New Distribution Records for Mosquitoes in Michigan (Diptera: Culicidae)

(excerpt) Since the late 1940\u27s very little information has appeared in the literature dealing with the geographical distribution of mosquitoes in Michigan. The earliest attempt at establish- ing a comprehensive list of species was made by Irwin (1941) who catalogued 43 species by county. A survey by Pederson (1947) resulted in the collection of 48 species and provided the most extensive distribution list of mosquitoes in Michigan. Recent studies by Newson et al. (1975), McGroarty et al. (1976) and Grimstad (1977) have contributed several new distribution and state records. Prompted by the 1975 St. Louis encephalitis outbreak in Michigan, and a lack of current information on the species of mosquitoes in Isabella County, a survey of mosquitoes was conducted in the Mount Pleasant area

The Controversy of Myopia as a Risk Factor for Glaucoma: a Mathematical Approach

poster abstractPurpose: to quantify how individual variations in anatomical parameters often associated with myopia (e.g. longer ocular axial length (OAL), reduced scleral thickness (ST), lamina cribrosa diameter (LCD) and thickness (LCT)) affect retinal blood flow (RBF) and its sensitivity to ocular perfusion pressure (OPP). Methods: A mathematical model is used to calculate RBF through central retinal artery (CRA), arterioles, capillaries, venules, and central retinal vein (CRV). The flow is time-dependent, driven by systemic pressure and regulated by variable resistances to account for nonlinear effects due to (1) autoregulation (AR), and (2) lamina cribrosa effect on CRA and CRV. The latter is a nonlinear function of intraocular pressure (IOP), cerebrospinal fluid pressure (CSF) and OAL, ST, LCD, and LCT. RBF is computed as the solution of a system of five non-linear ordinary differential equations. The system is solved for different OPP values, obtained by varying independently IOP and mean arterial pressure (MAP), with and without AR. Results: Four representative eyes are compared: Eye 1 (OAL=24mm, ST=1mm, LCD=3mm, LCT=0.4mm), Eye 2 (OAL=28mm, ST=1mm, LCD=3mm, LCT=0.4mm), Eye 3 (OAL=24mm, ST=0.7mm, LCD=2mm, LCT=0.2mm), Eye 4 (OAL=28mm, ST=0.7mm, LCD=2mm, LCT=0.2mm). The model predicts that the cardiac cycle RBF average (RBFav) for eyes with smaller LCD and LCT is notably less than in normal eyes when IOP is elevated and without AR (c). Without AR and reduced MAP, the four eyes show similar RBFav reductions (d). With AR, anatomical changes do not induce notable changes in RBFav, (a) and (b). Conclusions: Reduced LCD and LCT, often associated with myopia, seem to affect RBFav more than elevated OAL. RBFav reductions magnify when AR is impaired, and this might reduce IOP safe levels for eyes with reduced LCD and LCT. These findings suggest that a combination of anatomical and vascular factors might cause certain myopic eyes to be at higher risk for glaucomatous damage than others

de Sitter Supersymmetry Revisited

We present the basic $\mathcal{N} =1$ superconformal field theories in four-dimensional de Sitter space-time, namely the non-abelian super Yang-Mills theory and the chiral multiplet theory with gauge interactions or cubic superpotential. These theories have eight supercharges and are invariant under the full $SO(4,2)$ group of conformal symmetries, which includes the de Sitter isometry group $SO(4,1)$ as a subgroup. The theories are ghost-free and the anti-commutator $\sum_\alpha\{Q_\alpha, Q^{\alpha\dagger}\}$ is positive. SUSY Ward identities uniquely select the Bunch-Davies vacuum state. This vacuum state is invariant under superconformal transformations, despite the fact that de Sitter space has non-zero Hawking temperature. The $\mathcal{N}=1$ theories are classically invariant under the $SU(2,2|1)$ superconformal group, but this symmetry is broken by radiative corrections. However, no such difficulty is expected in the $\mathcal{N}=4$ theory, which is presented in appendix B.Comment: 21 pages, 2 figure

Heterotic Flux Attractors

We find attractor equations describing moduli stabilization for heterotic compactifications with generic SU(3)-structure. Complex structure and K\"ahler moduli are treated on equal footing by using SU(3)xSU(3)-structure at intermediate steps. All independent vacuum data, including VEVs of the stabilized moduli, is encoded in a pair of generating functions that depend on fluxes alone. We work out an explicit example that illustrates our methods.Comment: 37 pages, references and clarifications adde

Actin cortex architecture regulates cell surface tension

Animal cell shape is largely determined by the cortex, a thin actin network underlying the plasma membrane in which myosin-driven stresses generate contractile tension. Tension gradients result in local contractions and drive cell deformations. Previous cortical tension regulation studies have focused on myosin motors. Here, we show that cortical actin network architecture is equally important. First, we observe that actin cortex thickness and tension are inversely correlated during cell-cycle progression. We then show that the actin filament length regulators CFL1, CAPZB and DIAPH1 regulate mitotic cortex thickness and find that both increasing and decreasing thickness decreases tension in mitosis. This suggests that the mitotic cortex is poised close to a tension maximum. Finally, using a computational model, we identify a physical mechanism by which maximum tension is achieved at intermediate actin filament lengths. Our results indicate that actin network architecture, alongside myosin activity, is key to cell surface tension regulation

Hypermoduli Stabilization, Flux Attractors, and Generating Functions

We study stabilization of hypermoduli with emphasis on the effects of generalized fluxes. We find a class of no-scale vacua described by ISD conditions even in the presence of geometric flux. The associated flux attractor equations can be integrated by a generating function with the property that the hypermoduli are determined by a simple extremization principle. We work out several orbifold examples where all vector moduli and many hypermoduli are stabilized, with VEVs given explicitly in terms of fluxes.Comment: 45 pages, no figures; Version submitted to JHE

A second look at N=1 supersymmetric AdS_4 vacua of type IIA supergravity

We show that a class of type IIA vacua recently found within the N=4 effective approach corresponds to compactification on Ads_4 \times S^3 \times S^3/Z_2^3. The results obtained using the effective method completely match the general ten-dimensional analysis for the existence of N=1 warped compactifications on Ads_4 \times M_6. In particular, we verify that the internal metric is nearly-Kahler and that for specific values of the parameters the Bianchi identity of the RR 2-form is fulfilled without sources. For another range of parameters, including the massless case, the Bianchi identity is satisfied when D6-branes are introduced. Solving the tadpole cancellation conditions in D=4 we are able to find examples of appropriate sets of branes. In the second part of this paper we describe how an example with internal space CP^3 but with non nearly-Kahler metric fits into the general analysis of flux vacua.Comment: Latex file, 35 pages, no figures. Reference added, minor corrections adde

Moduli Stabilization and Cosmology of Type IIB on SU(2)-Structure Orientifolds

We consider type IIB flux compactifications on six-dimensional SU(2)-structure manifolds with O5- and O7-planes. These six-dimensional spaces allow not only for F_3 and H_3 fluxes but also for F_1 and F_5 fluxes. We derive the four-dimensional N=1 scalar potential for such compactifications and present one explicit example of a fully stabilized AdS vacuum with large volume and small string coupling. We then discuss cosmological aspects of these compactifications and derive several no-go theorems that forbid dS vacua and slow-roll inflation under certain conditions. We also study concrete examples of cosets and twisted tori and find that our no-go theorems forbid dS vacua and slow-roll inflation in all but one of them. For the latter we find a dS critical point with \epsilon numerically zero. However, the point has two tachyons and eta-parameter \eta \approx -3.1.Comment: 35 pages + appendices, LaTeX2e; v2: numerical dS extremum added, typos corrected, references adde

Black holes and black branes in Lifshitz spacetimes

We construct analytic solutions describing black holes and black branes in asymptotically Lifshitz spacetimes with arbitrary dynamical exponent z and for arbitrary number of dimensions. The model considered consists of Einstein gravity with negative cosmological constant, a scalar, and N U(1) gauge fields with dilatonic-like couplings. We study the phase diagrams and thermodynamic instabilities of the solution, and find qualitative differences between the cases with 12.Comment: 27 pages, 10 figures; v2 references added, minor comments adde

Lifshitz black holes in string theory

We provide the first black hole solutions with Lifshitz asymptotics found in string theory. These are expected to be dual to models enjoying anisotropic scale invariance with dynamical exponent z=2 at finite temperature. We employ a consistent truncation of type IIB supergravity to four dimensions with an arbitrary 5-dimensional Einstein manifold times a circle as internal geometry. New interesting features are found that significantly differ from previous results in phenomenological models. In particular, small black holes are shown to be thermodynamically unstable, analogously to the usual AdS-Schwarzschild black holes, and extremality is never reached. This signals a possible Hawking-Page like phase transition at low temperatures.Comment: 19 pages, 7 figures. v2 references adde