17,251 research outputs found

    Observations on Cost of Medical Education

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    The Use of Magnetic Iron Oxide for Recovery of Virus from Water

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    Summary of tower designs for large horizontal axis wind turbines

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    Towers for large horizontal axis wind turbines, machines with a rotor axis height above 30 meters and rated at more than 500 kW, have varied in configuration, materials of construction, type of construction, height, and stiffness. For example, the U.S. large HAWTs have utilized steel truss type towers and free-standing steel cylindrical towers. In Europe, the trend has been to use only free-standing and guyed cylindrical towers, but both steel and reinforced concrete have been used as materials of construction. These variations in materials of construction and type of construction reflect different engineering approaches to the design of cost effective towers for large HAWTs. Tower designs are the NASA/DOE Mod-5B presently being fabricated. Design goals and requirements that influence tower configuration, height and materials are discussed. In particular, experiences with United States large wind turbine towers are elucidated. Finally, current trends in tower designs for large HAWTs are highlighted

    Osteocytes and mechanical loading: The Wnt connection

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    Bone adapts to the mechanical forces that it experiences. Orthodontic tooth movement harnesses the cell‐ and tissue‐level properties of mechanotransduction to achieve alignment and reorganization of the dentition. However, the mechanisms of action that permit bone resorption and formation in response to loads placed on the teeth are incompletely elucidated, though several mechanisms have been identified. Wnt/Lrp5 signalling in osteocytes is a key pathway that modulates bone tissue's response to load. Numerous mouse models that harbour knock‐in, knockout and transgenic/overexpression alleles targeting genes related to Wnt signalling point to the necessity of Wnt/Lrp5, and its localization to osteocytes, for proper mechanotransduction in bone. Alveolar bone is rich in osteocytes and is a highly mechanoresponsive tissue in which components of the canonical Wnt signalling cascade have been identified. As Wnt‐based agents become clinically available in the next several years, the major challenge that lies ahead will be to gain a more complete understanding of Wnt biology in alveolar bone so that improved/expedited tooth movement becomes a possibility

    Bounds on the Compactness of Neutron Stars from Brightness Oscillations

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    The discovery of high-amplitude brightness oscillations at the spin frequency or its first overtone in six neutron stars in low-mass X-ray binaries during type~1 X-ray bursts provides a powerful new way to constrain the compactness of these stars, and hence to constrain the equation of state of the dense matter in all neutron stars. Here we present the results of general relativistic calculations of the maximum fractional rms amplitudes that can be observed during bursts. In particular, we determine the dependence of the amplitude on the compactness of the star, the angular dependence of the emission from the surface, the rotational velocity at the stellar surface, and whether there are one or two emitting poles. We show that if two poles are emitting, as is strongly indicated by independent evidence in 4U 1636-536 and KS 1731-26, the resulting limits on the compactness of the star can be extremely restrictive. We also discuss the expected amplitudes of X-ray color oscillations and the observational signatures necessary to derive convincing constraints on neutron star compactness from the amplitudes of burst oscillations.Comment: 8 pages plus one figure, AASTeX v. 4.0, submitted to The Astrophysical Journal Letter

    New method of estimating the age of Niagara Falls /

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    Reprinted from Appleton's popular science monthly for June, 1899.Includes bibliographical references

    Tributes to Professor Robert Berkley Harper

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    In 1977, I began teaching at The University of Pittsburgh Law School and in short order one of my closest friends during my tenure there was Professor Robert “Bob” Harper. I wondered when I was hired whether I was selected because I looked strikingly similar to Bob, and perhaps the faculty thought my favoring Professor Harper would make my assimilation into the law school faculty that much easier. Students constantly called me Professor Harper and, indeed, many on the faculty called me Bob for several years; I never bothered to correct them. I thought if they paid that little attention to detail in law school, I would just let them go through life missing some of the finer points their education, and life for that matter, has to offer

    Snap it Up! / words by Frederick G. Johnson

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    Cover: caricatures of two African American males -- one playing banjo and the other dancing; description reads minstrel opening and closing chorus; Publisher: Wilkes-Barre: Frederick G. Johnson Publisherhttps://egrove.olemiss.edu/sharris_d/1102/thumbnail.jp

    Analysis and design of a capsule landing system and surface vehicle control system for Mars exploration

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    A number of problems related to unmanned exploration of planets or other extraterrestrial bodies with Mars as a case in point were investigated. The design and evaluation of a prototype rover concept with emphasis on mobility, maneuverability, stability, control and propulsion is described along with the development of terrain sensor concepts and associated software for the autonomous control of any planetary rover. Results are applicable not only to the design of a mission rover but the vehicle is used as a test bed for the rigorous evaluation of alternative autonomous control systems

    Effect of rotor configuration on guyed tower and foundation designs and estimated costs for intermediate site horizontal axis wind turbines

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    Three designs of a guyed cylindrical tower and its foundation for an intermediate size horizontal axis wind turbine generator are discussed. The primary difference in the three designs is the configuration of the rotor. Two configurations are two-blade rotors with teetering hubs - one with full span pitchable blades, the other with fixed pitch blades. The third configuration is a three-bladed rotor with a rigid hub and fixed pitch blades. In all configurations the diameter of the rotor is 38 meters and the axis of rotation is 30.4 meters above grade, and the power output is 200 kW and 400 kW. For each configuration the design is based upon for the most severe loading condition either operating wind or hurricane conditions. The diameter of the tower is selected to be 1.5 meters (since it was determined that this would provide sufficient space for access ladders within the tower) with guy rods attached at 10.7 meters above grade. Completing a design requires selecting the required thicknesses of the various cylindrical segments, the number and diameter of the guy rods, the number and size of soil anchors, and the size of the central foundation. The lower natural frequencies of vibration are determined for each design to ensure that operation near resonance does not occur. Finally, a cost estimate is prepared for each design. A preliminary design and cost estimate of a cantilever tower (cylindrical and not guyed) and its foundation is also presented for each of the three configurations
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