Predictable and robust performance of a Bi-2223 superconducting coil for compact isochronous cyclotrons

The development of ever smaller medical particle accelerators is motivated by a desire to make proton therapy accessible to more patients. Reducing the footprint of particle accelerators and subsequently proton therapy facilities allows for cheaper and broader usage of proton therapy. By employing superconducting technologies for field shaping, the size of particle accelerators can be reduced further below what is possible with saturated iron. This article discusses experiments on a first-of-its-kind double pancake (DP), and an assembly of six DP coils, designed to be used as a so-called ‘flutter coil’ for a compact isochronous cyclotron for proton therapy, fabricated from high-temperature superconducting (HTS) Bi 2 − x Pbx Sr2Ca2Cu3Oy (Bi-2223) tape. The coils were mounted under pre-stress within a stainless-steel structure to maintain mechanical stability during the experiments. The critical current as a function of the temperature of both coils was measured in a conduction-cooled setup. A model describing the coils, based on tape data, was created and revealed that the measurements were in excellent agreement with the predictions. Additional experiments were performed to study the quench and thermal runaway behaviour of the HTS coils, determining whether such coils can be protected against fault scenarios, using realistic quench-detection levels and discharge extraction-rates. These experiments demonstrate that the coils are very robust and can be well protected against quenches and thermal-runaway events using common quench-protection measures with realistic parameters.</p

A general scaling relation for the critical current density in Nb3Sn

We review the scaling relations for the critical current density (Jc) in Nb3Sn wires and include recent findings on the variation of the upper critical field (Hc2) with temperature (T) and A15 composition. We highlight deficiencies in the Summers/Ekin relations, which are not able to account for the correct Jc(T) dependence. Available Jc(H) results indicate that the magnetic field dependence for all wires can be described with Kramer's flux shear model, if non-linearities in Kramer plots are attributed to A15 inhomogeneities. The strain (eps) dependence is introduced through a temperature and strain dependent Hc2*(T,eps) and Ginzburg- Landau parameter kappa1(T,eps) and a strain dependent critical temperature Tc(eps). This is more consistent than the usual Ekin unification, which uses two separate and different dependencies on Hc2*(T) and Hc2*(eps). Using a correct temperature dependence and accounting for the A15 inhomogeneities leads to a remarkable simple relation for Jc(H,T,eps). Finally, a new relation for s(eps) is proposed, based on the first, second and third strain invariants.Comment: Accepted Topical Review for Superconductor, Science and Technolog

Optimisation of ITER Nb3Sn CICCs for coupling loss, transverse electromagnetic load and axial thermal contraction

The ITER cable-in-conduit conductors (CICCs) are built up from sub-cable bundles, wound in different stages, which are twisted to counter coupling loss caused by time-changing external magnet fields. The selection of the twist pitch lengths has major implications for the performance of the cable in the case of strain sensitive superconductors, i.e. Nb3Sn, as the electromagnetic and thermal contraction loads are large but also for the heat load from the AC coupling loss. Reduction of the transverse load and warm-up cool-down degradation can be reached by applying longer twist pitches in a particular sequence for the sub-stages, offering a large cable transverse stiffness, adequate axial flexibility and maximum allowed lateral strand support. Analysis of short sample (TF conductor) data reveals that increasing the twist pitch can lead to a gain of the effective axial compressive strain of more than 0.3 % with practically no degradation from bending. For reduction of the coupling loss, specific choices of the cabling twist sequence are needed with the aim to minimize the area of linked strands and bundles that are coupled and form loops with the applied changing magnetic field, instead of simply avoiding longer pitches. In addition we recommend increasing the wrap coverage of the CS conductor from 50 % to at least 70 %. The models predict significant improvement against strain sensitivity and substantial decrease of the AC coupling loss in Nb3Sn CICCs, but also for NbTi CICCs minimization of the coupling loss can be achieved. Although the success of long pitches to transverse load degradation was already demonstrated, the prediction of the combination with low coupling loss needs to be validated by a short sample test.Comment: to be published in Supercond Sci Techno

Maturation of monocyte-derived dendritic cells with Toll-like receptor 3 and 7/8 ligands combined with prostaglandin E2 results in high interleukin-12 production and cell migration

Dendritic cells (DC) are professional antigen-presenting cells of the immune system that play a key role in regulating T cell-based immunity. In vivo, the capacity of DC to activate T cells depends on their ability to migrate to the T cell areas of lymph nodes as well as on their maturation state. Depending on their cytokine-secreting profile, DC are able to skew the immune response in a specific direction. In particular, IL-12p70 producing DC drive T cells towards a T helper 1 type response. A serious disadvantage of current clinical grade ex vivo generated monocyte-derived DC is the poor IL-12p70 production. We have investigated the effects of Toll-like receptor (TLR)-mediated maturation on ex vivo generated human monocyte-derived DC. We demonstrate that in contrast to cytokine-matured DC, DC matured with poly(I:C) (TLR3 ligand) and/or R848 (TLR7/8 ligand) are able to produce vast amounts of IL-12p70, but exhibit a reduced migratory capacity. The addition of prostaglandin E2 (PGE2) improved the migratory capacity of TLR-ligand matured DC while maintaining their IL-12p70 production upon T cell encounter. We propose a novel clinical grade maturation protocol in which TLR ligands poly(I:C) and R848 are combined with PGE2 to generate DC with both high migratory capacity and IL-12p70 production upon T cell encounter

Thermal and electrical design of superconducting demonstrator for magnetic density separation

In this paper the focus is on thermal and electrical design aspects of a NbTi-based demonstrator magnet for magnetic density separation (MDS) that is being constructed at the University of Twente. MDS is a recycling technology that allows the separation of non-magnetic particles based on their mass density, using a vertical magnetic field gradient and a ferrofluid. To minimize the distance between the planar array of racetrack coils and the ferrofluid bath, the system is conduction-cooled. First the thermal design is presented, which shows that the coils can operate below 4.5 K with sufficient margin using a single cryocooler. High-purity aluminium heat drains enable a low thermal gradient across the cold mass. The current path is introduced, as well as the adopted protection scheme. The magnet's stored energy can safely be dumped in the coils. Diodes are placed (anti-)parallel to the coils in the cold to prevent high terminal voltages. In the case of a quench in the superconducting part of the current leads or an external anomaly, a switch is opened and the current is forced through a resistor in series with the diodes, causing a deliberate transition of the coils to the normal state and thus a fast ramp-down

SELFIE: ITER superconducting joint test facility

In the frame of a contract with ITER Organization (IO) on magnets assembly support, CEA designed and built a superconducting joint test facility called SELFIE (ITER SELf-FIEld joint test facility). This facility is installed at CEA Cadarache and started to operate in 2022. This project was initiated by IO for quality control of critical assembly activities. Indeed, the magnet superconducting joints assembly is a special process, for which the performance cannot be verified until the full Tokamak is at cryogenic temperature and obviously repair cannot be envisaged once the machine is assembled. Therefore, the quality control of these joints assembly relies on procedures and qualification of the workers in charge of their implementation. As the joints assemblies will span over three years of the ITER construction, the qualified workers will have to assemble periodically some Production Proof Samples (PPS) joints to train and keep their certification valid. The purpose of SELFIE is to test these PPS in a timely manner. The tests scope is the measurement of the PPS resistance (few nOhms). For that purpose, PPS integrated in ITER conductors length (∼200 kg weight and 3600 mm length) are tested in a liquid helium bath (4.2 K), at nominal current (up to 70 kA), in self-field. The current is provided by a superconducting transformer integrated in the same cryostat as the sample. CEA finalized the preliminary design in 2019, complying with the requirement to achieve a full test sequence within one week (controlled cool down, test and warm-up), with an optimised operation cost. The detailed design phase was started in April 2020 followed by the manufacturing phase up to mid 2021. SELFIE integration and installation were achieved in December 2021 and the cold commissioning done in January 2022. This paper presents the SELFIE test facility and the first results

Measurement and Numerical Evaluation of AC Losses in a ReBCO Roebel Cable at 4.5 K

EuCARD-2 aims to research ReBCO superconducting magnets for future accelerator applications. The properties of ReBCO conductors are very different from low-temperature superconductors. To investigate dynamic field quality, stability, and normal zone propagation, an electrical network model for coated conductor cables was developed. To validate the model, two identical samples were prepared at CERN, after which measurements were taken at the University of Twente and Southampton University. The model predicts that for a Roebel cable, in a changing magnetic field applied in the perpendicular direction, hysteresis loss is much larger than coupling loss. In the case of a changing magnetic field applied parallel to the cable, coupling loss is dominant. In the first case, the experiment is in good agreement with the model. In the second case, the data can only be compared qualitatively because the calibration for the inductive measurement is not available