Arafa Mohamed Ahmed
- Arafat Hasan
- Aragão Liliana
- Arancibia Gutiérrez Elsa
- Aranda Sánchez Cristian Irela
- Arar Ahmad Samih
- Arauco Jenny
- Arbab Hana
- Arboleda Jenny
- Aremo Anuoluwapo
- Arnadóttir Helena
- Arnaud Alexis P
- Arnold Marion
- Arnoletto Lucia Beatriz
- Arrmali Saddam
- Arrmalli Lina Ali
- Arshad Muhammad
- Arthur Felicity
- Arul Suren
- Ashour Dina Ayman
- Ashour Yara shareef
- Aslan Yakup
- Aspirot Ann
- Assi Ahmadfateh
- Assi Muath Abdelrahem Fuad
- Astudillo Miguel
- Atatri Yazid yousef mahmoud
- Atta Ahmed
- Attia Alaa Mobarak
- Avile Romina
- Avolio Luigi
- Awad Hadeel
- Aydin Emrah
- Aykut Merve
- Ayque Rosas Fernando
- Aziz Dayang Anita Abdul
- Ba'baa' Basheer
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- Baker Wisam
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- Bamanga Ahmed
- Baniowda Muath A. M.
- Bao Xiaozhou
- Barauskas Vidmantas
- Barbosa Patricia Reis
- Baseggio Natalia
- Bashir Fatma
- Bashir Muhammad Kashif
- Bassan Gonçalves Paulo César
- Bataineh Ziad A.
- Batal Mohammad Mohannad
- Bazozi Hana Milad
- Beasley Spencer
- Becker Karin
- Belmino Gadelha Aluísio Augusto
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- Blanc Thomas
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- Borbonet Daniel
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- Bradshaw Kate
- Bragagnini Paolo
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- Bravo Mauro Nicolas
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- Brunero Marco
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- Bujarimin Ahmad Shafiee bin
- Bulnes Mendizabal David
- Burks Stephen S.
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- Cornwall Hannah
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- Cunningham Aaron
- Czauderna Piotr
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- da Silva Augusto Maria Lucia
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- Dalek Noor Fa'izatul Rahil Ambok
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- Dass Anthony
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- Dominguez Danny
- Donglai Hu
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- dos Santos Dias André Iván Bradley
- Dosselman Luke J.
- Douiri Abdel
- Drah Weam
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- Ebeido Annan
- Egbuchulem Ifeanyichukwu Kelvin
- Ejinkeonye Eze Chukwuemeka
- Ekenze Sebastian Okwuchukwu
- Ekwunife Okechukwu Hyginus
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- Elayeb Abdallah
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- Elewaily Mohamed
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- Elgammudi Mala
- Elghazaly Shrouk Mahmoud
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- Elhadi Muhammed
- Elhajjaji Yasmine Ali
- Elhattab Ahmad
- Elisante Joseph
- Elkaloush Abdullahn Abdousalam
- Elkhazmi Ebtesam Othman Abdulsalam
- Elmenam Mohamed Abd
- Elmzyyen Aya Mahmoud
- Elrais Safa Abdal
- Elsadek Menan Ahmed
- Elsaied Adham
- Elshaer Omar Adly
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- Elstad Maria
- Elzohiri Mohamed
- Elzowawi Fathi
- Emam Omar Sameh
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- Hagander Lars
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- Hammond Philip
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- Li Haijing
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- Li Zhongrong
- Liang Liang
- Liljesthrom Karen
- Lim Felicia
- Lin Nicole
- Lindert Judith
- Lino Urquizo Marcelo Mauricio
- Liu Yang
- Liubsys Arunas
- Liukitithara Sirima
- Ljuhar Damir
- Llap Unchón Genaro
- Lobos Pablo
- Lodhia Jay
- Loo Neyra Maria Susana
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- Lopes Teixeira Ferdinando Danielle
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- Løfberg Katrine
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- Martins Bianca M. R.
- Martínez Hernández Magro Nestor
- Mary Koshy Roshine
- Massry Nasrallah Ashraf Al
- Matour Bashar M.
- Mayaleh Abdelrazzaq Abu
- Mbonicura Jean Claude
- Mbonisweni Akhona
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- McColl Makepeace Lydia
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- Misk Rami Anwar
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- Mustufa Hamassat
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- Mwai Timothy
- Nageh Mohammad
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- Patkowski Dariusz
- Patzer Ludwig
- Pauzi Siti Farhan Moh
- Paz Soldan Carolina
- Pernik Mark N.
- Peycelon Matthieu
- Peña Padilla Christian
- Peñarrieta Daher Alejandro
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- Pos Lucie
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- PT Sundeep
- Puentes Maria Consuelo
- Puglia Paul
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- Quiles Corona Moises
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- Quran Thekraiat M. Al
- Qureshi Taimur
- Qutishat Hibah
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- Raboe Enaam
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- Ramos Yna
- Rani Zarqa
- Rasaki Aliu
- Rashid Sakina
- Rashwan Hayssam
- Ravetta Pablo
- Ravi Krithi
- Raymond Kwizera Jean
- Raza Rafee
- Razak Rahilah binti Abd
- Reda Ahmed
- Rehman Wajeeh ur
- Renaux Petel Mariette
- Rengura Cecilia
- Reuter Cristina
- Rex Dean
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- Rissmann Anke
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- Rivera Alvarez Julio
- Roberts Charles A.
- Roberts Kiera
- Roberts Rebecca
- Rojas Nair
- Rolle Udo
- Romano Piero Giovanni
- Romero Manteola Enrique
- Roszkiewicz Anna
- Ruan Weiwei
- Rudolfson Niclas
- Ruiz de Temiño Bravo Mercedes
- Ruzgar Nensi
- Rygl Michal
- S. Alkali Yahya
- Saad Alshaimaa M.
- Saad Mahmoud M.
- Sabbatini Stella
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- Saleem Ayesha
- Saleem Muhammad
- Saleh Amr
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- Salinas Barreto Juan Jose
- Salinas Vicente
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- Sferco Carlos Ariel
- Shabana Osaid Shaher
- Shahbal Swaleh
- Shaheen Ahmad Ashraf
- Shaheen Nureddin
- Shaklawoon Aisha
- Shalaby Amr
- Shalaby Hanin
- Shalluf Hawa Ahmed
- Shan Cheah Hui
- Sharabati Fadwa
- Sharabati Mutassem
- Sharif Muhammad
- Sharif Randa Alamen M
- Shaw Kenneth
- Shehada Mohammed
- Shehu Ibrahim
- Sheir Hesham
- Sherer Karen
- Sherzad Ajmal
- Shiha Eman Abu
- Shikha Anas
- Shinondo Patricia
- Shnishah Aya Essam
- Shokri Hajer Ali
- Shonubi Amo
- Shoubaki Ali
- Shu Qiang
- Shyaka Gashugi Ian
- Siddiqui Sabina M
- Sidler Daniel
- Sigalet David
- Sihem Brahimi
- Sikwete Guigui
- Siles Hinojosa Alexander
- Silva Beltrán Nathalia
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- Silva Yanina
- Sim Marcus
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- Sindi Omar
- Singer Georg
- Singh Michael
- Sivaraj Jayaram
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- Slavkovi Andjelka
- Slavkovic Milan
- Smith Emily Rose
- Soares de Fraga José Carlos
- Sobrero Helena
- Soccorso Giampiero
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- Sola Juan
- Solanki Meghna
- Soliman Nourhan Akram
- Son Joonhyuk
- Song Eung song
- Soomro Aqil
- Sotelo Sanchez Jennifer
- Souhem Touabti
- Soula Enas
- Souza Barros Beatriz
- Souza Machado Ana Beatriz
- Sowe Babucarr
- Sriniworn Anan
- St-Louis Etienne
- St-Vil Dickens
- Stark Domitille
- Stojanovic Miona
- Stringer Mark
- Strumila Arunas
- Sueiras Ines
- Sulca Cruzado Gladys Johana
- Suleiman Faruk
- Sultana Sadia
- Suradi Haya H.
- Sutcliffe Jonathan
- Suzana Trein Cristine
- Suzen Alev
- Svensson Emma
- Svirsky Alexander
- Swessi Hisham
- Syed Shahnoor
- Syovata Francisa
- Szklarz Maria Tatiana
- Sánchez Paredes Vicente
- Sönmez Kaan
- T Shajin
- T. Sambo Yusuf
- Tababa Osama
- Tabari Ahmad Khaleghnejad
- Tabiri Stephen
- Tadesse Amezene
- Tahyneh Abdulraheem Adnan Abdulraheem
- Takrouney Mohammed Hamada
- Talat Nabila
- Tallaa Mohamed Anwer El
- Tamada Horácio
- Tamaddun Hafatin Fairos bt
- Tang Weibing
- Tanimola Adebayo Gbenga
- Tanming Patchareeporn
- Tanny Sharman Tan
- Tantush Sara Abobaker
- Tarabishi Ahmad Sankari
- Tarek Ahmed
- Tarmohamed Murad
- Tarniba Sara Ali
- Tarrado Xavier
- Tasker David
- Teague Warwick
- Telles Leila
- Temilade Bolarinwa Bolanle
- Teo Rufinah
- Teran Araceli
- Terzic Sabina
- Testoni Daniela
- Thaiwatcharamas Kanokrat
- Thiessen Jesh
- Thomas Amy Hughes
- Thomas Gordon
- Thomas Mark C
- Thompson Hannah
- Till Holger
- Tillig Bernd
- Tinoco Guzmán Nestor Julien
- Tobor Szymon
- Toczewski Krystian
- Tom Alan
- Toplicic Djordje
- Toral Eliana
- Torres Miranda Cesar
- Torres Picón Cintya Maria de Jesus
- Torres-Canchala Laura
- Toselli Luzia
- Touabti Souhem
- Toufik Iaiche Achour
- Tovar Gutierrez Natalia
- Trainba Sara
- Trigoso Mori Fernando
- Trindade Deyl Rafael
- Trojanová Barbora
- Trypens Agata
- Tumi Mohamed
- Tuyishime Eugene
- Türkyılmaz Canan
- Türkyılmaz Zafer
- Ubhi Harmony
- Ugwu Jideofor O
- Ugwunne Chuka A
- Ulasi Ikechukwu
- Ullrich Sarah
- Vacek Jonathan
- Vaitkiene Agota
- Valencia Santiago
- Valeria Pelussi
- Valerio-Vazquez Rafael
- Vanis Nedim
- Vaquila Justo
- Varela Maria Florencia
- Vasquez Matos Juan Pedro
- Vatta Fabrizio
- Vega Centen Stephany
- Velaña Junior
- Vellusamy V Muthualhagi M
- Venant Ntakarutimana
- Venkatraman Soundappan Sannappa
- Verdeata Roxana
- Verduga Ivan
- Verduga Leonardo
- Vergara Carolina
- Verkauskas Gilvydas
- Veronica Sofficci
- Vervoort Dominique
- Vianney Butoyi Jean Marie
- Vida Lucian
- Vidal Cristian R. Zalles
- Vierboom Liam
- Villalba Villalba Araceli
- Villegas Silva Raúl
- Vinskaite Asta
- Vos Corné de
- Vosoughi Armin
- Wafa Tamer
- Walker Gregor
- Wang Jinhu
- Wang Peng
- Waseem Basma
- Weeratunga Naveen
- Weiszewsk Alicja
- Wen Gang
- Werneck Raposo Juliana
- Wester Tomas
- Wijekoon Naveen
- Wilke Alexandra
- Williams Isabelle
- Williams Omolara
- Williams Regan
- Win Win Sabai Phyu
- Wishah Bisan D. M.
- Wishah Nidal
- Wissanji Hussein
- Wolak Przemyslaw
- Wolny Agnieszka
- Wong Janice
- Wong Marilyn
- Wright Naomi Jane
- Wu Guowei
- Wyrzykowski Dariusz
- Xiaodong Guo
- Xie Hua
- Yacoub Mina A.
- Yaghi Bashar
- Yaghi Dua Hasan
- Yalcinkaya Ali
- Yang Hee-Beom
- Yanis Ahmad H.
- Yanowsky Reyes Guillermo
- Yao Yang
- Yapo Benjamin
- Yarza Fernández Jessica
- Yeniay Aslı Öztürk
- Yola Mariya Mukhtar
- Yong Feng
- Youn Joong Kee
- Yousuf Hina
- Yu Mengnan
- Yu Raisa
- Yuen Quah Soong
- Yuldashev Rustam Z.
- Yunus Aayenah
- Za'nouneh Faris J. Abu
- Zaghlol Louay Y.
- Zahari Dato' Dr Zakaria bin
- Zain Mostafa
- Zaman Azrina SK
- Zanellato Josiane Bernartt
- Zarwawi Ahmad Zulhisyam bin
- Zea-Salazar Luis Enrique
- Zeinelabdeen Ali
- Zhao Xiaoxia
- Zhu Jianming
- Zhu Libin
- Zidan Mazen
- Zivanovic Dragoljub
- Zottis Barcelos Fabricio
- Zreeg Dafer abdulhakim . S.
- Zurikat Rajai O.
- Zvizdic Nada
- Zvizdic Zlatan
- Çekiç Bahanur
- Çelik Müge
- Özçelik Zerrin
- Şeref Kıvanç
- Šafus Antonín
- Škvařil Jan
- Štichhauer Radek
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Summary
Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally.
Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies
have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of
the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income
countries globally, and identified factors associated with mortality.
Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to
hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis,
exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a
minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical
status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary
intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause,
in-hospital mortality for all conditions combined and each condition individually, stratified by country income status.
We did a complete case analysis.
Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital
diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal
malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome
countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male.
Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3).
Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income
countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups).
Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome
countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries;
p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients
combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11],
p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20
[1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention
(ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety
checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed
(ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of
parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65
[0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality.
Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome,
middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will
be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger
than 5 years by 2030
Postscript to his brothers: Reading Alonso De Sandoval's De Instauranda Aethiopum Salute
- Author
- Acosta José de S.J.
- Acosta José de S.J.
- Acosta Saignes Miguel
- Barry William A. S.J.
- Bilinkoff Jodi
- Bowser Frederick P.
- Bowser Frederick P.
- Brading David
- Cassani Joseph S.J.
- Cohen Thomas M.
- Endean Philip S.J.
- Frois Luis S.J.
- Gonçalves Da Câmara Luis
- Gonçalves Sebastião
- Guzman Luis S.J.
- Kolvenbach Peter-Hans S.J.
- Kreider Alan
- Loyola Ignatius
- Loyola Ignatius
- Loyola Ignatius
- Lucena João de.
- Martin A. Lynn.
- Mattoso Kátia M.
- McClendon James William
- Mira João Manoel Lima.
- Morgan Ronald J.
- Morgan Ronald J.
- Morgan Ronald J.
- O'Malley John W. S.J.
- Olsen Margaret M.
- Pacheco Juan Manuel S.J.
- Pagden Anthony
- Pérez De Ribas Andrés S.J.
- Ramos Domingo José
- Reff Daniel T.
- Ribadeneira Pedro De S.J.
- Ribadeneira Pedro De S.J.
- Rodriguez G.
- Ronald J. Morgan
- Ruiz De Montoya Antonio S.J.
- Sandoval Alonso de S.J.
- Santagata Saverio S.J.
- Stroup George W.
- Vila Vilar Enriqueta
- Ward Michael
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Gestational diabetes mellitus is associated with increased pro-migratory activation of vascular endothelial growth factor receptor 2 and reduced expression of vascular endothelial growth factor receptor 1
- Author
- A American Diabetes
- A Ghosh
- AK Olsson
- C Escudero
- C Escudero
- C Wadsack
- Carlos Escudero
- Claudio Aguayo
- DA Sacks
- EA Dubova
- EM Wendland
- Enrique Guzman-Gutierrez
- F Mac Gabhann
- Felipe Troncoso
- G Daskalakis
- G Desoye
- G Desoye
- Gernot Desoye
- H Bai
- HM Eilken
- IP Yang
- J Huynh
- J Janota
- Jesenia Acurio
- JS Gill
- JS Gill
- K Holmqvist
- Kurt Herlitz
- L Leach
- L Leach
- L Pietro
- M Gauster
- M Jirkovska
- M Lappas
- M Marini
- M Shibuya
- M Shibuya
- Marcelo Gonzalez
- Marco Loyola
- Maria Cristina Vinci
- Meriem Rezgaoui
- MT Dellinger
- P Carmeliet
- P Fernandez
- P Lassus
- Patricio Bertoglia
- Q Meng
- R Madazli
- R Plitman Mayo
- S Cvitic
- S Helske
- S Koch
- S Rey
- S Veeraswamy
- SA El-Tarhouny
- SH Su
- T Matsumoto
- T Takahashi
- TM Mayhew
- TT Chen
- U Hiden
- V Anna
- Y Latron
- Z Sun
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Photosynthetic ATPases: purification, properties, subunit isolation and function
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- A Baccarini-Melandri
- A Baccarini-Melandri
- A Binder
- A Binder
- A Gepshtein
- A Gepshtein
- A Gepshtein
- A Hochman
- A Loyola-Guzman
- A Viale
- A Watanabe
- AE Senior
- AE Senior
- AE Senior
- AF Knowles
- BA Baird
- BA Baird
- BC Johansson
- BR Selman
- C Bengis-Garber
- C Carmeli
- C Kayalar
- CA Price
- CJ Howe
- CJ Howe
- CS Andreo
- CS Andreo
- CW Akey
- D Herrin
- D Khananshvili
- D Khananshvili
- DA Harris
- DA Harris
- DB Datta
- DL Foster
- DW Deters
- E Benedetti De
- EH Moase
- ET Krebbers
- F Farron
- F Farron
- FA McEvoy
- FS Esch
- FS Esch
- FW Hulla
- G Girault
- G Zurawski
- GE Anthon
- GE Blair
- H Deno
- H Hesse
- H Hoffman-Falk
- H Kanazawa
- H Müller
- H Sakurai
- H Stan-Lotter
- H Strotmann
- H Strotmann
- H Tiedge
- HA Lardy
- HH Paradies
- HH Paradies
- HJ Lubberding
- HM Younis
- HM Younis
- HM Younis
- HS Penefsky
- HS Penefsky
- HW Müller
- IA Kozlov
- IC Chang
- J Lunardi
- J-D Rochaix
- JA Steele
- JE Walker
- JE Walker
- JG Wise
- JJ Czarnecki
- JS Kahn
- JT Heij de
- JTO Kirk
- JV Moroney
- JV Moroney
- K Shinozaki
- K-H Süss
- K-H Süss
- L Owers-Narhi
- L Posorke
- LC Cantley
- LC Cantley
- LC Cantley
- LR Mendiola-Morgenthaler
- M Avron
- M Avron
- M Futai
- M Saraste
- M Satre
- M Wolf
- M Yoshida
- M Yoshida
- M Yoshida
- M Yoshida
- M-F Carlier
- MA Tiefert
- MA Weiss
- ME Pullman
- MF Bruist
- MJ Runswiek
- MM Margulies
- MW Gray
- N Nelson
- N Nelson
- N Nelson
- N Nelson
- N Nelson
- N Nelson
- N Shavit
- N-H Chua
- P Mitchell
- P Mitchell
- P Westhoff
- P-Y Bouthyette
- PD Bragg
- PD Bragg
- PR Whitfeld
- R Béliveau
- R Humbert
- R Nechushtai
- R Nechushtai
- R Pougeols
- R Rott
- RA Ravizzini
- RD Todd
- RE Kneusel
- RE McCarty
- RG Piccioni
- RH Fillingame
- RJ Berzborn
- RJ Ellis
- RJ Ellis
- RJ Wagenvoord
- RL Cross
- RL Cross
- S Lien
- S Lien
- S Merchant
- S Merchant
- S Ohta
- S Philosoph
- S Philosoph
- S Philosoph
- S Selman-Reimer
- S Selman-Reimer
- SD Dunn
- SP Myers
- T Bakker-Grunwald
- T Noumi
- U Pick
- U Pick
- V Shoshan
- V Shoshan
- VK Vambutas
- Y Hochman
- Y Hochman
- Y Kagawa
- Y Kagawa
- Y Kagawa
- Y Kagawa
- Y Kagawa
- Z Gromet-Elhanan
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1985
- Field of study
Chest pain due to coronary artery disease alters stress neuropeptide levels: Potential implications for clinical assessment
- Author
- A. Anastasio
- A. Angelini
- A. Angelini
- A. Aranega
- A. Aranega
- A. Ardelean
- A. Arias
- A. Astvatsatryan
- A. Astvatsatryan
- A. Atkinson
- A. Atkinson
- A. Beer
- A. Beltrami
- A. Biondi
- A. Biondi
- A. Bogdanova
- A. Bogdanova
- A. Bravin
- A. Bukowska
- A. Bukowska
- A. Castro Beiras
- A. Centeno
- A. Chmura-Skirlinska
- A. Christ
- A. Colantuoni
- A. Czikora
- A. Czikora
- A. Cziraki
- A. Darago
- A. De La Rosa Sanchez
- A. Dendorfer
- A. Deussen
- A. Diez
- A. Dinnyes
- A. Distante
- A. Distante
- A. Distante
- A. Duelsner
- A. Fontes-Sousa
- A. Fontes-Sousa
- A. Francke
- A. Frobert
- A. Fucili
- A. Fusco
- A. Giannoukas
- A. Ginion
- A. Goerlach
- A. Goette
- A. Goette
- A. Gonzalez-Loyola
- A. Gorbe
- A. Gorbe
- A. Gromotowicz
- A. Guven
- A. Haj Khelil
- A. Halestrap
- A. Heagerty
- A. Hoeper
- A. Ibatov
- A. Ibatov
- A. Ibatov
- A. Iqbal
- A. Izzard
- A. Jablonska
- A. Jobs
- A. Jovelic
- A. Kadner
- A. Kandasamy
- A. Kaplan
- A. Kaumann
- A. Kaya
- A. Khalid
- A. Kharlamov
- A. Koller
- A. Koutsiaris
- A. Kristof
- A. Kurtz
- A. Kwater
- A. Lebreiro
- A. Lebreiro
- A. Leite-Moreira
- A. Leite-Moreira
- A. Leite-Moreira
- A. Leite-Moreira
- A. Leuner
- A. Lewis
- A. Loot
- A. Ludwig
- A. Lymperopoulos
- A. Lyon
- A. Makarov
- A. Makhro
- A. Makhro
- A. Mansurov
- A. Mayr
- A. Mikhailov
- A. Mugelli
- A. Mugelli
- A. Neji
- A. Nemeth
- A. Panzenboeck
- A. Perrot
- A. Perrot
- A. Petry
- A. Piirsoo
- A. Pries
- A. Raffaelli
- A. Rampazzo
- A. Rankin
- A. Ratajska
- A. Remaley
- A. Renger
- A. Rodriguez-Sinovas
- A. Rodriguez-Sinovas
- A. Rutkovskiy
- A. Rutkovskiy
- A. Ruusalepp
- A. Saba
- A. Schmeisser
- A. Schmeisser
- A. Schober
- A. Schober
- A. Schober
- A. Schrepper
- A. Schrepper
- A. Seymen
- A. Siegbahn
- A. Soldo
- A. Soldo
- A. Stankiewicz
- A. Surdacki
- A. Switalski
- A. Szunyog
- A. Toso
- A. Toso
- A. Toso
- A. Toth
- A. Toth
- A. Trafford
- A. Tsaousi
- A. Vanderper
- A. Varro
- A. Varro
- A. Varro
- A. Welz
- A. Wiedon
- A. Woodiwiss
- A. Workman
- A. Yemm
- A. Yildiz
- A. Zahradnikova
- A. Zahradnikova
- A. Zakrzeska
- A. Zakrzewicz
- A. Zambon
- A. Zimmer
- A. Zvara
- A.-S. Tanko
- B. Bauce
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- B. Binder
- B. Chen
- B. Chen
- B. Ciszek
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- B. Desai
- B. Eichhorn
- B. Eichhorn
- B. Fleischmann
- B. Fuglested
- B. Haubner
- B. Hivert
- B. Hivert
- B. Horvath
- B. Krausgrill
- B. Krausgrill
- B. Levkau
- B. Lubiszewska
- B. Luzak
- B. Merkely
- B. Merkely
- B. Metzler
- B. Molins
- B. Nurnberg
- B. Pieske
- B. Pieske
- B. Prendergast
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- B. Redwan
- B. Seidel
- B. Sochanowicz
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- B. Thiede
- B. Toffoletto
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- C. Weber
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- D. Aksentijevic
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- D. Garcia-Dorado
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- D. Sorriento
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- D. Tedeschi
- D. Tedeschi
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- E. Bozas
- E. Brauer-Krisch
- E. Carturan
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- E. Chabielska
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- E. Cipolletta
- E. Dedok
- E. Dyer
- E. Ercan
- E. Erika Amstalden Van Hove
- E. Faggin
- E. Fleck
- E. Gao
- E. Holzwart
- E. Holzwart
- E. Iliodromitis
- E. Jorge
- E. Kefaloyianni
- E. Khodjaeva
- E. Kletsiou
- E. Kraigher-Krainer
- E. Ksiezycka-Majczynska
- E. Lesnefsky
- E. Liepins
- E. Lizanecz
- E. Lopez
- E. Martins
- E. Martins
- E. Miro-Casas
- E. Mistrova
- E. Orlova
- E. Papathanassoglou
- E. Papini
- E. Pena
- E. Polakova
- E. Polidano
- E. Polidano
- E. Ricart
- E. Russo
- E. Scholz
- E. Scoditti
- E. Scoditti
- E. Scoditti
- E. Seppet
- E. Serena
- E. Serena
- E. Stachurska
- E. Sulyok
- E. Tsironi
- E. Tuncay
- E. Vavers
- E. Wettwer
- E. Wettwer
- E. Wettwer
- E. Wright
- E. Zitron
- F. Asgun
- F. Azibani
- F. Azibani
- F. Bellandi
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- F. Bellandi
- F. Ben Mohamed
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- F. Burgbacher
- F. Chorro
- F. Deak
- F. Di Lisa
- F. Ercan
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- F. Grego
- F. Haugen
- F. Hertel
- F. Jeukens
- F. Kolar
- F. Kolk
- F. Kuck
- F. Liu
- F. Liu
- F. Liu
- F. Liu
- F. Lynch
- F. Mohr
- F. Mohr
- F. Molla
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- F. Norheim
- F. Novak
- F. Revnic
- F. Revnic
- F. Rochais
- F. Roehl
- F. Sari
- F. Seifriz
- F. Sheeran
- F. Stillitano
- F. Tournoux
- F. Tournoux
- F. Wang
- F. Welke
- G. Ambrosio
- G. Bagavananthem Andavan
- G. Balconi
- G. Balconi
- G. Baumann
- G. Chiellini
- G. Ciliberti
- G. Csanyi
- G. D'amati
- G. Deriu
- G. Duerr
- G. Fiskum
- G. Foldes
- G. Foldes
- G. Francolini
- G. Germano
- G. Giobbe
- G. Hao
- G. Harmati
- G. Hasenfuss
- G. Heusch
- G. Iaccarino
- G. Iaccarino
- G. Kalachova
- G. Kararigas
- G. Klug
- G. Kocsis
- G. Kocsisne Fodor
- G. Kojda
- G. Marshall
- G. Maurer
- G. Ng
- G. Ng
- G. Ng
- G. Norton
- G. Panic
- G. Rengo
- G. Santulli
- G. Santulli
- G. Schrot
- G. Siegel
- G. Strub
- G. Suchan
- G. Szabo
- G. Szabo
- G. Szabo
- G. Szucs
- G. Thiene
- G. Thiene
- G. Thiene
- G. Valen
- H. Blattmann
- H. Cingolani
- H. Daimi
- H. Dobrzynski
- H. Dobrzynski
- H. Graham
- H. Lehmann
- H. Lin
- H. Maechler
- H. Meyborg
- H. Morawietz
- H. Niessen
- H. Paur
- H. Schulten
- H. Seo
- H. Shimazaki
- H. Terlau
- H. Tevaearai
- H. Tillmanns
- H. Tillmanns
- H. Williams
- H. Xu
- H. Zhang
- H.-P. Schultheiss
- I. Agarkova
- I. Aggeli
- I. Barba
- I. Beis
- I. Bot
- I. Buschmann
- I. Castan-Laurell
- I. Diebold
- I. Edes
- I. Edes
- I. Falcao-Pires
- I. Falcao-Pires
- I. Falcao-Pires
- I. Findlay
- I. Findlay
- I. Fleming
- I. Horvath
- I. Khaliulin
- I. Kierzkowska
- I. Kiss
- I. Koncz
- I. Koslov
- I. Lang
- I. Mancini
- I. Petrushanko
- I. Piccini
- I. Russo
- I. Russo
- I. Rutkai
- I. Rutkai
- I. Srdanovic
- I. Studneva
- I. Trapero
- I. Tritto
- I. Uzunhasan
- I. Zahradnik
- J. Allegood
- J. Almeida
- J. Auquier
- J. Balligand
- J. Bernardes
- J. Boczan
- J. Breuss
- J. Cena
- J. Chibani
- J. Chin-Dusting
- J. Cinca
- J. Clarke
- J. Coote
- J. Coote
- J. Coote
- J. Dempster
- J. Dominguez
- J. Ferreiro Gutierrez
- J. Hamelet
- J. Hammond
- J. Herold
- J. Herold
- J. Hescheler
- J. Hescheler
- J. Hescheler
- J. Hescheler
- J. Hess
- J. Jakowitsch
- J. Jankowski
- J. Jeremy
- J. Kaufmann
- J. Krueger
- J. Kuka
- J. Laissue
- J. Li
- J. Li
- J. Liang
- J. Lobenhoffer
- J. Machado
- J. Magyar
- J. Maroski
- J. Martens-Lobenhoffer
- J. Matthes
- J. Morales
- J. Muller-Ehmsen
- J. Muller-Ehmsen
- J. Neckar
- J. Papp
- J. Papp
- J. Park
- J. Parker
- J. Pipis
- J. Pruefer
- J. R. Chiong
- J. Samuel
- J. Samuel
- J. Sanchez
- J. Schneider
- J. Simko
- J. Slavikova
- J. Strasser
- J. Sulicka
- J. Szemraj
- J. Vaage
- J. Vaage
- J. Van Der Velden
- J. Vanoverschelde
- J. Voelkl
- J. Vogel
- J. Waltenberger
- J. Waltenberger
- J. Waltenberger
- J. Wenzel
- J. Witowski
- J. Woitzik
- J. Wojta
- J. Yanni
- J. Zhang
- J.-F. Renaud
- J.-M. Daniel
- K. Albrecht
- K. Andrews
- K. Ben Hamda
- K. Bender
- K. Boengler
- K. Brack
- K. Brack
- K. Brack
- K. Dharmashankar
- K. Dibb
- K. Farrell
- K. Farrell
- K. Golba
- K. Gordon
- K. Hirschberg
- K. Hirschberg
- K. Hirschberg
- K. Huber
- K. Jutzy
- K. Kappert
- K. Kappert
- K. Kappert
- K. Khalikulov
- K. Korybalska
- K. Kupai
- K. Makinen
- K. Matschke
- K. Michaud
- K. O'shea
- K. O'shea
- K. Ort
- K. Paju
- K. Pilichou
- K. Poddar
- K. Preissner
- K. Schenk
- K. Schenk
- K. Schmidt
- K. Sipido
- K. Skopp
- K. Stangl
- K. Stenslokken
- K. Stenslokken
- K. Walsh
- K. Watanabe
- K. Woodburn
- L. Badimon
- L. Balwicki
- L. Barandi
- L. Becker
- L. Bertrand
- L. Cervo
- L. Evert
- L. Fabritz
- L. Fazal
- L. Fazal
- L. Ferron
- L. Fornai
- L. Fortmueller
- L. Gomez
- L. Houston-Feenstra
- L. Hue
- L. Kadaja
- L. Lacerda
- L. Lopes-Conceicao
- L. Lourido
- L. Maier
- L. Mainar
- L. Mariero
- L. Mariero
- L. Mateuszuk
- L. Monserrat
- L. Opie
- L. Opie
- L. Pagliani
- L. Pardali
- L. Pott
- L. Puskas
- L. Puskas
- L. Raimondi
- L. Sartiani
- L. Sartiani
- L. Sebag-Montefiore
- L. Staszewsky
- L. Staszewsky
- L. Tanini
- L. Tanini
- L. Tanini
- L. Virag
- L. Virag
- L. Wierucki
- L. Zelarayan
- M. Aberg
- M. Amato
- M. Amorim
- M. Anastasiou-Nana
- M. Bergmann
- M. Bettini
- M. Boyett
- M. Boyett
- M. Brandenburger
- M. Bucciantini
- M. Cabaravdic
- M. Canton
- M. Carluccio
- M. Carluccio
- M. Carluccio
- M. Castro
- M. Chottova Dvorakova
- M. D. Schneider
- M. Daemen
- M. Dambrova
- M. Deja
- M. Drab
- M. Fechner
- M. Fedrigo
- M. Fernandez-Alfonso
- M. Flueck
- M. Forteza
- M. Gajda
- M. Gassmann
- M. Gassmann
- M. Giannakopoulou
- M. Gil-Ortega
- M. Gladyshev
- M. Gomes
- M. Graeler
- M. Grebe
- M. Gunetti
- M. Halbach
- M. Halbach
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- M. Horn
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- M. Johnell
- M. Juszynski
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- M. Karck
- M. Kotoula
- M. Kovacevic
- M. Kruk
- M. Kruse
- M. Kruszewski
- M. Kuhlmann
- M. Kulzer
- M. Leoncini
- M. Leoncini
- M. Leoncini
- M. Ma
- M. Maciel
- M. Maggioni
- M. Maioli
- M. Maioli
- M. Maioli
- M. Malinowski
- M. Manni
- M. Marchini
- M. Martins
- M. Massaro
- M. Massaro
- M. Massaro
- M. Mioulane
- M. Mioulane
- M. Nazari-Jahantigh
- M. Nazari-Jahantigh
- M. Neubert
- M. Osterholt
- M. Paillard
- M. Penfold
- M. Petrovic
- M. Pirity
- M. Popescu
- M. Posch
- M. Posch
- M. Post
- M. Post
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- M. Puato
- M. Pyda
- M. Raths
- M. Rattazzi
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- M. Renner
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- M. Roosimaa
- M. Ruiz-Gayo
- M. Ruiz-Meana
- M. Ruiz-Meana
- M. Rus
- M. Schaefer
- M. Schaefers
- M. Schoepe
- M. Schoepe
- M. Schuchardt
- M. Schuchardt
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- M. Schwarzer
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- M. Senan
- M. Senan
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- M. Stefani
- M. Strach
- M. Szperl
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- M. Toelle
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- M.-C. Kienitz
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- N. Goncalves
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- N. Jost
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- P. Rainer
- P. Rainer
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- P. Stieger
- P. Stieger
- P. Stratford
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- S. Eigeldiger-Berthou
- S. Frascarelli
- S. Fratz
- S. Gasser
- S. Gasser
- S. George
- S. George
- S. Ghelardoni
- S. Harding
- S. Harding
- S. Harding
- S. Herzig
- S. Herzig
- S. Horman
- S. Hynie
- S. Inada
- S. Kaestner
- S. Khong
- S. Korkmaz
- S. Korkmaz
- S. Korkmaz
- S. Lecour
- S. Lecour
- S. Loganathan
- S. Loganathan
- S. Loganathan
- S. Lucke
- S. Maaoui
- S. Makaula
- S. Marston
- S. Masson
- S. Medunjanin
- S. Meiners
- S. Menazza
- S. Mohammed
- S. Mohammed
- S. Neef
- S. Neubauer
- S. Neubauer
- S. Olieslagers
- S. Pali
- S. Pepe
- S. Perlini
- S. Pfaffenberger
- S. Pimenta
- S. Pinho
- S. Radicke
- S. Radicke
- S. Ramasamy
- S. Rha
- S. Rungaruniert
- S. Sabatasso
- S. Schudeja
- S. Sharp
- S. Silva
- S. Slavic
- S. Soemantri
- S. Somers
- S. Sossalla
- S. Spiegel
- S. Suffredini
- S. Tachmitzi
- S. Tereshchenko
- S. Turi
- S. Vagnani
- S. Verbruggen
- S. Waldmuller
- S. Weinert
- S. Wos
- S. Yakushev
- S. Zatti
- S. Zatti
- S. Zervou
- T. Adam
- T. Banyasz
- T. Bass
- T. Canji
- T. Christ
- T. Coenen
- T. Csont
- T. Csont
- T. Csont
- T. Csont
- T. Denissevich
- T. Djordjevic
- T. Doenst
- T. Doenst
- T. Glibovskaya
- T. Grodzicki
- T. Heuft
- T. Huang
- T. Jedrzejczyk
- T. Kietzmann
- T. Klaas
- T. Kristian
- T. Larsen
- T. Maswanganyi
- T. Pizzetti
- T. Pizzetti
- T. Pizzetti
- T. Podramagi
- T. Popov
- T. Raastad
- T. Radovits
- T. Roleder
- T. Rywik
- T. Saric
- T. Saric
- T. Scanlan
- T. Schall
- T. Scheffold
- T. Suter
- T. Suvorava
- T. Szel
- T. Van Assche
- T. Van Berkel
- T. Zaglia
- T. Zdrojewski
- U. Kintscher
- U. Ravens
- U. Ravens
- U. Ravens
- U. Ravens
- U. Ravens
- U. Ravens
- U. Roessl
- U. Roessl
- V. Babes
- V. Babes
- V. Bargelli
- V. Bodi Peris
- V. Capuano
- V. Dao
- V. Djonov
- V. Fekete
- V. Fekete
- V. Fiorelli
- V. Furundzija
- V. Groppalli
- V. Jankowski
- V. Klenerova
- V. Maupoil
- V. Maupoil
- V. Mitkevich
- V. Nikolaev
- V. Petrov
- V. Regitz-Zagrosek
- V. Shulzhenko
- V. Shumavetz
- V. Shumavetz
- V. Spinelli
- V. Stangl
- V. Sukumaran
- V. Szuts
- V. Szuts
- V. Tarcea
- V. Tchaikovski
- V. Titov
- V. Titov
- W. Azrozal
- W. Bielenberg
- W. Eijgelaar
- W. Han
- W. Han
- W. Koch
- W. Paulus
- W. Piotrowski
- W. Ruzyllo
- W. Schgoer
- W. Soenke
- W. Song
- W. Stanley
- W. Stanley
- X. Gao
- X. Li
- X. Li
- X. Li
- X. Li
- X. Li
- X. Ma
- X. Yang
- X. Zhao
- Y. He
- Y. Hu
- Y. Huang
- Y. Huang
- Y. Huang
- Y. Kashcheyeu
- Y. Kobayashi
- Y. Lin
- Y. Ma
- Y. Ma
- Y. Ma
- Y. Ma
- Y. Ostrovskiy
- Y. Ostrovskiy
- Y. Pelogeykina
- Y. Ruchon
- Y. Su
- Y. Yang
- Y. Yang
- Y. Yang
- Y. Yang
- Y. Zhao
- Z. Ajtay
- Z. Lenkey
- Z. Megyesi
- Z. Papp
- Z. Papp
- Z. Varga
- Z. Varga
- Z. Yigit
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2010
- Field of study
Rivaroxaban with or without aspirin in stable cardiovascular disease
- Author
- Abat M.
- Abatello M.
- Abdul Hafidz M. I.
- Abdul Rahim A. A.
- Abdullah W. M.
- Abe H.
- Abe M.
- Abe S.
- Abe Y.
- Abelson M.
- Abergel H.
- Abib E.
- Abitbul A.
- Abola M.
- Aboyans V.
- Abrantes J.
- Absi F.
- Abu Hassan M. R.
- Abu Kassim Z.
- Accassat S.
- Accini Diaz A.
- Accini Mendoza A.
- Accini Mendoza J.
- Acimic C.
- Acosta G.
- Actis M.
- Adamkova V.
- Adamo M.
- Adams K.
- Adler F.
- Agardi I.
- Agudelo Ramos L.
- Aguirre M.
- Agullo A.
- Ahmad H.
- Ahmed A.
- Ahuad Calvelo A.
- Ahuad Calvelo J.
- Ahuad Guerrero R.
- Aizawa Y.
- Ajax K.
- Akatsuka T.
- Akatsuka Y.
- Akhavuz O.
- Akiyama R.
- Akiyoshi H.
- Ako J.
- Al-Khalili F.
- Al-Qoofi F.
- Alagban C.
- Alarcon J.
- Alarcon V.
- Alarie P.
- Albertijn S.
- Albertsson P.
- Albisu Di Gennero J.
- Alcaraz J.
- Alcaraz L.
- Alcorano J.
- Ali I.
- Alianza M.
- Alings M.
- Alison M.
- Allegrini E.
- Almagro S.
- Almendrales L.
- Almroth H.
- Aloisi A.
- Alvarez D'Amelio A.
- Alvarez Damelio A.
- Alvarez M.
- Alvarez Y.
- Alwi S. M.
- Alzate J.
- Aman S.
- Amemiya H.
- Amemiya Y.
- Amerena J.
- Amir M. A.
- Amiya R.
- Amonchot A.
- Amorin R. C.
- An S.
- Anand S. S.
- Anderson J.
- Anderson T.
- Andersson T.
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- Ando M.
- Andrade G.
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- Andrew G.
- Andrioli V.
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- Zambonin GEC.
- Zamiti-Smondel A.
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- Zhuravleva E.
- Zhurina M.
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- Zimmermann EMB.
- Zimmermann S. L.
- Zoet-Nugteren S.
- Zorzo JAT.
- Zsary A.
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- Zubova E.
- Zuker S.
- Zukermann R.
- Zuleta I.
- Zuleta M.
- Zushi R.
- Zvi R.
- Zvi Y.
- Zwinnen W.
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2017
- Field of study
BACKGROUND: We evaluated whether rivaroxaban alone or in combination with aspirin would be more effective than aspirin alone for secondary cardiovascular prevention. METHODS: In this double-blind trial, we randomly assigned 27,395 participants with stable atherosclerotic vascular disease to receive rivaroxaban (2.5 mg twice daily) plus aspirin (100 mg once daily), rivaroxaban (5 mg twice daily), or aspirin (100 mg once daily). The primary outcome was a composite of cardiovascular death, stroke, or myocardial infarction. The study was stopped for superiority of the rivaroxaban-plus-aspirin group after a mean follow-up of 23 months. RESULTS: The primary outcome occurred in fewer patients in the rivaroxaban-plus-aspirin group than in the aspirin-alone group (379 patients [4.1%] vs. 496 patients [5.4%]; hazard ratio, 0.76; 95% confidence interval [CI], 0.66 to 0.86; P<0.001; z=−4.126), but major bleeding events occurred in more patients in the rivaroxaban-plus-aspirin group (288 patients [3.1%] vs. 170 patients [1.9%]; hazard ratio, 1.70; 95% CI, 1.40 to 2.05; P<0.001). There was no significant difference in intracranial or fatal bleeding between these two groups. There were 313 deaths (3.4%) in the rivaroxaban-plus-aspirin group as compared with 378 (4.1%) in the aspirin-alone group (hazard ratio, 0.82; 95% CI, 0.71 to 0.96; P=0.01; threshold P value for significance, 0.0025). The primary outcome did not occur in significantly fewer patients in the rivaroxaban-alone group than in the aspirin-alone group, but major bleeding events occurred in more patients in the rivaroxaban-alone group. CONCLUSIONS: Among patients with stable atherosclerotic vascular disease, those assigned to rivaroxaban (2.5 mg twice daily) plus aspirin had better cardiovascular outcomes and more major bleeding events than those assigned to aspirin alone. Rivaroxaban (5 mg twice daily) alone did not result in better cardiovascular outcomes than aspirin alone and resulted in more major bleeding events
Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part one
- Author
- A. Berman
- A. Cochino
- A. De Jesus
- A. Groll
- A. Insalaco
- A. Jansson
- A. Kazmirchyk
- A. Kozlova
- A. Lazar
- A. Martini
- A. Martini
- A. Martini
- A. Martini
- A. Martini
- A. Ombrello
- A. Pistorio
- A. Ravelli
- A. Simon
- A. Simon
- A. Simon
- A. Simon
- A. Speziale
- A. Speziale
- A. Speziale
- A. Speziale
- A. Speziale
- A. Zeft
- A. Zeft
- A. Zeft
- Abdullah Alsonbul
- Abdullah Calıskan
- Achille Marino
- Acute-JIA Study Group
- Adel Al-Wahadneh
- Adele Civino
- Adele D’Amico
- Adrian Liston
- Adriana Ivonne Cespedes-Cruz
- Adriana Rodriguez Vidal
- Adriana S. Díaz-Maldonado
- Agneza Marija Pasini
- Ahmet B. Cekgeloglu
- Ahmet Gul
- Aki Hanaya
- Akihiro Yachie
- Akihiro Yachie
- Akihiro Yachie
- Alain Fischer
- Alan Salama
- Alberto Garaventa
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Martini
- Alberto Tommasini
- Alberto Tommasini
- Alberto Tommasini
- Alberto Vieira
- Aleksandra Czajkowska
- Aleksandra Szabat
- Aleksandre Kajrishvili
- Aleksandre Kajrishvili
- Aleksey Kozhevnikov
- Alena Torbyak
- Alenka Gagro
- Alessandra Meneghel
- Alessandra Russo
- Alessandro Cafarotti
- Alessandro Consolaro
- Alessandro Consolaro
- Alessandro De Fanti
- Alessandro Ventura
- Alessia Omenetti
- Alessia Omenetti
- Alessia Omenetti
- Alexandre Belot
- Alexandre Belot
- Alexandre Belot
- Alexandre Belot
- Alexey Maschan
- Alfonso Ragnar Torres-Jimenez
- Alfred Mahr
- Alice Grossi
- Alice Grossi
- Alma Nunzia Olivieri
- Alma Olivieri
- Almira Ćosićkić
- Amanda Ombrello
- Amanda Radulescu
- Amanda Saracino
- Amit Rawat
- Amit Rawat
- Amit Rawat
- Amra Adrovic
- Amra Adrovic
- Amra Adrovic
- Amra Adrovic
- Amra Adrovic
- Amra Adrovic
- An Goris
- Ana F. Mourão
- Ana M. Marín Sánchez
- Ana V. Villarreal
- Ana V. Villarreal Treviño
- Ana V. Villarreal-Treviño
- Ana Vieira
- Ana Villarreal
- Anders Fasth
- Andrea Magnolato
- Andrea Pession
- Andrea Petretto
- Andrea Taddio
- Andrea Taddio
- Andrea Taddio
- Andressa G. Alves
- Andressa G. Alves
- Andrew Henrey
- Angel J. Flores-Pineda
- Angela Aquilani
- Angela C. Mosquera
- Angela C. Mosquera
- Angela Cox
- Angela Mauro
- Angela Mauro
- Angela Mauro
- Angela McArdle
- Angela Miniaci
- Angela Pistorio
- Angela Pistorio
- Angela Rösen-Wolff
- Angelika Thon
- Angelo Ravelli
- Angelo Ravelli
- Angelo Ravelli
- Angelo Ravelli
- Angelo Ravelli
- Angelo Ravelli
- Angelo Ravelli
- Angelo Ravelli
- Anita Dhanrajani
- Anju Gupta
- Anju Gupta
- Anju Gupta
- Anju Gupta
- Anju Gupta
- Ankur Kumar
- Ankur Kumar
- Anna C. Schulz
- Anna Gruenpeter
- Anna Kozlova
- Anna Mondino
- Anna Pogodina
- Anna Rubartelli
- Anna Shcherbina
- Anna Simon
- Anna Vermé
- Annacarin Horne
- Annalisa Chiocchetti
- Annalisa Salis
- Anne Grethe Jurik
- Anne H. Spannow
- Anne Hinks
- Anne Hulin
- Anne Lohse
- Anne Pagnier
- Anne Thorwarth
- Anne-Laure Mathieu
- Anneleen Avau
- Annemarie van Nieuwenhuijze
- Annemieke S. Littooij
- Annette Jansson
- Annette Keylock
- Annette von Scheven-Gête
- Antje Nimtz-Talaska
- Anton Hospach
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Insalaco
- Antonella Petaccia
- Antonella Petaccia
- Antonella Petaccia
- Antonia Kienast
- Antonio Fernández-Nebro
- Antonio L. Urda Cardona
- Antonio L. Urda Cardona
- Antonio Novelli
- Antonio Urda-Cardona
- Ariane Klein
- Ariane Standing
- Arinna Bertoni
- Arinna Bertoni
- Arinna Bertoni
- Arne Hørlyck
- Aygen Yılmaz
- Aysenur Pac Kısaarslan
- Aysenur Pac Kisaarslan
- Ayşen Bingöl
- Ayşenur Kısaarslan
- B. Flato
- B. Lauwerys
- B. Lauwerys
- Bahar Muezzinoglu
- Balahan Makay
- Balahan Makay
- Balahan Makay
- Banu Acar
- Banu Orak
- Barbara Stanimirovic
- Belinda Hernandez
- Belkisa Čolić
- Berenice Sanchez-Jara
- Berent Prakken
- Berent Prakken
- Beril Talim
- Berit Flato
- Berna E. Fidanci
- Berna Eren Fidanci
- Berta Lopez Montesinos
- Betul Sozeri
- Betul Sozeri
- Betul Sozeri
- Betül Sozeri
- Betül Sözeri
- Beverley Almeida
- Biagio Castaldi
- Bianca Lattanzi
- BIKER collaborative group
- Bilade Cherqaoui
- Biljana Djurdjevic-Banjac
- Biman Saikia
- Biman Saikia
- Birgitte T. Mahler
- Bita Arabshahi
- Bo Magnusson
- Bo Magnusson
- Board of the Swedish Pediatric Rheumatology Registry
- Bogumiła Szponar
- Boris Huegle
- Boris Hugle
- Brenden Dufault
- Brent Adler
- Brian M. Feldman
- Brigitte Bader-Meunier
- Brigitte Bader-Meunier
- Brigitte Bader-Meunier
- Brigitte Bader-Meunier
- Brigitte Bader-Meunier
- Bruno Charbit
- Bruno Dallapiccola
- Butsabong Lerkvaleekul
- Butsabong Lerkvaleekul
- Bénédicte Neven
- Bénédicte Neven
- C H. Spencer
- C. C. Barbosa Sandoval de Souza
- C. H. Spencer
- C. Wang
- C. Wouters
- Cagla Kaymakamgil
- Calin Lazar
- Calin Lazar
- Calin Lazar
- Camilla Celani
- Camilo Vargas
- CAPS
- Carine H. Wouters
- Carine Wouters
- Carine Wouters
- Carine Wouters
- Carla Aguilar Blancafort
- Carla Maldini
- Carlos Eduardo Ramalho
- Carolin Pretzer
- Carolina Uggenti
- Carolina Uggenti
- Caroline Freychet
- Caroline M. Andreasen
- Carsten W. Heuck
- Casper Schoemaker
- Caterina Di Battista
- Caterina Pellecchia
- Catherine Adamsbaum
- Catherine Orzechowski
- Cathryn E. Harkness
- Cecilia Lazea
- Chack-Yung Yu
- Chantal Deslandre
- Chantal Job Deslandre
- Charalampia Papadopoulou
- Charlotte Eijkelboom
- Chiara Lavarello
- Chiara Marini
- Chiara Passarelli
- Chiara Passarelli
- Chiara Trentin
- Chloe M. Stephenson
- Chris Pruunsild
- Chris Wallace
- Chris Williams
- Christelle Sordet
- Christiaan Scott
- Christian Høst
- Christian Pagnoux
- Christina Boros
- Christina Boros
- Christina Boros
- Christina Boros
- Christina Peterson
- Christine Arango
- Christine Barnerias
- Christine Bodemer
- Christine Bodemer
- Christine Bodemer
- Christine Bodemer
- Christine Nirschl
- Christine Seib
- Christine Soler
- Christoph Kessel
- Christoph Kessel
- Christopher Piper
- Chung-Yung Yu
- Ciaran Duffy
- Claas Hinze
- Claas Hinze
- Claas Hinze
- Claas Hinze
- Claire Grimwood
- Claire Hoyoux
- Claire Murphy
- Claire T. Deakin
- Clara Gimenez Roca
- Clara Giménez Roca
- Clara Malagon
- Clara Malagon
- Clara Malattia
- Clara Malattia
- Clara Malattia
- Clare Pain
- Clarissa Pilkington
- Clarissa pilkington
- Clarissa Pilkington
- Claudia Bracaglia
- Claudia Mauri
- Claudia Pastorino
- Claudia Pastorino
- Claudia Pastorino
- Claudia Poloni
- Claudio Lavarello
- Claudio Lavarello
- Clotilde Alizzi
- Clotilde Alizzi
- Consuelo Modesto
- Consuelo Modesto Caballero
- Consuelo Modesto Caballero
- Consuelo Modesto Caballero
- Cosimo Giannini
- Coskun F. Ozkececi
- Coskun F. Ozkececi
- Craig Kinnear
- Cristina Battagliotti
- Cristina Battagliotti
- Cristina Battagliotti
- Cristina de Min
- Cyril Gitiaux
- Cécile Gaujoux-Viala
- D. A. Williams
- D. Arikan
- D. J. Lovell
- D. J. Lovell
- D. Lovell
- D. Lovell
- D. Rigante
- Daiva Gorczyca
- Damien Bentayou
- Damien Noone
- Dan Cosma
- Dan Vasilescu
- Dan Ø. Pradsgaard
- Dana Nemcova
- Dana Nemcova
- Dana Nemcova
- Dana Nemcova
- Dana Němcová
- Daniel J. Lovell
- Daniel Kelberman
- Daniel L. Kastner
- Daniel L. Kastner
- Daniel Lovell
- Daniel Windschall
- Daniel Álvarez de la Sierra
- Daniela Chroustová
- Daria Augustyniak
- Darragh Duffy
- Darragh Duffy
- David Isenberg
- David Jayne
- David Moreno Romo
- Davide Gatti
- Deborah Stone
- Deepthi R. Abraham
- Deepti Suri
- Deepti Suri
- Delphine Regnard
- Demet Kartal
- Denise Ferrera
- Denise Lasigliè
- Denise Pires Marafon
- Denise Pires Marafon
- Denise Pires Marafon
- Denise Pires Marafon
- Denise Pires Marafon
- Denise Pires-Marafón
- Deniz Dogru
- Despina Eleftheriou
- Despina Eleftheriou
- Despina Eleftheriou
- Despina Eleftheriou
- Despina Eleftheriou
- Despina Eleftheriou
- Despina Eleftheriou
- Despina Moshous
- Despoina Maritsi
- Despoina Maritsi
- Diana Sueiro Delgado
- Diane Hebert
- Didier Bessis
- Diego R. Salinas-Encinas
- Diego Vozzi
- Dilek Konukbay
- Dilek Yıldız
- Dilek Yildiz
- Dilek Yılmaz
- Dirk Foell
- Dirk Foell
- Dirk Foell
- Dirk Foell
- Dirk Foell
- Dirk Foell
- Dirk Föll
- Dirk Föll
- Dirk Holzinger
- Dirk Holzinger
- Dirk Holzinger
- Dirk Holzinger
- Dita Cebecauerová
- Do Young Kim
- Dogan Simsek
- Dogan Simsek
- Dogan Simsek
- Dogan Simsek
- Domenico Biasi
- Donatella Vairo
- Donato Rigante
- Donato Rigante
- Donato Rigante
- Donato Rigante
- Dong Soo Kim
- Dorota Rowczenio
- Doğan Simsek
- Duarte Alves
- E. Alekseeva
- E. Alexeeva
- E. Ben-Chetrit
- E. Ben-Chetrit
- E. Ben-Chetrit
- E. Castagnola
- E. Demirkaya
- E. Hachulla
- E. Haddad
- E. Nasonov
- E. Papadopoulou-Alataki
- E. Solau-Gervais
- E. Tsitami
- E. Vritzali
- Ebru Yalcin
- Ebru Yilmaz
- Ebun Omoyinmi
- Edel R. Rodea-Montero
- Edi Paleka Bosak
- Edita Kabíčková
- Edyta Olesińska
- EH Pieter Van Dijkhuizen
- Eileen Baildem
- Eileen Hoal
- Ekaterina Alexeeva
- Ekaterina Alexeeva
- Ekaterina Alexeeva
- Ekaterina Kulesh
- Elaine F. Remmers
- Elaine F. Remmers
- Elena Raikina
- Elena Reffo
- Eleonora Fanti
- Elif Comak
- Elisa Fazzi
- Elisa Patrone
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- Working Group of Behçet’s Disease Pediatric Rheumatology Association of Japan (PRAJ)
- Working Group “Juvenile Dermatomyositis” of the German Society for Paediatric and Adolescent Rheumatology (GKJR)
- Working Group “Juvenile Dermatomyositis” of the German Society for Paediatric and Adolescent Rheumatology (GKJR)
- X. Li
- X. Wei
- X. Xu
- Xiaomin Yu
- Y. Joubert
- Y. Joubert
- Y. Joubert
- Y. Joubert
- Y. Uziel
- Yanick Crow
- Yanick Crow
- Yanick Crow
- Yanick Crow
- Yanick J. Crow
- Yasar Karaaslan
- Yasin Bulut
- Yasuo Nakagishi
- Yasushi Kawaguchi
- Yavuz Tokgöz
- Yelda Bilginer
- Yelda Bilginer
- Yelda Bilginer
- Yelda Bilginer
- Yelda Bilginer
- Yiannis Ioannou
- Yiannis Ioannou
- Ying Hong
- Ying Hong
- Yoann Rose
- Yoann Rose
- Yonatan Butbul
- Yosef Uziel
- Yosef Uziel
- Yosef Uziel
- Yosef Uziel
- Yosuke Fujii
- Yukie Saito
- Yuksel Aliyazicioglu
- Yulia Kostina
- Yulia Kostina
- Yumi Tani
- Yunus Arıkan
- Yuridiana Ramirez
- Yuridiana Ramirez Loyola
- Yuridiana Ramírez
- Yvonne Kusche
- Z. Serap Arıcı
- Zehra Serap Arici
- Zelal Ekinci
- Zelal Ekinci
- Zelal Ekinci
- Zelal Ekinci Ekinci
- Zeno Sparchez
- Zeyad El-Habahbeh
- Zeynep Birsin Özçakar
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- Zubeyde Gunduz
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- Şebnem Sara Kılıc
- Publication venue
- place:236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
- Publication date
- 01/01/2017
- Field of study
A Survey of Empirical Results on Program Slicing
- Author
- ABAT MARC EVANS
- ABDUL RAHIM AIZAI AZAN
- ABE MITSUNORI
- ABIB JR EDUARDO
- ABOLA MARIA TERESA
- Aboyans Victor
- ABOYANS VICTOR
- ABRANTES JOSE ANTONIO
- ABU HASSAN MUHAMMAD RADZI
- ACCINI MENDOZA JOSE LUIS
- ADLER FREDRIC
- AHUAD GUERRERO RODOLFO ANDRES
- AKATSUKA YUTAKA
- AKO JUNYA
- AL-KHALILI FARIS
- AL-QOOFI FAISAL
- ALBERTSSON PER
- ALBISU DI GENNERO JUAN PABLO
- ALCARAZ JOHN DENNIS
- Alings Marco
- ALINGS MARCO
- ALMROTH HENRIK
- ALVAREZ MOIRA
- AMERENA JOHN
- Anand Sonia S
- ANDERSSON TOMMY
- ANDO KENJI
- ANONUEVO JOHN
- APPEL KARL-FRIEDRICH
- ARCOS EDGAR
- ARIMIE RALUCA
- AROCA GUSTAVO
- ARSENESCU CATALINA
- ATAR SHAUL
- AUSHEVA AZA
- AUSTIN DAVID
- AVERKOV OLEG
- Avezum Alvaro A
- BABAPULLE MOHAN
- BACHARACH J MICHAEL
- BAE JANG-HO
- BAI XIAO JUAN
- BAINEY KEVIN
- BAJNOK LASZLO
- BAKAEEN FAISAL
- BAKAI JUDIT
- BALDIN MARIA GRAZIA
- BANERJEE SUBHASH
- Bangdiwala Shrikant I
- BARBARASH OLGA
- BARBIERI MARIA
- BARTELS GERARD
- BARTOLACCI INES PALMIRA
- BARTON JOHN
- BAZYLEVYCH ANDRIY
- BEDWELL NOEL
- BENEDEK IMRE
- BENESOVA MIROSLAVA
- BERLINGIERI JOSEPH
- BERNARDINANGELI MARINO
- BHARGAVA RAKESH
- Bhatt Deepak L
- BIRDI INDERPAUL
- BITTNER VERA
- BLACK ROBERT
- BLOMBERY PETER
- BOBESCU ELENA
- BOCCARA FRANCK
- BODA ZOLTAN
- BOENELYKKE SOERENSEN VIBEKE
- BORDONAVA ANSELMO PAULINO
- Bosch Jackie
- BOSI STEFANO
- BOTELHO ROBERTO
- BOURGEOIS RONALD
- BOYLE ANDREW
- BRAILE MARIA
- Branch Kelley
- BRANCH KELLEY
- BRANNY MARIAN
- BRAT RADIM
- BRAUN-DULLAEUS RUEDIGER
- BREEDVELD ROB
- BRONCEL MARLENA
- BROWN CRAIG
- BRTKO MIROSLAV
- BRULOTTE STEEVE
- CACCAVO ALBERTO
- CALVERT JOHN
- CAMP ALAN
- CAMPEAU JEAN
- CANADYOVA JULIA
- CARDONA MARCELO
- CARMINE DE MATTEIS
- CARROLL PATRICK
- CARTASEGNA LUIS
- CARTER JUSTIN
- CASTILLO HENRY
- CAYLA GUILLAUME
- CHA JAMES
- CHACON CAROLINA
- CHANDRA LOKESH
- Chen Edmond
- CHEN XIAO PING
- CHEN XIN
- CHILTON ROBERT
- CHIONCEL OVIDIU
- CHUA PHILIP
- CINTEZA MIRCEA
- CIRRINCIONE VINCENZO
- COBOS JORGE LEONARDO
- COLQUHOUN DAVID
- COMAN IOAN
- COMEROTA ANTHONY
- COMMERFORD PATRICK
- Commerford Patrick J
- CONNOLLY DEREK
- Connolly Stuart J
- CORBALAN RAMON
- COSMI FRANCO
- COSTABEL JUAN PABLO
- COSTELLO FREDERICK
- COTTON JAMES
- COUFAL ZDENEK
- CREAN PETER
- CRUZ JOSEFINA
- CUADRADO JESUS
- CUERVO MILLAN FRANCISCO
- CUNEO CARLOS
- CURTIN RONAN
- CZARNECKA DANUTA
- CZARNECKI WLODZIMIERZ
- DAGENAIS FRANCOIS
- DAGENAIS GILLES R
- DAGHER GEORGE
- DAIDA HIROYUKI
- DARIUS HARALD
- DAVEY PATRICK
- DAVIERWALA PIROZE
- DE CARVALHO CANTARELLI MARCELO JOSE
- DE GROOT MARC ROBERT
- DE VRIES KEES-JAN
- DEBONNAIRE PHILIPPE
- DEL PILAR JOSE CARLO
- DELLA SIEGA ANTHONY
- DELLBORG MIKAEL
- DEMPSEY STEPHEN
- DEN HARTOG FRANK
- DI BIASE MATTEO
- DI PASQUALE GIUSEPPE
- DIAZ ARIEL
- Diaz Rafael
- DIMULESCU DOINA
- DINNEEN SEAN
- DIXEN ULRIK
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- DOMAE HIROSHI
- DONG YUGANG
- DONNELLY PATRICK
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- DROZDAKOVA ERIKA
- DUARTE YAN CARLOS
- DUENGEN HANS-DIRK
- DUJARDIN KARL
- DUTRA OSCAR
- EBO GERALDINE
- ECTOR BAVO
- EFREMUSHKINA ANNA
- Eikelboom John W
- ELEGEERT IVAN
- ENGELBRECHT JAN
- FAGGIANO POMPILIO
- FELL DAVID
- FERRARI EMILE
- FERRE PACORA FREDY ANTONI
- FIELDS RONALD
- FLORIAN JINDRICH
- FOLTYNOVA CAISOVA LENKA
- Fox Keith A A
- FREMES STEPHEN
- FRENCH WILLIAM
- FU GUOSHENG
- FUJII KENSHI
- GAITA DAN
- GAJOS GRZEGORZ
- GALVANI MARCELLO
- GARCIA DURAN RUBEN OMAR
- GARCIA HENRY
- GARCIA LUIS HERNANDO
- GARRIDO MARCELO
- GASPAR LUDOVIT
- GE JUNBO
- GIBSON KATHLEEN
- GILLESPIE EVE
- GISLASON GUNNAR
- GLANZ ANTHONY
- GOGIA HARINDER
- GOMEZ VILAMAJO OSCAR
- GOMEZ JUAN
- GONZALEZ COLASO PATRICIA DEL CARMEN
- GOSSELIN GILBERT
- GOSSELINK MARCEL
- GRENA PAUL
- GRINFELD DIEGO
- GROENEMEIJER BJORN
- GUEROCAK OSMAN
- GULIZIA MICHELE MASSIMO
- GURBEL PAUL
- GUZIK TOMASZ
- GUZMAN LUIS
- GUZMAN RANDOLPH
- HA JONG-WON
- HAKAS JOSEPH
- HALABI MAJDI
- HAMMETT CHRISTOPHER
- HAMROFF GLENN
- HARRISON ROBERT
- Hart Robert G
- HARTLEIB MICHAEL
- HASBANI EDUARDO
- HASHIMOTO TETSUO
- HATALOVA KATARINA
- HEFFERNAN MICHAEL
- HEIMAN MARK
- HERNANDES MAURO
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- HOSOKAWA SHINOBU
- HOULIND KIM
- HRABAR ADRIAN
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- HU TAO HONG
- HUANG WEIJIAN
- HUNTER JOHN J.
- HUYNH THAO
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- KIM YONG JIN
- KIM YOUNG-KWON
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- KINOSHITA NORIYUKI
- KIS ERNO
- KLAINMAN ELIEZER
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- KOBAYASHI HIROO
- KOBER LARS
- KONG YE
- KONONENKO LYUDMYLA
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- KORETSUNE YUKIHIRO
- KOSHY N. MATHEW
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- KOVAL OLENA
- KOVAL VALENTYNA
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- KRYZA RADIM
- KUKREJA NEVILLE
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- LAM ANDY
- LAMY ANDRE
- LASZLO ZOLTAN
- LEAES PAULO
- LECLERCQ FLORENCE
- Leong Darryl P
- LEROY JEAN
- LEWIS BASIL
- Lewis Basil S
- LI CHUNJIAN
- LI JIANPING
- LI JUNXIA
- LIGHEZAN DANIEL
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- Maggioni Aldo P
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- PITARGUE ARTHUR
- Pogosova Nana
- POLASEK ROSTISLAV
- POOR FERENC
- POPONINA TATIANA
- PORTNAY EDWARD
- POTTHOFF SERGIO
- POULTER ROHAN
- POW CHON LONG FREDDY
- POZDNYAKOV YURY
- PRECOMA DALTON
- PRETORIUS CATHARINA ELIZABETH
- PRINS F.J.
- PROKHOROV OLEKSANDR
- RAFFO CARLOS
- RANFT JURGEN
- RASMANIS GUNDARS
- RECH RAFAEL
- REFSGAARD JENS
- REIS GILMAR
- REPIN ALEXEY
- REY NANNETTE
- RHEAULT PAUL
- RICCI JOSEPH A
- RICHTER MAREK
- ROBBA DEBORA
- ROBERTS-THOMSON PHILIP
- ROGELIO GREGORIO
- ROGERS JAMES
- RONNER EELKO
- ROSSI DOS SANTOS FABIO
- ROSSI PAULO
- ROY ANNIE
- ROYSE ALISTAIR
- RUDENKO LEONID
- RUPKA DENNIS
- Ryden Lars
- RYNKIEWICZ ANDRZEJ
- SAKAMOTO TOMOHIRO
- SAKU KEIJIRO
- SALA JORGELINA
- SALACATA ABRAHAM
- SANCHEZ VALLEJO GREGORIO
- SANCHEZ MAYRA
- SANGRIGOLI RENEE
- SARAIVA JOSE
- SARJANOVICH RODOLFO JUAN
- SAUNDERS KEVIN
- SCHELLONG SEBASTIAN
- SCHIAVI LILIA BEATRIZ
- SCHNEIDER RICKY
- SCHROE HERMAN
- SCHYGIEL PABLO OMAR
- SEEDAT SAADIYA
- SEIWERT ANDREW
- SELVANAYAGAM JOSEPH
- SENIOR ROXY
- SEPULVEDA PABLO
- SEROTA HARVEY
- SERRANO JUNIOR CARLOS VICENTE
- SEVESTRE MARIE ANTOINETTE
- SHAMMAS NICOLAS
- SHAW JAMES
- SHIMOMURA HIDEKI
- SHUKLA DINKAR
- SHUKLE PRAVIN
- SINAGRA GIANFRANCO
- SINESCU CRINA
- SINGH BHUWAN
- SIZOVA ZHANNA
- SKALNIKOVA VLADIMIRA
- SLABY JOSEF
- SLOAN STEPHEN
- SOEGAARD PETER
- SONI ANAND
- SOTOMAYOR ARISTIDES
- SOUZA WEIMAR
- SPINAR JINDRICH
- SPINAROVA LENKA
- SRIVASTAVA SUNNY
- STEG GABRIEL
- STELLBRINK CHRISTOPH
- STOCKINS BENJAMIN
- STOERK STEFAN
- STOROZHUK BORYS
- STRAKA ZBYNEK
- STRAZHESKO IRINA
- Störk Stefan
- SULIT DENNIS JOSE
- SURESH DAMODHAR
- SWART HENK
- SZUBA ANDRZEJ
- TAKAHASHI AKIHIKO
- TANAJURA LUIZ FERNANDO
- TAO LIANG
- TENGMARK BENGT-OLOV
- TEODORESCU IULIA
- TERAN PABLO
- TESAK MARTIN
- TESLOIANU DAN
- THEW STEPHEN
- TIAN HONGYAN
- TIRADOR LOUIE
- TORSTENSSON INGEMAR
- TRETINA MARTIN
- TREVELYAN JASPER
- TRUJILLO DADA FREDY ALBERTO
- TRUJILLO FREDDY
- TSELUYKO VIRA
- TUOMILEHTO HENRI
- TUOMILEHTO HENRI
- TUOMILEHTO JAAKKO
- TUOMINEN MARJA-LEENA
- TURGEMAN YOAV
- TYTUS RICHARD
- UENO HIDEKI
- URINA MIGUEL
- UTSU NORIAKI
- VACANTE MICHAEL
- VAN BERGEN PAUL
- VAN DE BORNE PHILIPPE
- VAN DEN HEUVEL PAUL
- VAN DER BORGH ROGER
- VAN DER ZWAAN COEN
- VAN ECK JACOB
- VAN GORSELEN EDWIN
- VAN ZYL LOUIS
- Vanassche Thomas
- Varigos John D
- VASYUK YURY
- VDOVYCHENKO VALERIY
- VEJAR MARGARITA
- VENKATARAMAN ASOK
- VENSENTINI NATALIA
- VENTURI FLAVIO
- VERESS GABOR
- VERHAMME PETER
- VERTES ANDRAS
- VERTKIN ARKADIY
- VESGA BORIS
- VICO MARISA
- VIERGEVER ERIC
- Vinereanu Dragos
- VINEREANU DRAGOS
- VINTILA MARIUS MARCIAN
- VITA NESTOR ALEJANDRO
- VIZEL SAUL
- VIZIR VADYM
- VOEHRINGER HANS-FRIEDRICH
- VOEVODA MIKHAIL
- VOGEL DANIEL
- VOJTISEK PETR
- VOLKOV VOLODYMYR
- VORPAHL MARC
- VRANCKX PASCAL
- WAHLGREN CARL-MAGNUS
- WALSH RONALD
- WAN AHMAD WAN AZMAN
- WANG CHUNSHENG
- WANG ZHAOHUI
- WHELAN ALAN
- Widimsky Peter
- WIENDL MARTIN
- WIGGERS HENRIK
- WILLEMS FRANK
- WINKELMANN BERNHARD
- WU SHULIN
- WU XUESI
- WU ZONGQUI
- YAMADA TAKAHISA
- YAMADA YUTAKA
- YANG PING
- YANG YUN MEI
- YIN PENGFEI
- YOSHIDA TETSURO
- YU LITIAN
- YUSOFF KHALID
- Yusuf Salim
- ZABOWKA MACIEJ
- ZAIDMAN CESAR
- ZATEYSHCHIKOV DMITRY
- ZEGERS ERWIN
- ZELTSER DAVID
- ZEUTHEN ELISABETH
- ZHANG JIWEI
- ZHANG RUIYAN
- ZHENG YANG
- ZHENG ZHE
- ZHOU XINMIN
- Zhu Jun
- ZIDKOVA EVA
- ZIMLICHMAN REUVEN
- ZIMLICHMAN REUVEN
- ZIMMERMANN SERGIO LUIZ
- ZOET-NUGTEREN STIENEKE
- ZSARY ANDRAS
- Publication venue
- Publication date
- 01/01/2004
- Field of study
International audienceBACKGROUND:Patients with peripheral artery disease have an increased risk of cardiovascular morbidity and mortality. Antiplatelet agents are widely used to reduce these complications.METHODS:This was a multicentre, double-blind, randomised placebo-controlled trial for which patients were recruited at 602 hospitals, clinics, or community practices from 33 countries across six continents. Eligible patients had a history of peripheral artery disease of the lower extremities (previous peripheral bypass surgery or angioplasty, limb or foot amputation, intermittent claudication with objective evidence of peripheral artery disease), of the carotid arteries (previous carotid artery revascularisation or asymptomatic carotid artery stenosis of at least 50%), or coronary artery disease with an ankle-brachial index of less than 0·90. After a 30-day run-in period, patients were randomly assigned (1:1:1) to receive oral rivaroxaban (2·5 mg twice a day) plus aspirin (100 mg once a day), rivaroxaban twice a day (5 mg with aspirin placebo once a day), or to aspirin once a day (100 mg and rivaroxaban placebo twice a day). Randomisation was computer generated. Each treatment group was double dummy, and the patient, investigators, and central study staff were masked to treatment allocation. The primary outcome was cardiovascular death, myocardial infarction or stroke; the primary peripheral artery disease outcome was major adverse limb events including major amputation. This trial is registered with ClinicalTrials.gov, number NCT01776424, and is closed to new participants.FINDINGS:Between March 12, 2013, and May 10, 2016, we enrolled 7470 patients with peripheral artery disease from 558 centres. The combination of rivaroxaban plus aspirin compared with aspirin alone reduced the composite endpoint of cardiovascular death, myocardial infarction, or stroke (126 [5%] of 2492 vs 174 [7%] of 2504; hazard ratio [HR] 0·72, 95% CI 0·57-0·90, p=0·0047), and major adverse limb events including major amputation (32 [1%] vs 60 [2%]; HR 0·54 95% CI 0·35-0·82, p=0·0037). Rivaroxaban 5 mg twice a day compared with aspirin alone did not significantly reduce the composite endpoint (149 [6%] of 2474 vs 174 [7%] of 2504; HR 0·86, 95% CI 0·69-1·08, p=0·19), but reduced major adverse limb events including major amputation (40 [2%] vs 60 [2%]; HR 0·67, 95% CI 0·45-1·00, p=0·05). The median duration of treatment was 21 months. The use of the rivaroxaban plus aspirin combination increased major bleeding compared with the aspirin alone group (77 [3%] of 2492 vs 48 [2%] of 2504; HR 1·61, 95% CI 1·12-2·31, p=0·0089), which was mainly gastrointestinal. Similarly, major bleeding occurred in 79 (3%) of 2474 patients with rivaroxaban 5 mg, and in 48 (2%) of 2504 in the aspirin alone group (HR 1·68, 95% CI 1·17-2·40; p=0·0043).INTERPRETATION:Low-dose rivaroxaban taken twice a day plus aspirin once a day reduced major adverse cardiovascular and limb events when compared with aspirin alone. Although major bleeding was increased, fatal or critical organ bleeding was not. This combination therapy represents an important advance in the management of patients with peripheral artery disease. Rivaroxaban alone did not significantly reduce major adverse cardiovascular events compared with asprin alone, but reduced major adverse limb events and increased major bleeding