A Study on Keel Vayu

Siddha system of medicine is a most primitive, ancient system of medicine. which deals with the diseases of humanbeings efficiently with the knowledge of both subtle and also the gross material body Siddha means achievement or erfection.siddha system is largely therapeutic in nature and its origin can be traced back to birth of human race on the planet the clinical study on keel vaayu with reference to its aetiology, pathogenesis,he clinical study on keel vaayu with reference to its aetiology, pathogenesis, investigations, clinical features, diagnosis and treatment

Ontology based Comprehensive Architecture for Service Discovery in Emergency Cloud

Abstract — Disasters such as Tsunami, Landslides, and cyclones occur frequently and a strong emergency management system is required to manage such situations. These kinds of crisis circumstances are expected to increase in future. The role of Information and communication technology can largely aid in handling calamities and provide first aid support. The characteristics of Cloud computing such as sharing on demand, connecting communities and offering everything as a service clearly indicate that it can contribute to crisis without affecting business continuity. Hence efforts have taken to articulate web services and the cloud infrastructure as ontology, in the perspective of emergency management which can improve the understanding of this proposed agent based comprehensive architecture

Study of antidiarrheal activity of Hydrocotyle javanica in mice

The effect of the methanolic leaf extract of Hydrocotyle javanica (family Hydrocharitaceae) was investigated in mice to evaluate its antidiarrheal activity on magnesium sulfate (MgSO4) induced diarrhea and gastrointestinal motility. Hydrocotyle javanica, at doses of 50 mg/kg and 100 mg/kg, was tested for its effect on fecal output in magnesium sulfate induced diarrhea in albino mice and the results (percentage of animals showing diarrhea) were compared with those of diphenoxylate hydrochloride, a standard allopathic antidiarrheal drug. Hydrocotyle javanica (at a dose of 100 mg/kg) inhibited the magnesium sulfate induced diarrhea and also reduced gastrointestinal motility in mice. The results indicate that the leaf extract significantly reduced diarrhea in mice with a reduction in weight of stools. Keywords: Hydrocotyle javanica, antidiarrheal, magnesium sulphate, diphenoxylate hydrochloride, gastrointestinal motility, methanolic leaf extract The East and Central African Journal of Pharmaceutical Sciences Vol. 8(2) 2005: 31-3

Antagonistic Property of Selected Herbal Combination for Substitute of Synthetic Antimicrobial Agents

The emergence and spread of bacterial strains of multi- drug resistant continues to challenge the healthcare sector of both developed and developing countries. Owing to this problem and concerning the side effects of synthetic antimicrobial agents, the current work was done with medicinal plants. The plant materials such as Terminalia bellerica, Withania somnifera, Madhuca longifolia and Sygyzium cumini was selected based on its potent antimicrobial activity. The best combination of the selected plants was evaluated for their antimicrobial activity. The phytochemical analysis of the selected combination showed the presence of phytoconstituents that are responsible for their biocidal activity. The Minimum inhibitory concentration (MIC) was studied for the selected herbal combination. The results recommend the use of selected plants at their best combination as a substitute to synthetic agents that can effectively prevent the microbial infestation. Keywords: Antimicrobial activity, Cross infection, Medicinal Plant, MIC, Phytochemical

SINGLE VERSUS MULTIPLE TRIAL VECTORS IN CLASSICAL DIFFERENTIAL EVOLUTION FOR OPTIMIZING THE QUANTIZATION TABLE IN JPEG BASELINE ALGORITHM

Quantization Table is responsible for compression / quality trade-off in baseline Joint Photographic Experts Group (JPEG) algorithm and therefore it is viewed as an optimization problem. In the literature, it has been found that Classical Differential Evolution (CDE) is a promising algorithm to generate the optimal quantization table. However, the searching capability of CDE could be limited due to generation of single trial vector in an iteration which in turn reduces the convergence speed. This paper studies the performance of CDE by employing multiple trial vectors in a single iteration. An extensive performance analysis has been made between CDE and CDE with multiple trial vectors in terms of Optimization process, accuracy, convergence speed and reliability. The analysis report reveals that CDE with multiple trial vectors improves the convergence speed of CDE and the same is confirmed using a statistical hypothesis test (t-test)

A specification-based QoS-aware design framework for service-based applications

Effective and accurate service discovery and composition rely on complete specifications of service behaviour, containing inputs and preconditions that are required before service execution, outputs, effects and ramifications of a successful execution and explanations for unsuccessful executions. The previously defined Web Service Specification Language (WSSL) relies on the fluent calculus formalism to produce such rich specifications for atomic and composite services. In this work, we propose further extensions that focus on the specification of QoS profiles, as well as partially observable service states. Additionally, a design framework for service-based applications is implemented based on WSSL, advancing state of the art by being the first service framework to simultaneously provide several desirable capabilities, such as supporting ramifications and partial observability, as well as non-determinism in composition schemas using heuristic encodings; providing explanations for unexpected behaviour; and QoS-awareness through goal-based techniques. These capabilities are illustrated through a comparative evaluation against prominent state-of-the-art approaches based on a typical SBA design scenario

Albiglutide, a Long Lasting Glucagon-Like Peptide-1 Analog, Protects the Rat Heart against Ischemia/Reperfusion Injury: Evidence for Improving Cardiac Metabolic Efficiency

BACKGROUND: The cardioprotective effects of glucagon-like peptide-1 (GLP-1) and analogs have been previously reported. We tested the hypothesis that albiglutide, a novel long half-life analog of GLP-1, may protect the heart against I/R injury by increasing carbohydrate utilization and improving cardiac energetic efficiency. METHODS/PRINCIPAL FINDINGS: Sprague-Dawley rats were treated with albiglutide and subjected to 30 min myocardial ischemia followed by 24 h reperfusion. Left ventricle infarct size, hemodynamics, function and energetics were determined. In addition, cardiac glucose disposal, carbohydrate metabolism and metabolic gene expression were assessed. Albiglutide significantly reduced infarct size and concomitantly improved post-ischemic hemodynamics, cardiac function and energetic parameters. Albiglutide markedly increased both in vivo and ex vivo cardiac glucose uptake while reducing lactate efflux. Analysis of metabolic substrate utilization directly in the heart showed that albiglutide increased the relative carbohydrate versus fat oxidation which in part was due to an increase in both glucose and lactate oxidation. Metabolic gene expression analysis indicated upregulation of key glucose metabolism genes in the non-ischemic myocardium by albiglutide. CONCLUSION/SIGNIFICANCE: Albiglutide reduced myocardial infarct size and improved cardiac function and energetics following myocardial I/R injury. The observed benefits were associated with enhanced myocardial glucose uptake and a shift toward a more energetically favorable substrate metabolism by increasing both glucose and lactate oxidation. These findings suggest that albiglutide may have direct therapeutic potential for improving cardiac energetics and function